الصفحة 1
الصفحة 1
Ocular Transporters in Ophthalmic Diseases and Drug Delivery
This exceptionally important new work represents recent discoveries and advancements in the study of ocular transporters and their roles in ocular physiology, pathology, and drug delivery. Transporters are found on the membranes of cells and play a key role in transmitting signals between cells. In Ocular Transporters in Ophthalmic Diseases and Drug Delivery, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium, and the transport of nutrients across the retinal pigment epithelium. It also provides an in-depth look at how mutations or dysfunction of specific transporters can contribute to various disorders in the eye, including blindness, and provides readers with potential targets and strategies to allow safe passage of therapeutic drugs into the eye.
Ocular Angiogenesis : Diseases, Mechanisms, and Therapeutics
Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches. Comprehensive and multidisciplinary, Ocular Angiogenesis: Diseases, Mechanisms, and Therapeutics offers a novel view of the clinical features of pathological angiogenesis in the eye, the molecular and environmental switches that govern vessel growth, and the tremendous opportunities for and progress made in the development of new therapeutics.
Nutraceuticals and bone health
Here is an informative volume on the importance of nutraceuticals and herbal remedies for bone health. It explains the probable mechanisms of nutraceuticals for the prevention, treatment, and management of bone-related diseases as well as their curable effects on bone injuries. The volume covers the progression and development of bones, which is a multifaceted process that requires an endless and ample supply of nutrients, such as calcium, phosphorus, potassium, protein, vitamin D, magnesium, and fluoride. The book delves into the beneficial effects of nutraceuticals on overall bone health and for the treatment of bone disorders such as osteoporosis, bone fractures, scoliosis and related complications, rheumatoid arthritis, Paget’s disease, bursitis, gout, and carpal tunnel syndrome. It also addresses the use of nutraceuticals for inflammatory deformities and rickets.
Nucleation and Atmospheric Aerosols ; 17th International Conference, Galway, Ireland, 2007
Atmospheric particles are ubiquitous in the atmosphere: they form the seeds for cloud droplets and they form haze layers, blocking out incoming radiation and contributing to a partial cooling of our climate. They also contribute to poor air quality and health impacts. This book brings together the leading experts from the nucleation and atmospheric aerosols research communities to present the current state-of-the-art knowledge in these related fields.
NASAs Scientist-Astronauts
Mounting pressure in the early 1960s from the National Academy of Sciences (NAS) to study ways of expanding the role of astronauts to conduct science on future space missions led to NASA’s conclusion that flying scientifically trained crewmembers would generate greater returns from each mission. NASA and industry studies continued investigating possibilities that could lead to the eventual creation of the first space stations using surplus Apollo hardware, through the Apollo Applications Programme (AAP).
Multiple Stressors : A Challenge for the Future
This book publishes the Proceedings of the NATO Advanced Research Workshop on Multipollution Exposure and Risk Assessment, Ecotoxiclogical risk from multiple stressors covers any situation where org- isms are exposed to a combination of environmental stressors. These include physical and chemical pollutants as well as other stressors such as parasites and environmental impact (e. g. , climate change or habitat loss). The combi- tion of stressors can result in increased risk to organisms (either additive or synergistic effects) or decreased effects (protective or antagonistic effects). The multiple stressor challenge is an international, multi-disciplinary problem requiring an international, multi-disciplinary approach. The c- rent approach to multiple stressors is to examine one stressor at a time and assume additivity.
Moral Education : Beyond the Teaching of Right and Wrong
This volume is unique in providing a comprehensive discussion of moral education in the light of a range of ethical theories. In a balanced, thoughtful and penetrating account, all of these are shown to have a contribution to make to our moral understanding, and hence to moral education, even if none provides a definitive criterion of moral conduct. Though divine command is rejected as a source of moral justification, the possible contribution of some religious traditions to moral education is sympathetically considered. Fashionable relativism and recent moves towards inculcatory authoritarianism are both firmly rejected. The argument is philosophically rigorous throughout. Contemporary issues addressed include the links between personal morality and citizenship, including world citizenship, family values and sexual morality.
Molecular Techniques in the Microbial Ecology of Fermented Foods
Molecular Methods and Microbial Ecology of Fermented Foods presents the latest findings in microbial ecology as determined by the application of molecular methods, reports the most recent advances in the field, and offers details on primers and protocols most suitable for studying specific food ecosystems. It provides analytical details and suggestions useful in research, as well as evaluation of the criticism of using novel approaches in food fermentation microbiology. This book also discusses new insights drawn from the use of bio-molecular techniques in the microbial ecology of fermented foods.
Molecular Genetics of Recombination
Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial during DNA replication in vegetatively growing cells.
Mechanisms of the Glaucomas : Disease Processes and Therapeutic Modalities
In this book leaders in the various fields of glaucoma review our current understanding of glaucoma from epidemiology and genetics through molecular, cellular and tissue responses to the mechanisms of the glaucomas and the mechanisms by which we manage them.
Intelligent data engineering and automated Learning - IDEAL 2008 ; 9th International Conference Daejeon, South Korea, November 2-5, 2008 Proceedings
This book constitutes the refereed proceedings of the 9th International Conference on Intelligent Data Engineering and Automated Learning, IDEAL 2008, held in Daejeon, Korea, in November 2008.The 56 revised full papers presented together with 10 invited papers were carefully reviewed and selected from numerous submissions for inclusion in the book. The papers are organized in topical sections on learning and information processing, data mining and information management, bioinformatics and neuroinformatics, agents and distributed systems, as well as financial engineering and modeling.
