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Actin-Binding Proteins and Disease
This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin ¾4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.
Across the Sahara : Tracks, trade and cross-cultural exchange in Libya
Provides a multi-perspective approach to the caravan trade in the Sahara during the 19th century. Based on travelogues from European travelers, recently found Arab sources, historical maps and results from several expeditions, the book gives an overview of the historical periods of the caravan trade as well as detailed information about the infrastructure which was necessary to establish those trade networks.
Acoustics of Wood
From the reviews of the 1st edition: "It will surely remain the most comprehensive work in this field for a long time to come. It belongs on the bookshelf of every material scientist and structural engineer."
Acoustic sensing techniques for the shallow water environment : Inversion methods and experiments
Contains the collection of papers from the second workshop on Experimental Acoustic Inversion Techniques for Exploration of the Shallow Water Environment. Acoustic techniques provide the most effective means for remote sensing of ocean and sea floor processes, and for probing the structure beneath the sea floor. No other energy propagates as efficiently in the ocean: radio waves and visible light are severely limited in range because the ocean is a highly conductive medium. However, sound from breaking waves and coastal shipping can be heard throughout the ocean, and marine mammals communicate acoustically over basin scale distances.
Achieving the Paris climate agreement goals : Global and regional 100% renewable energy scenarios with non-energy GHG Pathways for +1.5°C and +2°C
Presents detailed pathways to achieve 100% renewable energy by 2050, globally and across ten geographical regions. Based on state-of-the-art scenario modelling, it provides the vital missing link between renewable energy targets and the measures needed to achieve them. Bringing together the latest research in climate science, renewable energy technology, employment and resource impacts, the book breaks new ground by covering all the elements essential to achieving the ambitious climate mitigation targets set out in the Paris Climate Agreement. For example, sectoral implementation pathways, with special emphasis on differences between developed and developing countries and regional conditions, provide tools to implement the scenarios globally and domestically. Non-energy greenhouse gas mitigation scenarios define a sustainable pathway for land-use change and the agricultural sector. Furthermore, results of the impact of the scenarios on employment and mineral and resource requirements provide vital insight on economic and resource management implications.
Accounting, Cash Flow and Value Relevance
Investigates the value relevance of the operating cash flow as reported under the International Financial Reporting Standards (IAS/IFRS) for the largest European listed companies and US listed companies in the past recent years. Using the model based on the valuation theory developed by Ohlson, which measures the market value of equity as a function of accounting variables, the author concludes that operating cash flow represents a significant variable in determining the value relevance of the largest European and US listed companies. These findings provide siginificant implications for standard setters and support the continued requirements for disclosure of cash flow information under IAS 7.
Accelerator-Driven System at Kyoto University Critical Assembly
This book is a unique compilation of experimental benchmark analyses of the accelerator-driven system (ADS) at the Kyoto University Critical Assembly (KUCA) on the most recent advances in the development of computational methods.
Academic Scientists at Work
This book focuses on the three aspects of promotion in an academic setting: Scholarship, Teaching, and Service. Templates and worksheets designed to help you navigate your career with point-by-point instructions on how to complete them are provided. In addition to updating the contents of the previous version, this second edition includes a dozen articles written by the authors on managing your career that first appeared in Science's Next Wave.
Academic Integrity in Canada : An Enduring and Essential Challenge
Firmly grounded in the scholarly literature globally, it engages with the experience of local practicioners. It presents aspects of academic integrity that is specific to Canada, such as the existence of an "honour culture", rather than relying on an "honour code". It also includes Indigenous voices and perspectives that challenge traditional understandings of intellectual property, as well as new understandings that have arisen as a consequence of Covid-19 and the significant shift to online and remote learning.
Abstraction, Reformulation, and Approximation ; 7th International Symposium, SARA 2007, Whistler, Canada, July 18-21, 2007, Proceedings
This volume contains the proceedings of SARA 2007, the seventh symposium, held at Whistler Village, British Columbia, Canada, July 18-21. Three distinguished speakers were invited to give keynote presentations, and their abstracts are included herein,It has been recognized since the inception of artificial intelligence that abstractions, problem reformulations and approximations (AR&A) are central to human common-sense reasoning and problem solving and to the ability of systems to reason effectively in complex domains.AR&A techniques have been used in a variety of problem-solving settings, including automated reasoning, cognitive modelling.
Abstraction, reformulation and approximation ; 6th International symposium, SARA 2005, Airth Castle, Scotland, UK, July 26-29, 2005, proceedings
This volume contains the proceedings of the 6th Symposium on Abstraction, Reformulation and Approximation (SARA 2005). the proceedings have been published in the LNAI series of Springer. Abstractions, reformulations and approximations (AR&A) have found app- cationsin avarietyofdisciplines andproblems, including constraintsatisfaction, design, diagnosis, machine learning, planning, qualitative reasoning, scheduling, resource allocation and theorem proving, but are also deeply rooted in philo- phy and cognitive science. The papers in this volume capture a cross-section of the various facets of the ?eld and of its applications. One of the primary uses of AR&A is oriented to overcome computational intractability. AR&A techniques, however, have also proved useful for knowledge acquisition, explanation and other applications.
