الصفحة 86
الصفحة 86
Bioreactors for Tissue Engineering : Principles, Design and Operation
This volume addresses the issue of mechanical conditioning of the tissue, and describes the use of techniques such as MRI for monitoring tissue growth. It also deals with the application of bioreactor technology to tissue engineering products.
Bioproducts From Canadas Forests : New Partnerships in the Bioeconomy
For the first time, this opportune book provides a comprehensive treatment of the many innovative, non-timber bioproducts that may be derived from Canada’s vast forests, including their potential economic, social and environmental impacts. It also offers a balanced discussion of the technological, policy and regulatory issues surrounding the emerging global bioeconomy. This book will not only be of interest to Canadian forestry professionals and entrepreneurs, but also to those interested in the contribution of forestry to the bioeconomy worldwide.
Biophysical Techniques in Photosynthesis ; Vol. II
Since the first volume on Biophysical Techniques in Photosynthesis Research, published in 1996, new experimental techniques and methods have been devised at a rapid pace. The present book is a sequel which complements the first volume (Volume 3 in the Series) by providing a comprehensive overview of the most important new techniques developed over the past ten years, especially those that are relevant for research on the mechanism and fundamental aspects of photosynthesis. The contributions are written by leading scientists in their field. The book has 5 sections: Imaging; Structure; Optical and laser spectroscopy; Magnetic resonance; Theory. Each chapter describes the basic concepts of the technique, practical applications and scientific results. Possibilities and limitations from a technical as well as a scientific point of view are addressed, allowing the reader not only to recognize the potential of a particular method for his/her own quest, but also to assess the resources that are required for implementation. The book is intended for use by graduate students and researchers in photosynthesis as well as in (bio)physics, (bio)chemistry and biology in general.
Biophysical characterization of functional peptides
Presents reproducible and step-by-step procedures for the peptide synthesis, their characterization and applications. The volume includes an introductory section on in silico modelling of new peptide molecules, Molecular Dynamics Simulations, Docking, Electrostatic fingerprinting of peptides, and other modelling tools for peptide designing and optimization. Further, it covers protocols for the solid phase peptide synthesis, chromatographic and mass spectrometric characterization of peptides. Importantly, it covers methods for biophysical characterizations of peptides for their potential applications as drug delivery vehicles, peptide nano-assembly, bionanocatalysis, protein aggregation diseases, and peptide-based anti-bacterial.
Biophysical Aspects of Transmembrane Signaling
Transmembrane signaling is one of the most significant cell biological events in the life and death of cells in general and lymphocytes in particular. Until recently biochemists and biophysicists were not accustomed to thinking of these processes from the side of a high number of complex biochemical events and an equally high number of physical changes at molecular and cellular levels at the same time. Both types of researchers were convinced that their findings are the most decisive, having higher importance than the findings of the other scientist population. Both casts were wrong. Life, even at cellular level, has a number of interacting physical and biochemical mechanisms, which finally build up the creation of an "excited" cell that will respond to particular signals from the outer or inner world.
