الصفحة 1
الصفحة 1
Novel mouse model for future autism research
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by a deficit in social behaviors and nonverbal interactions such as reduced eye contact, facial expression, and body gestures in the first 3 years of life. It is not a single disorder, and it is broadly considered to be a multi-factorial disorder resulting from genetic and non-genetic risk factors and their interaction. Genetic studies of ASD have identified mutations that interfere with typical neurodevelopment in utero through childhood. These complexes of genes have been involved in synaptogenesis and axon motility. Recent developments in neuroimaging studies have provided many important insights into the pathological changes that occur in the brain of patients with ASD in vivo. Especially, the role of amygdala, a major component of the limbic system and the affective loop of the cortico-striatothalamo-cortical circuit, in cognition and ASD has been proved in numerous neuropathological and neuroimaging studies.
Nonparametric Functional Data Analysis : Theory and Practice
Modern apparatuses allow us to collect samples of functional data, mainly curves but also images. On the other hand, nonparametric statistics produces useful tools for standard data exploration. This book links these two fields of modern statistics by explaining how functional data can be studied through parameter-free statistical ideas. This book starts from theoretical foundations including functional nonparametric modeling, description of the mathematical framework, construction of the statistical methods, and statements of their asymptotic behaviors. It proceeds to computational issues including R and S-PLUS routines. Several functional datasets in chemometrics, econometrics, and pattern recognition are used to emphasize the wide scope of nonparametric functional data analysis in applied sciences. The companion Web site includes R and S-PLUS routines, command lines for reproducing examples presented in the book, and the functional datasets. Rather than set application against theory, this book is really an interface of these two features of statistics. A special effort has been made in writing this book to accommodate several levels of reading.
New Directions in Human Information Behavior
The book presents chapters by an interdisciplinary range of scholars who show new directions that often challenge the established views and paradigms of information behavior studies. Beginning with an evolutionary framework, the book examines information behaviors over various epochs of human existence from the Palaeolithic Era and within pre-literate societies, to contemporary behaviors by 21st century humans. Drawing upon social and psychological science theories the book presents a more integrated and holistic approach to the understanding of information behaviors that include multitasking and non-linear longitudinal processes, individuals’ information ground, information practices and information sharing, digital behaviors and human information organizing behaviors. The final chapter of the book integrates these new approaches and presents an overview of the key trends, theories and models for further research.
Neuroblastoma
Neuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predicted to a large extent by the stage of disease and the age at diagnosis, an in-depth understanding of its clinico-pathological behavior, now greatly aided by sophisticated molecular genetic profiling, will improve diagnostic precision and refine risk-based therapies. Comprehensive international efforts have advanced our understanding of tumor biology and improved the clinical management of children with neuroblastoma. This book reviews our current understanding of the genes and biological pathways that contribute to neuroblastoma pathogenesis, modern risk-based treatment approaches for these patients, and recent advances in biologically based therapy. It provides a concise up-to-date reference for practitioners, students, and researchers.
Neurobiology of Exceptionality
Nurture or nature? Biology or environment? Why are some people intelligent, or personable, or creative and others obtuse, or shy, or unimaginative? Although each human being is a unique mixture of positive and negative traits and behaviors, the question remains: What is the neurobiological basis for each individual’s makeup? For example, why does one person suffer from a disorder (e.g., ADHD, autism, mental retardation) and another lives free of maladies?
Neural Preprocessing and Control of Reactive Walking Machines: Towards Versatile Artificial Perception-Action Systems
This book presents biologically inspired walking machines interacting with their physical environment. It describes how the designs of the morphology and the behavior control of walking machines can benefit from biological studies. The purpose of this book is to develop a modular structure of neural control generating different reactive behaviors of the physical walking machines, to analyze the neural mechanisms underlying the reactive behaviors, and to demonstrate the sensor fusion technique leading to smooth switching between appropriate behaviors, like obstacle avoidance and sound tropism.
Mobilizing Adults for Positive Youth Development : Strategies for Closing the Gap between Beliefs and Behaviors
"In today's fast-paced, often-dehumanizing world, increasing positive adult involvement and influence is particularly vital. To further that goal, Mobilizing Adults for Positive Youth Development: Strategies for Closing the Gap between Beliefs and Behaviors brings together, in one concise volume, the advice and expertise of leading scholars dedicated to affecting positive youth development. Taken together, the chapters in this book provide a multifaceted, multidisciplinary blueprint for social change." "Mobilizing Adults for Positive Youth Development: Strategies for Closing the Gap between Beliefs and Behaviors is a must-have volume for both practitioners and researchers - in fact, for anyone interested and involved in working toward achieving positive youth development.
