Artificial intelligence in drug design
Looks at applications of artificial intelligence (AI), machine learning (ML), and deep learning (DL) in drug design. The chapters in this book describe how AI/ML/DL approaches can be applied to accelerate and revolutionize traditional drug design approaches such as: structure- and ligand-based, augmented and multi-objective de novo drug design, SAR and big data analysis, prediction of binding/activity, ADMET, pharmacokinetics and drug-target residence time, precision medicine and selection of favorable chemical synthetic routes. How broadly are these approaches applied and where do they maximally impact productivity today and potentially in the near future.
Artificial intelligence for multisource geospatial information
Collects 10 original research contributions published in the Special Issue entitled “Artificial Intelligence for Multisource Geospatial Information” of the ISPRS International Journal of Geo-Information. The focus is on different methods of Geospatial Artificial Intelligence (GeoAI) based on deep learning using different network architectures, clustering, soft computing, and semantic approaches. They are proposed to deal with a variety of Geospatial Big Data (GBD), such as georeferenced texts and photos in social networks, remote sensing images, cartographic maps, multidimensional geo databases, metadata in spatial data infrastructures, and for different tasks, such as for multisource georeferenced text integration and geodata flexible querying, for social sensing by applying sentiment analysis, clustering and geo analysis, for segmentation of roads, clouds and snow, and for detection of small targets and people on the streets.
Artificial intelligence and machine learning techniques for civil engineering
Offers state-of-the-art contributions in the area of AI and its applications in the field of civil engineering presenting methods and implementation of AI and machine learning in multiple facets of civil engineering
Artificial Intelligence and International Economic Law : Disruption, Regulation, and Reconfiguration
This book was finalized while countries around the world were still confronting a global public health crisis caused by the COVID-19 pandemic. Many came to rely on digital services as an infrastructure for social interaction and professional endeavors, including academic and educational work. The pandemic seems to have precipitated a further shift towards digital technologies and artificial intelligence. It is our hope that this book will contribute to an informed discussion about the relevance of and implications for international economic law beyond the pandemic"
Arithmetical investigations : Representation theory, orthogonal polynomials, and quantum interpolations
In this volume the author further develops his philosophy of quantum interpolation between the real numbers and the p-adic numbers. The p-adic numbers contain the p-adic integers Zp which are the inverse limit of the finite rings Z/pn. This gives rise to a tree, and probability measures w on Zp correspond to Markov chains on this tree. From the tree structure one obtains special basis for the Hilbert space L2(Zp,w). The real analogue of the p-adic integers is the interval [-1,1], and a probability measure w on it gives rise to a special basis for L2([-1,1],w) - the orthogonal polynomials, and to a Markov chain on "finite approximations" of [-1,1]. For special (gamma and beta) measures there is a "quantum" or "q-analogue" Markov chain, and a special basis, that within certain limits yield the real and the p-adic theories. This idea can be generalized variously. In representation theory, it is the quantum general linear group GLn(q)that interpolates between the p-adic group GLn(Zp), and between its real (and complex) analogue -the orthogonal On (and unitary Un )groups. There is a similar quantum interpolation between the real and p-adic Fourier transform and between the real and p-adic (local unramified part of) Tate thesis, and Weil explicit sums.
Arithmetic of finite fields ; 1st International Workshop, WAIFI 2007, Madrid, Spain, June 21-22, 2007, Proceedings
This book presented structures in finite fields, efficient implementation and architectures, efficient finite field arithmetic, classification and construction of mappings over finite fields, curve algebra, cryptography, codes, and discrete structures.
Arctic Alpine ecosystems and people in a changing environment
This book addresses the significant environmental changes experienced by high latitude and high altitude ecosystems at the beginning of the 21st c- tury. Increased temperatures and precipitation, reduction in sea ice and glacier ice, the increased levels of UV-radiation and the long-range tra- ported contaminants in arctic and alpine regions are stress factors that challenge terrestrial and aquatic ecosystems. The large natural variation in the physical parameters of these extreme environments is a key factor in structuring the biodiversity and biotic productivity, and the effect of the new stress factors can be critical for the population structures and the - teraction between species. These changes may also have socio-economic effects if the changes affect the bio-production, which form the basis for the marine and terrestrial food chains. The book is uniquely multidisciplinary and provides examples of va- ous aspects of contemporary environmental change in arctic and alpine - gions. The 21 chapters of the book are organised under the fields of •Climate change and ecosystem response, •Long range transport of poll- ants and ecological impacts, and •UV radiation and biological effects, each also including aspects of the •Socio-economic effects of environmental change. The introductory chapter presents and explains the internal c- nection and integration of all chapters.
Architecture in context : Designing in the Middle East
Provides a foundation for understanding the critical context of architecture and design in this region. It does this by: presenting a practical overview of architectural know-how in the Middle East, and its potential for cultivating a sense of place introducing local architectural vocabularies and styles, and how they can still be reactivated in contemporary design exploring the cultural and contextual meaning of forms as references that may influence contemporary architecture discussing important discourses and trends in architecture that allow a rethinking of the current global/local dichotomy.
Architecture description languages ; IFIP TC-2 workshop on architecture description languages (WADL), World Computer Congress, Aug. 22-27, 2004, Toulouse, France
These proceedings record the papers presented at the Workshop onArchitecture Description Languages held in the city of Toulouse in thesouth of France.The aim of an ADL (Architecture Description Language) is to formallydescribe software and hardware architectures. Usually, an ADL describescomponents, their interfaces, their structures, their interactions (structureof data flow and control flow) and the mappings to hardware systems. Amajor goal of such descriptions is to allow analysis with respect to severalaspects like timing, safety, reliability, ...
