الصفحة 1
الصفحة 1
Zoonosi e sanità pubblica : Un approccio interdisciplinare per un problema emergente = Zoonosis and Public Health: An Interdisciplinary Approach to an Emerging Problem
Zoonoses, that is, naturally transmissible infections between other animal species and man, are now an emerging problem, even in developed countries. Climate change, human migration flows, growth in international trade and wars favor both the re-emergence of diseases considered rare and the introduction of potentially pathogenic organisms into new geographical areas. For most of these pathologies, however, the majority of health professionals - starting with general practitioners - often do not have appropriate and up-to-date knowledge and tools. The text aims to provide medical personnel - and primarily general practitioners - with both a scientific and regulatory framework and a series of specific and practical information on individual pathologies. This volume is intended to be an operational tool also aimed at encouraging multidisciplinary collaboration and the exchange of information, in particular between doctors and veterinarians.
What are the optimal strategies for managing avulsed permanent teeth?
Dental avulsion is considered the most severe form of traumatic tooth injury, as it involves damage to multiple structures and results in the tooth being completely displaced from its socket. Effective management protocols for avulsed teeth should address both the pulp and periodontal ligament (PDL) cells to enhance the long-term and survival of these teeth.
Weißbuch Multiple Sklerose : Versorgungssituation in Deutschland = Multiple sclerosis white paper : Supply situation in Germany
Multiple sclerosis (MS) is the most common inflammatory degenerative disease of the central nervous system in young adults. To date, the disease cannot be cured. A number of new therapeutic options have emerged in recent years. The aim of this white paper is to present current knowledge about the disease MS and its care in Germany objectively and comprehensively. It contains Information on the clinical picture, on the epidemiology and on its health-economic relevance. Current developments and treatment recommendations are compared to the real use and the existing capacities of diagnostic and therapeutic options.
Venous Thromboembolism : Prevention and Treatment
Pulmonary thromboembolism in Japan is currently associated with a high mortality rate and remains a concern for patients and medical staff alike. Moreover, as the mechanisms of the condition have been elucidated, it has become clear that much work needs to be done in the field to achieve acceptable results in this country. Thus, Japan has regularly played host to the International Symposium on Pulmonary Thromboembolism . At the most recent symposium, in Sendai, the epidemiology and the treatment of pulmonary thromboembolism, traveler's thrombosis, and the prevention of deep vein thromboembolism were discussed, particularly with reference to the differences between Japan and Western countries. The fruits of the collaboration between that assembly of international specialists can be found in this collection of work. It provides an in-depth look at the current concepts that guide the treatment and prevention of the disease, and at the problem areas that must be improved upon.
Vascular Surgery
Edited by prominent vascular surgeons in the USA and UK, the book tackles the epidemiology and etiology of atherosclerosis and how to evaluate patients with vascular disease. Specific vascular diseases are then covered and their treatment options discussed. Vascular Surgery adopts a transatlantic approach so that chapters are written either by a practitioner in the USA or UK, and each chapter is critically appraised by a colleague who provides a potentially alternative perspective. This book is key reading for trainees in vascular surgery, as well as for surgery trainees in general. It would also be useful to those who have already qualified but might need further knowledge of this important field.
Tumors of the Chest : Biology, Diagnosis and Management
The purpose of the textbook, Tumors of the Chest: Biology, Diagnosis and Management, is to meticulously depict all aspects of chest tumors in a comprehensive volume format that encompasses their biology, clinical presentation and management. Lung cancer and chest malignancies demand complicated therapeutical procedures without a guaranteed cure, cause agonizing side effects and mean immense suffering for the patients and their families. Over the last decade lung cancer became the providence of the scientific specialities involved:oncology, radiology, radiotherapy, palliative, epidemiology, biology. The internationally renowned authors provide in this book a comprehensive and interdisciplinary overview of their experience with the latest advances in these fields. Also covered are the wide-ranging topics of management in the elderly, chemoprevention, along with ethical, social and economic issues.
