Bioequivalence of topical generic products
Bioequivalence (BE) assessment of topical dermatological products is a long standing challenge. The development of generic topical dermatological products has often been hampered due to the limited number of acceptable approaches, which are capable of determining the BE between generic products and reference list products. Currently, except in the case of dermatological corticosteroids, the golden rule to establish the BE of most topical dermatological products still heavily relied on clinical endpoint trials, which are often unreliable, time-consuming and expensive. The regulatory agencies and pharmaceutical industries are forging ahead to the development of new surrogate BE assessment approaches for other topical dermatological products. These promising approaches include dermatopharmacokinetic study (DPK), dermal microdialysis (DMD), near-infrared spectrometry (NIR), and confocal Raman spectroscopy (CRS).
Biodiversity and Ecophysiology of Yeasts
In the last few decades more and more yeast habitats that were not investigated earlier, spanning cold climates to tropical regions and dry deserts to rainforests, have been explored. As a result, a large body of ecological data has been accumulated and the number of known yeast species has increased rapidly. This book provides an overview of the biodiversity of yeasts in different habitats. The recent advances achieved by the application of molecular biological methods in the field of yeast taxonomy and ecology are also incorporated in the book. Wherever possible, the interaction between yeasts and the surrounding environment is discussed.
Bioceramics and alternative bearings in joint arthroplasty ; 10th BIOLOX Symposium. Washington D.C., June 10-11, 2005. Proceedings
This group accomplishment has been made possible by the superb cooperation received from the speakers in sending us their manuscripts on a timely basis as well as by the supporting staff at both CeramTec and at the Publishing House in executing all of the details needed. We specially extend our most heartfelt thanks to the Scientific Committee for their assistance in evaluating and selecting the submissions as well as developing the Symposium program. We are more convinced than ever that the proceedings of this Symposium are a continuation of CeramTec's tradition of providing all members of the orthopedic surgical community with a valuable addition to your reference libraries. We hope that this book will present you with the latest and most up to date source of scientific and clinical information regarding the use of ceramics and other alternative bearings in joint replacement surgery.
Bioactive Marine Natural Products
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R&D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.
Big little hotel : Small hotels designed by architects
This book showcases small hotels, all located in the United States, designed by architects who use light and materials in interesting and intentional ways. The designs also deliberately connect to their local history, context, or land – in many cases all three. Both the architecture and the operations harmonize with the place, whether that is a bustling city, small town, or natural area. Many are new buildings but some are adaptive reuse projects or renovations of historic properties, extending the connectivity of the place into the future.
Big Data Recommender Systems ; Vol.2 : Application Paradigms
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools. First designed to generate personalized recommendations to users in the 90s, recommender systems apply knowledge discovery techniques to users’ data to suggest information, products, and services that best match their preferences. In recent decades, we have seen an exponential increase in the volumes of data, which has introduced many new challenges. recommender systems. Volume 2 covers a broad range of application paradigms for recommender systems over 22 chapters
Big Data and Global Trade Law
Explores the relevance of global trade law for data, big data and cross-border data flows. Contributing authors from different disciplines including law, economics and political science analyze developments at the World Trade Organization and in preferential trade venues by asking what future-oriented models for data governance are available and viable in the area of trade law and policy. The collection paints the broad picture of the interaction between digital technologies and trade regulation as well as provides in-depth analyses of critical to the data-driven economy issues, such as privacy and AI, and different countries' perspectives.
Best practices in endodontics : A desk reference
A compilation of practical information shared by some of the finest clinical endodontists in the world. Most of the chapters focus on how to perform a single clinical procedure. Written in simple language with ample photographic support. Provides guidance for most common endodontic procedures but also for some procedures that are less common, such as how to treat teeth containing Russian Red; surgical extrusion; root submergence; and decompression. Because most of the procedures described are performed under a dental operating microscope, there are chapters on operatory design for microscopic endodontics, microscope ergonomics for the doctor and assistant, and how to set up and use a microscope for photography and video documentation.
Benign anorectal diseases : Diagnosis with endoanal and endorectal ultrasound and new treatment options
New three-dimensional endoanal and endorectal ultrasonographic and magnetic resonance imaging techniques have given better insight into the complex anatomy of the pelvic floor and its pathologic modification in benign anorectal diseases. Obstetrical events leading to fecal incontinence in females, the relationship between fistulous tracks and the sphincter complex, and mechanisms of obstructed defecation syndrome can now be accurately evaluated, which is of fundamental importance for decision making.
