الصفحة 1
الصفحة 1
On the move to meaningful internet systemss 2005 : CoopIS, DOA, and ODBASE ; Vol. 3760 : OTM Confederated International Conferences, CoopIS, DOA, and ODBASE 2005, Agia Napa, Cyprus, October 31 - November 4, 2005, Proceedings Part I
such as the modeling of (legal) regulatory systems and the ubiquitous nature of their usage. Weweregladto seethatin 2005undertheinspiredleadershipofDr. Pilar Herrero, several of earlier successful workshops re-emerged with a second or even third edition (notably WOSE, MIOS-INTEROP and GADA), and that 5 new workshops could be hosted and successfully organized by their respective proposers: AWeSOMe, SWWS, CAMS, ORM and SeBGIS. .
Object-Oriented Technology ; ECOOP 2006 Workshop Reader ; ECOOP 2006 Workshops, Nantes, France, July 3-7, 2006, Final Reports
ECOOP Workshop Reader, a c- pendium of workshop reports pertaining to the ECOOP 2006 conference, held in Nantes during July 3–7, 2006. ECOOP 2006 hosted 19 high-quality research workshops covering a large spectrum of hot research topics. These workshops were chosen through a tight peer review process following a speci?c call for proposals.
Object-Oriented Technology ; ECOOP 2001 Workshops, Panel, and Posters, Budapest, Hungary, June 18-22, 2001. Proceedings
For the ?fth time in its history, in cooperation with Springer-Verlag, the European C- ference on Object-Oriented Programming (ECOOP) conference series is glad to offer the object-oriented research community the ECOOP 2001 Workshop Reader, a c- pendium of workshop reports, panel transcripts, and poster abstracts pertaining to the ECOOP 2001 conference, held in Budapest from 18 to 22 June, 2001. ECOOP 2001 hosted 19 high-quality workshops covering a large spectrum of - search topics. The workshops attracted 460 participants on the ?rst two days of the conference. Originally 22 workshops were chosen from 26 proposals by a workshop selection committee, following a peer review process. Due to the overlaps in the areas of interest and the suggestions made by the committee six of the groups decided to merge their topicsintothreeworkshops.
Nitrogen-fixing Actinorhizal Symbioses
This book is the self-contained sixth volume of a comprehensive series on nitrogen fixation. It presents the state-of-the-art in regards to actinorhizal symbioses. Like legumes, actinorhizal plants form root nodules that host nitrogen-fixing soil bacteria. However, because the macrosymbionts are, with one exception, woody plants rather than crop plants, actinorhizal symbioses are less well-known than legume symbioses to which they are phylogenetically related. Actinorhizal plants come from eight different families. This volume includes chapters that deal with all these aspects of the symbiosis and both symbionts plus their ecological role and use. Other chapters tackle the global distribution of different actinorhizal plants and their microsymbionts and how this impacts the question of co-evolution of the micro- and macrosymbionts as well as comparing the actinorhizal and leguminous symbioses.
New Insights in Medical Mycology
The aim of this book is to give an in-depth assessment of our current understanding of the Biology of the main fungal pathogens and how they interact with the host’s immune response. Each Chapter focuses on a specific fungal pathogen or group of pathogens and examines their biology and the factors that allow the fungus colonise and disseminate within the host. In addition each Chapter gives an indication of the challenges that remain to be tackled over the next 5 – 10 years in increasing our understanding of fungal pathogenicity.
New and emerging plant viruses : the threat to food security
Despite intensive efforts to manage and prevent plant viruses and their potential vectors in crop production processes, many crops are damaged each year. This new book reviews the progress made to date and the challenges ahead in the field of plant viruses and agricultural production. It sheds light on previously undiscovered plant viruses, bringing together information on the detection and tracking, host interaction, evolution, and management. The first section covers the various hidden sources of plant viruses such as from wild plants, weeds, and tobacco as well as other undetermined plant virus sources. The second section covers the implications of mixed infection on disease pathogenicity and epidemiology, provides an understanding of the virus and host relationship, and presents an overview of plant viruses from old to new.
Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity
This comprehensive volume, written by experts in the integrative fields of neuroscience, endocrinology and immunology, provides insight into the mechanisms by which neural and neuroendocrine factors influence susceptibility to infection and autoimmunity. The book focuses on multiple sclerosis as the prototypic autoimmune disease and discusses infectious diseases including anthrax, influenza virus, herpes virus and human immunodeficiency virus. The effects of stress on experimental models of multiple sclerosis and also clinical observations of stress in multiple sclerosis patients are discussed. Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity is an ideal book for researches and professionals in the fields of immunology, neuroscience, infectious disease, psychology, microbiology, virology, public health and pharmaceutical sciences.
NETWORKING 2007. Ad Hoc and sensor networks, wireless networks, next generation internet ; 6th International IFIP-TC6 Networking Conference, Atlanta, GA, USA, May 14-18, 2007, Proceedings
This book constitutes the refereed proceedings of the 7th International IFIP-TC6 Networking Conference, NETWORKING 2008, held in Singapore, in May 2008.
Network Control and Engineering for QOS, Security and Mobility, III ; IFIP TC6 / WG6.2, 6.6, 6.7 and 6.8. Third International Conference on Network Control and Engineering for QoS, Security and Mobility, NetCon 2004 on November 2-5, 2004, Palma de Mallorca, Spain
This volume contains the proceedings of the Third International Conference on Network Control and Engineering for Quality of Service, Security and Mobility (Net-Con'2004), celebrated in Palma de Mallorca (Illes Balears, Spain) during November 2-5, 2004. This IFIP TC6 Conference was organized by the Universitat de les Illes Balears and sponsored by the following Working Groups: WG6.2 (Network and Internetwork Architectures), WG6.6 (Management of Networks and Distributed Systems), WG6.7 (Smart Networks) and WG6.8 (Mobile and Wireless Communications). The rapid evolution of the networking industry introduces new exciting challenges that need to be explored by the research community. The adoption of Internet as the global network infrastructure places the issue of quality of service among one of the hot topics nowadays: a huge diversity of applications with quite different service requirements must be supported over a basic core of protocols. Also, the open and uncontrolled nature of Internet enforces the need to guarantee secure transactions among users, thus placing security as another hot topic. Finally, the explosion of mobility and its integration as part of the global infrastructure are probably now the most challenging issues in the networking field.
Mycorrhizae : Sustainable Agriculture and Forestry
This book discusses and goes into detail on a number of topics: the molecular basis of nutrient exchange between arbuscular mycorrhizal (AM) fungi and host plants; the role of AM fungi in disease protection, alleviation of soil stresses and increasing grain production; interactions of AM fungi and beneficial saprophytic mycoflora in terms of plant growth promotion; the role of AM fungi in the restoration of native ecosystems; indirect contributions of AM fungi and soil aggregation to plant growth and mycorrhizosphere effect of multitrophic interaction; the mechanisms by which mycorrhizas change a disturbed ecosystem into productive land; the importance of reinstallation of mycorrhizal systems in the rhizosphere is emphasized and their impact on landscape regeneration, and in bioremediation of contaminated soils; Ectomycorrhizae (ECM) and their importance in forest ecosystems and associations of ECM in tropical rain forests function to maintain tropical monodominance; in vitro mycorrhization of micro-propagated plants, and visualizing and quantifying endorhizal fungi; the use of mycorrhizae, mainly AM and ECM, for sustainable agriculture and forestry.
Multi-Scale Approaches in Drug Discovery : From Empirical Knowledge to In silico Experiments and Back
Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents.
Multifunctional Pharmaceutical Nanocarriers
Various pharmaceutical nanocarriers, such as nanospheres,nanocapsules, liposomes, micelles, cell ghosts, lipoproteins and some others are widely used for experimental (and already clinical) delivery of therapeutic and diagnostic agents. The use of nanoparticulate pharmaceutical carriers to enhance the in vivo efficiency of many drugs well established itself over the past decade both in pharmaceutical research and clinical setting.
Multidetector-Row CT of the Thorax
With the advent of multidetector-row technology, excitement has returned to computed tomography. Not only can we now image faster and with better resolution than ever before; more importantly, the development of sophisticated image acquisition techniques has enabled us to venture into areas previously considered to be beyond the scope of CT imaging. The knowledge, experience, and vision of a host of renowned international experts in cutting-edge thoracic applications of multidetector-row CT are condensed within this book. The result is a critical, comprehensive review of the novel opportunities, but also the new challenges, brought about by the development of ever-faster CT acquisition techniques.
