الصفحة 1
الصفحة 1
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Open access databases and datasets for drug discovery

With an overview of 90 freely accessible databases and datasets on all aspects of drug design, development, and discovery, Open Access Databases and Datasets for Drug Discovery is a comprehensive guide to the vast amount of “free data” available to today’s pharmaceutical researchers. The applicability of open-source data for drug discovery and development is analyzed, and their usefulness in comparison with commercially available tools is evaluated. The most relevant databases for small molecules, drugs and druglike substances, ligand design, protein 3D structures (both experimental and calculated), and human drug targets are described in depth, including practical examples of how to access and work with the data. The first part is focused on databases for small molecules, followed by databases for macromolecular targets and diseases. The final part shows how to integrate various open-source tools into the academic and industrial drug discovery and development process.

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Ontology Matching

Euzenat and Shvaiko’s book is devoted to ontology matching as a solution to the semantic heterogeneity problem faced by computer systems. Ontology matching aims at finding correspondences between semantically related entities of different ontologies. These correspondences may stand for equivalence as well as other relations, such as consequence, subsumption, or disjointness, between ontology entities.

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Ontology Management : Semantic Web, Semantic Web Services, and Business Applications

This volume describes relevant tasks, practical and theoretical challenges, limitations and methodologies, plus available software tools. The editors discuss integrating the conceptual and technical dimensions with a business view on using ontologies, by stressing the cost dimension of ontology engineering and by providing guidance on how up-to-date tooling helps to build, maintain, and use ontologies.  Also included is a one-stop reference on all aspects of managing ontological data and best practices on ontology management for a number of application domains.

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Ontology Alignment : Bridging the Semantic Gap

Ontology Alignment: Bridging the Semantic Gap introduces novel methods and approaches for semantic integration. In addition to developing new methods for ontology alignment, the author provides extensive explanations of up-to-date case studies. The topic of this book, coupled with the application-focused methodology, will appeal to professionals from a number of different domains.

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Ontologies-Based Databases and Information Systems ; 1st and Second VLDB Workshops, ODBIS 2005/2006 Trondheim, Norway, September 2-3, 2005 Seoul, Korea, September 11, 2006 Revised Papers

This book constitutes the refereed post-proceedings of the First and Second VLDB Workshop Ontologies-based techniques for DataBases and Information Systems, held in Trondheim, Norway, September 2005 and Seoul, Korea, September 2006.

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Ontologies for Urban Development

Action C21 of the European programme for Cooperation in the field of Scientific and Technical Research (COST—http://www.cost.esf.org/) is dedicated to investigating urban ontologies for an improved communication in urban civil engineering projects. The Action, known informally as "Towntology", brings together a large and heterogeneous grouping from across Europe, whose interests range from construction to urban tourism and from transport infrastructure to resource visualisation. On 6-7 November 2006, in Geneva, the Action convened a successful workshop to address emerging issues in the field. This volume presents the contributions to that workshop, in many cases revised afterwards to capture some of the outcomes of discussion.

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Ontologies : A Handbook of Principles, Concepts and Applications in Information Systems

The primary objective of ONTOLOGIES: A Handbook of Principles, Concepts and Applications in Information Systems is to mobilize a collective awareness in the research community to the leading and emerging developments in ODIS, and consequently, highlight the enormous potential of ODIS research to both fundamentally transform and create innovative solutions to several problems in various domains. This book is a compilation of 32 leading-edge chapter contributions from some of the top researchers in the community working in various fundamental and applied disciplines related to ODIS. These chapters are organized into four broad themes: Foundations of ODIS, Ontological Engineering, ODIS Architectures, and ODIS Applications.

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Oncology : An Evidence-Based Approach

Reflect the principles and current practice of oncology with contributors from the fields of medical, surgical, and radiation oncology. The textbook will incorporate an evidence-based approach, enabling the reader to make decisions on the basis of concrete data. Sections on solid tumors, hematologic malignancies and the practice of oncology address the natural history and therapy for the full spectrum of neoplastic diseases in the adult. Further sections present fundamentals of supportive care of the cancer patient, the management of oncologic emergencies and acute toxicities of therapy, as well as care of metastatic disease and the terminally-ill patient. Breaking new ground, the textbook features thoughtful, in-depth sections on cancer prevention and control, cancer surviorship, the economics of cancer care, and cancer informatics. Cancer imaging is covered with an organ system-based approach, with an additional chapter on the especially intriguing potential of PET. Furthermore, a comprehensive section on translational basic science reviews the fundamentals of molecular biology, the cell cycle and signal transduction, carcinogenesis, cancer genetics, the biology of invations and metastasis, and tumor immunology.

