الصفحة 1
الصفحة 1
Multiple pregnancy
Multiple pregnancy affects 0.9-3.1% of births worldwide. Prevalence rates vary significantly due to differences in dizygotic twinning rates and use of assisted reproduction. Both maternal and fetal/neonatal complications are more common in multiple compared to singleton pregnancies, and there are specific problems for the fetuses related to monochorionicity. Multiple pregnancies require specialised and individualised care. Complicated multiple pregnancies should be managed in a tertiary care centre where there is additional expertise, such as the laser ablation needed to treat monochorionic monozygotic pregnancies with conjoined circulations. Cornerstones of management in pregnancy are the need for accurate fetal measurement to optimise dating of gestational age, and documentation of chorionicity. High-level ultrasound expertise is needed. The mothers need frequent assessment to detect hypertension and anemia, and early identification and management of preterm labour.
Model Based Inference in the Life Sciences : A Primer on Evidence
The abstract concept of "information" can be quantified and this has led to many important advances in the analysis of data in the empirical sciences. This text focuses on a science philosophy based on "multiple working hypotheses" and statistical models to represent them. The fundamental science question relates to the empirical evidence for hypotheses in this set—a formal strength of evidence. Kullback-Leibler information is the information lost when a model is used to approximate full reality. Hirotugu Akaike found a link between K-L information (a cornerstone of information theory) and the maximized log-likelihood (a cornerstone of mathematical statistics). This combination has become the basis for a new paradigm in model based inference. The text advocates formal inference from all the hypotheses/models in the a priori set—multimodel inference.
Il cielo sopra Roma : I luoghi dell’astronomia = The sky above Rome : The places of astronomy
Astronomy in Rome has always been there, but a little hidden: it was in the palaces, in the churches or, better, above the churches, speculas scattered along a path that few know by now. Intrigued and frightened, the Romans witnessed the burning of Giordano Bruno in a familiar corner of Campo de 'Fiori, but they probably didn't quite understand what guilt he was accused of. They certainly did not think that he was a philosopher and a scientist who had tried to imagine what the world was like.
Geometry for Computer Graphics : Formulae, Examples and Proofs
Geometry is the cornerstone of computer graphics and computer animation, and provides the framework and tools for solving problems in two and three dimensions. This may be in the form of describing simple shapes such as a circle, ellipse, or parabola, or complex problems such as rotating 3D objects about an arbitrary axis. Geometry for Computer Graphics draws together a wide variety of geometric information that will provide a sourcebook of facts, examples, and proofs for students, academics, researchers, and professional practitioners.
Essential Topology
Taking a direct route, Essential Topology brings the most important aspects of modern topology within reach of a second-year undergraduate student. Based on courses given at the University of Wales Swansea, it begins with a discussion of continuity and, by way of many examples, leads to the celebrated ""Hairy Ball theorem"" and on to homotopy and homology: the cornerstones of contemporary algebraic topology. While containing all the key results of basic topology, Essential Topology never allows itself to get mired in details. Instead, the focus throughout is on providing interesting examples that clarify the ideas and motivate the student, reflecting the fact that these are often the key examples behind current research.
Embedded finance : When payments become an experience
In Embedded Finance: When Payments Become An Experience, veteran growth strategists, entrepreneurs, and fintech disruptors Scarlett Sieber and Sophie Guibaud deliver a thought-provoking and page-turning discussion on the most impactful and exciting trend of fintech yet: embedded finance. In the book, you’ll explore the past, present, and future of fintech, from how embedded finance is being leveraged today by industry heavyweights like Google and Amazon to supercharge their customers’ experience to the offerings of smaller, niche players who stand poised to dominate their own corners of the market as their answer unmet customers’ needs.
Educating in the Arts : The Asian Experience: Twenty-Four Essays
Written by leaders in a wide range of creative fields and from all corners of the Asian region, this collection of essays presents arts and education programs which reflect traditional and contemporary practices. The volume brings together researchers, practitioners, educators, children and young people with shared interests in the arts and activities that cross disciplinary divisions and aims to encourage the use of the arts in developing international understanding, celebrating cultural diversity, building cultural bridges and creating cross-cultural dialogue throughout the Asian region.
Design and implementation of an array of patch antenna
Wireless technology is one of the main areas of research in global communication systems today and the study of communication systems is incomplete without an understanding of the process and manufacture of antennas. This was the main reason for choosing this project to focus on this area. This paper presents the design and implementation of an antenna array consisting of 4 patch antenna elements that work on 2.4GHz frequency,the substrate FR4, It was analyzed using HFSS (High Frequency Simulator Structure). In order to achieve a gain of 7 db, and a reflection coefficient of s11 of -10db Then the board was printed And he made measurements in the laboratory on the spectrum analyzer and the kit for the antennas As a result of the measurements, we obtained the antenna gain, the antenna radiation pattern, and the s11
Conceptual Modelling in Information Systems Engineering
Conceptual modeling has always been one of the cornerstones for information systems engineering as it describes the general knowledge of the system in the so-called conceptual schema.It contiant data modeling, goal-oriented modeling, agent-oriented modeling, and process-oriented modeling. Overall, the contributions reflect the most important developments and application areas of conceptual modeling in recent years, and they also pinpoint trends in conceptual modeling for the next decade.