Mobile and Wireless Communications Networks ; IFIP TC6 / WG6.8 Conference on Mobile and Wireless Communication Networks (MWCN 2004) October 25-27, 2004 Paris, France
Mobile Ad hoc NETworks (MANETs) has attracted great research interest in recent years. A Mobile Ad Hoc Network is a self-organizing multi-hop wireless network where all hosts (often called nodes) participate in the routing and data forwarding process. The dependence on nodes to relay data packets for others makes mobile ad hoc networks extremely susceptible to various malicious and selfish behaviors. This point is largely overlooked during the early stage of MANET research. Many works simply assume nodes are inherently cooperative and benign. However, experiences from the wired world manifest that the reverse is usually true; and many works [3] [10] [9] [8] [12] [19] have pointed out that the impact of malicious and selfish users must be carefully investigated. The goal of this research is to address the cooperation problem and related security issues in wireless ad hoc networks. As a rule of thumb, it is more desirable to include security mechanisms in the design phase rather than continually patching the system for security breaches. As pointed out in [2] [1], there can be both selfish and malicious nodes in a mobile ad hoc network. Selfish nodes are most concerned about their energy consumption and intentionally drop packets to save power. The purpose of malicious nodes, on the other hand, is to attack the network using various intrusive techniques. In general, nodes in an ad hoc network can exhibit Byzantine behaviors.
Microarray technology and cancer gene profiling
Cancer is a heterogeneous disease in most respects, including its cellularity, different genetic alterations and diverse clinical behaviors. In the present book, written by leading experts in each field, the technical features characterizing this powerful laboratory tool are discussed, and the applications so far described in the field of oncology are reviewed.
Hybrid Systems : Computation and Control ; Vol.3927 ; 9th International Workshop, HSCC 2006, Santa Barbara, CA, USA, March 29-31, 2006, Proceedings
The focus is on modeling, analysis, and implementation of dynamic and reactive systems involving both discrete and continuous behaviors. Topics addressed include tools for analysis and verification, control and optimization, modeling, engineering applications, and new directions in language support and implementation.
Hybrid Systems : Computation and Control ; 11th International Workshop, HSCC 2008, St. Louis, MO, USA, April 22-24, 2008. Proceedings
Contains the proceedings ofthe 11th Workshop on Hybrid Systems: Computation and Control (HSCC 2008) held in St. Louis, Missouriduring April 22–24,2008.The annual workshop on hybrid systems focuses on research inbedded ,reactive systems in volving theinterplay between symbolic/switchingand continuous dynamical behaviors. HSCC attracts academic as well as industrial researchers to exchange information on the latest developments of applications and theoretical advancements in the design, analysis, control, optimization, and implementation of hybrid systems, with particular attention to embedded and networked control systems. We would like to thank the Program Committee members and the reviewers for an excellent job of evaluating the submissions and participating in the online Program Committee discussions.
Hormones and social behaviour
This book concentrates on two major topics: First, the molecular and neural biology of hormone actions relevant to normal social behaviors; and Second, the clinical treatment of human patients in whom these behaviors have gone wrong.
Handbook of multicultural perspectives on stress and coping
Has the developing world developed modern concepts of stress? Are coping methods the same around the globe? Such questions are not simple to answer, and until recently, few knew to ask them. In recent years, Western psychologists have recognized that their prevailing views of psychology do not always translate worldwide—and that no culture has a monopoly on either stress or coping. The Handbook of Multicultural Perspectives on Stress and Coping was created to address this realization. This unique volume moves beyond simple comparisons of behaviors in other countries by clarifying critical concepts in stress and coping, analyzing and synthesizing vast amounts of global data, and identifying constructs and methodologies necessary for meaningful cross-cultural research.
Green human resource management research : Issues, trends, and challenges
This book, engaging SDGs 4 and 8, among others, examines green HRM from a variety of perspectives. Divided into three sections, it explores the process of human resource acquisition, the connection between green HRM practice and employee behavior, and international perspectives of green HRM.
