الصفحة 94
الصفحة 94
Cannabinoids and the brain
Cannabinoids and the Brain gives a comprehensive overview of all the essential literature concerning the endocannabinoid and related systems in the nervous tissue. It is a rapidly expanding research field and the widespread presence of cannabinoids in most physiopathological mechanisms appear to hinder the effort to fully cover the subject. By the end of the book, the reader will have a solid knowledge of the genetics, molecular biology, anatomy, pharmacology, and physiology of the endocannabinoid system and its involvement in neurological and psychiatric disorders, and will eventually discover a natural relationship among marijuana, aspirin, and chili pepper.
Cancer Stem Cells : Novel Concepts and Prospects for Tumor Therapy
This book describes the recent developments in the emerging field of cancer stem cells. Their possible impact for the identification of novel treatment paradigms for cancer are discussed. The book will mainly be of interest to scientists and clinicians involved in cancer research, or to students wishing to enter into this area.
Cancer Prevention
This volume contains the main proceedings of the fourth international conference on "Cancer Prevention 2006," which was held during February 16–18, 2006, in St. Gallen, Switzerland. Written by international experts in the field, the book comprises a comprehensive update on the most recent developments in the upsurging fields of molecular biology and cancer genetics and their interactions with clinical epidemiology and cancer prevention at various levels: genetic/biologic predisposition and definition of high-risk groups; preclinical models and tumor prevention; prospects of surrogate endpoints and biomarkers; progress in imaging and detection of neoplastic precursor lesions.
Cancer du testicule = Testicular cancer
Testicular cancer has benefited from important therapeutic advances radically transforming its prognosis. Recent protocols have led to the development of treatments that maintain therapeutic efficacy while favoring quality of life and minimizing the sequelae (such as fertility disorders) in these often young men. This book discusses the various technical advances both in the field of diagnosis - with the contribution of modern imaging and anatomopathology - and therapy. The place of chemotherapy as well as that of surgery are largely detailed, thus placing the urologist at the heart of the multidisciplinary team taking care of these patients. Quality of life is also discussed by taking into account the impact of the treatment of these tumors on the fertility of these young patients.
Cancer du sein ; Compte rendu cours supérieur francophone de cancérologie, (Saint-Paul-de-Vence 13-15 Janvier 2005) = Breast cancer ; Report on the advanced French-language course in oncology, (Saint-Paul-de-Vence, January 13-15, 2005)
In January 2005, the 9th Cours de Saint-Paul-de-Vence, devoted to Breast Cancer, was dominated by the establishment of "Recommendations for Clinical Practice". The five subjects of these recommendations, such as the management of the axillary cavity, neo-adjuvant treatments, the management of patients whose tumor overexpresses HER2, adjuvant hormone therapy and finally adjuvant chemotherapy have been widely discussed. As in each course, certain essential fields were treated such as organized screening, conventional radiology and MRI, prognostic and predictive factors. Ductal cancers and lobular cancers have been compared in a remarkable way in three papers which were produced by the Saint-Cloud school. Data on in situ cancers have been updated. Finally, advice was given for the use of the various standards, whether local, regional or national.R2, l¹hormonothérapie adjuvante et enfin la chimiothérapie adjuvante ont été largement abordés.
Cancer Chemoprevention ; Vol.2 : Strategies for Cancer Chemoprevention
In Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention, leading chemopreventives investigators comprehensively describe the exciting methodologies that are accelerating progress in the chemoprevention field and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design.
Cancer
The last decade has seen a dramatic shift in anticancer drug research towards agents that aim to target selectively key regulatory and signaling processes known to drive tumorigenesis. A number of these newer agents have now been introduced into clinical practice. This volume reviews advances in cancer chemotherapy research over the last 10 years and will be of interest to scientists engaged in drug research in the pharmaceutical industry, biotechnology and startup companies, academia and government institutions. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs, including anti-hormonal therapy, growth factor inhibition, survival signaling, cell cycle inhibition, anti-angiogenics and anti-nvasives. Each chapter aims to cover the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.
Calixarenes in the Nanoworld
Calixarenes have been widely exploited in all areas of supramolecular chemistry over the past three decades and many recent developments have concerned their applications in the production of chemical entities with the dimensions of nanometres, as in "nanochemistry".Calixarenes in the Nanoworld Relates calixarenes to nanochemistry – key information for industries engaged in the production of high-tech materials. Provides a timely review of both what is known and the exciting prospects provided by calixarenes, Contains several review articles which define the importance of calixarenes as reagents in nanochemistry.
Calculus of variations and nonlinear partial differential equations : With a historical overview by Elvira Mascolo : Lectures given at the C.I.M.E. Summer School held in Cetraro, Italy, June 27 - July 2, 2005
This volume provides the texts of lectures given by L. Ambrosio, L. Caffarelli, M. Crandall, L.C. Evans, N. Fusco at the Summer course held in Cetraro (Italy) in 2005. These are introductory reports on current research by world leaders in the fields of calculus of variations and partial differential equations. The topics discussed are transport equations for nonsmooth vector fields, homogenization, viscosity methods for the infinite Laplacian, weak KAM theory and geometrical aspects of symmetrization. A historical overview of all CIME courses on the calculus of variations and partial differential equations is contributed by Elvira Mascolo.
