الصفحة 1
الصفحة 1
Modulation of host gene expression and innate immunity by viruses
This book is reference on a relatively young area of research in which virology, cellular biology and molecular pathogenesis govern the principles of coinvestigation. Infection of a naïve (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity). The outcome of this interaction is influenced by the genes of the virus as well as the genes of the host. Interestingly, different viruses do it in different ways. Not only is there a plethora of mechanisms used by the invading organisms, but the host has also evolved a great variety of redundant and robust countermeasures. This interplay of host and virus represents one of the most significant frontiers in biology today. A clearer understanding of the mechanisms involved will arm us with better strategies to deal with viruses, including emerging pathogens and potential bioterrorism agents. This book is sure to benefit students, scientists, and physicians working in the areas of virology, immunology, microbiology, and infectious diseases.
Microorganisms and Bioterrorism
The purpose of this book is to bring together, in a single volume, the most up-to-date information concerning microbes with potential as bioterrorist weapons. The primary audience includes microbiologists, including bacteriologists, virologists and mycologists, in academia, government laboratories and research institutes at the forefront of studies concerning microbes which have potential as bioterrorist weapons, public health physicians and researchers and scientists who must be trained to deal with bioterrorist attacks as well as laboratory investigators who must identify and characterize these microorganisms from the environment and from possibly infected patients.
Handbook of Bioterrorism and Disaster Medicine
This comprehensive volume, written by experts in the field, is the essential portable handbook on bioterrorism and disaster medicine. The volume covers all pertinent topics with meticulous organization and includes an abundance of invaluable web-based resources. Written as both a practical and clinical guide to various types of disasters, it includes planning and response procedures to help mitigate the impact of disasters on affected individuals and communities. Designed to be used in the field, all the essential aspects are included: public health, bioterror agents, chemical warfare, radioactive agents, manmade disasters, natural disasters, humanitarian disasters, infectious and tropical diseases, and basics of emergency medicine. Handbook of Bioterrorism and Disaster Medicine is the ideal tool for researchers, first responders, medical students, physicians, and other healthcare providers who work in the field.
Foodborne Microbial Pathogens : Mechanisms and Pathogenesis
The author presents up-to-date information on molecular and cellular mechanism of several major foodborne microbial pathogens, including select agents for bioterrorism, virulence genes and their regulation in the host or the food environment, pathogenicity testing models, clinical symptoms, and prevention and control strategies. In order to understand the disease process, one must have certain understanding about the role of the immune system. Thus this book also covers the host parasite interaction to a level where the readers will have a better appreciation for the disease mechanism.
Filoviruses : A Compendium of 40 Years of Epidemiological, Clinical, and Laboratory Studies
This book summarizes in detail the contemporary knowledge of filoviruses and diseases they cause. Almost the entirety of the open literature on filoviruses, covering all major scientific and clinical fields, is referenced and summarized in this text, including most of the conference abstracts, book chapters, dissertations, government reports, patents, theses, and journal publications in many languages.
Ethical and Philosophical Consideration of the Dual-Use Dilemma in the Biological Sciences
This book examines the kinds of life-science experiments that give rise to the dual-use dilemma and provides philosophical analysis of the ethical issues and policy options surrounding dual-use research. this is the first book-length treatment of the topic by professional ethicists. It also challenges, and offers an alternative perspective to, the hugely influential U.S. National Research Council position on the dual-use dilemma.
Crop Biosecurity : Assuring our Global Food Supply
Prevention and preparedness are the two basic approaches to maximize food security against any sort of tampering, whether natural, inadvertent or intentional. The NATO funded project “Tools for crop biosecurity” was designed to strengthen the cooperation among U.S., Europe and Israel in the field of crop biosecurity and to generate awareness on how the psychological, economic and cultural consequences of crop bioterrorism, especially attacks on soft targets such as crop seeds, could have a disproportionate adverse effect on Mediterranean agriculture and, more generally, on society.This book illustrates the achievements of the project originated from the workshops organized during the project itself taking in consideration main microbiological threads posed to crops, the tools to recognize and to control them, the needs for international cooperation and research funds to create networks which can face emerging risks for agriculture.
Clinical Guide to Bioweapons and Chemical Agents
Clinical Guide to Bioweapons and Chemical Agents is a quick reference for the busy clinician, to assist in the new public health response to the threats from bioterrorism and other public health disease.
Bioterrorism and Infectious Agents : A New Dilemma for the 21st Century
Since the terrorist attack on the United States on September 11, 2001 and subsequent cases of anthrax in Florida and New York City, attention has been focused on the threat of b- logical warfare and bioterrorism. Biological warfare agents are de?ned as “living org- isms, whatever their nature, or infected material derived from them, which are used for h- tile purposes and intended to cause disease or death in man, animals and plants, and depend for their efforts on the ability to multiply in person, animal or plant attacked.” Biological warfare agents may be well suited for bioterrorism to create havoc and terror in a civilian population, because they are cheap and easy to obtain and dispense. Infectious or contagious diseases have played a major part in the history of warfare – deliberately or inadvertently – in restricting or assisting invading armies over the centuries. In 1346, the Tartars catapulted plaque-infected bodies into Kaffa in the Crimea to end a 3-year siege. Blankets contaminated with smallpox to infect North American Indians were used by British forces in the 18th century. More recently, the Japanese released ?eas infected with plaque in Chinese cities in the 1930s and 1940s. Biological research programs for both offensive and defensive strategies have been developed by the United States, Britain, the former Soviet Union, and Canada; several other nations are thought to have such programs.
Biological, chemical, and radiological Terrorism : Emergency preparedness and response for the primary care physician
This book provides sought-after guidance to primary care physicians on preparing for and responding to terrorist events. Chapters offer a fundamental understanding of the epidemiology and relevant clinical aspects of diseases caused by biological agents (anthrax, plague, smallpox, botulism, tularemia, and hemorrhagic viruses), chemical agents (nerve and blister), and radiological agents. The text details how to detect terrorist-caused illness as early as possible, how to provide defensive or preventive therapy, and how to triage and treat ill patients. Emphasis is placed on addressing both the physical and psychological impact on patients and providers.
