25 Years of P53 Research
Communication, awareness and access to information: Given the complexity of the field and the fact that data pertaining to each particular aspects of p53 biology or deregulation are scattered in many different publications, it is extremely difficult to access the full scale of relevant information of any specific p53-related topic. This book may help in this task by putting into perspective both general considerations on the p53 pathway and more specific information on various aspects of p53. In the longer term, however, open access to p53 complexity will require the development of knowledge bases accessible through the web and using simple navigation tools to guide users towards the specific information they need. Several efforts are currently being developed in that direction. They need to be strenghtened and better integrated within the rapidly growing galaxy of web-based information sources on molecular and individual variations in cancer. 2. Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard, universally accepted assays to measure critical p53 protein functions.
150 Best New Bathroom Ideas
Showcasing an extensive collection of designs and style, captured in stunning full-color photos, 150 Best New Bathroom Ideas provides an in-depth review of outstanding bathroom designs from internationally renowned architects and designers. Here are the most attractive, functional, and cost-effective bathroom concepts from around the world. Practical yet beautiful and stylish, 150 Best New Bathroom Ideas includes innovative ideas for lighting, floor, wall, and window treatments, and for showers, toilets, sinks, and bathtubs. An essential design and decorating reference, 150 Best New Bathroom Ideas covers the diversity of current trends and is an inspirational source for homeowners, designers, interior decorators, and architects.

