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الصفحة 1
Ontology Learning and Population from Text: Algorithms, Evaluation and Applications
Ontology Learning and Population from Text: Algorithms, Evaluation and Applications presents approaches for ontology learning from text and will be relevant for researchers working on text mining, natural language processing, information retrieval, semantic web and ontologies. Containing introductory material and a quantity of related work on the one hand, but also detailed descriptions of algorithms, evaluation procedures etc. on the other, this book is suitable for novices, and experts in the field, as well as lecturers.
Multiscale Problems in the Life Sciences : From Microscopic to Macroscopic
The aim of this volume that presents Lectures given at a joint CIME and Banach Center Summer School, is to offer a broad presentation of a class of updated methods providing a mathematical framework for the development of a hierarchy of models of complex systems in the natural sciences, with a special attention to Biology and Medicine. Mastering complexity implies sharing different tools requiring much higher level of communication between different mathematical and scientific schools, for solving classes of problems of the same nature. Today more than ever, one of the most important challenges derives from the need to bridge parts of a system evolving at different time and space scales, especially with respect to computational affordability. As a result the content has a rather general character; the main role is played by stochastic processes, positive semigroups, asymptotic analysis, kinetic theory, continuum theory and game theory.
Molluscs : From Chemo-ecological Study to Biotechnological Application
Marine molluscs are very promising candidates for a wide range of biotechnological applications. For example, they possess analgesic drugs more potent than morphine and very effective anticancer agents. The present book gives an up-to-date overview of the main classes of bioactive compounds from molluscs, moving from ecological observations, to chemical characterization, to biosynthesis, to large-scale synthesis, and to pharmacological applications. A truly outstanding international panel of experts from all continents provides complete coverage of the most stimulating topics related to molluscs. This knowledge of their history and current studies provides an open door to the future.
Microscale Diagnostic Techniques
Microscale Diagnostic Techniques highlights the most innovative and powerful developments in microscale diagnostics. It provides a resource for scientists and researchers interested in learning about the techniques themselves, including their capabilities and limitations.
Inverse Problems and Imaging : Lectures given at the C.I.M.E. Summer School held in Martina Franca, Italy September 15–21, 2002
Nowadays we are facing numerous and important imaging problems: nondestructive testing of materials, monitoring of industrial processes, enhancement of oil production by efficient reservoir characterization, emerging developments in noninvasive imaging techniques for medical purposes - computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), X-ray and ultrasound tomography, etc. In the CIME Summer School on Imaging (Martina Franca, Italy 2002), leading experts in mathematical techniques and applications presented broad and useful introductions for non-experts and practitioners alike to many aspects of this exciting field. The volume contains part of the above lectures completed and updated by additional contributions on other related topics: a general presentation and introduction (Moscoso), X-ray tomography (Natterer), Electromagnetic imaging (Dorn, Bertete-Aguirre, Papanicolaou), coherent imaging in telecommunications in a multiple input-multiple output setup (Dorn), polarization based optical imaging (Moscoso), topological derivatives used in shape reconstruction related to inverse scattering problems (Carpio, Rapún), Point interactions (Dell’Antonio, Figari, Teta).
Hyperbolic Systems of Balance Laws : Lectures given at the C.I.M.E. Summer School held in Cetraro, Italy, July 14-21, 2003
The present Cime volume includes four lectures by Bressan, Serre, Zumbrun and Williams and an appendix with a Tutorial on Center Manifold Theorem by Bressan. Bressan’s notes start with an extensive review of the theory of hyperbolic conservation laws. Then he introduces the vanishing viscosity approach and explains clearly the building blocks of the theory in particular the crucial role of the decomposition by travelling waves. Serre focuses on existence and stability for discrete shock profiles, he reviews the existence both in the rational and in the irrational cases and gives a concise introduction to the use of spectral methods for stability analysis. Finally the lectures by Williams and Zumbrun deal with the stability of multidimensional fronts.
Handbook of Renal Biopsy Pathology
This practical handbook provides a short, clear and useful guide to interpretation of renal biopsy specimens. It is intended to be useful to pathologists, pathologists-in-training, nephrologists, nephrologists-in-training and medical students.
