الصفحة 83
الصفحة 83
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Botanical drug products : Recent developments and market trends

Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the safety and effectiveness standards of a new drug in accordance. This book comprises a complete start-to-end process from drug-idea conception, to drug development process.

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Bone remodeling and osseointegration of implants

Provides an insight into the latest advances in bone fracture healing and remodeling algorithm and their incorporation into patient-specific finite element models and the use of machine learning and artificial intelligence to predict the bone regeneration and osseointegration process with a certain degree of accuracy. It also examines the applications of numerical models to simulate the fracture healing process, which may prove to be advantageous in determining the optimal mechanical-based treatment or reconstruction after an accident or illness.

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Bone densitometry for technologists

Radiologic technologists, nurse practitioners, physician assistants, and dedicated densitometry technologists can find new guidelines for bone density testing, new therapies for osteoporosis, and new treatment guidelines for osteoporosis, as well as new chapters on pediatric densitometry body composition assessments, and the use of skeletal morphometry in diagnosis and fracture risk prediction. The twelve appendices have also been updated to reflect the most current information available, including contacts for densitometry equipment manufacturers and organizations, guidelines for bone density testing and CPT codes, definitions of terms, and new conversion equations.

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Bonding in Microsystem Technology

Bonding in Microsystem Technology starts with descriptions of terminology, kinds of microsystems and market analysis. Followed by the presentation of mechanisms of wet etching, set of process parameters, description of micromachining methods, examples of procedures, process flow-charts and applications of basic micromechanical structures in microsystems are shown. Next, high-temperature, low temperature and room-temperature bonding and their applications in microsystem technology are presented. The following part of the book contains the detailed description of anodic bonding, starting from analysis of properties of glasses suitable for anodic bonding, and discussion of the nature of the process. Next all types of anodic bonding and sealing procedures used in microsystem technology are presented.

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Bond Portfolio Optimization

1 The tools of modern portfolio theory are in general use in the equity markets, either in the form of portfolio optimization software or as an accepted frame- 2 work in which the asset managers think about stock selection. In the ?xed income market on the other hand, these tools seem irrelevant or inapplicable. Bond portfolios are nowadays mainly managed by a comparison of portfolio 3 4 risk measures vis ¶a vis a benchmark. The portfolio manager’s views about the future evolution of the term structure of interest rates translate th- selves directly into a positioning relative to his benchmark, taking the risks of these deviations from the benchmark into account only in a very crude 5 fashion, i.e. without really quantifying them probabilistically. This is quite surprising since sophisticated models for the evolution of interest rates are commonly used for interest rate derivatives pricing and the derivation of ?xed 6 income risk measures.

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Body Sensor Networks

While the problems of long-term stability and biocompatibility are being addressed, several promising prototypes are starting to emerge for managing patients with acute diabetes, for treatment of epilepsy and other debilitating neurological disorders and for monitoring of patients with chronic cardiac diseases. Despite the technological developments in sensing and monitoring devices, issues related to system integration, sensor miniaturization, low-power sensor interface circuitry design, wireless telemetric links and signal processing still have to be investigated.

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Body and Practice in Kant

This book argues that this standard image of the great German philosopher is radically wrong. Not only does Kant reflect constantly upon the fact that human life is embodied, but the Critique of pure reason itself may be read as a critical reflection aimed at exploring some significant philosophical implications of this fact.

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Bluetooth based indoor location positioning system for mobile robot navigation

Positioning objects has been an important topic since it’s needed to locate people, guide them to a certain place, and assist companies and organizations with their assets management. Great applicational opportunities emerge based on the inquiry of Received Signal Strength Indicator (RSSI). In this research, a positioning system using Bluetooth RSSI is proposed for indoor applications. First, RSSI values are inquired multiple times and the average is taken at multiple points of different distances from the transmitters. Then the distance is determined by the variations of RSSI values respectively to distance variations. Finally, a triangulation algorithm is used to calculate the current location of the receiver.

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Blockchain and Other Emerging Technologies for Digital Business Strategies

Aims to explore the aspects of strategic leadership in a digital context together with the cyber-physical relationships whilst performing business activities. Furthermore, this book looks to investigate the interactions from both the organization strategy including the cross-functional actors/stakeholders whom are operating within the organization and the various characteristics of operating in a cyber secure ecosystem.

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Blockchain and crypto currency : Building a high quality marketplace for crypto data

This book contributes to the creation of a cyber ecosystem supported by blockchain technology in which technology and people can coexist in harmony. Blockchains have shown that trusted records, or ledgers, of permanent data can be stored on the Internet in a decentralized manner.

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Blind Speech Separation

This is the first book to provide a cutting edge reference to the fascinating topic of blind source separation (BSS) for convolved speech mixtures. Through contributions by the foremost experts on the subject, the book provides an up-to-date account of research findings, explains the underlying theory, and discusses potential applications. The individual chapters are designed to be tutorial in nature with specific emphasis on an in-depth treatment of state of the art techniques. Blind Speech Separation is divided into three parts:Part 1 presents overdetermined or critically determined BSS. Here the main technology is independent component analysis (ICA). ICA is a statistical method for extracting mutually independent sources from their mixtures. Part 2 addresses underdetermined BSS, where there are fewer microphones than source signals. Here, the sparseness of speech sources is very useful; we can utilize time-frequency diversity, where sources are active in different regions of the time-frequency plane.Part 3 presents monaural BSS where there is only one microphone. Here, we can separate a mixture by using the harmonicity and temporal structure of the sources. We can build a probabilistic framework by assuming a source model, and separate a mixture by maximizing the a posteriori probability of the sources.

