الصفحة 95
الصفحة 95
Cellular Automaton Modeling of Biological Pattern Formation: Characterization, Applications, and Analysis
This book focuses on a challenging application field of cellular automata: pattern formation in biological systems, such as the growth of microorganisms, dynamics of cellular tissue and tumors, and formation of pigment cell patterns. These phenomena, resulting from complex cellular interactions, cannot be deduced solely from experimental analysis, but can be more easily examined using mathematical models, in particular, cellular automaton models.
Cellular Automata and Discrete Complex Systems ; 26th IFIP WG 1.5 International Workshop, AUTOMATA 2020, Stockholm, Sweden, August 10–12, 2020, Proceedings
This volume constitutes the refereed post-conference proceedings of the 26th IFIP WG 1.5 International Workshop on Cellular Automata and Discrete Complex Systems, AUTOMATA 2020, held in Stockholm, Sweden, in August 2020. The workshop was held virtually. The 11 full papers presented in this book were carefully reviewed and selected from a total of 21 submissions. The topics of the conference include dynamical, topological, ergodic and algebraic aspects of CA and DCS, algorithmic and complexity issues, emergent properties, formal languages, symbolic dynamics, tilings, models of parallelism and distributed systems, timing schemes, synchronous versus asynchronous models, phenomenological descriptions, scientific modeling, and practical applications.
Cell-secreted vesicles : Methods and protocols
Pesents hands-on technological protocols used to target an array of cell-secreted extracellular vesicles (EVs) in a variety of biological systems. Beginning with methods for EV purification and analysis, the book continues with sections on the study of EV functions as well as specific systems and models allowing for the study of EVs of different origin. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cell-Cell Channels
The biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. This concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration—as a Cell Body—these two items comprise the fundamental functional and struc tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.
Cell Therapy, Stem Cells and Brain Repair
As our world continues to evolve, the field of regenerative medicine f- lows suit. Although many modern day therapies focus on synthetic and na- ral medicinal treatments for brain repair, many of these treatments and prescriptions lack adequate results or only have the ability to slow the p- gression of neurological disease or injury. Cell therapy, however, remains the most compelling treatment for neurodegenerative diseases, disorders, and injuries, including Parkinson’s disease, Huntington’s disease, traumatic brain injury, and stroke, which is expanded upon in more detail in Chapter 1 by Snyder and colleagues. Cell therapy is also unique in that it is the only therapeutic strategy that strives to replace lost, damaged, or dysfunctional cells with healthy ones.
Cell therapy stem cells and regenerative medicine
Provides an overview of cell-based therapy for human diseases including the definition, history, and clinical applications of human stem cells and their use in regenerative medicine. It covers human pluripotent stem cells (human embryonic stem cells and human induced pluripotent stem cells), mesenchymal stem/stromal cells, and hematopoietic stem cells, bone marrow mononuclear cells. In terms of clinical applications, this book also provides an update on recent human trials using these cells to treat various diseases, including neurological disorders, pulmonary dysfunctions, metabolic/endocrine-related diseases, frailty, and cancer treatment. In addition, it discusses the authors’ clinical trial experiences related to these conditions in a clinical setting to provide additional insight into regenerative medicine, especially cell-based therapy.
Cell Surface Receptors : A Short Course on Theory and Methods
Cell Surface Receptors: A Short Course on Theory and Methods, 3rd Edition, links theoretical insights into drug-receptor interactions described in mathematical models with the experimental strategies to characterize the biological receptor of interest.
Cell Motility
Cell motility is a fascinating example of cell behavior which is fundamentally important to a number of biological and pathological processes. It is based on a complex self-organized mechano-chemical machine consisting of cytoskeletal filaments and molecular motors. In general, the cytoskeleton is responsible for the movement of the entire cell and for movements within the cell. The main challenge in the field of cell motility is to develop a complete physical description on how and why cells move. For this purpose new ways of modeling the properties of biological cells have to be found. This long term goal can only be achieved if new experimental techniques are developed to extract physical information from these living systems and if theoretical models are found which bridge the gap between molecular and mesoscopic length scales. Cell Motility gives an authoritative overview of the fundamental biological facts, theoretical models, and current experimental developments in this fascinating area.