Guide to Effective Grant Writing : How to Write a Successful NIH Grant Application
Guide to Effective Grant Writing: How to Write a Successful NIH Grant is written to help the 100,000+ post-graduate students and professionals who need to write effective proposals for grants. There is little or no formal teaching about the process of writing grants for NIH, and many grant applications are rejected due to poor writing and weak formulation of ideas. Procuring grant funding is the central key to survival for any academic researcher in the biological sciences; thus, being able to write a proposal that effectively illustrates one's ideas is essential. Covering all aspects of the proposal process, from the most basic questions about form and style to the task of seeking funding, this volume offers clear advice backed up with excellent examples. Included are a number of specimen proposals to help shed light on the important issues surrounding the writing of proposals. The Guide is a clear, straight-forward, and reader-friendly tool.
GDPR and biobanking : Individual rights, Public interest and research regulation across Europe
This book focuses on the discrepancies in biobank research regulations that are among the most significant hurdles to effective research collaboration.
Fundamentals of analytical toxicology : Clinical and forensic ; 2nd ed.
An integrated introduction to the analysis of drugs, poisons, and other foreign compounds in biological and related specimens. Assuming only basic knowledge of analytical chemistry, this invaluable guide helps trainee analytical toxicologists understand the principles and practical skills involved in detecting, identifying, and measuring a broad range of compounds in various biological samples. Clear, easy-to-read chapters provide detailed information on topics including sample collection and preparation, spectrophotometric and luminescence techniques, liquid and gas-liquid chromatography, and mass spectrometry including hyphenated techniques. Focuses on analytical, statistical, and pharmacokinetic principles / Describes basic methodology, including colour tests and immunoassay and enzyme-based assays / Outlines laboratory operations, such as method validation, quality assessment, staff training, and laboratory accreditation / Follows IUPAC nomenclature for chemical names and recommended International Non-proprietary Name (rINN) for drugs and pesticides / Includes discussion of 'designer drugs' (novel pharmaceutical substances NPS)
From Cells to Proteins : Imaging Nature across Dimensions ; Proceedings of the NATO Advanced Study Institute, held in Pisa, Italy, 12-23 September 2004
This book offers updated information on how much information we are able to obtain in the exploration of the inner details of biological specimens in their native structure and composition. And deals with the implementation of laser beam and stage scanning systems incorporating confocal optics or multiphoton microscopy; the advent of new electro-optical detectors with great sensitivity, linearity, and dynamic range; the possibility of 2D fast image enhancement, reconstruction, restoration, analysis and 3D display, and the application of luminescence techniques.
Formal Methods for Hardware Verification ; 6th International School on Formal Methods for the Design of Computer, Communication, and Software Systems, SFM 2006, Bertinoro, Italy, May 22-27, 2006, Advances Lectures
This book presents 8 papers accompanying the lectures of leading researchers given at the 6th edition of the International School on Formal Methods for the Design of Computer, Communication and Software Systems (SFM 2006). SFM 2006 was devoted to formal techniques for hardware verification and covers several aspects of the hardware design process, including hardware design languages and simulation, property specification formalisms, automatic test pattern generation, symbolic trajectory evaluation, and more.
Flow cytometry in hematopathology : A visual approach to data analysis and interpretation
Although instrumentation and laboratory techniques for flow cytometry (FCM) immunophenotyping of hematopoietic malignancies are well documented, there is relatively little information on how best to perform data analysis, a critical step in FCM testing. In Flow Cytometry in Hematopathology: A Visual Approach to Data Analysis and Interpretation, three physicians highly experienced in laboratory hematopathology and FCM offer a unique systematic approach to FCM data analysis and interpretation based on the visual inspection of dual parameter FCM graphics. This step-by-step approach to optimal FCM data analysis is demonstrated by means of numerous FCM graphics derived from actual well-documented clinical cases.The focus of the additional material is on the TCR-Vb eight-tube kit which has greatly facilitated the evaluation mature T-cell disorders, and on the DNA dye DRAQ5 for improved grading of malignant lymphoma. The authors also include notes on "tricks of the trade" and pitfalls to avoid. The discussion, covering leukemias, lymphomas, and other conditions, moves from simple to complex specimens, with an emphasis on visual pattern analysis.