Architecture and design for industry 4.0 : Theory and practice
The book is structured into three sections (research, practice, and technologies), with the goal of creating a new framework useful for widespread awareness necessary to initiate technology transfer processes for the benefit of the public sector, universities, research centers, and innovative companies, and a new professional figure capable of controlling the entire process is essential. Thus, the book chapters arouse a series of relevant topics such as computational and parametric design, performance-based architecture, data-driven design strategies, parametric environmental design and analysis, computational and parametric structural design and analysis
Architectural tiles : Conservation and restoration
It not only contains new and up to date information on materials, practical methods, and historical research but also reflects changes in the attitudes, outlook and perceptions within the wider conservation, architectural heritage and construction communities which give a new dimension to the conservation and restoration. The growing interest in the preservation of post war ceramic tile murals and the subsequent demand for information pertaining specifically to this era is a welcome and useful addition.
Architectural Terra Cotta : Design concepts, techniques and applications
Examines the evolution of terra cotta and prepares architects and builders to make new, creative uses of the timeless material. Terra cotta is among the oldest of manufactured building products, yet it has once again become a material of choice in contemporary façade design. From the walls of Babylon to high performance rainscreens, terra cotta claddings have repeatedly proven to be technically superior and aesthetically triumphant. Understanding the evolution of terra cotta prepares architects to add new, creative chapters to a rich history.
Architectural structures : Visualizing load flow geometrically
Presents an alternative approach to understanding structural engineering load flow using a visually engaging and three-dimensional format. This book presents a ground-breaking new way of establishing equilibrium in architectural structures using the Modern Müller-Breslau method. Includes approachable coverage of parametric modeling of two-dimensional and three-dimensional structures, as well as more advanced topics such as indeterminate structural analysis and plastic analysis. Hundreds of detailed drawings created by the author are included throughout to aid understanding. Architecture and structural engineering students can employ this novel method by hand sketching, or by programming in parametric design software.
Architectural graphics ; 6th ed.
Offers a comprehensive introduction to using graphic tools and drafting conventions to translate architectural ideas into effective visual presentations, using hundreds of the author's distinctive drawings to illustrate the topic effectively. Includes new information on orthographic projection in relation to 3D models, and revised explanations of line weights, scale and dimensioning, and perspective drawing to clarify some of the most difficult concepts. New examples of modern furniture, APA facilities, and presentation layout provide more up-to-date visuals, and the Reference Center features all new animations, videos, and practice exercises. Architectural graphics are key tools for conveying design through representation on paper or on screen, and this book is the ultimate guide to mastering the skill, then applying your talent to create more effective design communication.
Architectonics and parametric thinking : computational modeling for beginning design
Architectonics and Parametric Thinking begins by clearly positioning the potentials of parametric design through a series of chapters written by leaders in their respective industries. This helps to situate the vast potential of parametric softwares, allowing the reader to understand the full range of what is made possible by working computationally. Following this theoretical introduction, the book presents a manual that walks readers through the step-by-step construction of parametric modeling scripts built through an architectonic lens using clear, compelling diagrams.
Architecting dependable systems V
As software systems become increasingly ubiquitous, the issues of dependability become more and more crucial. Given that solutions to these issues must be considered from the very beginning of the design process, it is reasonable that dependability is addressed at the architectural level. This book was born of an effort to bring together the research communities of software architectures and dependability.
Arch bridges : Proceedings of the first international conference on arch bridges held at Bolton, UK on 3–6 September 1995
In the twentieth century bridge engineers have seen many changes. Advances in technology, materials and engineers understanding of structural behaviour and methods of analysis has presented opportunities for innovation and have led to increasingly sophisticated solutions to the basic problem of providing a bridge over an obstacle. However, despite these innovative technological changes, the masonry arch bridge has shown itself to be a durable, cost-effective structure, tolerant of its modern environment and out-performing many of its competitors.
Aquaculture Perspective of Multi-Use Sites in the Open Ocean : The Untapped Potential for Marine Resources in the Anthropocene
This volume addresses the potential for combining large-scale marine aquaculture of macroalgae, molluscs, crustaceans, and finfish, with offshore structures, primarily those associated with energy production, such as wind turbines and oil-drilling platforms. The volume offers a comprehensive overview and includes chapters on policy, science, engineering, and economic aspects to make this concept a reality. The compilation of chapters authored by internationally recognized researchers across the globe addresses the theoretical and practical aspects of multi-use, and presents case studies of research, development, and demonstration-scale installations in the US and EU
Approximation and Online Algorithms ; Vol.3879 : 3rd International Workshop, WAOA 2005, Palma de Mallorca, Spain, October 6-7, 2005, Revised Selected Papers
The third Workshop on Approximation and Online Algorithms (WAOA 2005) focused on the design and analysis of algorithms for online and computationally hard problems. Both kinds of problems have a large number of applications from a variety of ?elds. WAOA 2005 took place in Palma de Mallorca, Spain, on 6–7 October 2005. The workshop was part of the ALGO 2005 event that also hosted ESA, WABI, and ATMOS. The two previous WAOA workshops were held in Budapest (2003) and Rome (2004).
Approximation and Online Algorithms ; 5th International Workshop, WAOA 2007, Eilat, Israel, October 11-12, 2007. Revised Papers
The Fifth Workshop on Approximation and Online Algorithms (WAOA 2007) focused on the design and analysis of algorithms for online and computationally hard problems.



















