الصفحة 83
الصفحة 83
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Liver Immunology : Principles and Practice

parasitic and viral infections of the liver, autoimmune liver disease, alcoholic and nonalcoholic fatty liver diseases, and transplantation in an easy-to-read and thorough format. Authors also address the key issues that have arisen in this field in recent years, including physiological roles of hepatocytes, sinusoidal lining cells, activated macrophages (Kupffer cells), cholangiocytes and stellate cells, and their modulation of T cells, natural killer (NK) cells and NKT cells.

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Literature-based Discovery

When Don Swanson hypothesized a connection between Raynaud’s phenomenon and dietary fish oil, the field of literature-based discovery (LBD) was born. During the subsequent two decades a steady stream of researchers have published articles about LBD and the field has made steady progress in laying foundations and creating an identity. LBD is an inherently multi-disciplinary enterprise where collaborations between the information and biomedical sciences are readily encountered. It is the hope and intention that this volume will plant a flag in the ground and inspire new researchers to the LBD challenge.

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Listeria Monocytogenes : Pathogenesis and Host Response

This comprehensive volume, written by experts in the field, includes concise and timely reviews of Listeria monocytogenes, one of the most intensively studied bacterial pathogens. Listeria monocytogenes is the cause of listeriosis, a potentially fatal disease that arises from the consumption of contaminated food. During the past two decades, studies of this organism have uncovered a wealth of information on its virulence factors, its genome organization, and its interactions with host cells and the immune system.

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Liposomes as Drug Carriers

Patients have recently suffered from the side effects of a large number of drugs and from the weak pharmacological effect, due to the biokinetics and the difficulty of delivering the drug to the targeted cells, which negatively affected the therapeutic efficacy, creating an opportunity to discover nanometric carriers to load the active drug substances, so we covered in this research the most famous and widely used nanocarriers which are liposomes. We touched in some detail its composition, types, the relationship of structure to influence, methods of preparation, its delivery mechanism for the drug, and at the end of the research, we attached various applications in the field of therapeutic diagnostics and its role in cosmetics, cancers and many other fields.

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Linear Programming : Foundations and Extensions

Linear Programming: Foundations and Extensions is an introduction to the field of optimization. The book emphasizes constrained optimization, beginning with a substantial treatment of linear programming, and proceeding to convex analysis, network flows, integer programming, quadratic programming, and convex optimization. The book is carefully written. Specific examples and concrete algorithms precede more abstract topics. Topics are clearly developed with a large number of numerical examples worked out in detail.

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Linear and Generalized Linear Mixed Models and Their Applications

This book covers two major classes of mixed effects models, linear mixed models and generalized linear mixed models, and it presents an up-to-date account of theory and methods in analysis of these models as well as their applications in various fields. The book offers a systematic approach to inference about non-Gaussian linear mixed models. Furthermore, it has included recently developed methods, such as mixed model diagnostics, mixed model selection, and jackknife method in the context of mixed models.

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Linear and Generalized Linear Mixed Models and Their Applications

This book covers two major classes of mixed effects models—linear mixed models and generalized linear mixed models—and it presents an up-to-date account of theory and methods in analysis of these models as well as their applications in various fields. It offers a systematic approach to inference about non-Gaussian linear mixed models. Furthermore, it discusses the latest developments and methods in the field, incorporating relevant updates since publication of the first edition. These include advances in high-dimensional linear mixed models in genome-wide association studies (GWAS), advances in inference about generalized linear mixed models with crossed random effects, new methods in mixed model prediction, mixed model selection, and mixed model diagnostics.

