الصفحة 8
الصفحة 8
IMPROVE - Innovative modelling approaches for production systems to raise validatable efficiency : Intelligent methods for the factory of the future
This open access work presents selected results from the European research and innovation project IMPROVE which yielded novel data-based solutions to enhance machine reliability and efficiency in the fields of simulation and optimization, condition monitoring, alarm management, and quality prediction.
Implementing semantic web services : The SESA framework
Service-oriented computing has become one of the predominant factors in IT research and development efforts over the last few years. In spite of several standardization efforts that advanced from research labs into industrial-strength technologies and tools, there is still much human effort required in the process of finding and executing Web services.
Immunogenicity of Biopharmaceuticals
This book is intended to give a broad overview of the current state-of-the-art regarding the immune response to biopharmaceuticals. The chapters range from an overview of the immune system and factors that may trigger the immune system, via detection of antibodies and clinical implications, to various case examples and the regulatory view on immunogenicity.
Immunogenetics of Autoimmune Disease
Utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion molecules, growth factors, antibodies, and other molecules induce and regulate critical cell functions that perpetuate inflammation, leading to tissue injury and clinical phenotype. The nature and intensity of this response as well as the physiological ability to restore homeostasis are to a large extent conditioned by the unique amino acid sequences that define allelic variants on each of the numerous participating mol ecules. Therefore, the coding genes in their germline configuration play a primary role in determining who is at risk for developing such disorders, how the disease progresses, and how someone responds to therapy. Although genetic components in these diseases are clearly present, the lack of obvious and homogeneous modes of transmission has slowed progress by prevent ing the full exploitation of classical genetic epidemiologic techniques. Furthermore, autoimmune diseases are characterized by modest disease risk heritability and m- tifaceted interactions with environmental influences. Yet, several recent discoveries have dramatically changed our ability to examine genetic variation as it relates to human disease. In addition to the development of large-scale laboratory methods and tools to efficiently recognize and catalog DNA diversity, over the past few years there has been real progress in the application of new analytical and data-manage ment approaches
Il solito Albert e la piccola Dolly : La scienza dei bambini e dei ragazzi = The usual Albert and little Dolly : The science of children and young people
After hundreds of years, science has come out of the ivory tower and entered society. Today science is not done with laboratory research alone but by involving different social actors. There are scientists, but also politicians, administrators, entrepreneurs and ordinary people, young and old. Their fears, real or perceived, can put a stop to its development. Their trust and their hopes nourish it and create a climate of expectations that are not always met. In the great narrative of science, the first actors, the scientists, are from time to time destroyers and benefactors, saints or monsters, fathers of the Golem with feet of clay or of Frankestein who turns and destroys. Not infrequently then there are many Sisyphus who continually restart their business - and it is not excluded that in the eyes of some they share with Penelope the habit of undoing at night what they do during the day.
Human-Computer Interaction and Cybersecurity Handbook - Human Factors and Ergonomics
Covers all areas of human–computer interaction and human factors in cybersecurity Includes information for IT specialists, who often desire more knowledge about the human side of cybersecurity Provides a reference for other disciplines such as psychology, behavioral science, software engineering, and security management Offers a source of information for cybersecurity practitioners in government agencies and private enterprises Presents new areas such as smart networking and devices
Human Rights and the Moral Responsibilities of Corporate and Public Sector Organisations
All students and advocates of human rights will be interested in this concerted exploration of the human rights moral obligations that fall, not directly on states, but on private and public organisations. Such an approach to human rights opens up the possibility of holding corporations and bureaucracies to account for human rights violations even when they have acted in accordance with the law. This interdisciplinary and international project brings together eminent philosophers, lawyers, social scientists and practitioners to articulate theoretically and develop in practical contexts the moral implications of human rights for non-state actors. What emerges from the book as a whole is a distinctive contemporary vision of the emerging moral impact of human rights and its significance for organisational behaviour and performance.
