الصفحة 1
الصفحة 1
Oil-in-Water Nanosized Emulsions for Drug Delivery and Targeting
ompiles the step-by-step investigations made concerning the potential of nanosized emulsions on both drug delivery and drug targeting areas by different group of scientists in various laboratories across the world Inverts the common nano-emulsions coverage trend of focusing on focused on the particulate system itself, instead exploring the way to turn nanosized emulsions as biomedical tool, as well as, treating the in vitro and in vivo aspects after administration Provides an overview of the current state-of-the art regarding the development of tocol emulsions, emulsion adjuvants in immunization research, oxygen-carrying emulsions (called as fluorocarbon emulsion) and emulsions for delivering drugs to nasal and topical (ocular and transdermal) routes
Ocular Transporters in Ophthalmic Diseases and Drug Delivery
This exceptionally important new work represents recent discoveries and advancements in the study of ocular transporters and their roles in ocular physiology, pathology, and drug delivery. Transporters are found on the membranes of cells and play a key role in transmitting signals between cells. In Ocular Transporters in Ophthalmic Diseases and Drug Delivery, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium, and the transport of nutrients across the retinal pigment epithelium. It also provides an in-depth look at how mutations or dysfunction of specific transporters can contribute to various disorders in the eye, including blindness, and provides readers with potential targets and strategies to allow safe passage of therapeutic drugs into the eye.
Nutrition, chemistry, and health effects of sugar, salt, and milkfat
Covers sugar, salt and milk fat from a chemical perspective, and presents an overview of the role of these ingredients in our food, focusing on their flavors, satiety-inducing properties, nutritional impact, and health effects. The book begins with a chapter devoted to the chemical composition of these taste enhancers and satiety-inducing components, followed by a chapter that sheds light on the persuasive tactics employed by the food industry and their impact on consumer behavior, ultimately discussing the complex relationship between marketing strategies and public health. In Chapter 3, the author presents case studies and explores the nutritional requirements of these ingredients, while considering their physiological effects ad potential implications for human health. In Chapter 4, the author evaluates current consumption patterns and their implications, analyzing trends, policies, and opportunities to shape healthier dietary choices.
Numerical Optimization
Numerical Optimization presents a comprehensive and up-to-date description of the most effective methods in continuous optimization. It responds to the growing interest in optimization in engineering, science, and business by focusing on the methods that are best suited to practical problems.The book has been thoroughly updated throughout. There are new chapters on nonlinear interior methods and derivative-free methods for optimization, both of which are used widely in practice and the focus of much current research. Because of the emphasis on practical methods, as well as the extensive illustrations and exercises.
Nuclear Condensed Matter Physics with Synchrotron : Basic Principles, Methodology and Applications
This book provides a comprehensive introduction to the growing field of nuclear condensed matter physics with synchrotron radiation, a technique which finds numerous applications in fields such as magnetism, physics of surfaces and interfaces, lattice dynamics and more. Due to the enormous brilliance of modern synchrotron radiation sources, the method is particularly suited for the investigation of low-dimensional structures such as thin films and nanoparticles. The use of isotopic probe layers, for example, allows one to determine magnetic and vibrational properties with very high spatial resolution; focusing techniques and x-ray interference effects lead to a very high sensitivity for smallest amounts of material. The book is written on an introductory level with many examples employed to illustrate the special experimental possibilities.
Nonsmooth Vector Functions and Continuous Optimization
A recent significant innovation in mathematical sciences has been the progressive use of nonsmooth calculus, an extension of the differential calculus, as a key tool of modern analysis in many areas of mathematics, operations research, and engineering. Focusing on the study of nonsmooth vector functions, this book presents a comprehensive account of the calculus of generalized Jacobian matrices and their applications to continuous nonsmooth optimization problems and variational inequalities in finite dimensions.
