الصفحة 8
الصفحة 8
Guide to Biomolecular Simulations
Molecular dynamics simulations have become instrumental in replacing our view of proteins as relatively rigid structures with the realization that they were dynamic systems, whose internal motions play a functional role. Over the years, such simulations have become a central part of biophysics. Applications of molecular dynamics in biophysics range over many areas. They are used in the structure determination of macromolecules with x-ray and NMR data, the modelling of unknown structures from their sequence, the study of enzyme mechanisms, the estimation of ligand-binding free energies, the evaluation of the role of conformational change in protein function, and drug design for targets of known structures.
Groundwater : Resource evaluation, augmentation, contamination, restoration, modeling and management
The demand for water resources is increasing day by day due to ever increasing population, mostly from developing countries. This has resulted in abstracting more water from the subsurface stratum and forcing the water managers to manage the limited groundwater resources in a more scientific way, which in turn needs a more sophisticated way of assessing the underground resource and manage it optimally.
Grey information : Theory and practical applications
he book covers the latest advances in grey information and systems research, providing a state-of-the-art overview of this important field. Covering the theoretical foundation, fundamental methods and main topics in grey information and systems research, this book includes all the elementary concepts: basic principles, grey numbers and their operations, grey equations and matrices, operators of sequences and generations of grey sequences, grey incidence analysis, grey clusters and grey statistical evaluations, grey systems modeling, grey combined models, grey prediction, grey decisions, grey programming, grey input and output and grey controls, etc.
Green Chemistry and Sustainable Technology : Biological, Pharmaceutical, and Macromolecular Systems
Taking an interdisciplinary approach, this new volume brings together innovative research, new concepts, and novel developments in the application of new tools in green chemistry and sustainable technology. The diverse coverage includes chapters on ionic liquids as green solvents, an environmentally friendly approach to the synthesis and biological evaluation of α-aminophosphonate derivatives, the application of nanotechnology in biological sciences and green chemistry, ecofriendly polymers, the effect of global warming and greenhouse gases on environmental system, and more.
Graphics Recognition. Recent Advances and New Opportunities ; 7th International Workshop, GREC 2007, Curitiba, Brazil, September 20-21, 2007. Selected Papers
This book constitutes the thoroughly refereed post-proceedings of the 7th International Workshop on Graphics Recognition, GREC 2007, held in Curitiba, Brazil in September 2007.The 30 revised full papers presented together with a panel discussion report were carefully selected and improved during two rounds of reviewing and revision. The papers are organized in topical sections on technical documents, maps and diagrams understanding; symbol and shape description and recognition; information retrieval, indexing and spotting; sketching interfaces and on-line processing; feature and primitive analysis and segmentation; performance evaluation and ground truthing.
Grammatical Inference ; Algorithms and Applications : 9th International Colloquium, ICGI 2008 Saint-Malo, France, September 22-24, 2008 Proceedings
This book constitutes the refereed proceedings of the 9th International Colloquium on Grammatical Inference, ICGI 2008, held in Saint-Malo, France, in September 2008.The 21 revised full papers and 8 revised short papers presented were carefully reviewed and selected from 36 submissions. The topics of the papers presented vary from theoretical results of learning algorithms to innovative applications of grammatical inference, and from learning several interesting classes of formal grammars to applications to natural language processing.
Governance and performance of education systems
The proposed book is unique in that it brings together a wide range of disciplines and experience from several countries. What are possible models of governance? How do we measure their effects in terms of efficiency and equity? What type of contribution can financial and information systems make? How do we adapt the prevailing culture to the challenge of better performance? These are some of the concrete questions to which this book provides an answer.
Good pharmacovigilance practice (GVP) : Focus on risk mangement plan (RMP)
Pharmacovigilance which is the science and activities relating to the detection, assessment, understanding and prevention of adverse drug reactions or any other possible drug related problems and Risk Management Strategies which provides a structured and coherent approach to identifying, assessing and managing risk and builds in a process for regularly updating and reviewing the assessment based on new developments or actions taken, conference provides the foundation for strong strategic planning and practical decision-making in pharmacovigilance programs. Stakeholders from medicines research, global regulation, and healthcare will join together to analyse the challenges for safety and pharmacovigilance efforts in this uncertain environment and examine effective strategies for addressing gaps and needs.
Good laboratory practice for nonclinical studies
The GLP regulations have been enacted since 1978 and are currently under a proposed FDA amendment to revise terminology and accommodate other changes relating to advances in technology related to the industry. This book provides a unique opportunity to access interpretation of the 21CFR58 regulatory requirements from leading industry experts with a vast knowledge and expertise in their fields. The approach used takes the regulations, provides interpretations and references to examples and regulatory actions. Data integrity and the use of electronic systems in compliance with 21CFR11 Electronic Records: Electronic Signatures are also discussed.
Globalization and Health : Challenges for health law and bioethics
This timely collection explores ethical and legal dilemmas in healthcare arising from globalization. Conflicts between public interests and individual rights, the challenge of regulating professionals and access to health services, and the effects of a global market all feature prominently in contemporary debates in this area. As a result of globalization, issues in health law and bioethics can no longer be understood solely within political boundaries that define traditional notions of individuals and communities. Rather, solutions for emerging problems require a global conception of rights and obligations, including the re-evaluation of ethical frameworks and legal regimes that currently govern exchanges in healthcare. Leading scholars in bioethics, law, medicine and philosophy from various jurisdictions engage these themes in this volume, and demonstrate the need for transnational solutions in a global age of healthcare.