Biophotonics and Coherent Systems in Biology
Biophotonics and Coherent Systems in Biology offers a timely research volume derived from papers submitted at the 3rd International Alexander Gurwitsch Conference. Biophotonics and Coherent Systems in Biology covers the major aspects of modern biophotonics and related biological and biophysical problems of interest to researchers today.Key topics include: Coherency of biophoton emission and its related physical and biological properties , Biological effects of microwaves, Photon emission from living samples, starting from human bodies up to cell cultures, Fundamental role of water in bioenergetics and the influence of electromagnetic fields upon hydrophobic-hydrophilic balance
Biophotonics ; Optical science and engineering for the 21st century
Biophotonics: Optical Science and Engineering in the 21st Century serves as an ideal aid to the research and development of these areas integrating light, photonics, and biological systems.Key topics include: Fluctuation Correlation Spectroscopy in Cells: Determination of Molecular Aggregation ,Using GFP and FRET Technologies for Studying Signaling Mechanisms of Apoptosis in a Single Living Cell, Study on Protein-Protein Interaction in Single Living Cells, Functional Optical Coherence Tomography: Simultaneous In Vivo Imaging of Tissue Structure and Physiology, Imaging –Photo- and Sonodynamic Diagnosis of Cancer Mediated by Chemiluminescence Probes, Biophotonic Analysis of Spontaneous Self-Organizing Oxidative Processes in Aqueous Systems, Biophoton Emission and Defense Systems in Plants
Biophotonics
More profound understanding of the nature of light and light-matter interactions in biology has enabled many applications in the biology and medical fields. So a new discipline is born, namely biophotonics. The aim of this book is to review the current state-of-the-art of the field by means of authoritative chapters written by the world leaders of the respective fields. Biosensors, biochips, optical tomography, optical microsurgery, photodynamics therapy, bioactivation of gene, photobiology of skin, and nanobiophotonics are each introduced and recent advances presented. This book will be useful not only to physicians, biologists, physicists, chemists, materials scientists, and engineers but also to graduate students who are interested in these rapidly developing fields.
Biopharmaceutics applications in drug development
This book introduces fundamental concepts, methods, and advances in the areas of dissolution, absorption, and permeability and their key applications in dosage form performance. Case studies are used to discuss the applications of biopharmaceutic strategies in the development of successful drugs, with a specific focus on the applications of biopharmaceutic strategies in the development of successful drugs. The book presents an integrated view in linking pharmaceutic to the biological consequences of drug products and leverages those for decision making in drug development.
Biopharmaceutical manufacturing progress, trends and challenges
Source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation.
Biopharmaceutical drug design and development
Biopharmaceutical Drug Design and Development, Second Edition, updates the widely successful first edition, published in 1999. This new, expanded edition investigates the dozens of new biopharmaceutical drugs that have become available since the publication of the first edition. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, such as bioinformatics, DNA microarrays, transgenics, therapeutic gene delivery, stem cells, nucleic acid-based therapeutics, and macromolecular drug delivery. Authors also study pharmacogenetics in the clinic and changes in biologic drug approval at the FDA. Biopharmaceutical Drug Design and Development, Second Edition, is a worthy sequel in the discussion on the dynamic, exciting field of biotechnology.
BioPaceMaking
The development of a bio-engineered pacemaker is of substantial clinical and also scientific interest because it promises to overcome several limitations of electronic pacemakers. Moreover it may answer the longstanding question of whether the complex structure of the sinus node is indeed a prerequisite for reliable pacemaking, or simpler structures might work as well. This book gives an overview of the current state-of-the-art of creating a bio-engineered pacemaker. It shows the approaches to develop of genetic and cell-based engineering methods suitable to implement them with safety and stability. It also illuminates the problems that need to be solved before bio-pacemaking can be considered for clinical use.
Bioorganometallic Chemistry
Bioorganometallic Chemistry has become a mature area of science and is comprehensively covered by leading experts in this book. Naturally occuring bioorganometallic complexes, such as vitamin B12 and recently discovered iron and nickel hydrogenases, including a possible role of the latter in the geochemical theory of the origin of life, are considered.
Bionanotechnology : Proteins to Nanodevices
Bionanotechnology is the key integrative technology of the 21st century and aims to use the knowledge, gathered from the natural construction of cellular systems, for the advancement of science and engineering. Investigating the topology and communication processes of cell parts can lead to invention of novel biological devices with exciting applications. Though microscale to nanoscale research offers an excellent space for the development of futuristic technologies, a number of challenges must be overcome. Due to paucity of a dedicated literature on the protein based nanodevices we bring you this monograph that combines collective research works of scientists probing into this fascinating universe of bionanotechnology. The monograph has been written with an aim of surveying engineering design principles of biomolecular nanodevices, prototype nanodevices based on redox proteins, bacteriorhodopsins and natural fibers, and touching upon the future developments in the field.