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On the path to AI : Law’s prophecies and the conceptual foundations of the machine learning age

This book explores machine learning and its impact on how we make sense of the world. It does so by bringing together two ‘revolutions’ in a surprising analogy: the revolution of machine learning, which has placed computing on the path to artificial intelligence, and the revolution in thinking about the law that was spurred by Oliver Wendell Holmes Jr in the last two decades of the 19th century.

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On the move to meaningful internet systems 2007 : OTM 2007 Workshops ; OTM Confederated International Workshops and Posters, AWeSOMe, CAMS, OTM Academy Doctoral Consortium, MONET, OnToContent, ORM, PerSys, PPN, RDDS, SSWS, and SWWS 2007, Vilamoura, Portugal, November 25-30, 2007,

it is clear that there is an acute and increasing need to address and discuss in an integrated forum the implied software and system issues as well as methodological, semantical, theoretical and application issues. As we all know, e-mail, the Internet, and even video conferences are not sufficient for effective and efficient scientific exchange. This is why the OnTheMove (OTM) Federated Conferences series has been created to cover the increasingly wide yet closely connected range of fundamental technologies such as data and Web Semantics.

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On the move to meaningful internet systems 2007 : OTM 2007 Workshops ; OTM Confederated International Workshops and Posters, AWeSOMe, CAMS, OTM Academy Doctoral Consortium, MONET, On To Content, ORM, PerSys, PPN, RDDS, SSWS, and SWWS 2007, Vilamoura, Portugal, November 25-30, 2007, Proceedings, Part II

This two-volume set LNCS 4805/4806 constitutes the refereed proceedings of 10 international workshops and papers of the OTM Academy Doctoral Consortium held as part of OTM 2007 in Vilamoura, Portugal, in November 2007. The first volume begins with 23 additional revised short or poster papers of the OTM 2007 main conferences.

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On the move to meaningful internet systems 2007 : CoopIS, DOA, ODBASE, GADA, and IS ; OTM Confederated International Conferences, CoopIS, DOA, ODBASE, GADA, and IS 2007, Vilamoura, Portugal, November 25-30, 2007, Proceedings, Part II

This two-volume set LNCS 4803/4804 constitutes the refereed proceedings of the five confederated international conferences on Cooperative Information Systems (CoopIS 2007), Distributed Objects and Applications (DOA 2007), Ontologies, Databases and Applications of Semantics (ODBASE 2007), Grid computing, high performance and Distributed Applications (GADA 2007), and Information Security (IS 2007) held as OTM 2007 in Vilamoura, Portugal, in November 2007.

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On the move to meaningful internet systems 2007 : CoopIS, DOA, ODBASE, GADA, and IS ; OTM Confederated International Conferences, CoopIS, DOA, ODBASE, GADA, and IS 2007, Vilamoura, Portugal, November 25-30, 2007, Proceedings, Part I

Constitutes the proceedings of the 5 confederated international conferences on Cooperative Information Systems, Distributed Objects and Applications, Ontologies, Databases and Applications of Semantics, Grid computing, high performance and Distributed Applications, and Information Security held as OTM 2007 in Vilamoura, Portugal, in November 2007.

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On the move to meaningful internet systems 2006 : OTM 2006 Workshops ; Vol.4278 ; OTM Confederated International Conferences and Posters, AWeSOMe, CAMS, COMINF ,IS, KSinBIT, MIOS-CIAO, MONET, On To Content, ORM, PerSys, OTM Academy Doctoral Consortium, RDDS,SWWS,SeBGIS 2006, Montpellier, France, October 29 - November 3, 2006, Proceedings, Part II

This two-volume set LNCS 4277/4278 constitutes the refereed proceedings of 14 international workshops held as part of OTM 2006 in Montpellier, France in October/November 2006. The first volume begins with 26 additional revised short or poster papers of the OTM 2006 main conferences.

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On the move to meaningful internet systems 2006 : OTM 2006 Workshops ; Vol. 4277 ; OTM Confederated International Conferences and Posters, AWeSOMe, CAMS, COMINF, IS, KSinBIT, MIOS-CIAO, MONET, On To Content, ORM, PerSys, OTM Academy Doctoral Consortium, RDDS, SWWS, SeBGIS 2006, Montpellier, France, October 29 - November 3, 2006, Proceedings, Part I

This two-volume set LNCS 4277/4278 constitutes the refereed proceedings of 14 international workshops held as part of OTM 2006 in Montpellier, France in October/November 2006. The 191 revised full papers presented were carefully reviewed and selected from a total of 493 submissions to the workshops. The first volume begins with 26 additional revised short or poster papers of the OTM 2006 main conferences.