Global perspectives on recognising non-formal and Informal Learning : Why recognition matters
This book deals with the relevance of recognition and validation of non-formal and informal learning in education and training, the workplace and society. In an increasing number of countries, it is at the top of the policy and research agenda ranking among the possible ways to redress the glaring lack of relevant academic and vocational qualifications and to promote the development of competences and certification procedures which recognise different types of learning, including formal, non-formal and informal learning. The aim of the book is therefore to present and share experience, expertise and lessons in such a way that enables its effective and immediate use across the full spectrum of country contexts, whether in the developing or developed world. It examines the importance of meeting institutional and political requirements that give genuine value to the recognition of non-formal and informal learning; it shows why recognition is important and clarifies its usefulness and the role it serves in education, working life and voluntary work; it emphasises the importance of the coordination, interests, motivations, trust and acceptance by all stakeholders.
Global perspectives on health promotion effectiveness
This edited volume ... raises important questions about 'what counts as evidence and who gets to decide.' It presents important challenges to dominant biomedical approaches assessing evidence and effectiveness within health promotion ... offers an introduction to the key debates and challenges involved in the evaluation of health promotion programs, as well as some useful strategies for measuring their impact ... the authors acknowledge the value and legitimacy of a wide range of epistemological positions and scientific approaches and present their arguments using language and logic likely to be accessible and acceptable to researchers using different paradigms.
Global energy supply and emissions : An interdisciplinary view on effects, restrictions, requirements and options
offers an authoritative analysis of the state-of-the art in energy and climate research and policy. It starts by describing the current status of technologies that are expected to have an influence on the energy systems of the future. For an adequate evaluation, it presents the latest findings on the effects of energy supply and consumption as well as of the emissions on both the environment and people’s health. This is followed by an extensive discussion of the economic and social problems related to climate change, the need for energy transitions, and other issues that may require public investment and international agreements. reviews the problem of energy policy from a global perspective, providing readers with the technical, political, economic and ethical background needed to understand the current situation and work at better solutions for a sustainable, just and prospering world.
Geotechnics of Roads : Fundamentals
Presents stresses and strains in road structures, water and heat migration within and between layers of road materials, and the effects of water on the strength and stiffness of those materials. It includes a deep analysis of soil compaction, one of the most important issues in road construction. Compaction accounts for only a small proportion of a construction budget but its effects on the long-term performance of a road are decisive. In addition, the book describes methodologies for nondestructive road evaluation including analysis of continuous compaction control, a powerful technique for real-time quality control of road structures.
Geotechnics of Roads : Advanced Analysis and Modeling
Develops 23 extended examples that cover most of the theoretical aspects presented in the book Geotechnics of Roads: Fundamentals. Moreover, for most examples, Volume 2 describes algorithms for solving complex problems and provides Matlab® scripts for their solution.
Gender Equality Programmers in Higher Education : International Perspectives
For the last twenty years gender equality has been on the agenda of national higher education policies both within Europe and beyond it.the authors of this book analyse under which circumstances equality programmes are successful. In order to develop a deeper understanding of the mechanisms of and barriers to gender equality in higher education this book presents comparative studies and research focusing on the development of gender equality policies in different countries, as well as studies on the conditions for implementing policies, changes in strategies and the evaluation of gender equality programmes.
Gender Differences in Computer and Information Literacy : An In-depth Analysis of Data from ICILS
When computer technology was first introduced in schools, there was a prevailing belief that information and communication technologies were ‘boys’ toys’; boys were assumed to have more positive attitudes toward using computer technologies. As computer technologies have become more established throughout societies, gender gaps in students’ computer and information literacy appear to be closing, although studies into gender differences remain sparse.
Gastroesophageal reflux disease : Principles of disease, diagnosis, and treatment
Gastroesophageal reflux disease (GERD) is one of the most common disorders with an increasing prevalence and incidence in the last two decades. This book presents clinically relevant information for gastroenterologists, internists, surgeons, residents and also nurses, who frequently care for GERD patients.
Games and Simulations in Teacher Education
Includes more than twenty computer games and simulations for use in teacher training. Each of these simulations is innovative and presents an opportunity for pre-service teachers to have hands-on experience in an area of need prior to teaching in the classroom. Information on the simulation origins, including theoretical underpinnings, goals, characteristics, relevant research/program evaluation results, discussion of benefits and limitations as well as dissemination, recommended use, scope of practice, etc. of each game or simulation are included. Pre-service and new teachers will gain a number of useful skills through completion of these simulations and higher education faculty and administrators will gain a plethora of research-based and effective training tools for use in their teacher training programs.
Fundamentals of Powder Diffraction and Structural Characterization of Materials
Pecharsky (Iowa State University) and Zavalij (State University of New York, Binghamton) explain in their preface that the powder diffraction method has been used for more than 90 years as a means of structural characterization of materials; but it has become even more important to advancements in materials science, chemistry, physics, natural sciences, and engineering due to developments in the past decade such as digital x-ray recording, groundbreaking work showing the application of powder diffraction data to structure refinement and solution, and computers and the internet. This text for undergraduate and graduate students requires no prior knowledge of the subject. It provides both theoretical and practical coverage with emphasis on data collected using conventional x-ray sources and general-purpose powder diffractometers. The included CD-ROM contains color versions of some 300 illustrations as well as powder diffraction data needed for the end-of-chapter problems.