Human origins and environmental backgrounds
Human Origins and Environmental Backgrounds is a benchmark compendium of research that presents itself at a major paradigm shift in paleoanthropology. The editors offer a variety of theoretical approaches to puzzles on the place of the Hominidae, particularly Homo sapiens, among the Primates, including our unique bipedal positional behavior and social structure and the selective factors that might have been involved in our evolution in the broad context of Miocene and later environments. The contributors represent several generations of pioneering laboratory and field researchers from Japan, France and the United States, who have worked together over the past 40 years and who have trained future leaders in evolutionary anthropology and experimental primatology. This volume, compiled by the leading experts in the field, explores the interface between hominid origins and palaeoenvironments.
Human motion : Understanding, modeling, capture and animation
Edward Muybridge (1830–1904) is known as the pioneer in motion capt- ing with his famous experiments in 1887 called “Animal Locomotion”. Since then, the feld of animal or human motion analysis has grown in many dir- tions. However, research and results that involve human-like animation and the recovery of motion is still far from being satisfactory. Progress in human motion analysis depends on empirically anchored and grounded research in computer vision, computer graphics, and biomechanics. This book is based on a June 2006 workshop held in Dagstuhl, Germany. This workshop brought together for the frst time researchers from the afo- mentioned disciplines.
Human microbiome : Clinical implications and therapeutic interventions
The human microbiome refers to the complete microorganisms inhabiting the human body sites including skin, ear, nose, oral cavity, the genital, gastrointestinal and respiratory tracts, and body fluids such as breast milk, saliva, and urine. It is a significant and essential organ recognized for the body and has an established involvement in the host wellbeing, in terms of nutritional requirements and immunomodulation. Talks about how alteration and imbalance in the same can have clinical implications associated with a multitude of gastrointestinal, lifestyle-associated, and neurodegenerative disorders. How the proliferation of specific groups of bacteria and their metabolic activities, as a result of intestinal dysbiosis leads to the 'leaky gut' condition thereby influences brain activity via the bidirectional gut-brain axis. It also coves the importance of microbial seeding and how it can be influenced by the mode of delivery, nutrition, and medication. This book also provides various therapeutic interventions such as the establishment of stool banks and Faecal microbiota transplantation (FMT) that have recently proved promising in the treatment of ASD, Inflammatory Bowel Disease, and Ulcerative Colitis. This book provides a deeper understanding of the development of the human gut microbiome and the factors driving its dysbiosis. This book is a valuable read for health professionals, medical students, nutritionists, and scientific research communities who are eager to update themselves with recent trends in microbiome research. It will also aid gastroenterologists and nutritionists to make well-informed choices regarding therapeutic regimes.
Human Longevity, Individual Life Duration, and the Growth of the Oldest-Old Population
Old-age survival has considerably improved in the second half of the twentieth century. In this book, these fundamental questions are explored by experts from such diverse fields as biology, medicine, epidemiology, demography, sociology, and mathematics: they report on recent cutting-edge studies about essential issues of human longevity such as evolution of lifespan of species, genetics of human longevity, reasons for the recent improvement in survival of the elderly, medical and behavioral causes of deaths among very old people, and social factors of long survival in old age.
Human interface and the management of information : Interacting in information environments ; Symposium on Human Interface 2007, Held as Part of HCI International 2007, Beijing, China, July 22-27, 2007, Proceedings, Part II
The 12th International Conference on Human-Computer Interaction, HCI Inter- tional 2007, was held in Beijing, P.R. This volume, edited by Michael J. Smith and Gavriel Salvendy, contains papers in the thematic area of Human Interface and the Management of Information, addressing the following major topics: • Communication and Collaboration • Knowledge, Learning and Education • Mobile Interaction • Interacting with the World Wide Web and Electronic Services • Business Management and Industrial Applications • Environment, Transportation and Safety.
Human fungal diseases : Diagnostics, pathogenesis, drug resistance and therapeutics
Reviews the latest advancements in the fungal infections and their impact on human health. It presents epidemiology, diagnosis, pathogenesis, risk factors, virulence mechanisms, treatment, and strategies for the disease management and prevention of fungal infections. The book further reviews host-pathogen interactions, biofilm formation, and quorum sensing. It also covers the clinical manifestations, diagnostic approaches, and management strategies of opportunistic fungal infections, emerging fungal infections, and allergic fungal infections. It presents the latest advancements in diagnostic methods and therapeutic strategies, covering both conventional techniques and state-of-the-art approaches. Further, the book elucidates antifungal stewardship, nanotechnology, and omics technologies, providing insights into cutting-edge strategies for prevention, control, and management of multidrug-resistant fungi. This book is useful for researchers, students, and health professionals working in the fields of mycology, infectious diseases, immunology, dermatology, and pulmonology.