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On the move to meaningful internet systems 2006 : CoopIS, DOA, GADA, and ODBASE ; Vol. 4275 ; OTM Confederated International Conferences, CoopIS, DOA, GADA, and ODBASE 2006, Montpellier, France, October 29 - November 3, 2006, Proceedings, Part I

This two-volume set LNCS 4275/4276 constitutes the refereed proceedings of the four confederated conferences CoopIS 2006, DOA 2006, GADA 2006, and ODBASE 2006 held as OTM 2006 in Montpellier, France in October/November 2006. The 106 revised full and nine short papers presented together with four keynote speeches were carefully reviewed and selected from a total of 361 submissions.

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On the move to meaningful internet systems 2005 : OTM 2005 Workshops ; OTM Confederated International Workshops and Posters, AWeSOMe, CAMS, GADA. MIOS+INTEROP, ORM, PhDS, SeBGIS. SWWS. and WOSE 2005, Agia Napa, Cyprus, October 31 - November 4, 2005, Proceedings

This book constitutes the joint refereed proceedings of nine international workshops held as part of OTM 2005 in Agia Napa, Cyprus in October/November 2005.The 145 revised full papers presented were carefully reviewed and selected from a total of 268 submissions. Topics addressed are agents, Web services and ontologies merging (AWeSOMe 2005), context-aware mobile systems (CAMS 2005), grid computing and its application to data analysis (GADA 2005), inter-organizational systems and interoperability of enterprise software and applications (MIOS+INTEROP 2005), object-role modeling (ORM 2005), a PHD symposium (PhDS 2005), semantic-based geographical information systems (SeBGIS 2005), Web semantics (SWWS 2005), and ontologies, semantics and e-learning (WOSE 2005)

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On the move to meaningful internet systems : OTM 2008 Workshops ; OTM Confederated International Workshops and Posters, ADI, AWeSoMe, COMBEK, EI2N, IWSSA, MONET, OnToContent + QSI, ORM, PerSys, RDDS, SEMELS, and SWWS 2008, Monterrey, Mexico, November 9-14, 2008. Proceedings

This volume constitutes the refereed proceedings of 13 international workshops held as part of OTM 2008 in Monterrey, Mexico, in November 2008.The 106 revised full papers presented were carefully reviewed and selected from a total of 171 submissions to the workshops. The volume starts with 19 additional revised poster papers of the OTM 2008 main conferences CoopIS and ODBASE. Topics of the workshop papers are ambient data integration (ADI 2008), agents and web services merging in distributed environment (AWeSoMe 2008), community-based evolution of knowledge-intensive systems (COMBEK 2008), enterprise integration, interoperability and networking (EI2N 2008), system/software architectures .

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On the Move to Meaningful Internet Systems : OTM 2008 ; OTM 2008 Confederated International Conferences, CoopIS, DOA, GADA, IS, and ODBASE 2008, Monterrey, Mexico, November 9-14, 2008, Proceedings, Part II

This two-volume set LNCS 5331/5332 constitutes the refereed proceedings of the five confederated international conferences on Cooperative Information Systems (CoopIS 2008), Distributed Objects and Applications (DOA 2008), Grid computing, high performAnce and Distributed Applications (GADA 2008), Information Security (IS 2008), and Ontologies, Databases and Applications of Semantics (ODBASE 2008), held as OTM 2008 in Monterrey, Mexico, in November 2008.

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On the move to meaningful internet systems : OTM 2008 ; OTM 2008 Confederated International Conferences, CoopIS, DOA, GADA, IS, and ODBASE 2008, Monterrey, Mexico, November 9-14, 2008, Proceedings, Part I

This two-volume set LNCS 5331/5332 constitutes the refereed proceedings of the five confederated international conferences on Cooperative Information Systems (CoopIS 2008), Distributed Objects and Applications (DOA 2008), Grid computing, high performAnce and Distributed Applications (GADA 2008), Information Security (IS 2008), and Ontologies, Databases and Applications of Semantics (ODBASE 2008), held as OTM 2008 in Monterrey, Mexico, in November 2008.

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