Analyzing computer system performance with Perl::PDQ
Analyzing computer system performance is often regarded by most system administrators, IT professionals and software engineers as a black art that is too time consuming to learn and apply. Finally, this book by acclaimed performance analyst Dr. Neil Gunther makes this subject understandable and applicable through programmatic examples. The means to this end is the open-source performance analyzer Pretty Damn Quick (PDQ) written in Perl As the epigraph in this book points out, Common sense is the pitfall of performance analysis. The performance analysis framework that replaces common sense is revealed in the first few chapters of Part I. The important queueing concepts embedded in PDQ are explained in a very simple style that does not require any knowledge of formal probability theory. Part II begins with a full specification of how to set up and use PDQ replete with examples written in Perl. Subsequent chapters present applications of PDQ to the performance analysis of multicomputer architectures, benchmark results, client/server scalability, and Web-based applications.
Analytics of Protein-DNA Interactions
This book covers trends in modern biotechnology. All aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science, are treated. More information as well as the electronic version is available at springer.com.
Analytical scientists in pharmaceutical product development : Task management and practical knowledge
Explains task management concepts and outlines practical knowledge to help pharmaceutical analytical scientists become productive and enhance their career. •Presents broad topics such as product development process, regulatory requirement, task and project management, innovation mindset, molecular recognition, separation science, degradation chemistry, and statistics. •Provokes thinking through figures, tables, and case studies to help understand how the various functions integrate and how analytical development can work efficiently and effectively by applying science and creativity in their work. •Discusses how to efficiently develop a fit-for-purpose HPLC method without screening dozens of columns, gradients, or mobile phase combinations each time, since the extra effort may not provide enough of a benefit to justify the cost and time in a fast-paced product development environment.
Analyse asymptotique et couche limite = Asymptotic analysis and boundary layer
The aim of the book is to give teachers and students (from Bac + 4) in applied mathematics and fluid mechanics a teaching and learning tool illustrated by fifty problems accompanied by their detailed correction. This book presents a new method of asymptotic analysis for "boundary layer" problems. This is called MASC "Method of Complementary Successive Approximations". The first half of the book is devoted, in addition to the presentation of the MASC, to organize the knowledge necessary for the asymptotic analysis and to give the keys allowing the understanding of what is a problem called "boundary layer" and the methods allowing. to build an approximation. The second part is devoted to the application of MASC in fluid mechanics and to the comparison with the more traditional methods resulting from the famous MDAR, "Method of Connected Asymptotic Developments".
Analog Design Centering and Sizing
This book represents a compendium of fundamental problem formulations of analog design centering and sizing. It provides a differentiated knowledge about the tasks of analog design centering and sizing. In particular the worst-case problem will be formulated. It stands at the interface between process technology and design technology.Analog Design Centering and Sizing wants to point out that and how both process and design technology are required for its solution. The intention is to enable analog and mixed-signal designers to assess CAD solution methods that are presented to them. On the other side, the intention is to enable developers of analog CAD tools to formulate and develop solution approaches for analog design centering and sizing.The structure of Analog Design Centering and Sizing is geared towards a combination of a reference book and a textbook. The formulations of tasks and solution approaches by mathematical means makes the book suitable as well for students dealing with analog design and design methodology.
Analgesia
Analgesics are among the oldest drugs described, albeit not necessarily for medicinaluse. Forexample,theSumeriansisolatedopioids(probablyfortheir euphoric effects) in the third millennium b. c. and the use of willow bark (salicin) for fever was ?rst reported in the eighteenth century. Both types of drugs are still in use, but today they are supplemented by a wide array of substances ranging from antidepressants to ion channel blockers. Not all of theseareprescribedbyphysicians. Manycompoundsaresoldoverthecounter and thus available to the public for self-medication. As a result, analgesics are also the most misused class of drugs and are the culprit for a multitude of healthproblemsdueto untoward sideeffects. Thisvolumeattemptstosummarizethecurrentstateofknowledgeonme- anisms underlying the various effects of these drugs, their side effect pro?les, and their indications and contraindications in clinical use.