Cell Division Control in Plants
The molecular mechanisms controlling cell cycle progression are highly conserved in eukaryotes. In addition to the basic protein machinery involved in cell cycle regulation, higher plants have also evolved unique molecular mechanisms that allow integration of environmental, physiological, and developmental signals into networks to control proper cell division and expansion. Rapid and exciting research progress in these fields has been achieved from experimental observations on plants over the past decade. The scope of this volume is focused on the molecular basis of all aspects of cell division and cytokinesis in plants. It is an essential reference book for instructors and scientists working in the areas of molecular, cell, and developmental biology of plants. The editors of this book are veterans in the field of plant molecular biology and highly respected worldwide.
Causality of Psychological Injury : Presenting Evidence in Court
This sequel to the authors’ Psychological Knowledge in Court offers a welcome expansion on key concepts, terms, and issues in causality, bringing much needed clarity to psychological injury assessments and the legal contexts that employ them. Focusing on PTSD, traumatic brain injury, and chronic pain (and grounding readers in salient U.S. and Canadian case law), Causality sets out a multifactorial causality framework to facilitate admissibility of psychological evidence in court. Issues concerning malingering are examined in depth, as are clinical gray areas that can jeopardize validity. At the same time, the book clearly explains what lawyers and clinicians need to understand about each other’s work—of crucial importance since the two sides often seem to speak at cross-purposes.
Categories for software engineering
This book provides a gentle, software engineering oriented introduction to category theory. Assuming only a minimum of mathematical preparation, this book explores the use of categorical constructions from the point of view of the methods and techniques that have been proposed for the engineering of complex software systems: object-oriented development, software architectures, logical and algebraic specification techniques, models of concurrency, inter alia. After two parts in which basic and more advanced categorical concepts and techniques are introduced, the book illustrates their application to the semantics of CommUnity – a language for the architectural design of interactive systems. "For computer scientists, this unique book presents Category Theory in a manner tailored to their interests and with examples to which they can relate." Ira Forman, IBM "This book applies little-known yet quite powerful formal tools from category theory to software structures: designs, architectures, patterns, and styles. Rather than focus on issues at the level of computational models and semantics, it instead applies these tools to some of the problems facing the sophisticated software architect.
Categories and Sheaves
This book covers categories, homological algebra and sheaves in a systematic and exhaustive manner starting from scratch, and continues with full proofs to an exposition of the most recent results in the literature, and sometimes beyond.The authors present the general theory of categories and functors, emphasising inductive and projective limits, tensor categories, representable functors, ind-objects and localization. Then they study homological algebra including additive, abelian, triangulated categories and also unbounded derived categories using transfinite induction and accessible objects. Finally, sheaf theory as well as twisted sheaves and stacks appear in the framework of Grothendieck topologies.
Case Studies in Environmental Archaeology
Environmental archaeology encompasses the application of biological and geological techniques to the study of human/environmental interactions. Each chapter is an original or revised work by internationally-recognized geoarchaeologists, human biologists, paleoethnobotanists, and zooarchaeologists. Each study demonstrates how and why the information obtained using environmental techniques is important to anthropologists instead of describing, critiquing, or advocating a method. These ethnographic, geological, and biological case studies successfully demonstrate the application of environmental science toward the resolution of questions related to human behavior in the past.
Case studies in biocultural diversity from Southeast Asia : Traditional ecological calendars, Folk medicine and Folk names
This book demonstrates the linkages between local languages, traditional knowledge, and biodiversity at the landscape level in Asia, providing a fresh approach to discussions on Asia’s biocultural diversity. The book carries forward earlier analyses but importantly focuses on ‘traditional ecological calendars,’ ‘folk medicine,’ and ‘folk names’ in the context of the vital importance of maintaining biological, cultural, and linguistic diversity. It does this by addressing a range of cases and issues in relation to Southeast Asia: Brunei Darussalam, Indonesia, Malaysia, the Philippines, and North-East India. The several chapters demonstrate the ways in which the various forms of knowledge of the environment and its categorizations are important in areas such as landscape and resource management and conservation. They also demonstrate that environmental knowledge and the practical skills which accompany it are not necessarily widely shared. This book sends important messages to those who care about the sustainability of our environment, the maintenance of its biocultural diversity, or at least the maintenance of what remains of it because much has changed.