Human factors and voice interactive systems
Human Factors and Voice Interactive Systems, Second Edition provides in-depth information on current topics of major interest to speech application developers, and updates material from chapters that appeared in the previous edition.
Human Exploitation and Biodiversity Conservation
The sustainable use of biodiversity is one of the three key objectives of the 1992 "Convention on Biological Diversity". To achieve this, sound conservation practice has to be recognized as beneficial and implemented by all who access, or use it – from subsistence farmers to skiers and pharmaceutical bioprospectors. At the same time, indigenous peoples necessarily utilize enormous numbers of plants, fungi, and fish, particularly for foods and medicines. This book gathers together a wide range of contributions addressing diverse aspects of front-line human involvement in biodiversity exploitation and conservation. Its scope is broad, the organisms explored ranging from birds, invertebrates and mammals – both terrestrial and aquatic – to crops and medicinal plants. Meanwhile, the issues addressed include land use changes, the importance of gardens, hedges and green lanes, housing developments, hunting, invasive species, local community involvement, sacred groves, socioeconomic factors and trade.
Human and organisational factors : Practices and strategies for a changing world
This book addresses several questions regarding the implementation of human and organisational factors (HOF) so that recent improvements in industrial safety can be built upon.
Human and Animal Relationships
Pathogenic fungi are widely distributed and can infect many organisms, particularly humans, but also other vertebrates and insects. Due to a growing number of fungal infections, there is an increasing need to understand the interaction of pathogenic fungi with their hosts. This second completely updated and revised edition of Volume VI of The Mycota consists of state of the art reviews written by experts in the field, covering three major areas of this rapidly developing field. In the first part the current understanding of pathogenic fungi and the physiological reactions relevant for the pathogen - host interaction are elucidated. The second part describes novel technologies for the identification of proteins, virulence factors and mechanisms central to the host - pathogen interaction. The third part deals with the characterization of the host response towards pathogenic fungi and addresses timely clinical aspects.
Housing Market Dynamics in Africa
Utilizes new data to thoroughly analyze the main factors currently shaping the African housing market. Some of these factors include the supply and demand for housing finance, land tenure security issues, construction cost conundrum, infrastructure provision, and low-cost housing alternatives. Through detailed analysis, the authors investigate the political economy surrounding the continent’s housing market and the constraints that behind-the-scenes policy makers need to address in their attempts to provide affordable housing for the majority in need. With Africa’s urban population growing rapidly, this study highlights how broad demographic shifts and rapid urbanization are placing enormous pressure on the limited infrastructure in many cities and stretching the economic and social fabric of municipalities to their breaking point. But beyond providing a snapshot of the present conditions of the African housing market, the book offers recommendations and actionable measures for policy makers and other stakeholders on how best to provide affordable housing and alleviate Africa’s housing deficit.
Host-pathogen interactions : Methods and protocols
Serves as multidisciplinary compendium of approaches and techniques employed to analyze the role of different molecules, processes, or strategies used by different guests to survive and proliferate in their associations with eukaryotic hosts. Beginning with animal-pathogen interactions, the book then continues with chapters exploring virus-host interactions, plant-microbe interactions, as well as different molecular techniques that were initially applied to non-pathogenic interactions but can be adapted to study other host-pathogen associations. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips for troubleshooting and avoiding known pitfalls.
Hospitality marketing and consumer behavior : Creating memorable experiences
Drawing on global experiences, this new book, Hospitality marketing and consumer behavior: Creating memorable experiences, looks at the diverse factors that create these positive experiences and provides insight into marketing and consumer behavior in the context of hospitality and tourism. The dynamics of emerging economies has been captured, and some lessons have been drawn from best practices across the globe. The book covers marketing research, different elements of the marketing mix, consumer feedback and recovery, technology, people aspects, and how they impact consumer experience.