Beginning Python : From novice to professional
Gain a fundamental understanding of Python's syntax and features with the second edition of Beginning Python, an up–to–date introduction and practical reference. Covering a wide array of Python–related programming topics, including addressing language internals, database integration, network programming, and web services, you'll be guided by sound development principles. Ten accompanying projects will ensure you can get your hands dirty in no time. Updated to reflect the latest in Python programming paradigms and several of the most crucial features found in Python 3.0 (otherwise known as Python 3000), advanced topics, such as extending Python and packaging/distributing Python applications, are also covered
Beginning HTML with CSS and XHTML : Modern Guide and Reference
Beginning HTML with CSS and XHTML: Modern Guide and Reference incorporates practical examples that will show you how to structure your data correctly using (X)HTML, along with styling and layout basics using Cascading Style Sheets (CSS). Youll also learn how to add dynamic behavior to your data using the JavaScript™ language.
Beginning Google Maps Applications with PHP and Ajax : From novice to professional
Until recently, building interactive web-based mapping applications has been a cumbersome affair. This changed when Google released its powerful Maps API. Beginning Google Maps Applications with PHP and Ajax was written to help you take advantage of this technology in your own endeavorswhether you're an enthusiast playing for fun or a professional building for profit. This book covers version 2 of the API, including Google's new Geocoding service. As well as providing hands-on examples of real mapping projects, this book supplies a complete reference for the Maps API, along with the relevant aspects of JavaScript, CSS, PHP, and SQL. Visit the authors' website for additional tips and advice.
Beginning CSS web development : From novice to professional
There are many books out there on CSS, but Beginning CSS Web Development is different—it doesn't waste time discussing theory, and it delves straight into the practical matter. It provides you with what you need to know, faster. It is also completely up to date, covering the most modern CSS standards and design techniques. In addition to the essential CSS basics, this book covers advanced techniques like accessibility, hacks, and filters. The book concludes with a case study, and features a CSS reference section that allows you to look up required syntax as quickly as possible.
Bayesian core : A practical approach to computational Bayesian statistics
This Bayesian modeling book provides an operational methodology for conducting Bayesian inference, rather than focusing on its theoretical justifications. Special attention is paid to the derivation of prior distributions in each case and specific reference solutions are given for each of the models.
Basics of PET Imaging : Physics, Chemistry, and Regulations
This unparalleled text on the basics of PET imaging technology is an ideal resource for technologists and residents preparing for board examinations. the book also serves as a useful reference for practicing nuclear medicine professionals. Chapters are concise but comprehensive and emphasize the fundamentals, including physics, instrumentation and data acquisition, image reconstruction, production of PET radionuclides and radiopharmaceuticals, and regulatory and reimbursement issues.
Basics of dental technology : a step by step approach
A complete reference for the current techniques and materials used in dental technology. Retains the accessible, task-based approach and step-by-step guidance. Features digital dental technology and an interactive student website to support self-assessment. Explains key competencies, concepts, instruments, and equipment, and also introduces more specialist techniques and procedures, such as denture prosthetics, fixed prosthodontics and orthodontic work. Provides essential information for trainee dental technicians and students learning about dental technology, including study tips and strategies for working effectively within a dental team
BASICS fundamentals of presentation : Detail drawing
Detailed drawings are developed on the basis of the working drawings; they form an important part of the specification and contain precise information for the tradesmen, indicating how materials are to be used and how they are to be joined. Drawings are produced in various degrees of detail. Depending on the function of the drawings, they are produced in scales from 1:20 to 1:1 in order to define the materials and method of joining, and to better illustrate the various dimensions. Basics Detailed Drawings explains, step by step, how to compose detailed designs and produce correct construction drawings, using clear examples
Basics fire safety
It consists of measures to prevent fires from starting, to facilitate the rescue of individuals in a burning building, and to help firefighters contain a blaze. The book explains the general concepts and fundamental issues of fire safety in building design beyond the particulars of local building regulations
Basic theoretical physics : A concise overview
This concise treatment embraces, in four parts, all the main aspects of theoretical physics (I . Mechanics and Basic Relativity, II. Electrodynamics and Aspects of Optics, III. Non-relativistic Quantum Mechanics, IV. Thermodynamics and Statistical Physics). It summarizes the material that every graduate student, physicist working in industry, or physics teacher should master during his or her degree course. It thus serves both as an excellent revision and preparation tool, and as a convenient reference source, covering the whole of theoretical physics. It may also be successfully employed to deepen its readers' insight and add new dimensions to their understanding of these fundamental concepts. Recent topics such as holography and quantum cryptography are included, thus making this a unique contribution to the learning material for theoretical physics.
Basic Probability Theory with Applications
This book presents elementary probability theory with interesting and well-chosen applications that illustrate the theory. An introductory chapter reviews the basic elements of differential calculus which are used in the material to follow. The theory is presented systematically, beginning with the main results in elementary probability theory. This is followed by material on random variables. Random vectors, including the all important central limit theorem, are treated next. The last three chapters concentrate on applications of this theory in the areas of reliability theory, basic queuing models, and time series. Examples are elegantly woven into the text and over 400 exercises reinforce the material and provide students with ample practice.



















