الصفحة 1
الصفحة 1
Molecular mechanisms in nutritional epigenetics
The field of nutritional epigenetics/nutri-epigenetics has expanded significantly, shedding light on how environmentally-driven epigenetic pathways can be modulated through nutrition and eating habits. The book provides a comprehensive introduction to the various epigenetic mechanisms affected by dietary compounds and focuses on specific topics such as the relationship between diet and the gut microbiome, the impact of diet on cardiovascular disease and psychopathology and the role of diet in pregnancy.
Computational Discovery of Scientific Knowledge : Introduction, Techniques, and Applications in Environmental and Life Sciences
Advances in technology have enabled the collection of data from scientific observations, simulations, and experiments at an ever-increasing pace. For the scientist and engineer to benefit from these enhanced data collecting capabilities, it is becoming clear that semi-automated data analysis techniques must be applied to find the useful information in the data. Computational scientific discovery methods can be used to this end: they focus on applying computational methods to automate scientific activities, such as finding laws from observational data. In contrast to mining scientific data, which focuses on building highly predictive models, computational scientific discovery puts a strong emphasis on discovering knowledge represented in formalisms used by scientists and engineers, such as numeric equations and reaction pathways. This state-of-the-art survey provides an introduction to computational approaches to the discovery of scientific knowledge and gives an overview of recent advances in this area, including techniques and applications in environmental and life sciences.
Aging and Senescence
Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies, including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. Aging research has experienced an unprecedented advance over recent years, particularly with the discovery that the rate of aging is controlled, at least to some extent, by genetic pathways and biochemical processes conserved in evolution. Although recent developments in molecular biology are far from understanding the biological basis of aging, research suggests that targeting the aging process itself could ameliorate many age-related pathologies.
