الصفحة 1
الصفحة 1
Co-enzyme Q10
Coenzyme Q10 is a vitamin like substance that has been found in both microorganisms and plants as well as in animals and humans. In this research we will talk about CoenzymeQ10, it’s biochemical functions and roles in health and diseases such as Parkinson, cardiovascular diseases, diabetes, male fertility, cancers , covid19 and immune functions. Some coQ10 determination methods in foods will be discussed. At the last can we use it as asupplement? Does it have an adverse effects and contraindications? and what are the factors that affect on it’s plasma concentrations ? .
CO-ENZYME Q10
Coenzyme Q10 (CoQ10) is a fat-soluble compound that is synthesized by the body and can be obtained from the diet. Co-Q10 plays a central role in mitochondrial oxidative phosphorylation and the production of adenosine triphosphate (ATP). It also functions as an antioxidant in cell membranes and lipoproteins. Endogenous synthesis and dietary intake provide sufficient C0- Q10 to prevent deficiency in healthy people, although coenzyme Q10 concentrations in tissues decline with age. Oral supplementation of coenzyme Q10 increases coenzyme Q10 concentrations in plasma and lipoproteins. Oral high-dose co- Q10 is usually effective to treat mitochondrial disorders that are caused by mutations in coenzyme Q10 biosynthetic genes.
