الصفحة 9
الصفحة 9
Misbehaving Proteins : Protein (Mis)Folding, Aggregation, and Stability
Misfoldedaggregatedproteinoncewasconsideredasinterestingasyesterday’strash—a bothersome by-product of important and productive activities, to be disposed of and forgotten as quickly as possible. Yesterday’s trash has become today’s focus of cons- erable scienti?c interest for at least two reasons: (1) protein aggregates are at the core of a number of chronic degenerative diseases such as Alzheimer’s disease, and (2) - gregation poses signi?cant obstacles to the manufacture of safe, ef?cacious, and stable protein products. As interest in protein misfolding, aggregation, and stability has soared beyond the core group of traditional protein-folding scientists, and as substantial scienti?c progress in understanding and controlling protein misfolding has been achieved, the need to summarize the state of the art became manifest. Although there are many excellent texts and edited collections on protein structure and folding, these volumes tend to relegate protein misfolding and aggregation to a minor role. Review articles and books focused on the biological role of protein aggregates in diseases have been published recently.
Mining Equipment Reliability, Maintainability, and Safety
From its origins in the malachite mines of ancient Egypt, mining has grown to become a global industry which employs many hundreds of thousands of people. Today, the mining industry makes use of various types of complex and sophisticated equipment, for which reliability, maintainability and safety has become an important issue. Mining Equipment Reliability, Maintainability, and Safety is the first book to cover these three topics in a single volume.
Minimally Invasive Neurosurgery and Neurotraumatology
Neurotraumatology patients present an enormous challenge to society. Neuros- gical management of brain and spinal cord injury has been a frustrating area, as s- gical methods, especially in moderate and severe injuries, have been limited to control of brain and spinal compression, control of intracranial pressure with its expected effect on cerebral blood flow, and structural repair of the supporting structures (skull, spine, brain and spinal cord coverings). Achieving the best outcome for the neu- traumatology patient, however, requires much more than that.
Mind conversation = التنبؤ بالحروف العربية من خلال الإشارات الدماغية
Throughout history, humans have long dreamed of understanding what goes on inside the human mind—what people are thinking or feeling. It seemed like something from a far-off future or a magical realm. But now, thanks to amazing technology called EEG and BCI, this dream is turning into reality. EEG stands for electroencephalography. It's a way of listening to what the brain is up to by placing small sensors on or near the head. These sensors pick up tiny electrical signals produced by the brain's activity. It's like eavesdropping on the brain's conversations with itself. BCI, or Brain-Computer Interface, is like a bridge between the brain and machines. It lets the brain talk to devices or computers. This means people can control things without using their hands or voices. Our system takes advantage of EEG and BCI to create something helpful, a special mobile app. This app is designed for people who can't move their bodies, like those who are paralyzed. It helps them use their phones to express what they are thinking about.
Migration and Pandemics : Spaces of Solidarity and Spaces of Exception
This book discusses the socio-political context of the COVID-19 crisis and questions the management of the pandemic emergency with special reference to how this affected the governance of migration and asylum. The book offers critical insights on the impact of the pandemic on migrant workers in different world regions including North America, Europe and Asia.
Mid-Infrared Coherent Sources and Applications
Coherent sources of mid-infrared (mid-IR) radiation are of great interest for a wide range of scienti?c and technological applications from spectroscopy and frequency metrology to information technology, industrial process control, pho- chemistry, photobiology and photomedicine. The mid-IR spectrum, which may be de?ned as wavelengths beyond ?2µm, covers important atmospheric windows, and numerous molecular gases, toxic agents, air, water, and soil pollutants, c- ponents of human breath, and several explosive agents have strong absorption ?ngerprints in this region. The development of practical coherent solid-state sources in the mid-IR can thus provide indispensable tools for a variety of - plications in environmental monitoring and pollution control, detection of water and soil contaminants, food quality control, agriculture and life sciences, and n- invasive disease diagnosis and therapy through breath analysis.
