الصفحة 1
الصفحة 1
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Drug target selection and validation

Focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.

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ITI treatment guide ; Vol.11 : Digital workflows in implant dentistry

Addressing the technology and tools necessary to incorporate DDT into a traditional workflow, along with the clinical steps required for data acquisition, such as CBCT imaging and intraoral, extraoral, and facial scanning. The software tools needed to interpret the digital data are presented, and instructions are given on how to integrate data sets to virtually reconstruct the patient s orofacial anatomy. In addition, a series of 13 clinical cases illustrate digital technologies applied to oral implantology.

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Architectural scale models in the digital age : Design, representation and manufacturing

Complex geometric forms generated using virtual media can be tested and validated only by means of physical models, which also make it possible to assess their practical application. The complexity of contemporary architectural design requires the mastery of new methods of producing scale models, which opens a new chapter in the field of modeling, and is the focus of this book. Along with the traditional methods that provide the basis for modeling, this book presents the principles of digital NURBS modeling, parametric modeling, digital modeling support, and model creation, complete with a number of tutorials, practical advice and examples found in architectural practice today.

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Architectural drafting and design

Ideal book for all architectural drafters and CAD operators, whether beginning, intermediate, or advanced. An important feature of this best--seller is its step--by--step instructions for the design and layout of each type of drawing associated with a complete set of architectural plans, with projects that can be completed using either CAD or manual drawing methods. The basics of residential design, commercial drafting, basic materials used for construction, common construction methods, and drawings typically associated with commercial construction are all covered in this comprehensive book, which is written to meet the most recent editions of IRC and IBC. Readers will be introduced to the various types of projects that a designer or architect is likely to complete during the actual design process and will gain the knowledge needed to complete the drawings required by most municipalities to obtain a building permit for a single--family residence.

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A Studio Guide to Interior Design

Provides a foundation of the analog and digital design processes in interior architecture, interior design and associated disciplines, such as architecture. Throughout the book there are key references to drawing, digital practice, author illustrated diagrams and design precedents. Ancillaries include web-based videos taking the reader through digital graphic principles and planned exercises for use in the classroom environment.

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