الصفحة 1
الصفحة 1
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Open and Toroidal Electrophoresis : Ultra-High Separation Efficiencies in Capillaries, Microchips and Slabs

Written by one of the developers of Toroidal Capillary Electrophoresis (TCE), this book is the first to present this novel analytical technique, in detail, to the field of analytical chemistry. The exact expressions of separation efficiency, resolution, peak capacity, and many other performance indicators of the open and toroidal layouts are presented and compared.

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One hundred years of social protection : The changing social question in Brazil, India, China, and South Africa

As the first in-depth study of the ideational foundations of social protection policies and programmes in these four countries, the contributions demonstrate that the social question was articulated in an increasingly inclusive way.

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Oncogenes Meet Metabolism : From Deregulated Genes to a Broader Understanding of Tumour Physiology

In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).

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Office Andrology

The investigation and management of male infertility can be a formidable diagnostic challenge to family physicians, urologists, and reproductive specialists alike. In Office Andrology, noted clinical physicians and scientists have joined forces to create a comprehensive resource guide to current diagnostic and treatment options for a broad spectrum of clinical issues relevant to male infertility disorders. Topics covered range from basic sperm biology and male reproductive endocrinology, to immunology, specialized sperm testing, and the genetic background to male infertility. Although emphasis is on the investigation, diagnostic testing, and management of the infertile male, controversial medical and surgical treatment options are also fully discussed. For the reproductive specialist, the text thoughtfully reviews such timely issues as gender selection, human immunodeficiency virus-discordance couples, and posthumous reproduction. Other topics of interest include laboratory accreditation, vasectomy reversal, ethical and legal considerations of donor insemination, optimizing success in a donor insemination program, and strategic therapies for ejaculatory disorders and erectile dysfunction in infertile men.

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Obstetric Anesthesia Handbook

As the field of obstetric anesthesia continues to change rapidly, both in technique and in specific pharmaceutical agents used, it is essential for all practitioners caring for the pregnant patient to be familiar with current anesthetic protocols and general concepts in obstetric anesthesia. The Handbook appeals to a wide audience, as it was written with the practicing anesthesiologists in mind, as well as nurse anesthetists, obstetricians, housestaff, and residents. The Obstetric Anesthesia Handbook supplies expert advice on every facet of anesthesia for childbirth and related obstetric procedures. The text is authoritative, succinct, and highly practical. It is accompanied by over 100 illustrations and tables making the text a convenient reference to the busy practitioner.

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Nutritional psychiatry : A primer for clinicians

There is increasing evidence that mental health problems such as schizophrenia, depression and anxiety are linked with poor nutrition. At present, very few psychiatrists provide nutritional advice for their patients, despite such advice complimenting drug and psychological therapies. This edited volume is the first book to provide a comprehensive overview of the relationship between nutrition and mental health, for mental health professionals. Featuring contributions from leading authorities in the field, the book examines the link between diet and the microbiome-gut brain axis and how this correlates with a variety of psychiatric disorders. The book explores how enhancing the beneficial bacteria in the gut, through the use of psychobiotics, prebiotics or dietary change can improve mood and reduce anxiety.

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Nutritional Management of the Surgical Patient

Provides the first comprehensive evidence-based overview of the nutritional and dietary therapies for surgical patients. It takes clinicians through every stage of surgery, from pre-operative and immediate post-operative care, through to long term recovery and survivorship. This book describes the impact of surgical procedures and their complications and the effect these have on nutritional status as well as the nutritional strategies utilised to manage patients in these settings.

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Nutrition and Rheumatic Disease

It is difficult, if not impossible, for health care providers to remain at the forefront of knowledge for all aspects of nutrition and rheumatic diseases. In Nutrition and Rheumatic Disease, experts provide a comprehensive review of current knowledge regarding nutrition and dietary management for the complex set of rheumatic conditions. Within the disease-specific chapters, the authors present a historical perspective, a discussion of the major clinical features, current management and treatment, a review of the literature related to nutritional status and diet, and dietary recommendations, based on current scientific evidence. The field of rheumatic diseases includes a wide variety of pathologic processes. Adequate reviews of the scientific literature on each of the rheumatic diseases in Nutrition and Rheumatic Disease alleviate the inherent confusion surrounding the risks and benefits of various dietary therapies.