Microsoft Dynamics NAV : Jump Start to Optimization
Mastering Microsoft Dynamics NAV for beginners and IT professionals: from jump start to optimization. This book covers general use and shows you how to tailor Microsoft Dynamics NAV to mirror your firm's unique needs. Learn skills that enable you to navigate and interpret the world of possibilities locked within the ERP system. Through easy, concrete examples, you will master the layered environment and be able to use and create reports, forms, import/export functions and more. This book gives you the basis you need to demand the best information infrastructure for your enterprise.
Microsoft .NET framework 2.0 web-based client development : MCTS self-paced training Kit (Exam 70-528)
Designed to help you make the most of your study time. Maximize your performance on the exam by learning to: * Create, trace, configure, and deploy Web applications * Integrate data into your application using Microsoft ADO.NET, XML, and data-bound controls * Implement forms authentication, impersonation, and login controls * Configure server controls and create custom Web controls * Use themes, user profiles, and Web parts for customizable, personalized Web sites * Manage server-side and client-side application state PRACTICE TESTS Assess your skills with practice tests on CD. You can work through hundreds of questions using multiple testing modes to meet your specific learning needs. You get detailed explanations for right and wrong answers?including a customized learning path that describes how and where to focus your studies. Your kit includes: * Official self-paced study guide. * Practice tests with multiple, customizable testing options and a learning plan based on your results. *400+ practice and review questions. * Case scenarios and lab exercises. * Microsoft Visual Basic and Visual C# code samples on CD.
Microprocessor 3 : Core concepts - hardware aspects
Calculation is the main function of a computer. The central unit is responsible for executing the programs. The microprocessor is its integrated form. This component, since the announcement of its marketing in 1971, has not stopped breaking records in terms of computing power, price reduction and integration of functions (calculation of basic functions, storage with integrated controllers). It is present today in most electronic devices. Knowing its internal mechanisms and programming is essential for the electronics engineer and computer scientist to understand and master the operation of a computer and advanced concepts of programming.
Microorganisms in Foods 6 : Microbial Ecology of Food Commodities
The second edition of Microorganisms in Foods 6: Microbial Ecology of Food Commodities is intended for those primarily in applied aspects of food microbiology. For 17 commodity areas it describes the initial microbial flora and the prevalence of pathogens, the microbiological consequences of processing, typical spoilage patterns, episodes implicating those commodities with foodborne illness, and measures to control pathogens and limit spoilage. The control measures are presented in a standardized format in line with international developments in risk management. A comprehensive index has also been added.
Microcontrollers in Practice
Stressing common characteristics and real applications of the most used microcontrollers, this practical guide provides readers with hands-on knowledge of how to implement three families of microcontrollers (HC11, AVR, and 8051). Unlike the rest of the ocean of literature on individual chips, Microcontrollers in Practice supplieS side-by-side comparisons and an overview that treats the systems as resources available for implementation. Packed with hundred of practical examples and exercises to foster mastery of concepts and details, the guide also includes several extended projects. By treating the less expensive 8-bit and RISC microcontrollers, this information-dense manual equips students and home-experimenters with the know-how to put these devices into operation.
The 8051 microcontroller and embedded systems
The Classical Period: Nineteenth Century Sociology Auguste Comte (1798-1857) on Women in Positivist Society Harriett Martineau (1802-1876) on American Women Bebel, August (1840-1913) on Women and Socialism Emile Durkheim (1858-1917) on the Division of Labor and Interests in Marriage Herbert Spencer (1820-1903) on the Rights and Status of Women Lester Frank Ward (1841-1913) on the Condition of Women Anna Julia Cooper (1858-1964) on the Voices of Women Thorstein Veblen (1857-1929) on Dress as Pecuniary Culture The Progressive Era: Early Twentieth Cent.