Information security and privacy ; Vol. 3574 : 10th Australasian Conference, ACISP 2005, Brisbane, Australia, July 4-6, 2005, Proceedings
Constitutes the refereed proceedings of the 10th Australasian Conference on Information Security and Privacy, ACISP 2005, held in Brisbane, Australia in July 2005. The papers are organized in topical sections on network security, cryptanalysis, group communication, elliptic curve cryptography, mobile security, side channel attacks, and more.
Information context : Nature, impact, and role ; 5th International conference on Conceptions of Library and Information Sciences, CoLIS 2005, Glasgow, UK, June 4-8, 2005 Proceedings
.CoLIS examinesthehistorical,theoretical,empiricalandtechnicalissuesrelatingtoour understanding and use of information, promoting an interdisciplinary approach to research. CoLIS seeks to provide a broad platform for the examination of context as it relates to our theoretical, empirical and technical development of information-centered disciplines. The theme for CoLIS 5 was the nature, impact and role of context within information-centered research. Context is a complex, dynamic and multi- - mensional concept that in?uences both humans and machines: how they behave individually and how they interact with each other. In CoLIS 5 we took an interdisciplinary approach to the issue of context to help us understand and the theoretical approaches to modelling and understanding context, incorporate contextual reasoning within technology, and develop a shared framework for promoting the exploration of context.
Human microbiome : Clinical implications and therapeutic interventions
The human microbiome refers to the complete microorganisms inhabiting the human body sites including skin, ear, nose, oral cavity, the genital, gastrointestinal and respiratory tracts, and body fluids such as breast milk, saliva, and urine. It is a significant and essential organ recognized for the body and has an established involvement in the host wellbeing, in terms of nutritional requirements and immunomodulation. Talks about how alteration and imbalance in the same can have clinical implications associated with a multitude of gastrointestinal, lifestyle-associated, and neurodegenerative disorders. How the proliferation of specific groups of bacteria and their metabolic activities, as a result of intestinal dysbiosis leads to the 'leaky gut' condition thereby influences brain activity via the bidirectional gut-brain axis. It also coves the importance of microbial seeding and how it can be influenced by the mode of delivery, nutrition, and medication. This book also provides various therapeutic interventions such as the establishment of stool banks and Faecal microbiota transplantation (FMT) that have recently proved promising in the treatment of ASD, Inflammatory Bowel Disease, and Ulcerative Colitis. This book provides a deeper understanding of the development of the human gut microbiome and the factors driving its dysbiosis. This book is a valuable read for health professionals, medical students, nutritionists, and scientific research communities who are eager to update themselves with recent trends in microbiome research. It will also aid gastroenterologists and nutritionists to make well-informed choices regarding therapeutic regimes.
Herbs for common ailments : How to make and use herbal remedies for home health care
Shows you how to use 56 common herbs to address a wide range of everyday ailments, from burns, wounds, and itchy skin to headaches, congestion, indigestion, strains, bruises, sore throats, coughs, fevers, colic, cramps, and insomnia. She also shows you how to stock a simple first-aid kit with safe, effective herbal remedies.
Hebbian Learning and Negative Feedback Networks
This book is the outcome of a decade’s research into a speci?c architecture and associated learning mechanism for an arti?cial neural network: the - chitecture involves negative feedback and the learning mechanism is simple Hebbian learning. The research began with my own thesis at the University of Strathclyde, Scotland, under Professor Douglas McGregor which culminated with me being awarded a PhD in 1995 [52], the title of which was “Negative Feedback as an Organising Principle for Arti?cial Neural Networks”. Naturally enough, having established this theme, when I began to sup- vise PhD students of my own, we continued to develop this concept and this book owes much to the research and theses of these students at the Applied Computational Intelligence Research Unit in the University of Paisley . All of Chapters 3 to 8 deal with single stream arti?cial neural networks.
Handbook of Pharmaceutical Excipients
Recognised as the world’s most authoritative source of information on pharmaceutical excipients. It provides you with a one stop resource when researching an excipient for use. The 400+ monographs are also thoroughly cross referenced and indexed to allow their identification by chemical, non proprietary or trade names. Content include: - Over 420 fully referenced excipient monographs, many including IR, Raman, and NIR spectra / 13 new monographs including several amino acids and hydrated silicon dioxide / 250 existing monographs reviewed / New chapters include excipient selection for orally inhaled and injectable formulations
Foodborne Parasites
Microbiologists are being challenged as foodborne outbreaks are increasingly being observed worldwide. Most of these outbreaks are associated with viral and bacterial pathogens such as Campylobacter, Salmonella, and lately Escherichia coli O157:H7.Foodborne Parasites examines the two major parasite groups that are transmitted via water or foods: the protozoa, which are single celled organisms, and the helminths. The helminths are classified in three sub groups: cestodes (tapeworms), nematodes (round worms), and trematodes (flukes). To better understand their significance, each chapter covers the biology, mechanisms of pathogenesis, epidemiology, treatment, and inactivation of these parasites.
FinFETs and Other Multi-Gate Transistors
FinFETs and Other Multi-Gate Transistors provides a comprehensive description of the physics, technology and circuit applications of multigate field-effect transistors (FETs). It explains the physics and properties of these devices, how they are fabricated and how circuit designers can use them to improve the performances of integrated circuits.
Fare astronomia con piccoli telescopi = Are astronomy with small telescopes
Giant tools are not necessarily required to produce scientifically valid results in the field of astronomy. Even the amateur with a small telescope, with a diameter of only 8-9 cm, can contribute to the science of the sky by making useful observations of the Sun, the Moon, planets, comets, asteroids, double or variable stars, nebulae and star clusters. The manual of M.K. Gainer explains what the minimum equipment is (a small telescope, a computer, a simple digital camera), how to use it, and what are the appropriate techniques to be adopted in the observations. It also offers schemes for interpreting and reducing the collected data, as well as forms to be filled in and sent to international collection centers.
