الصفحة 1
الصفحة 1
Nutritional psychiatry
Provides a comprehensive overview of nutritional psychiatry, elucidating its theoretical foundations, the biological mechanisms linking diet to mental health (including inflammation, oxidative stress, disrupted energy metabolism the gut–brain axis and other implicated pathways), and the current evidence base for dietary impacts on major psychiatric disorders such as depression, anxiety, schizophrenia, bipolar disorder, and ADHD.
Intermittent fasting
The potential benefits of intermittent fasting are not limited to weight loss and weight management. Recent studies have shed light on its role in adaptive cellular responses that reduce oxidative damage and inflammation, optimize energy metabolism and bolster cellular protection. By reprogramming metabolic and stress resistance pathways, intermittent fasting has the possible ability to increase longevity and reduce aging. Studies on animals have given promising result that show how intermittent fasting help prevent and treat diseases like diabetes, cancers, heart disease and neurodegeneration. Major mechanisms hypothesized to link fasting regimens with human health: circadian biology and the gastrointestinal microbiota.
Hydrogenosomes and Mitosomes : Mitochondria of Anaerobic Eukaryotes
"Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes" provides a summary of the current knowledge of these organelles, which occur in unicellular, often parasitic organisms, including human pathogens. The distribution of these organelles is broad, but they were detected primarily in an anoxic habitat or nutrient rich intracellular niche that permits life without the efficient energy generating system of typical mitochondria. Their common characteristic is that they lack the aerobic energy conservation system of typical mitochondria and that they are usually the site of the synthesis of iron-sulfur clusters, regarded as the only indispensable function of eukaryotic mitochondria.These mitochondria-related organelles exhibit a variety of structures and functions. This work describes properties such as protein import, structure, metabolism, adaptation, proteome and their role in drug activation and resistance. Further topics include the evolution and biogenesis of these organelles.
Handbook of neurochemistry and molecular neurobiology : Brain Energetics. Integration of Molecular and Cellular Processes
Focuses on aspects of energy metabolism that are unique to the brain. The goal of each chapter is to provide a fundamental overview of each area, to define the state-of-the-art in that area as it relates to brain, and, where appropriate, describe models that portray poorly understood and apparently contradictory data sets with the goal of helping focus attention to experimental resolution of controversial issues.
Energy Metabolism and Obesity : Research and Clinical Applications
Elucidate the most important aspects of genetic background, neuropeptide secretion and action, neuronal pathways, adipokines, gut hormones, and environmental influences (physical activity, pharmacologic agents, and surgical alteration of the gastrointestinal tract), as well as the complex interactions among them.
Data Mining in Bioinformatics
8. 1. 1 Protein Subcellular Location The life sciences have entered the post-genome era where the focus of biological research has shifted from genome sequences to protein functionality. Withwhole-genomedraftsofmouseandhumaninhand,scientistsareputting more and more e?ort into obtaining information about the entire proteome in a given cell type. The properties of a protein include its amino acid sequences, its expression levels under various developmental stages and in di?erent tissues, its3Dstructure and activesites,its functionalandstructural binding partners, and its subcellular location. Protein subcellular location is important for understanding protein function inside the cell. For example, the observation that the product of a gene is localized in mitochondria will support the hypothesis that this protein or gene is involved in energy metabolism. Proteins localized in the cytoskeleton are probably involved in intracellular tra?cking and support.
Lehninger Principles of Biochemistry
Help students navigate the complex discipline of biochemistry with a clear and coherent presentation. Renowned authors David Nelson, Michael Cox, and new co-author Aaron Hoskins have focused this eighth edition around the fundamental principles to help students understand and navigate the most important aspects of biochemistry. Text features and digital resources in the new Achieve platform emphasize this focus on the principles, while coverage of recent discoveries and the most up-to-date research provide fascinating context for learning the dynamic discipline of biochemistry.