Tumor Prevention and Genetics III
Identification of cancer risk factors and potential prevention strategies have been some of the most important medical and research contributions to the improvement of public health in the past half-century (Steele 2003). Understanding the role of lifestyle, exposure to endogenous factors and exogenous environmental factors, and individual genetic and epigenetic variability have contributed significantly to this effort. Cancer prevention strategies have been developed based on results of epidemiologic, preclinical, and clinical studies that have generated clues for identifying risk factors that may be modulated by changes in lifestyle, such as smoking cessation or dietary modification (Greenwald 2002a). In addition, significant progress in medical interventions involving chemoprevention—a pharmacological approach to intervention that aims to prevent, arrest, or reverse either the initiation phase of carcinogenesis or the progression of premalignant cells—is beginning to pay dividends in reducing risks associated with cancer.
Tuberculosis in Adults and Children
Contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.
Treating Trichotillomania : Cognitive-Behavioral Therapy for Hairpulling and Related Problems
Trichotillomania has been described in the literature for at least a hundred years, but has only in the past decade received serious clinical attention. Although now a "higher profile" disorder, there is still scant clinical information on trichotillomania. A full-length cognitive-behavioral treatment manual, Treating Trichotillomania (TTM) fills that need. Designing the book for maximum usefulness, authors Franklin and Tolin share their considerable expertise in treating body-focused repetitive behavior disorders (not only hair-pulling but skin-picking and nail-biting as well) in an accessible, clinically valid reference. Treating Trichotillomania carefully defines TTM, differentiating the disorder from other conditions such as OCD, reviewing the varied clinical forms it can take, and setting out its diagnostic criteria.
Traité des infections et pathologies génitales à papillomavirus = Treated on genital papillomavirus infections and pathologies
The impact of papillomavirus (HPV) infection is considerable. More than one in two women has been exposed to HPV in her lifetime and about 10% will develop a chronic infection. Of these, 20% will develop cervical cancer in the absence (or failure) of screening. Optimization of screening and better management are now possible through the use of innovative techniques such as smear in liquid suspension and HPV testing. Because cervical cancer is the ultimate consequence of chronic HPV infection, we now have the extraordinary chance to prevent it with a prophylactic vaccine intended to protect women from the associated precancerous and cancerous HPV lesions, as well as condylomata acuminata. This resolutely practical and educational collective work takes stock of knowledge on HPV infection and its associated pathologies while deciphering the new issues and practices in the vaccine era.
Therapeutic Lipidology ; 2nd ed.
The chapters focus on recent advances in the field including novel biomarkers and the microbiome, genomics of cardiovascular risks, PCSK9 inhibitors, imaging technologies, and epidemiology of atherosclerotic cardiovascular disease. The book describes new guidelines, novel therapeutic agents, and changes in the understanding of specific lipoproteins and subclasses with regard to their relationships to cardiovascular disease risk. The second edition contains more than thirty chapters covering such topics as the history of lipidology, lipoprotein metabolism and vascular biology, disorders of lipid metabolism, lifestyle/dietary and pharmacologic management for dyslipidemia, the management of dyslipidemia in certain subgroups (e.g., women, children, older patients) and lipid testing, as well as an examination of other biomarkers and testing procedures related to atherosclerosis and cardiovascular disease.
The World of Rhabdoviruses
In this volume the unique and common features of rhabdoviruses, particularly their morphological, molecular, and pathogenic characteristics, and their phylogenetic relationships are reviewed. Rhabdoviruses have a very wide host range and have been isolated from plants, insects, and almost from all vertebrates including fish and primates. The Rhabdoviridae family consists of six genera which have all been associated with diseases. While rhabdoviruses that are etiological agents of human diseases can cause serious public health problems, other members of this family that infect domestic livestock and agricultural plants can also cause enormous economic loss.
The Surgery of Childhood Tumors
Beginning with the scientific basis of tumors, 'The Surgery of Childhood Tumors' provides up-to-date information on epidemiology, cytogenetics and molecular biology, before looking at current treatments, integrating surgery, neoadjuvant and adjuvant chemotherapy and radiation therapy. Additionally, a chapter on counseling reflects the book's holistic approach to treating children with cancer. The chapters are written by world-renowned international authorities on pediatric cancer from major children's cancer groups in the UK, Europe and the US. Contributors discuss geographical variations in treatment for each type of tumor. Excellent full-colour pictures and detailed line drawings illustrate all aspects of managing childhood tumors, including technical details of operation which are often neglected in other texts. This comprehensive book provides a contemporary approach for pediatric, general and urological surgeons dealing with childhood tumors. New chapters in this second edition provide the latest developments and strategies in pediatric surgical oncology.
