الصفحة 9
الصفحة 9
Flavonoids as nutraceuticals
Flavonoids are well-known plant metabolites that have extraordinary properties that can be used for treating health issues. The pharmaceutical importance of flavonoids is due to their anti-depressant, anti-viral, anti-inflammatory, and antioxidant capacities. They are also of great importance when it comes to neuroprotection, cardiovascular disorders, and many types of cancer. Flavonoids are also easily available and produce less harmful side effects than some conventional therapeutics. This new volume examines the growing use of flavonoids for prevention and treatment of diseases and discusses their beneficial mechanisms. Chapters in the volume address diverse uses as anti-aging tools, as anti-inflammatory agents, for treating pregnancy-induced disorders, as a promising tool to combat infection of Covid-19, etc. The book explores their specific therapeutic antiviral potentials, the gene expression by flavonoids, and the role of flavonoids in agriculture.
Fitzpatrick's therapeutics : A clinician's guide to dermatologic treatment
It is the gold-standard textbook in dermatology and is designed to be read by practicing clinicians, medical trainees, and skin scientists when they want a complete and extensive overview of any dermatologic topic. Although comprehensive, the patient management sections in Fitzpatrick’s Dermatology are not presented in a format that facilitates easy and quick access for busy practicing clinicians who want to review treatment options at the bedside. The idea for Fitzpatrick’s Therapeutics arose to fill this gap.
Fitofarmacovigilanza : Vigilanza sulla sicurezza dei prodotti fitoterapici = Phytopharmacovigilance: Monitoring the safety of phytotherapeutic products
The use of herbal medicines is now widespread in large sections of the population to solve both acute and chronic problems, both trivial and very serious, and for health purposes. We know that phytotherapics can be obtained without a prescription, and that they are found, as well as in pharmacies, also in herbal medicine and supermarkets as food supplements. It is therefore essential to monitor the safety of these products through phytopharmacovigilance, which requires in-depth knowledge about the nature of the phytotherapic, its chemical components and the way in which it was prepared and used. Doctors, pharmacists, herbalists, and consumers themselves will find in this manual useful information on adverse reactions (ADRs) from herbal medicines; the industries of the herbal sector, and above all the legislator and the bodies responsible for control, will find incentives to improve the safety of use of these natural drugs.
Filgrastim in clinical oncology : Guarding against neutropenia
Granulocyte colony-stimulating factor (G-CSF) has driven the attention of researchers as a therapeutic agent for curing patients suffering from neutropenia. Despite the successful use of G-CSF, it currently requires daily injections, which are inconvenient, expensive, and distressing for children. Therefore, an alternative strategy for using G-CSF for treatment is needed. Understanding the G-CSF structure, expression, mechanism of action, and how it induces neutrophils mobilization is crucial to producing promising cancer therapy. The ability of G-CSF to mobilize hematopoietic stem cells from the bone marrow into the blood circulation was consequently exploited and altered the practice of hematopoietic stem cell transplantation.
Fibrogenesis : Cellular and molecular basis
Fibrogenesis: Cellular and Molecular Basis is the first volume to provide a synopsis of the rapid progress that has been documented in fibrogenesis over last couple of years, which significantly enhanced our understanding of the pathomechanisms of fibrotic diseases. Knowledge on molecular and celluar basis of fibrotic diseases has provided opportunities to develop selective and effective gene-based therapeutic options.
Feldman and Pike's vitamin D; Vol. 2 : Health, disease and therapeutics
Covers the evidence for new roles of vitamin D, ranging from organ transplantation to cancer, diabetes, inflammatory bowel disease, multiple sclerosis, and renal disease. The coverage is appropriately broad, drawing on aspects of internal medicine, pediatrics, nutrition, orthopedics, oncology, neurology, obstetrics and gynecology, and immunology, as well as, new areas for vitamin D including sports medicine, opthalmology, veterinary medicine and ICU care – including COVID-19. Clinical researchers will gain a strong understanding of the molecular basis for a particular disease and better understand future directions for research in this still-growing field.
Feldman and Pike's vitamin D; Vol. 1 : Biochemistry, physiology and diagnostics
Presents a comprehensive review of the multi-faceted actions of vitamin D relating both to skeletal and extra-skeletal action. Researchers from all areas of vitamin D will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic and proteomic insights into the mechanisms of disease.
Fecal Incontinence : Diagnosis and Treatment
Fecal incontinence is a frequent, distressing condition that has a devastating impact on patients’ lives. However, patients are typically embarrassed and reluctant to acknowledge this disability, so they relinquish the possibility of being cured and remain socially isolated. Since fecal incontinence may result from various pathophysiological situations, an accurate diagnostic work-up of each patient is fundamental. Today, a wide range of therapeutic options is available, but making the correct choice is pivotal to the successful management of this condition. This book is aimed at all physicians involved in the assessment and treatment of fecal incontinence. Its main purpose is to review the latest advances in the epidemiologic, socio-economic, psychologic, diagnostic, and therapeutic aspects of fecal incontinence, in order to establish guidelines for effective treatment.
Fatty acids
Fatty acid metabolism, including the de novo synthesis, uptake, oxidation, and derivation of fatty acids, plays several important roles at cellular and organ levels. Recent studies have identified characteristic changes in fatty acid metabolism in idiopathic pulmonary fibrosis (IPF) lungs, which implicates its dysregulation in the pathogenesis of this disorder. Here, we review the evidence for how fatty acid metabolism contributes to the development of pulmonary fibrosis, focusing on the profibrotic processes associated with specific types of lung cells, including epithelial cells, macrophages, and fibroblasts. We also summarize the potential therapeutics that target this metabolic pathway in treating IPF.