Anaesthesia, pain, intensive care and emergency medicine A.P.I.C.E. ; Proceedings of the 21st Postgraduate Course in Critical Medicine: Venice-Mestre, Italy - November 10-13, 2006
Developing sectors in the Intensive Care field – and in Critical Care Medicine in general – require specific levels of competence having a same common denominator: an in-depth knowledge of human pathophysiology. Although this volume presents plenty of topics in constant evolution, as witnessed by the collection of chapters compiled by several researchers, this edition includes, in particular, fields in which decision-making at the patient’s bedside prevails over theoretical argumentation. In other words, the first and foremost message this edition wants to provide is for the reader to focus his/her attention on evidence-based medicine.
Anaesthesia, pain, intensive care and emergency medicine - A.P.I.C.E. ; Proceedings of the 20th Postgraduate Course in Critical Care Medicine, Trieste, Italy - November 18-21, 2005
The main objective of modern medicine has been the acquisition of increased skills and highly specialised knowledge in the various disciplines. At the same time, there has been a progressive multidisciplinary and multi-professional interest in acute disease conditions that place the patient in potential or real life-threatening situations. The state of the art of intensive medicine comprises a wide range of sophisticated interventions and collaboration between different medical disciplines, both of which give the patient access to the most advanced forms of treatment that are currently available.
An Undergraduate Primer in Algebraic Geometry
This book consists of two parts. The first is devoted to an introduction to basic concepts in algebraic geometry: affine and projective varieties, some of their main attributes and examples. The second part is devoted to the theory of curves: local properties, affine and projective plane curves, resolution of singularities, linear equivalence of divisors and linear series, Riemann–Roch and Riemann–Hurwitz Theorems.The approach in this book is purely algebraic. The main tool is commutative algebra, from which the needed results are recalled, in most cases with proofs. The prerequisites consist of the knowledge of basics in affine and projective geometry, basic algebraic concepts regarding rings, modules, fields, linear algebra, basic notions in the theory of categories, and some elementary point–set topology.
An Introduction to the Heisenberg Group and the Sub-Riemannian Isoperimetric Problem
This book provides an introduction to the basics of sub-Riemannian differential geometry and geometric analysis in the Heisenberg group, focusing primarily on the current state of knowledge regarding Pierre Pansu's celebrated 1982 conjecture regarding the sub-Riemannian isoperimetric profile.
An Introduction to Navier-Stokes Equation and Oceanography
The Introduction to Navier-Stokes Equation and Oceanography corresponds to a graduate course in mathematics, taught at Carnegie Mellon University in the spring of 1999. Comments were added to the lecture notes distributed to the students, as well as short biographical information for all scientists mentioned in the text, the purpose being to show that the creation of scientific knowledge is an international enterprise, and who contributed to it, from where, and when. The goal of the course is to teach a critical point of view concerning the partial differential equations of continuum mechanics, and to show the need for developing new adapted mathematical tools.
An Introduction to Manifolds
Manifolds, the higher-dimensional analogs of smooth curves and surfaces, are fundamental objects in modern mathematics. Combining aspects of algebra, topology, and analysis, manifolds have also been applied to classical mechanics, general relativity, and quantum field theory. In this streamlined introduction to the subject, the theory of manifolds is presented with the aim of helping the reader achieve a rapid mastery of the essential topics. By the end of the book the reader should be able to compute, at least for simple spaces, one of the most basic topological invariants of a manifold, its de Rham cohomology. Along the way the reader acquires the knowledge and skills necessary for further study of geometry and topology.
An Introduction to Knowledge Engineering
Knowledge Engineering refers to the development of systems that use knowledge, rather than data, to solve many novel computing problems. This is achieved by the application of computing techniques, closely associated with human cognitive processes, for transforming data into knowledge. An Introduction to Knowledge Engineering presents a simple but detailed exploration of current and established work in the field.