Calcolo stocastico per la finanza = Stochastic Calculation for Finance
Offers an introduction to the mathematical, probabilistic and numerical methods that are the basis of the models for the valuation of derivative instruments, such as options and futures, dealt with in modern financial markets. The book is aimed at readers with scientific training, wishing to develop skills in the field of stochastic calculus applied to finance.
CADD and informatics in drug discovery
Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .
Cable stayed bridges, Second ed.
The cable stayed bridge is an elegant, economical and efficient structure. Virtually unknown 40 years ago, these bridges have become increasingly important as their properties have been more fully understood. They have recently proved to be highly cost-effective for short to medium spans. The second edition of this extremely popular book has been updated and enhanced to cover the rapid technological progress in this field. Exceptionally well illustrated, the book examines all aspects of the design of cable stayed bridges.
C*-algebras and Elliptic Theory
This volume contains the proceedings of the conference on "C*-algebras and Elliptic Theory" held in Bedlewo, Poland, in February 2004. It consists of original research papers and expository articles focussing on index theory and topology of manifolds.The collection offers a cross-section of significant recent advances in several fields, the main subject being K-theory (of C*-algebras, equivariant K-theory). A number of papers is related to the index theory of pseudodifferential operators on singular manifolds (with boundaries, corners) or open manifolds. Further topics are Hopf cyclic cohomology, geometry of foliations, residue theory, Fredholm pairs and others.
By-catch Reduction in the Worlds Fisheries
This book comes after several decades of outstanding and successful research that has helped ameliorate some of the most important and controversial fisheries issues in the world – those associated with the unwanted wastage of fish from by-catch and discarding. The 8 chapters encompass contributions from 27 of the world’s leading experts in by-catch reduction. They take the reader through most aspects of the field at a variety of scales and viewpoints. They examine the methodologies used to develop by-catch reduction techniques and provide new avenues for assisting and broadening such work. Case studies are provided that encompass most of the world’s fishing techniques and regions.
Business statistics : Communicating with numbers
Takes a comprehensive and contemporary approach that aims to bridge the gap between how statistics is taught and applied in the business world. this title not only prepares students in basic statistics but also gets them excited about further exploration of data analytics. the authors emphasize communicating with numbers rather than number crunching, through relatable case studies with relevant statistical methods and takeaways. this title incorporates timely examples from various fields, reinforces core features from previous editions, uses Excel and R to analyze data and solve problems, and includes new improvements, such as a revised chapter on data visualization, an exclusive chapter on logistic regression, and digital enhancements such as a big data capstone project with algorithmic exercises that span across multiple chapt.
Business process management Workshops ; Vol. 3812 : BPM 2005 International Workshops, BPI, BPD, ENEI, BPRM, WSCOBPM, BPS, Nancy, France, September 5, 2005. Revised Selected Papers
Six parallel Business Process Management workshops were held on September 5th, 2005,The topics of the workshops ranged from fundamental process modeling primitives to the recently emerged field of Web service choreography and orchestration, rep- sented in the “Workshop on Business Processes and Services” and the “Workshop on Web Service Choreography and Orchestration;” a topic which intersects the research fields of business process management and Web services.
Business cycle dynamics : Models and tools
Business cycle theory has been one of the fastest growing fields in modern nonlinear economic dynamics. The book is centered around models of multiplier-accelerator type, emerging from Samuelson's seminal work, later developed into nonlinear formats by Hicks and Goodwin. These models left open ends, as the tools then available did not permit more systematic analysis.
Business criminal law: A primer for management and economics
Deals with business criminal law from the perspective of Germany, Austria, Liechtenstein and Switzerland. It primarily addresses students in business and economics (master's programme) as well as business practitioners, but is also meant for lawyers and law students. As criminal law legislators exert considerable influence on economic life, raising and growing awareness in the area of criminal law seems compulsory for future managers and executives. This textbook approaches the legal field less normatively and rather in a practical and entrepreneurial way. Its contents are based on the master level class "Business Criminal Law
Bulk Metallic Glasses : An Overview
Bulk Metallic Glasses explores an emerging field of materials known as bulk metallic glasses. It summarizes the rapid development of these materials over the last decade and includes documentation on diverse applications of bulk metallic glasses; from structural applications to microcomponents. Some of the applications covered are pressure sensors, microgears for motors, magnetic cores for power supplies, and nano-dies for replacing next generation DVDs. The chapters cover current theories and recent research including an atomistic theory of local topological fluctuations, atomistic simulations, and unique microstructures of these amorphous materials. Other topics include glass formation, glass forming ability, and the underlying mechanisms and physical insights of these criteria. The mechanical deformation of bulk metallic glasses, fatigue, fracture, and corrosion behaviors of these materials are also reviewed.
Bulk Fill Resin Composites in Dentistry : A Clinical Guide
Dedicated to all relevant aspects of bulk fill materials and their uses in clinical practice. Today, we count over 30 different bulk fill materials, which can be used in the dental clinic. The composition of bulk fill materials and their different modes of application for moderate to large direct resin restorations placement are explained in this book. It is written by a group of international specialists and allows the reader to evaluate available materials, learn predictable techniques and evaluate long term survival as well as future developments. The book covers all fields related to the history of bulk fill composites, their composition and physical properties, and a step by step guide to their successful clinical applications.