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Blameworthy Belief : A Study in Epistemic Deontologism

Believing the wrong thing may sometimes have drastic consequences. The question as to when a person is not only ill-guided, but genuinely at fault for holding a particular belief is an important one: It touches upon the roots of our understanding of such notions as criminal negligence and moral responsibility. The answer to this question may influence the extent to which we are willing to submit each other to punishments ranging from mild resentment to harsh prison terms. This book presents an extensive effort to shed light on the conditions under which we may appropriately deem someone blameworthy for holding a particular belief. It regiments and unifies several debates within contemporary epistemology, ethics and legal scholarship. Finally, the book brings a new philosophical look on issues like our power to control beliefs and the extent and nature of foresight.

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Biotechnology of medicinal plants with antiallergy properties : Research trends and prospects

Covers critically investigated information on medicinal plants prioritized for their anti-allergy properties. It offers insights into strategies related to the distribution, mechanism of action, and assessment of antiallergic medicinal plants, and also delves into crucial aspects of modern biotechnological tools, addressing their implementation challenges, presenting innovative approaches through case studies, and exploring opportunities for nanotechnologies. These elaborated discussions aim to raise awareness and bridge the gap between human health and the biodiversity of antiallergic medicinal plants.

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Biotechnology for Fuels and Chemicals : The Twenty-Ninth Symposium

In Biotechnology for Fuels and Chemicals: The Twenty-Ninth Symposium, leading US and international researchers from academia, industry, and government exchange cutting-edge technical information and update current trends in the development and application of biotechnology for sustainable production of fuels and chemicals. This symposium emphasizes advances in biotechnology to produce high-volume, low-price products from renewable resources, while improving the environment. The major areas of interest include advanced feedstock production and processing, enzymatic and microbial biocatalysis, bioprocess research and development, opportunities in biorefineries, and commercialization of biobased products. International and domestic progress on producing liquid biofuels, especially ethanol and biodiesel, is highlighted, and related topics, including bioseparations and optimal integration of biochemical and thermochemical conversion technologies, are featured.

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Biostatistics and microbiology : A survival manual

This book presents a step-by-step manner that eliminates the greatest obstacle to the learner, which is applying the many processes that comprise a statistical method. The author counters the fear of statistical methods by describing early in the book a step-by-step procedure to perform a statistical method - a process that we will term "the six-step procedure." All of the testing will be performed adhering to six well-defined steps, which will greatly simplify the statistical process. Each step in the sequence must be completed before moving on to the next step.

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Bioremediation of Soils Contaminated with Aromatic Compounds

Environmental biotechnology, which was in its infancy in the early 80's, has evolved thanks to the revolution brought about by molecular biology. Multiple successes in the biological cleanup of civil and industrial wastewater and of hydrocarbon soil pollution, demonstrate the vast power of clean technologies. In addition, the buildup of information on the activities of microorganisms as catalysts in all sorts of natural, industrial and animal environments has flourished. There is a continuing realization of the critical role of microbial processes in biological, industrial and geological systems. Since environmental biotechnology has matured, it is ready to tackle bigger challenges: the scaling up of many bioremediation systems still in progress, the search for novel biocatalysts for industrial applications, the continuing effort against common human life-threatening processes such as antibiotic resistance, the accumulation of hormone-mimicking substances (endocrine disrupters), the deposition of air-borne pesticides in the environment and, the degradation of recalcitrant contaminants. These endeavors will help prevent the contamination of food chains, protect human life and allow for human activity and economic development that do not compromise environmental sustainabijity.

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Biophotonics ; Optical science and engineering for the 21st century

 Biophotonics: Optical Science and Engineering in the 21st Century serves as an ideal aid to the research and development of these areas integrating light, photonics, and biological systems.Key topics include: Fluctuation Correlation Spectroscopy in Cells: Determination of Molecular Aggregation ,Using GFP and FRET Technologies for Studying Signaling Mechanisms of Apoptosis in a Single Living Cell, Study on Protein-Protein Interaction in Single Living Cells, Functional Optical Coherence Tomography: Simultaneous In Vivo Imaging of Tissue Structure and Physiology, Imaging –Photo- and Sonodynamic Diagnosis of Cancer Mediated by Chemiluminescence Probes, Biophotonic Analysis of Spontaneous Self-Organizing Oxidative Processes in Aqueous Systems, Biophoton Emission and Defense Systems in Plants

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Biopharmaceutics applications in drug development

This book introduces fundamental concepts, methods, and advances in the areas of dissolution, absorption, and permeability and their key applications in dosage form performance. Case studies are used to discuss the applications of biopharmaceutic strategies in the development of successful drugs, with a specific focus on the applications of biopharmaceutic strategies in the development of successful drugs. The book presents an integrated view in linking pharmaceutic to the biological consequences of drug products and leverages those for decision making in drug development.

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Biopharmaceutical processing : Development, design, and Implementation of manufacturing processes

Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes covers bioprocessing from cell line development to bulk drug substances. The methods and strategies described are essential learning for every scientist, engineer or manager in the biopharmaceutical and vaccines industry. The integrity of the bioprocess ultimately determines the quality of the product in the biotherapeutics arena, and this book covers every stage including all technologies related to downstream purification and upstream processing fields. Economic considerations are included throughout, with recommendations for lowering costs and improving efficiencies.

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Biomining

Biomining is the biotechnology that uses microorganisms to recover metals, in particular copper and gold, from ores and concentrates. Having developed from a very simple operational (in terms of both engineering and biology) process, biomining has developed into a multifaceted technology, to the extent that many of the largest industrial stirred tanks and heaps throughout the world are employed for bioprocessing minerals. This book has a strong applied approach and describes emerging and established industrial processes, as well as the underlying theory of the process, and the biology of the microorganisms involved. Chapters have been written by personnel from leading biomining companies, consultants and internationally recognized researchers and academics

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