Computational Cognitive Modeling and Linguistic Theory
This book introduces a general framework that allows natural language researchers to enhance existing competence theories with fully specified performance and processing components. Gradually developing increasingly complex and cognitively realistic competence-performance models, it provides running code for these models and shows how to fit them to real-time experimental data. This computational cognitive modeling approach opens up exciting new directions for research in formal semantics, and linguistics more generally, and offers new ways of (re)connecting semantics and the broader field of cognitive science.
Code : The Hidden Language of Computer Hardware and Software ; 2nd ed
The classic guide to how computers work, updated with new chapters and interactive graphics Computers are everywhere --- most obviously in our laptops and smartphones, but also our cars, televisions, microwave ovens, alarm clocks, robot vacuum cleaners, and other smart appliances. Have you ever wondered what goes on inside these devices to make our lives easier but occasionally more infuriating? Explores more deeply the bit-by-bit, gate-by-gate construction of the heart of every smart device ― the central processing unit that combines the simplest of basic operations to perform the most complex of feats. Along with new chapters, Petzold created a new website, CodeHiddenLanguage.com, that uses animated interactive graphics to make computers even easier to comprehend.
Children and the Dark Side of Human Experience : Confronting Global Realities and Rethinking Child Development
Synthesizing insights from psychology and philosophy with his own wide-ranging, first-hand experiences around the world, Dr. James Garbarino takes readers on a personalized journey into the dark side of human experience as it is lived by children. In these highly readable pages, Dr. Garbarino intertwines a discussion of children’s material and spiritual needs with a detailed examination of the clinical knowledge and experiential wisdom required to understand and meet complex developmental needs. Fusing anecdotal observations, empirical evidence, and an ecological perspective, he reveals a path to ensuring the fundamental human rights of all children: the right to safety, to equality, to economic parity, and to a meaningful life.
C*-algebras and Elliptic Theory
This volume contains the proceedings of the conference on "C*-algebras and Elliptic Theory" held in Bedlewo, Poland, in February 2004. It consists of original research papers and expository articles focussing on index theory and topology of manifolds.The collection offers a cross-section of significant recent advances in several fields, the main subject being K-theory (of C*-algebras, equivariant K-theory). A number of papers is related to the index theory of pseudodifferential operators on singular manifolds (with boundaries, corners) or open manifolds. Further topics are Hopf cyclic cohomology, geometry of foliations, residue theory, Fredholm pairs and others.
Arthropod Diversity and Conservation
Despite their enormous bulk and complexity of architecture, plants make up only around a quarter of a million of the 8 million or so species on Earth. The major components of biodiversity, instead, are the smaller, largely unseen, silent majority of invertebrates – most of which are arthropods. Vertebrates, a mere blip on the biotic horizon, are elevated in importance in the bigger scheme of things only by the human psyche. This collection of more than 30 peer-reviewed papers focuses on the diversity and conservation of arthropods, whose species inhabit virtually every recess and plane – and feature somewhere in virtually every food web – on the planet. Highlighting issues ranging from large-scale disturbance to local management, and from spatial heterogeneity to temporal patterns, these papers reflect some of the most exciting new research taking place today – and in some of the most biodiverse corners of the planet.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
Architecture and the modern hospital : Nosokomeion to Hygeia
Explores the rapid evolution of hospital design in the twentieth century, analysing the ways in which architects and other specialists reimagined the modern hospital. It examines how the vast expansion of medical institutions over the course of the century was enabled by new approaches to architectural design and it highlights the emerging political conviction that physical health would become the cornerstone of human welfare.
Architectural Terra Cotta : Design concepts, techniques and applications
Examines the evolution of terra cotta and prepares architects and builders to make new, creative uses of the timeless material. Terra cotta is among the oldest of manufactured building products, yet it has once again become a material of choice in contemporary façade design. From the walls of Babylon to high performance rainscreens, terra cotta claddings have repeatedly proven to be technically superior and aesthetically triumphant. Understanding the evolution of terra cotta prepares architects to add new, creative chapters to a rich history.
Antibiotic pharmacokinetic : Pharmacodynamic considerations in the critically Ill
Provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU. Early, appropriate application of antibiotic therapy remains a cornerstone of effective management. However, this is challenging in the critical care environment, given the significant changes in patient physiology and organ function frequently encountered. Being cognisant of these factors, prescribers need to consider modified dosing regimens, not only to ensure adequate drug exposure, and therefore the greatest chance of clinical cure, but also to avoid encouraging drug resistance.
Anaesthesia, pain, intensive care and emergency medicine A.P.I.C.E. ; Proceedings of the 22nd Postgraduate Course in Critical Care Medicine Venice-Mestre, Italy — November 9–11, 2007
Improving standards of care is a real challenge in Intensive Care Medicine. Bettering clinical performance, patient safety, risk management and audit represents the cornerstone for raising the quality of care in ICU patients.