Carotenoids ; Vol.4 : Natural Functions
The Carotenoids book series provides detailed accounts of the fundamental chemistry of carotenoids and the basic methods used in carotenoid research, and critical discussions of the biochemistry, functions and applications of these important compounds. Volume 4 and its companion, Volume 5, deal with the functions of carotenoids in all kinds of living organisms and the actions of carotenoids in human nutrition and health. The material presented in the earlier Volumes is all relevant to studies of biological functions and actions. In particular, biological studies must be supported by a rigorous analytical base. The various analytical procedures described in Volumes 1A and 1B, supplemented by the data for individual compounds given in the Carotenoids Handbook, must be understood and applied correctly, whether they are being used for quantitative analysis, identification or in complex studies of carotenoids in situ.
Career development in bioengineering and biotechnology : Roads well laid and paths less traveled
Career Development in Bioengineering and Biotechnology is an indispensable guide to some of the most exciting career and professional growth opportunities in science, engineering, and beyond, and a "must read" for anyone interested in a career related to this burgeoning field.
Care in Healthcare : Reflections on Theory and Practice
This book examines the concept of care and care practices in healthcare from the interdisciplinary perspectives of continental philosophy, care ethics, the social sciences, and anthropology. Areas addressed include dementia care, midwifery, diabetes care, psychiatry, and reproductive medicine. Special attention is paid to ambivalences and tensions within both the concept of care and care practices. Contributions in the first section of the book explore phenomenological and hermeneutic approaches to care and reveal historical precursors to care ethics. Empirical case studies and reflections on care in institutionalised and standardised settings form the second section of the book.
Cardiovascular English
The multiplicity of cardiological tests and therapeutical procedures demands a sound knowledge of cardiological English and can be extremely demanding for non-native English speaking cardiologists, cardiology residents, nurses, and medical students.
Cardiac reconstructions with allograft tissues
Cryopreserved allograft tissues are now standard materials for the reconstructive cardiac surgeon. Since publication of the first edition ("Cardiac Reconstructions with Allograft Valves") in 1989, the field has progressed dramatically with increased clinical use of cardiovascular allograft tissues, with the development of new surgical techniques, and with advances in the understanding of the fundamentals of valve transplantation biology and cryopreservation. As a result, over two-thirds of the present volume represents new material. Fifty-six authors bring their expertise to thirteen comprehensive, lavishly illustrated sections which discuss the principles of the use of homograft valves, major clinical series of homograft valves for both left and right ventricular outflow tracts, cryopreserved allograft tissue for cardiac reconstruction, cell biology of heart valve leaflets, cryobiology of heart valve preservation, morphological, biochemical, and explant pathology studies of allograft heart valves, allograft valve banking, as well as detailed explanation of surgical techniques for valve and root methods for left and right ventricular outflow tract reconstructions, the Ross operation and variants, and complex reconstructions. A final section presents potential future directions for the field. Over 400 illustrations, created expressly for this book, depict the surgical techniques from the perspective of the surgeon standing at the operating table.
Carcinoma della cervice uterina : Eziopatogenesi e profilassi = Carcinoma of the uterine cervix : Aetiopathogenesis and prophylaxis
The volume offers a synthetic and updated picture of a complex topic that includes the multifactorial etiopathogenesis of cervical cancer, the characteristics of the virus, the dynamics of HPV infections, the histological lesions of the cervix leading to cervical cancer. and the characteristics of the various surgical treatments, the current strategies for early diagnosis through the use of molecular assays currently on the market, up to the trials of the two vaccines recently registered also in Italy.