FASTtrack : Pharmaceutics - dosage form and design
Discusses an array of major dosage forms that are commonly encountered by pharmacists in professional practice. Essential information concerning the formulation of these dosage forms is delivered in a format that will aid your understanding and remove the complexities of the various topics.
Extra-coronal restorations : Concepts and clinical application
A clinical guide to contemporary materials and techniques for the restoration of individual teeth and implants. It fully reflects the important developments in the field over the past 15 years, including in particular the shift away from wholesale use of crowns towards adhesive dentistry and less invasive extra-coronal restorations. The book opens by considering the principles and evidence base relating to the longevity of restorations of teeth and implants. Importantly, it explains how to ensure "a healthy start" and manage future risks. Material choice and aesthetic issues are then discussed, before all aspects of the planning and provision of extra-coronal restorations are examined in depth. The coverage also includes the adaptation of crowns to existing partial dentures. In line with modern dental education, each chapter begins with clinically relevant learning objectives, and helpful clinical tips are highlighted.
Exploring medicinal orchids
Orchids are fascinating ornamental flowers with a huge market both as cut flowers and potted plants, but they are also used in the traditional medicine system as they can be rich in phytochemicals with exceptional medicinal properties. This book, Exploring Medicinal Orchids, is a comprehensive guide for medicinally important orchids, their diversity, and their use in traditional and folk medicines. It presents information on secondary metabolites of medicinally active orchid species, pharmaceutical and medicinal applications, and describes advanced techniques of biotechnology in the conservation of medicinal orchids.
Exosomes based drug delivery strategies for brain disorders
Provides a comprehensive overview of the role of exosomes in brain diseases, including stroke, multiple sclerosis, Parkinson's disease, Alzheimer's disease, epilepsy, and depression. It covers the basics of exosome biogenesis, composition, and synthesis, as well as the therapeutic potential of exosomes in brain disorders. The correlation between exosomes and neuroinflammation, the challenges of using exosomes as a novel carrier, and engineered exosomes to deliver therapeutic protein are covered well in this book. Use of radiolabelled exosomes as a diagnostic tool and the toxicity studies of exosomes with potential overcome approaches. It is an essential resource for researchers, clinicians, and healthcare professionals working in the field of exosome research, especially on its applications in brain disorders.
Evaluation of the use of medicine plants in cancer treatment
Turmeric (Curcuma longa) and ginger (Zingiber officinale) have been widely studied for their potential anticancer effects, primarily due to the bioactive compounds curcumin and gingerol. Both compounds exhibit significant therapeutic properties, including anti-inflammatory, antioxidant, pro-apoptotic, and anti-angiogenic activities, which target key pathways implicated in cancer progression, such as NF-κB, STAT-3, and mTOR. Through these mechanisms, curcumin and gingerol inhibit tumor growth, reduce metastasis, and enhance the efficacy of conventional cancer treatments.
Euthanasia : Searching for the full story : Experiences and insights of Belgian doctors and nurses
This book has been written by ten Belgian health care professionals, nurses, university professors and doctors specializing in palliative care and ethicists who, together, raise questions concerning the practice of euthanasia.
Essentials of pharmacodynamics and drug action
Provides a comprehensive exploration of the dynamic field of pharmacology and its fundamental principles. It delves into the intricate interactions between drugs and the human body, focusing on pharmacokinetics, which explains the dynamics of drug actions in the body, and pharmacodynamics, which uncovers the mechanisms through which drugs exert their effects. The book also emphasizes the crucial aspects of therapeutics and gene-based therapy, shedding light on modern approaches to disease treatment.
Essentials of human disease in dentistry
Takes an integrated approach to dentistry and how it relates to general medicine, surgery, pharmacology, therapeutics, pathology and microbiology.
Essential practical prescribing
Designed to support lecture series or themes on core topics within the health sciences. See www.wileyessential.com for further details. Contains a range of learning methods within each chapter including: key topics, learning objectives, case studies, DRUGS checklists, ‘Top-Tips’, advice on guidelines and evidence, and key learning points Uses patient histories to set the scene and enhance the clinical emphasis Offers examples of correctly completed drug charts throughout Is an ideal companion for Prescribing Safety Assessment (PSA) preparation
Essential oils for dental health : A holistic guide to oral care and treatment
Explores the benefits of and best methods of use for well-known dental care oils such as peppermint, tea-tree, and clove as well as the lesser known oral benefits of oils like cinnamon, manuka, and oregano. Offers many simple practical techniques to easily incorporate essential oils into your daily oral care routine. Includes recommended oil mixtures targeted to alleviate specific dental and oral ailments, such as periodontitis, oral herpes, ulcers, teething, dry mouth, bad breath, teeth grinding, and toothache.
Essential oils as antibacterial agents
An alarm increase in the rate of emerging of resistant bacteria have been causing a great public concern worldwide. This problem of increasing resistance has necessitated the search for safe and effective factors that may be used to treat persistent bacterial infections or modify the currently available antibiotics. An experimental approach, using agar diffusion method was used to estimate the antibacterial properties of 5 essential oils (cinnamon, clove, peppermint, rosemary and thyme) each one individually, in pure and commercial form, against 3 of the bacterial strains that cause common skin infections which are gram negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and gram positive bacteria (Staphylococcus aureus), obtained from clinical sources. Only two of the commercial oils had an antibacterial effect on both gram negative bacteria (E. coli) and gram positive bacteria (S. aureus) and in lesser extent on gram negative bacteria (P. aeruginosa).synergy.