Microbial protein toxins
Since the initial establishment of Robert Koch’s postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and plants are extremely toxic and most of them developed remarkably "intelligent" strategies to enter, to penetrate and to finally kill a eukaryotic target cell by modifying or blocking essential cellular components. This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and biologically relevant toxin model systems. As a result, it significantly broadens our perspective on biochemical architecture and molecular ploy behind the lethal principles of pro- and eukaryotic toxins.
Micro-, Meso- and Macro-Dynamics of the Brain
This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The topics cover the most fascinating facets of neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory and mental illness, brain controlled robots, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Overall, this volume offers an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Methods of microarray data analysis IV
As studies using microarray technology have evolved, so have the data analysis methods used to analyze these experiments. The CAMDA conference plays a role in this evolving field by providing a forum in which investors can analyze the same data sets using different methods. METHODS OF MICROARRAY DATA ANALYSIS IV is the fourth book in this series, and focuses on the important issue of associating array data with a survival endpoint. Previous books in this series focused on classification (Volume I), pattern recognition (Volume II), and quality control issues (Volume III). In this volume, four lung cancer data sets are the focus of analysis. We highlight three tutorial papers, including one to assist with a basic understanding of lung cancer, a review of survival analysis in the gene expression literature, and a paper on replication. In addition, 14 papers presented at the conference are included. This book is an excellent reference for academic and industrial researchers who want to keep abreast of the state-of-the-art of microarray data analysis.
Methods for measuring greenhouse Gas balances and evaluating mitigation options in smallholder agriculture
This book provides standards and guidelines for quantifying greenhouse gas emissions and removals in smallholder agricultural systems and comparing options for climate change mitigation based on emission reductions and livelihood trade-offs. Globally, agriculture is directly responsible for about 11% of annual greenhouse gas (GHG) emissions and induces an additional 17% through land use change, mostly in developing countries. Farms in the developing countries of sub-Saharan Africa and Asia are predominately managed by smallholders, with 80% of land holdings smaller than ten hectares. However, little to no information exists on greenhouse gas emissions and mitigation potentials in smallholder agriculture.
Methods and Techniques for Cleaning-up Contaminated Sites
This publication is meant to foster links between groups facing challenges cleaning up contaminated sites through presentations that explore the problems currently being addressed and solutions that are emerging in the field.
Metastasis of Breast Cancer
The book has covered a broad range of topics in the metastasis of breast cancer, from genetics, biology to clinical management. Main topics include genetic control, biology, growth factors, cell adhesion, cell motility and invasion, natures of bone metastasis, sentinel node therapies, hormonal links, new biomarkers and detection of micrometastasis, and diagnosis The book also covers the current treatment options including surgical management, chemotherapy and hormonal therapies.
Metalliferous Sediments of the World Ocean : Fundamental Theory of Deep-Sea Hydrothermal Sedimentation
Dramatic advances in understanding global tectonics have been made in the last half century and the information and specific data acquired on the floor of the World Ocean by the scientific community probably has exc- ded that available in all previous time. With the benefit of new technology and advanced concepts in the earth sciences extensive exploration of the deep seabed became possible, and has been carried out in many parts of the world. Many features have been recognized and data recorded that are vital for understanding the fundamental processes that shape the earth=s surface and control the habitable environment. The data collected to date on the o- an floor and its physical environment greatly exceeds our understanding and appreciation of their fundamental importance in the earth sciences, and our ability to apply this knowledge effectively in improving our way of life.
Metalearning : Applications to Automated Machine Learning and Data Mining
This book as one of the fastest-growing areas of research in machine learning, metalearning studies principled methods to obtain efficient models and solutions by adapting machine learning and data mining processes. This adaptation usually exploits information from past experience on other tasks and the adaptive processes can involve machine learning approaches. As a related area to metalearning and a hot topic currently, automated machine learning (AutoML) is concerned with automating the machine learning processes. Metalearning and AutoML can help AI learn to control the application of different learning methods and acquire new solutions faster without unnecessary interventions from the user.