BioNanoFluidic MEMS
BioNanoFluidic MEMS explains nanofabrication and nanomaterials synthesis suitable for the development of biosensors. The fundamentals initiate an awareness for engineers and scientists who would like to develop and implement novel biosensors for various applications. In addition, the material covered includes: BioNanoFluidic MEMS connection between the interdisciplinary nature of BioNanoFluidics and MEMS BioNanoFluidics and sensor technology including Micro-Mechanical Sensors and Chemical Sensor Technologies ands-on steps for implementation of biosensor fabrication including a discussion of the clean room lithography process and etching, microsensor systems lamination, PDMS moulding, parylene deposition, and others Interconnection between the interdisciplinary nature of BioNanoFluidics and MEMS BioNanoFluidics and sensor technology including Micro-Mechanical Sensors and Chemical Sensor Technologies
Biomining
Biomining is the biotechnology that uses microorganisms to recover metals, in particular copper and gold, from ores and concentrates. Having developed from a very simple operational (in terms of both engineering and biology) process, biomining has developed into a multifaceted technology, to the extent that many of the largest industrial stirred tanks and heaps throughout the world are employed for bioprocessing minerals. This book has a strong applied approach and describes emerging and established industrial processes, as well as the underlying theory of the process, and the biology of the microorganisms involved. Chapters have been written by personnel from leading biomining companies, consultants and internationally recognized researchers and academics
Biomineralization II : Mineralization Using Synthetic Polymers and Templates
In nature, biological organisms produce mineralized tissues such as bone, teeth, diatoms, and shells. Biomineralization is the sophisticated process of production of these inorganic minerals by living organisms. Construction of organic–inorganic hybrid materials with controlled mineralization analogous to those produced by nature has recently received much attention because it can aid in understanding the mechanisms of the biomineralization process and development of biomimetic materials processing. The biomineralization processes use aqueous solutions at temperatures below 100 ◦C and no toxic intermediates are produced in these systems. This series presents critical reviews of the present position and future trends in modern chemical research. The short and concise reports on chemistry are each written by world renowned experts. This series is still valid and useful after 5 or 10 years.
Biomineralization I : Crystallization and Self-Organization Process
The five chapters of Biomineralization, volume 1, provide a bridge between the mineralogy and the organic substrates that enable the mineral formation by organisms in nature and under laboratory conditions. The book is a most useful reference for all concerned with biomineralization and biogenic minerals.In nature, biological organisms produce mineralized tissues such as bone, teeth, diatoms, and shells. Biomineralization is the sophisticated process of production of these inorganic minerals by living organisms. Construction of organic–inorganic hybrid materials with controlled mineralization analogous to those produced by nature has recently received much attention because it can aid in understanding the mechanisms of the biomineralization process and development of biomimetic materials processing.
Biomineralization : From molecular and nano-structural analyses to environmental science
Over the past 45 years, biomineralization research has unveiled details of the characteristics of the nano-structure of various biominerals; the formation mechanism of this nano-structure, including the initial stage of crystallization; and the function of organic matrices in biominerals, and this knowledge has been applied to dental, medical, pharmaceutical, materials, agricultural and environmental sciences and paleontology. As such, biomineralization is an important interdisciplinary research area, and further advances are expected in both fundamental and applied research.
Biomimicry for Optimization, Control, and Automation
In this book, we focus onhowtousebiomimicryof the functionaloperationofthe “hardwareandso- ware” of biological systems for the development of optimization algorithms and feedbackcontrolsystemsthatextendourcapabilitiestoimplementsophisticated levels of automation. The primary focus is not on the modeling, emulation, or analysis of some biological system. The focus is on using “bio-inspiration” to inject new ideas, techniques, and perspective into the engineering of complex automation systems. There are many biological processes that, at some level of abstraction, can berepresentedasoptimizationprocesses,manyofwhichhaveasa basicpurpose automatic control, decision making, or automation.