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Nutrigenomics and nutraceuticals

Provides an authoritative and comprehensive overview of the field of nutraceuticals and genomics—also called nutrigenomics, a rapidly growing field. It discusses both nutrigenomic and nutrigenetic techniques to investigate the nutritional basis of several health disorders because scientists have found that diet can affect gene expression. The book covers the nutrigenomic tools for the prevention of disease conditions such as cancer, viral infection, microbial infection, COVID-19, HIV/AIDS, tuberculosis, hypertension, neurodegenerative disease, obesity, baldness, and anemia. Some nutrigenomic tools that can also be used for brain health, weight loss, human nutrition, skin care, and maintaining health during pregnancy are also explored.

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Nutraceuticals in insomnia and sleep problems

Sleep is one of the most important and crucial physiological needs for maintaining a healthy life. However, in today’s day and age, insomnia and other sleep disorders, such as sleep apnea, are increasing rapidly. This new book details the nutraceuticals from foods that help to promote good health and optimum sleep. The authors discuss the importance of sleep, the role of diet in sleep, the role of specific vitamins and minerals, amino acids and opioids as nutraceuticals for sleep, newer technologies for use and delivery of nutraceuticals for treating insomnia, and more. The book not only explores nutraceuticals that promote optimum sleep but also details foods that cause insomnia, such as processed, chemical-rich, and refined foods. Chapters also cover commensal and symbiotic microbes, microbial metabolites, and bacteriocins and their impact on sleep. A chapter on the ethical issues related to addiction to nutraceuticals for sleep induction is also included.

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Nutraceuticals in arthritis and psoriasis : Management and prevention of diseases

Explores plant-derived nutraceuticals that can be used as crucial therapeutic tools in the prevention and treatment of arthritis and psoriasis, providing detailed information on the use of plant-derived nutraceuticals, such as microalgae and other marine botanicals, omega polyunsaturated fatty acids, glucosamine and chondroitin sulphate, plant-based gum, vitamins and oils, probiotic supplements, and others in the treatment and management of arthritis and psoriasis. The book relates the recent scientific evidence on the effectiveness of each of these nutraceutical treatments, offering case studies, results of clinical studies, and more.

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Notions of Convexity

The first two chapters of this book are devoted to convexity in the classical sense, for functions of one and several real variables respectively. This gives a background for the study in the following chapters of related notions which occur in the theory of linear partial differential equations and complex analysis such as (pluri-)subharmonic functions, pseudoconvex sets, and sets which are convex for supports or singular supports with respect to a differential operator. In addition, the convexity conditions which are relevant for local or global existence of holomorphic differential equations are discussed, leading up to Trépreau’s theorem on sufficiency of condition (capital Greek letter Psi) for microlocal solvability in the analytic category.

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Notch Signaling in Embryology and Cancer : Notch Signaling in Cancer

This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more.

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Norwegian Shipping in the 20th Century : Norway's Successful Navigation of the World's Most Global Industry

This open access book discusses how Norwegian shipping companies played a crucial role in global shipping markets in the 20th century, at times transporting more than ten per cent of world seaborne trade. Chapters explore how Norway managed to remain competitive, despite being a high labour-cost country in an industry with global competition. Among the features that are emphasised are market developments, business strategies and political decisions The Norwegian experience was shaped by the main breaking points in 20th century world history, such as the two world wars, and by long-term trends, such as globalization and liberalization. The shipping companies introduced technological and organizational innovations to build or maintain a competitive advantage in a rapidly changing world. The growing importance of offshore petroleum exploration in the North Sea from the 1970s was both a threat and an opportunity to the shipping companies. By adapting both business strategies and the political regime to the new circumstances, the Norwegian shipping sector managed to maintain a leading position internationally.