New Tools of Economic Dynamics
New Tools of Economic Dynamics gives an introduction and overview of recently developed methods and tools, most of them developed outside economics, to deal with the qualitative analysis of economic dynamics. It reports the results of a three-year research project by a European and Latin American network on the intersection of economics with mathematical, statistical, and computational methods and techniques. Focusing upon the evolution and manifold structure of complex dynamic phenomena, the book reviews and shows applications of a variety of tools, such as symbolic and coded dynamics, interacting agents models, microsimulation in econometrics, large-scale system analysis, and dynamical systems theory. It shows the potential of a comprehensive analysis of growth, fluctuations, and structural change along the lines indicated by pioneers like Harrod, Haavelmo, Hicks, Goodwin, Morishima, and it highlights the explanatory power of the qualitative approach they initiated.
New Horizons for Asian Museums and Museology
This book presents up-to-date information about museums and museology in present-day Asia, focusing on Japan, Mongolia, Myanmar, and Thailand. Asian countries today have developed or are developing their own museology and museums, which are not simple copies of European or North American models. This book provides readers with carefully chosen examples of museum activities—for example, exhibition and sharing information, database construction, access to and conservation of museum collections, relationships between museums and local communities, and international cooperation in the field of cultural heritage.
New Drug Development for Known and Emerging Viruses
This book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic.
Natural occurrence and biological activities of quinoline derivatives
Provides a comprehensive overview of quinoline derivatives, focusing on their chemical structure, biological activities, and therapeutic benefits. It delves into the natural sources of these derivatives, covering their isolation, characterization, and potential therapeutic applications, particularly in areas such as anti-cancer, anti-inflammatory, antimicrobial, and antimalarial activity. With its emphasis on providing valuable reference material, this book is an indispensable resource for researchers, educators, and professionals in the fields of chemistry, biology, pharmacology, and drug discovery.
NATO and terrorism catastrophic terrorism and first responders : Threats and mitigation
In this important new book a group of experts represents the current knowledge on the various terrorism threats to first responders resulting from the novel use of conventional weapons, as well radiological, nuclear, biological and chemical weapons. Also, the current situation in selected countries of different sizes and practical experience with terrorism countermeasures (Austria, Israel, Slovenia, Russia, U.S.) is reviewed, focusing on the national operational logistics and the individual needs for improving the present situation. Finally, this book offers innovative solutions to strengthen the level of protection of the first responders, culminating in fifty-one practically applicable recommendations
NanoBiotechnology : BioInspired Devices and Materials of the Future
NanoBioTechnology: BioInspired Devices and Materials of the Future is a groundbreaking text that will assist scientists and students in learning the fundamentals and cutting-edge nature of this new and emerging science. Focusing on materials and building blocks for nanotechnology, leading scientists from around the world share their knowledge and expertise in this authoritative volume. The volume is broken into five sections. The first section presents an overview of nanotechnology and describes the many aspects of the field. Section 2 details biological materials serving as nanotemplates for bottom-up fabrication. Section 3 covers the use of biological macromolecules for electron transfer and computation. Section 4 presents a brief overview of the extensive and rapidly growing field of nanomedicine. Finally, Section 5 details de-novo designed structures and the various approaches different scientific groups take with molecular level training and language
Museum Digitisations and Emerging Curatorial Agencies Online : Vikings in the Digital Age
This book explores the multiple forms of curatorial agencies that develop when museum collection digitisations, narratives and new research findings circulate online. Focusing on Viking Age objects, it tracks the effects of antagonistic debates on discussion forums and the consequences of search engines, personalisation, and machine learning on American-based online platforms. Furthermore, it considers eco-systemic processes comprising computation, rare-earth minerals, electrical currents and data centres and cables as novel forms of curatorial actions.
Multimedia Semantics : The Role of Metadata
This book gives an overview on fundamental issues within the field of multimedia metadata focusing on contextualized, ubiquitous, accessible and interoperable services on a higher semantic level. The book in hand provides a selection of basic articles being a base for multimedia metadata research. Furthermore it presents a view on the current state of the art in multimedia metadata research.