The Statistics of Gene Mapping
This book presents a unified discussion of the statistical concepts applied in gene mapping, first in the experimental context of crosses of inbred lines and then in outbred populations, primarily humans.
The Polycystic Ovary Syndrome : Current Concepts on Pathogenesis and Clinical Care
Polycystic ovary syndrome (PCOS) is the single most common endocrinologic abnormality of women, affecting approximately 1 in 10-to 15 women of reproductive age. It is also the most frequent cause of oligo-ovulatory infertility. PCOS patients demonstrate androgenic symptoms including hirsutism, alopecia, and acne. Furthermore, patients with PCOS are at significant risk for developing diabetes, hypertension, dyslipidemia, and possibly cardiovascular disease. It is estimated that the healthcare cost exceeds four billion dollars annually in the United States alone, not even accounting for the significant negative effect this disorder has on quality of life.
The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes
World Health Organization data documents that infectious diseases and immunodeficiencies are the leading causes of morbidity and mortality in the world's children. In The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes, an authoritative, international panel of experts provide a succinct, up-to-date, evidence-based reference to the neurological consequences of infectious diseases and immunodeficiency syndromes in children in one readily accessible volume. Within each of its conveniently structured chapters, readers will find a general description of the disease or disorder, its epidemiology, etiology, clinical synopsis, neurological manifestations, diagnosis, differential diagnosis and therapy.
The Metabolic Syndrome and Obesity
The Metabolic Syndrome and Obesity presents an up-to-date survey of the current scientific understanding of obesity and the metabolic syndrome, as well as an overview of the most significant changes to the field over the past 30 years. By first presenting a historical context for overweight, the book drives home the point that obesity is by no means simply a contemporary problem, and its continued existence means that we neither understand it, nor have developed effective therapies. The Metabolic Syndrome and Obesity is a comprehensive reference for the treatment of obesity in two parts. Part I, The Problem, examines the entire scope of the obesity epidemic, including epidemiology and history, costs of treatment, pathology, clinical types, age-related issues, and general health risks. Part II, The Solutions, describes several treatment options including diet, behavior modification, exercise, pharmacological treatment, and surgery. This volume is a thorough reference for obesity and the metabolic syndrome and offers an in-depth assessment of the problem and its myriad potential treatment options.
The many faces of health, competence and well-being in old age : Integrating Epidemiological, Psychological and Social Perspectives
These key issues are addressed based on three converging research streams: social-ecological research, which assumes that major processes and outcomes of ageing such as day-to-day competence are shaped by social and physical-spatial environments; geropsychology research, which is driven by a life-span developmental conception of ageing; and epidemiology, which offers most fundamental disease, function and prevention-related data. Each of the three major research directions are outlined by a short introduction, followed by three chapters treating in an empirical manner most recent key research questions. All chapters are then also discussed by renowned ageing experts. This volume links ageing research with policy considerations and implications and establishes a link between European research and the knowledge base of the international scientific community concerned with ageing.
The Genus Yersinia : From Genomics to Function
Based on selected presentations from the meeting and contains both reviews and research articles. It is divided into six topic areas: 1) genomics; 2) structure and metabolism; 3) regulatory mechanisms; 4) pathogenesis and host interactions; 5) molecular epidemiology and detection; and 6) vaccine and antimicrobial therapy development. Consequently, this volume covers a wide range of current research areas in the Yersinia field.
The Frailty Model
Clustered survival data are encountered in many scientific disciplines including human and veterinary medicine, biology, epidemiology, public health and demography. Frailty models provide a powerful tool to analyse clustered survival data. In contrast to the large number of research publications on frailty models, relatively few statistical software packages contain frailty models.It is demanding for statistical practitioners and graduate students to grasp a good knowledge on frailty models from the existing literature. This book provides an in-depth discussion and explanation of the basics of frailty model methodology for such readers. The discussion includes parametric and semiparametric frailty models and accelerated failure time models. Common techniques to fit frailty models include the EM-algorithm, penalised likelihood techniques, Laplacian integration and Bayesian techniques. More advanced frailty models for hierarchical data are also included.