Farmacognosia applicata : Controllo di qualità delle droghe vegetali
Il processo di identificazione è per una droga vegetale di enorme importanza ai fini dell'efficacia e sicurezza della stessa. Infatti la risposta terapeutica e gli effetti indesiderati sono fortemente condizionati dall'identificazione della droga e dalla presenza di contaminanti botanici. Il testo si compone di due parti; la prima sintetizza gli aspetti diagnostici che indirizzano verso il riconoscimento della droga vegetale, mentre la seconda descrive gli aspetti macro- e microscopici della droga ed i saggi chimici e farmacologici che consentono con certezza l’identificazione della stessa. Infine, l’ultima parte riporta alcuni esempi di cromatogrammi e di tracciati di organi isolati.
Experiment and Natural Philosophy in Seventeenth-Century Tuscany : The History of the Accademia del Cimento
This work is to counter historiographies that search for the origins of modern science within the experimental practices of Europe’s first scientific institutions, such as the Cimento. It proposes that we should look beyond the experimental rhetoric found in published works, to find that the Cimento academicians were participants in a culture of natural philosophical theorising that existed throughout Europe.
Excimer Laser Technology
This comprehensive survey on Excimer Lasers investigates the current range of the technology, applications and devices of this commonly used laser source, as well as the future of new technologies, such as F2 laser technology. Additional chapters on optics, devices and laser systems complete this compact handbook. A must read for laser technology students, process application researchers, engineers or anyone interested in excimer laser technology. An effective and understandable introduction to the current and future status of excimer laser technology.
Enumerative Invariants in Algebraic Geometry and String Theory : Lectures given at the C.I.M.E. Summer School held in Cetraro, Italy June 6–11, 2005
Starting in the middle of the 80s, there has been a growing and fruitful interaction between algebraic geometry and certain areas of theoretical high-energy physics, especially the various versions of string theory. Physical heuristics have provided inspiration for new mathematical definitions (such as that of Gromov-Witten invariants) leading in turn to the solution of problems in enumerative geometry. Conversely, the availability of mathematically rigorous definitions and theorems has benefited the physics research by providing the required evidence in fields where experimental testing seems problematic. The aim of this volume, a result of the CIME Summer School held in Cetraro, Italy, in 2005, is to cover part of the most recent and interesting findings in this subject.
Electron Tomography : Methods for Three-Dimensional Visualization of Structures in the Cell
Electron tomography has become a standard technique with applications in cell biology, structural biology, and materials science. This definitive work provides a comprehensive treatment of the mathematical background and working methods of three-dimensional reconstruction from tilt series, with special emphasis on the problems presented by limitations of data collection in the transmission electron microscope. In addition to chapters that are applicable to 3D reconstruction in all fields of science, such as radiological imaging in medicine and electron tomography in materials science, Electron Tomography also focuses on specimen preparation and imaging unique to biological electron microscopy.
Ecosystem Organization of a Complex Landscape : Long-Term Research in the Bornhöved Lake District, Germany
Presents the major findings of a 12-year ecological study of the Bornhöved Lake District, situated some 30 km south of Kiel. Historically speaking, the present research scheme, like comparable long-term ecosystem studies at Göttingen, Bayreuth, München, and Berchtesgaden, has been conceived as the core of a comprehensive ecological surveillance system for Germany (Ellenberg et al. 1978). Comprising three interrelated components, namely an ecological monitoring network, comparative ecosystem research, and an environmental specimen bank, this system is intended to promote both ecological science and planning and policy. In this connection the geo- and bioscientifically based ecosystem research aims at understanding the structure and functions of systems, the natural equilibrium and stress tolerance of singular components and the entire system against changes and disturbances from within and from outside, and the relationships between diversity, productivity, and stability. Thus, ecosystem research forms the indispensable basis for the rational analysis of the comprehensive data sets made available by ecological monitoring networks and for the adequate selection of plant, animal, and soil specimens for environmental specimen banking purposes.
Drugs of abuse : Body fluid testing
The authors discuss the various body fluid specimens suitable for testing for illicit drugs describe the structural and manufacturing aspects of on-site testing devices based on lateral flow immunoassay, and detail the pitfalls sometimes encountered when using these specimens. They also discuss in detail the problem of sample adulteration and its detection. Political, social, and legal issues are also considered in articles on privacy, the use of drug testing in courts, and the problem of sample adulteration.