An introduction to description logics
Designed so that domain knowledge can be described and so that computers can reason about this knowledge. DLs have recently gained increased importance since they form the logical basis of widely used ontology languages, in particular the web ontology language OWL. Written by four renowned experts, this is the first textbook on description logics. It is suitable for self-study by graduates and as the basis for a university course. Starting from a basic DL, the book introduces the reader to their syntax, semantics, reasoning problems and model theory and discusses the computational complexity of these reasoning problems and algorithms to solve them.
An Introduction to continuous-time stochastic processes : Theory, models, and applications to finance, biology, and medicine
This book is introduction to the theory of continuous-time stochastic processes. A balance of theory and applications, the work features concrete examples of modeling real-world problems from biology, medicine, industrial applications, finance, and insurance using stochastic methods. No previous knowledge of stochastic processes is required. Key topics covered include: * Interacting particles and agent-based models: from polymers to ants * Population dynamics: from birth and death processes to epidemics * Financial market models: the non-arbitrage principle * Contingent claim valuation models: the risk-neutral valuation theory * Risk analysis in insurance
An Illustrated Guide to Furniture History
Provides upper-level students and instructors with an alternative visual analytical approach to learning about furniture history from Antiquity to Postmodernism. Following an immersive teaching model, it presents a Nine-Step Methodology to help students strengthen their visual literacy and quickly acquire subject area knowledge. Moving chronologically through key periods in furniture history and interior design, such as the Renaissance, the Arts and Crafts Movement, and Modernism, it traverses Europe to America to present a comprehensive foundational guide to the history of furniture design.
Amino acid biosynthesis : Pathways, regulation and metabolic engineering
Amino Acids Biosynthesis presents the current knowledge of fundamental as well as applied microbiology of amino acids. Topics discussed are the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The characterization of the control mechanisms of amino acid biosynthesis has revealed insights into principles of genetic and biochemical regulation, such as transcriptional regulators and a new class of regulatory elements, the riboswitch. The volume further deals with the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and, particularly, as food and feed additives.
Ambisonics : A Practical 3D Audio Theory for Recording, Studio Production, Sound Reinforcement, and Virtual Reality
Provides a concise explanation of the fundamentals and background of the surround sound recording and playback technology Ambisonics. It equips readers with the psychoacoustical, signal processing, acoustical, and mathematical knowledge needed to understand the inner workings of modern processing utilities, special equipment for recording, manipulation, and reproduction in the higher-order Ambisonic format. The book comes with various practical examples based on free software tools and open scientific data for reproducible research. The book includes an extensive mathematical appendix. The book offers readers a deeper understanding of Ambisonic technologies, and will especially benefit scientists, audio-system and audio-recording engineers.
Alzheimer : 100 Years and Beyond
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4th, 1906 in Tübingen. The celebratory event, "Alzheimer 100 Years and Beyond" organized on the initiative of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, at the very site of the original lecture, namely the Institute of Psychiatry at the University of Tübingen in Germany from November 2nd to 5th, 2006, was the highlight of the Alzheimer Year. Over the last century of Alzheimer research (1906-2006), remarkable progress has been achieved. Most of the authors of the major discoveries and the people involved in research in this field will present, during the meeting and in this volume, the pioneering research explaining the conditions under which they were conducted. The goal of this book is to honor the work accomplished, to summarize the most important knowledge and to provide material for the history of science.
Alvar Aalto : Das Gesamtwerk = L'oeuvre complète = The Complete Work ; 3 Vol.s
Aalto's designs encompassed the fields of painting, architecture, sculpture, and furniture, and are some of the most beautiful and original of modern times. His combination of an interest in natural, organic shapes with the modernist mandates of form and light in its purest aspects makes him one of the acknowledged masters of modern architecture, along with Le Corbusier and Frank Lloyd Wright.



