Modern cryptography ; Vol.1 : A classical introduction to informational and mathematical principle
This book systematically explores the statistical characteristics of cryptographic systems, the computational complexity theory of cryptographic algorithms and the mathematical principles behind various encryption and decryption algorithms. The theory stems from technology. Based on Shannon's information theory, this book systematically introduces the information theory, statistical characteristics and computational complexity theory of public key cryptography, focusing on the three main algorithms of public key cryptography, RSA, discrete logarithm and elliptic curve cryptosystem.
Modern Construction Handbook
Tried and tested component details, examples focusing on sustainability and energy consumption, and an update on finite element analysis (FEA) and computational fluid dynamics (CFD) introduced in the last edition set new standards for this handbook which serves as a foundational textbook in many architecture courses
Modern architecture and climate design before air conditioning
explores how leading architects of the twentieth century incorporated climate-mediating strategies into their designs, and shows how regional approaches to climate adaptability were essential to the development of modern architecture. Focusing on the period surrounding World War II'before fossil-fuel powered air-conditioning became widely available'Daniel Barber brings to light a vibrant and dynamic architectural discussion involving design, materials, and shading systems as means of interior climate control. He looks at projects by well-known architects such as Richard Neutra, Le Corbusier, Lúcio Costa, Mies van der Rohe, and Skidmore, Owings, and Merrill, and the work of climate-focused architects such as MMM Roberto, Olgyay and Olgyay, and Cliff May. Drawing on the editorial projects of James Marston Fitch, Elizabeth Gordon, and others, he demonstrates how images and diagrams produced by architects helped conceptualize climate knowledge, alongside the work of meteorologists, physicists, engineers, and social scientists. Barber describes how this novel type of environmental media catalyzed new ways of thinking about climate and architectural design.
Modelling in Mechanical Engineering and Mechatronics : Towards Autonomous Intelligent Software Models
Modelling in Mechanical Engineering and Mechatronics presents a model-centred approach focusing on distributed development and use of autonomous intelligent software models, particularly the efficiency of the models, and their interaction and integration into distributed autonomous intelligent systems. In order to systematise the available knowledge, a domain ontology is presented; a subset of which is used to create a modelling theory based on knowledge and experience in the areas of software engineering, mechanical engineering and mechatronics. This holistic view of modelling explains the purpose and the essence of modelling, as well as the benefits that are to be expected. It discusses the relations to other branches of engineering and science and as a result, it demonstrates strategies, methods and tools for unleashing the full power of modelling.
Modeling decisions : Information fusion and aggregation operators
This book covers the underlying science and application issues related to aggregation operators, focusing on tools used in practical applications that involve numerical information. Starting with detailed introductions to information fusion and integration, measurement and probability theory, fuzzy sets, and functional equations.
Modeling and Using Context ; 5th International and Interdisciplinary Conference, CONTEXT 2005, Paris, France, July 5-8, 2005, Proceedings
Context is of crucial importance for research and applications in many disciplines, as evidenced by many workshops, symposia, seminars, and conferences on specific aspects of context. The International and Interdisciplinary Conference on Modeling and Using Context (CONTEXT), the oldest conference series focusing on context, provides a unique interdisciplinary emphasis, bringing together participants from a wide range of disciplines, including artificial intelligence, cognitive science, computer science, linguistics, organizational science, philosophy, psychology, ubiquitous computing, and application areas such as medicine and law, to discuss and report on context-related research and projects. Previous CONTEXT conferences were held in Rio de Janeiro, Brazil (1997), Trento, Italy (1999, LNCS 1688), Dundee, UK (2001, LNCS 2116), and Palo Alto, USA (2003, LNCS 2680). CONTEXT 2005 was held in Paris, France during July 5–8, 2005. There was a strong response to the CONTEXT 2005 Call for Papers, with 120 submissions received. A careful review process assessed all submissions, with each paper first reviewed by the international Program Committee, and then reviewer discussions were initiated as needed to assure that the final decisions carefully considered all aspects of each paper. Reviews of submissions by the Program Chairs were supervised independently and anonymously, to assure fair consideration of all work. Out of the 120 submissions, 23 were selected as full papers for oral presentation, and 20 were selected as full papers for poster presentation. These outstanding papers are presented in this proceedings.