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Limits to the European Union’s Normative Power in a Post-conflict Society : EULEX and Peacebuilding in Kosovo

Investigates the EU’s peacebuilding activities in that country, in the light of the normative power theory in the post-conflict setting and peacebuilding theory. Ten years after the massive engagement of the EU in the country torn by war, the authors critically assess the effects of the EU projecting its normative power – the enforcement of its standards, ‘good’ or ‘bad’ – through the EULEX mission, taking into consideration also the local aspects, so far neglected in this field of research. Inspecting thoroughly the EULEX activities in the police, customs and judiciary sector.This open access book offers a comprehensive assessment of the EULEX mission, based on two Horizon2020 research projects: IECEU - Improving the Effectiveness of Capabilities in EU Conflict Prevention, and KOSNORTH – The European Union and its Normative Power in a Post-conflict Society: A Case Study of Northern Kosovo (Marie Sklodowska-Curie Individual Fellowship).

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Limit Cycles of Differential Equations

Contains the lecture series originally delivered at the "Advanced Course on Limit Cycles of Differential Equations" in the Centre de Recerca Matemàtica Barcelona in 2006.The topics covered are the center-focus problem for polynomial vector fields, and the application of abelian integrals to limit cycle bifurcations. Both topics are related to Hilbert's sixteenth problem. In particular, the book will be of interest to students and researchers working in the qualitative theory of dynamical systems.

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Light Scattering Reviews 3 : Light Scattering and Reflection

Ddevoted to modern knowledge and milestones in both experimental and theoretical techniques related to light scattering and radiative transport problems. It will consist of 3 parts comprising 11 contributions written by world leading experts in their respective fields. The general focus of the book will be on remote sensing of geophysical media. The first part will be devoted exclusively to studies of single light scattering by particles of different shapes and chemical compositions. The first chapter will review in situ measurements of cloud optical characteristics like cloud extinction and phase function, with the emphasis on ice clouds. Chapter 2 will cover opitcally soft particles common in marine environments and bio-suspensions while Chapter 3 will describe numerical techniques applicable not only to isotropic but also to chiral and anisotropic mdia. The final chapter in this part will deal with spatial symmetries in light scattering problems.

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Light scattering by systems of particles : Null-field method with discrete sources : Theory and programs

Light Scattering by Systems of Particles comprehensively develops the theory of the null-field method, while covering almost all aspects and current applications. The "Null-field Method with Discrete Sources" is an extension of the Null-field Method (also called T-Matrix Method) to compute light scattering by arbitrarily shaped dielectric particles. This book incorporates FORTRAN programs and exemplary simulation results that demonstrate all aspects of the latest developments of the method. Worked examples of the application of the FORTRAN programs show readers how to adapt or modify the programs for their specific application.

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Light Scattering by Optically Soft Particles: Theory and Applications

Deals with a particular class of approximation methods in the context of light scattering by small particles. This class of approximations has been termed as eikonal or soft particle approximations. The eikonal approximation was studied extensively in the potential scattering and then adopted in optical scattering problems. In this context, the eikonal and other soft particle approximations pertain to scatterers whose relative refractive index compared to surrounding medium is close to unity. The study of these approximations is very important because soft particles occur abundantly in nature. For example, the particles that occur in ocean optics, biomedical optics, atmospheric optics and in many industrial applications can be classified as soft particles. This book was written in recognition of the long-standing and current interest in the field of scattering approximations for soft particles. It should prove to be a useful addition for researchers in the field of light scattering.

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Life System Modeling and Simulation; International Conference on Life System Modeling, and Simulation, LSMS 2007, Shanghai, China, September 14-17, 2007. Proceedings

The International Conference on Life System Modeling and Simulation (LSMS) was formed to bring together international researchers and practitioners in the field of life system modeling and simulation as well as life system-inspired theory and methodology. The arrival of the 21st century has been marked by a resurgence of research interest both in arriving at a systems-level und- standing of biology and in applying such knowledge in complex real-world appli- tions. Consequently, computational methods and intelligence in systems, biology, as well as bio-inspired computational intelligence, have emerged as key drivers for new computational methods. For this reason papers dealing with theory, techniques and real-world applications relating to these two themes were especially solicited.