Molecular Mimicry : Infection Inducing Autoimmune Disease
The conceptual basis for molecular mimicry was first defined in the early 1980s when monoclonal antibodies against viruses were also shown to react with non-viral host protein; in this case, measles virus phosphoprotein cross-reacted with host cell cytokeratin, herpes simplex virus type 1 with host-cell vimentin and vaccinia virus with host-cell intermediate filaments. Following this discovery, others emerged, again at the clonal level, that T cell clones against proteins from a variety of infectious agents also reacted with host antigenic determinants. The clonal distinction was imperative fo.
Molecular Mechanisms of Parasite Invasion
All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.
Molecular Gas Dynamics : Theory, Techniques, and Applications
This self-contained work is an up-to-date treatment of the basic theory of molecular gas dynamics and its various applications. Recent progress in the field has greatly enhanced the original theory and stimulated interesting and critical gas dynamic phenomena and problems. This book, unique in the literature, presents working knowledge, theory, techniques, and typical phenomena in rarefied gases for theoretical development and applications.
Molecular and Cellular Signaling
A small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determine what kinds of cells are made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders to cancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer. Molecular and Cellular Signaling provides an introduction to molecular and cellular signaling in biological systems with an emphasis on the underlying physical principles. The text is aimed at upper-level undergraduates, graduate students and individuals in medicine and pharmacology interested in broadening their understanding of how cells regulate and coordinate their core activities and how diseases arise when these regulatory systems malfunction, as well as those in chemistry, physics and computer science interested in pursuing careers in biological and medical physics, bioinformatics and systems biology. To that end, the book includes background information and review sections, and chapters on signaling in the immune, endocrine (hormonal) and nervous systems. It has chapters on cancer, apoptosis and gene regulation, and contains chapters on bacteria and viruses. In those chapters not specifically devoted to pathogens, connections between diseases, drugs and signaling are made. Each chapter also features a problem set to facilitate further discussion and understanding.
Modulation of host gene expression and innate immunity by viruses
This book is reference on a relatively young area of research in which virology, cellular biology and molecular pathogenesis govern the principles of coinvestigation. Infection of a naïve (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity). The outcome of this interaction is influenced by the genes of the virus as well as the genes of the host. Interestingly, different viruses do it in different ways. Not only is there a plethora of mechanisms used by the invading organisms, but the host has also evolved a great variety of redundant and robust countermeasures. This interplay of host and virus represents one of the most significant frontiers in biology today. A clearer understanding of the mechanisms involved will arm us with better strategies to deal with viruses, including emerging pathogens and potential bioterrorism agents. This book is sure to benefit students, scientists, and physicians working in the areas of virology, immunology, microbiology, and infectious diseases.
Modeling, Control and Implementation of Smart Structures : A FEM-State Space Approach
This monograph presents an introductory overview of smart structures, their concepts, their active involvement in the vibration control, their applications and the extensive research work done on it so far. The modelling of flexible beams using two types of beam theories, viz., the Euler-Bernoulli theory and the Timoshenko beam theory is presented, including a new concept of finite element modeling of the flexible structures using Timoshenko beam theory with the inclusion of the shear both in the piezo-patches as well as in the host structure. It presents the design of the periodic output feedback control system for smart structure systems, the design of the FOS controllers for active vibration control and the design of Discrete Sliding Mode controllers using multirate output feedback technique.
Model-Driven Architecture - Foundations and Applications ; 2nd European Conference, ECMDA-FA 2006, Bilbao, Spain, July 10-13, 2006, Proceedings
The goal of the European Conference on Model-Driven Architecture — Foundations and Applications (ECMDA-FA) is to bring together industry and academia to tackle the problems in model-driven development. This volume includes 18 foundation papers and 12 application papers, which is a fine balance between both worlds. ECMDA-FA 2006 also hosted six workshops on both theoretical and practical aspects of MDA. Furthermore, the keynote speakers, David Frankel and Bran Selic, from some of the world’s largest IT companies proved that industry is very much involved in MDA. This second ECMDA-FA conference is the result of the work of the authors who submitted a total of 78 papers, the Program Committee members who took the effort to review the papers, the people organizing the workshops, and of course the Steering Committee. All in all, several hundreds of people have worked hard to make this conference a success.