Abstraction, refinement and proof for probabilistic systems
Probabilistic techniques are increasingly being employed in computer programs and systems because they can increase efficiency in sequential algorithms, enable otherwise nonfunctional distribution applications, and allow quantification of risk and safety in general. This makes operational models of how they work, and logics for reasoning about them, extremely important. Abstraction, Refinement and Proof for Probabilistic Systems presents a rigorous approach to modeling and reasoning about computer systems that incorporate probability. Its foundations lie in traditional Boolean sequential-program logic—but its extension to numeric rather than merely true-or-false judgments takes it much further, into areas such as randomized algorithms, fault tolerance, and, in distributed systems, almost-certain symmetry breaking. The presentation begins with the familiar "assertional" style of program development and continues with increasing specialization: Part I treats probabilistic program logic, including many examples and case studies; Part II sets out the detailed semantics; and Part III applies the approach to advanced material on temporal calculi and two-player games.
Abord clinique des urgences traumatiques au cabinet du généraliste = Clinical approach to traumatic emergencies in the general practitioner's office
Cet ouvrage a été conçu comme une aide pour le médecin généraliste, confronté quotidiennement à la pathologie traumatique. Les deux auteurs, urgentistes expérimentés, apportent des réponses claires, concises et pratiques aux problèmes que posent les lésions traumatiques. Des gestes simples, un abord clinique détaillé, la nécessité de recourir ou non à des examens complémentaires ou à un avis spécialisé sont ici expliqués et justifiés. Le style est précis, concis, et un lexique complète les définitions et les matériels cités dans le texte. Les auteurs se sont entourés des avis de généralistes et de spécialistes pour définir des conduites à tenir simples et compatibles avec les nécessités du terrain.
A Theory of Marketing : Outline of a Social Systems Perspective
Marketing has become one of the most influential forces in contemporary market economies. Yet despite ubiquitous empirical presence, uncountable textbook definitions, and sixty years of scholarly work, a coherent sociological understanding of this powerful concept is still amiss. Drawing on Luhmannian social systems theory, historical analysis, and four qualitative studies, the author theorizes on the marketing function as a self-contained system of communications. It is argued that marketing systems prosper within a host organization if and as long as they successfully influence observers' preferences towards particular brands. On these conceptual foundations a comprehensive brand- and communication-centered theory is developed that fulfills Alderson', Cox' and Bartels' foundational requirements for a general theory of marketing in an unprecedented way.
A Short Course on Operator Semigroups
Gives a streamlined and systematic introduction to strongly continuous semigroups of bounded linear operators on Banach spaces. It treats the fundamental Hille-Yosida generation theorem as well as perturbation and approximation theorems for generators and semigroups.
A Rosicrucian Utopia in Eighteenth-Century Russia : The Masonic Circle of N.I. Novikov
The author undertakes an investigation into the history of Russian Freemasonry that has not been attempted previously. Her premise is that the Russian Enlightenment shows peculiar features, which prevent the application of the interpretative framework commonly used for the history of western thought. The author deals with the development of early Russian masonry, the formation of the Novikov circle in Moscow, the ‘programme’ of Rosicrucianism and the character of its Russian variant and, finally, the clash between the Rosicrucians and the State. The author concludes that the defenders of the Ancien Régime were not wrong. In fact the democratic behaviour, the critical attitude, the practice of participation, the freedom of thought, the tolerance for the diversity, the search for a direct communication with the divinity.
A rose armed with thorns : Spinoza’s Philosophy under a novel lens
Presents a systemic analysis of Spinoza’s philosophy and challenges the traditional views. It deals with Spinoza’s concepts of substance, truth conditions, attributes, and the first, second, and supreme grades of knowledge. Based upon an analysis of the relevant details in all of Spinoza’s philosophical works, reveals many important points, including the following: Spinoza’s system is not, nor is meant to be, a foundational-deductive system but was meant to be a coherent system of a network model. Spinoza’s reality is not made in the image of a mathematical model. Imaginatio, the first grade of knowledge, and ratio, the second grade, are parts or properties of the supreme grade of knowledge, scientia intuitiva, which is their essence.
A Remarkable Collection of Babylonian Mathematical Texts : Manuscripts in the Schøyen Collection: Cuneiform Texts I
This new text from Jöran Friberg, the leading expert on Babylonian mathematics, presents 130 previously unpublished mathematical clay tablets from the Norwegian Schøyen collection, and provides a synthesis of the author's most important work. Through a close study of these tablets, Friberg has made numerous amazing discoveries, including the first known examples of pre-Classical labyrinths and mazes, a new understanding of the famous table text Plimpton 322, and new evidence of Babylonian familiarity with sophisticated mathematical ideas and objects, such as the three-dimensional Pythagorean equation and the icosahedron.
A Practical Theory of Reactive Systems : Incremental Modeling of Dynamic Behaviors
Presents a ""practical theory"" of reactive systems, with formal foundations in Temporal Logic of Actions. This book emphasises theoretical understanding of reactive behaviors and using ""horizontal"" modularity to manage their complexity. It illustrates the incremental specification by a number of examples of varying size and complexity
A practical guide to corporate finance : Breaking the financial lce
Offers an approachable guide to all key concepts within corporate finance. Emphasizing the use of common sense rather than number-crunching models, A practical guide to corporate finance begins with the basics of how to read financial statements and how to estimate future cash flows. It also includes a guide to subjects such as capital budgeting decisions, the cost of financing for businesses, cash and working capital management, The process of business valuation, and how stock markets work. This textbook breaks the financial ice by offering real, practical advice, helping the reader to avoid common pitfalls, and translate the 'financialese', or business jargon that can cause confusion for those without a financial or banking background.