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Life in the Universe : Expectations and Constraints

Energy, chemistry, solvents, and habitats -- the basic elements of living systems - define the opportunities and limitations for life on other worlds. This class-tested text examines each of these parameters in crucial depth and makes the argument that life forms we would recognize may be more common in our solar system than many assume. It also considers, however, exotic forms of life that would not have to rely on carbon as basic chemical element, solar energy as a main energy source, or water as primary solvent. Finally the question of detecting bio- and geosignature of such life forms is discussed, ranging from Earth environments to deep space. While speculative considerations in this emerging field of science cannot be avoided, the authors have tried to present their study with the breadth and seriousness that a scientific approach to this issue requires. They seek an operational definition of life and investigate the realm of possibilities that nature offers to realize this very special state of matter and avoid scientific jargon wherever possible to make this intrinsically interdisciplinary subject understandable to a broad range of readers.

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Life in Extreme Environments

Investigating life processes under extreme conditions can also bring clues for understanding and predicting ecosystems' responses to global changes. Furthermore, this area of research has a wide application potential in the fields of (bio)technoloty, chemical industry, pharmaceutics, biomedicine or cosmetics.

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Lie Groups : An Approach through Invariants and Representations

Lie groups has been an increasing area of focus and rich research since the middle of the 20th century. Procesi's masterful approach to Lie groups through invariants and representations gives the reader a comprehensive treatment of the classical groups along with an extensive introduction to a wide range of topics associated with Lie groups: symmetric functions, theory of algebraic forms, Lie algebras, tensor algebra and symmetry, semisimple Lie algebras, algebraic groups, group representations, invariants, Hilbert theory, and binary forms with fields ranging from pure algebra to functional analysis.

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Lidar : Range-Resolved Optical Remote Sensing of the Atmosphere

Written by leading experts in optical radar, or lidar, this book brings all the recent practices up-to-date and covers a multitude of applications, from atmospheric sciences to environmental protection. Its broad cross-disciplinary scope should appeal to both the experienced scientist and the novice in the field. The Foreword is by one of the early pioneers in the area, Herbert Walther.

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Lewis Fry Richardson : His Intellectual Legacy and Influence in the Social Sciences

A pioneer in meteorology and peace research and remains a towering presence in both fields. This edited volume reviews his work and assesses its influence in the social sciences, notably his work on arms races and their consequences, mathematical models, the size distribution of wars, and geographical features of conflict

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Les infections intra-abdominales aiguës = Acute intra-abdominal infections

Paradoxically, serious intra-abdominal infections are the forgotten ones in the world of infectious diseases. Paradoxical, because they are very common pathologies, affecting all age groups of the population and often life-threatening; paradoxical, because they concern many medical specialties through intensive care, gastroenterology, hepatology, imaging, infectious diseases, emergencies and surgery. Hence the need, thanks to an interdisciplinary collaboration, to publish a book in French bringing together all infectious abdominal pathologies, thus offering a synthesis of recent data from the literature in this field. This document should allow the various specialties concerned to find updates integrating the latest clinical, diagnostic and therapeutic data. Specialty interns and practitioners in the field will find something to establish an effective and up-to-date strategy for the management of patients with these pathologies, the high incidence of which and the severity of which is too often overlooked, it is important to remember.

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Les cancers ovariens = Ovarian cancers

Deals with ovarian cancers and their therapeutic management. Besides the epithelial tumors which are the most frequent, the rarer tumors, with attenuated malignancy, germ cells or of the ovarian stroma are also studied. Specialists from multiple backgrounds each deliver in their field the most recent knowledge on the fundamental aspects of the disease, its genetic, epidemiological and prognostic characteristics and its pathological peculiarities. Modern means of diagnosis are presented. The surgical technique, including laparoscopy, is detailed at the different stages of the disease. The therapeutic strategy aims to position the surgery and chemotherapy according to the stage. The current place of radiotherapy and isotopic therapies is indicated. Some more specific aspects are discussed, screening, lymph node dissection, the “second look”, intraperitoneal chemotherapy with or without hyperthermia, treatment of the elderly, monitoring after treatment… as well as the emergence of targeted therapies.

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