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Non-University Higher Education in Europe

This book represents the first-of-its-kind comprehensive discussion of the non-university higher education sector in Europe. Higher education throughout the world is facing rapid change. Despite the enormous attention devoted to that reality, this volume fills an important void. It describes and offers critical comparisons between the systems in 10 European countries. The book brings together the thinking of leading scholars on the non-university sectors in Austria, Belgium, Finland, Germany, Ireland, the Netherlands, Norway, Portugal, Spain, and the United Kingdom, with a chapter devoted to each country. National case studies are presented for the non-university sector in these countries that address issues such as historical developments, policy changes, governance structures, levels of institutional autonomy and future trends.

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Nonlinear Elliptic and Parabolic Problems : A Special Tribute to the Work of Herbert Amann

The present volume is dedicated to celebrate the work of the renowned mathematician Herbert Amann, who had a significant and decisive influence in shaping Nonlinear Analysis. Most articles published in this book, which consists of 32 articles in total, written by highly distinguished researchers, are in one way or another related to the scientific works of Herbert Amann. The contributions cover a wide range of nonlinear elliptic and parabolic equations with applications to natural sciences and engineering. Special topics are fluid dynamics, reaction-diffusion systems, bifurcation theory, maximal regularity, evolution equations, and the theory of function spaces.

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Nonequilibrium Carrier Dynamics in Semiconductors ; Proceedings of the 14th International Conference, July 25-29, 2005, Chicago, USA

International experts gather every two years at this established conference to discuss recent developments in theory and experiment in non-equilibrium transport phenomena. These developments have been the driving force behind the spectacular advances in semiconductor physics and devices over the last few decades. Originally known as "Hot Carriers in Semiconductors," the 14th conference in the series covered a wide spectrum of traditional topics dealing with non-equilibrium phenomena, ranging from quantum transport to optical phenomena in mesoscopic and nano-scale structures. Particular attention was given this time to emerging areas of this rapidly evolving field, with many sessions covering terahertz devices, high field transport in nitride semiconductors, spintronics, molecular electronics, and bioelectronics applications.

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Noise-Induced Transitions : Theory and Applications in Physics, Chemistry, and Biology

This classic text, an often-requested reprint, develops and explains the foundations of noise-induced processes. At its core is a self-contained, textbook-style presentation of the elements of probability theory, of the theory of Markovian diffusion processes and of the theory of stochastic differential equations, on which the modeling of fluctuating natural and artificial environments is based. Following an introduction to the mathematical tools, the occurrence and the properties of noise-induced transitions are then analyzed for rapidly fluctuating environments describable by the white-noise idealization. Subsequently, more realistic and general types of colored noises are considered. Appropriate practical methods for dealing with these situations are developed. The latter part of the book contains applications and experimental studies illustrating the many facets of noise-induced transitions. The following applications are considered in Noise-Induced Transitions: population dynamics, electrical circuits, chemical and photochemical reactions, non-linear optics, and hydrodynamical systems.

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Nitrogen therapy

Cryotherapy: is a surgical method using the application of low temperatures to living tissue, resulting in tissue destruction. It is an extremely valuable alternative to more invasive surgical option because of its cost effectiveness, excellent aesthetic results, and rapid delivery. With proper training, common skin diseases can be treated in a variety of settings, such as ambulatory surgical areas, doctors' offices, and nursing homes.

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Nicotinic Acetylcholine Receptor Signaling in Neuroprotection

Presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical and laboratory neuropharmacology and neurochemistry, this volume provides in-depth coverage of neuroprotection in basic research and future developments in the clinical application of effective neuroprotective strategies in neurodegenerative diseases. This work appeals to both basic and clinical researchers in several fields, such as neuroscience, neurology, and pharmacology.

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