Foundation PHP for Dreamweaver 8
In this book, we look specifically at using Dreamweaver's built-in server behaviors to build dynamic web sites using PHP and MySQL, the world's most popular open source server-side language and database server combination, which are both reliable, powerful, and open source (and therefore free to use). This version of Dreamweaver includes more powerful support for PHP and MySQL than ever before, and we'll show you how to make this work for you. No previous experience of PHP or MySQL is necessary to use this book. Examples built throughout the book include a content management system, and an online image gallery. All examples are designed to meet modern usability requirements and be web standards-compliant.
Expressive Order : Confirming Sentiments in Social Actions
Expressive Order introduces affect control theory to lay readers of sociology, and additionally guides sociology specialists into the theory's deep structure. Briefly, affect control theory proposes that individuals shape their social interactions so that emerging impressions reinforce sentiments about salient identities, behaviors, and settings. Emotions signal how the process of confirming sentiments is going for each individual.
Exploring the Vertebrate Central Cholinergic Nervous System
The volume’s eleven chapters cover a wide variety of topics including the complexity of synthesis of acetylcholine, cholinesterases, cholinergic teratology, anticholinesterase agents, clinical use of cholinergic drugs, central cholinergic pathways and behaviors with cholinergic correlates. The figures and diagrams help illustrate various subjects and its photographs of "cholinergikes" of the past and present bring a personal note to the book. The book illustrates the peaks that have been reached in the course of the history of cholinergic research and challenges the perennial frontier of human science: the understanding of ourselves.
Establishing The Foundation Of Collaborative Networks ; IFIP TC 5 Working Group 5.5 Eighth IFIP Working Conference on Virtual Enterprises September 10-12, 2007, Guimarães, Portugal
While today production and service provision constitute the main areas of application for Collaborative Networks (CNs) worldwide, during the last decade the paradigm is extending to many new application areas. These developments emphasize the need for establishing a sounder foundation for collaborative networks, namely in terms of theoretical principles and formal models, capturing the concepts, entities, behaviors, and operations of the CNs, and developing technology-independent infrastructure architectures, tools and methodologies. This book includ represent a comprehensive overview of recent advances in various domains and lines of research and development on collaborative networks. There is a special emphasis on the CN topics related to trust aspects, performance and value systems, VO breeding environments, VO creation, e-contracting, collaborative architectures and frameworks, professional virtual communities, interoperability issues, business benefits, and case studies and applications in industry and services.
Essentials of consumer behavior
Essentials of consumer behavior offers an unique material on vulnerable consumers and ethics. Balancing a strong academic foundation with a practical approach, Stephens emphasizes that consumer behavior does not simply equate to buyer behavior. She examines the thoughts, feelings, and behaviors that shape consumers’ attitudes and motivations in relation to brands, products, and marketing messages. Providing a concise guide to the discipline, the author covers key themes such as vulnerable consumers, new technologies, and collaborative consumption.
Environments for Multi-Agent Systems ; 1st International Workshop, E4MAS, 2004, New York, NY, July 19, 2004, Revised Selected Papers
The modern ?eld of multiagent systems has developed from two main lines of earlier research. Its practitioners generally regard it as a form of arti?cial intelligence (AI). Some of its earliest work was reported in a series of workshops in the US dating from1980,revealinglyentitled,“DistributedArti?cialIntelligence,”andpioneers often quoted a statement attributed to Nils Nilsson that “all AI is distributed. ” The locus of classical AI was what happens in the head of a single agent, and much MAS research re?ects this heritage with its emphasis on detailed modeling of the mental state and processes of individual agents. From this perspective, intelligenceisultimatelythepurviewofasinglemind,thoughitcanbeampli?ed by appropriate interactions with other minds. These interactions are typically mediated by structured protocols of various sorts, modeled on human conver- tional behavior. But the modern ?eld of MAS was not born of a single parent. A few - searchershavepersistentlyadvocatedideasfromthe?eldofarti?ciallife(ALife). These scientists were impressed by the complex adaptive behaviors of commu- ties of animals (often extremely simple animals, such as insects or even micro- ganisms). The computational models on which they drew were often created by biologists who used them not to solve practical engineering problems but to test their hypotheses about the mechanisms used by natural systems. In the ar- ?cial life model, intelligence need not reside in a single agent, but emerges at the level of the community from the nonlinear interactions among agents. - cause the individual agents are often subcognitive, their interactions cannot be modeled by protocols that presume linguistic competence.
