الصفحة 70
الصفحة 70
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Anthracycline Chemistry and Biology I : Biological Occurence and Biosynthesis, Synthesis and Chemistry

"This book … covers many different aspects of the origin, chemistry, and biosynthesis of one of the oldest but most important classes of anticancer agents. … In summary, the book is nicely produced, very well edited, and should serve as a valuable source of information … . This book will serve as an inspiration for scientists and students in the areas of chemistry, drug discovery, and biological evaluation. It should be an essential addition to institutional library collections … ."

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Anterior knee pain and patellar instability

This multidisciplinary book reviews the diagnosis and management of anterior knee pain and patellar instability in an eminently clinical and practical manner. The book reviews the therapeutic alternatives, both surgical and non-surgical, emphasizing the considerable importance of minimal intervention and non-surgical methods. Similarly, anterior knee pain following ACL reconstruction is covered in detail.

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Antennas & propagation for wireless communication systems ; 2nd ed.

Antennas and propagation are of fundamental importance to the coverage, capacity and quality of all wireless communication systems. This book provides a solid grounding in antennas and propagation, covering terrestrial and satellite radio systems in both mobile and fixed contexts. Building on the highly successful first edition, this fully updated text features significant new material and brand new exercises and supplementary materials to support course tutors. A vital source of information for practising and aspiring wireless communication engineers as well as for students at postgraduate and senior undergraduate levels, this book provides a fundamental grounding in the principles of antennas and propagation without excessive recourse to mathematics. It also equips the reader with practical prediction techniques for the design and analysis of a very wide range of common wireless communication systems.

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Another side of drugs

Drug interactions remain an important consequence of pharmacologic intervention. It is clear that the pharmacologic response of a drug can be markedly influenced by concurrent administration of another therapeutic agent or food. These interactions may result in a decreased therapeutic effect or in an increase in the amount and extent of untoward reactions. Despite the well-described and real clinical consequences of certain drug interactions, this aspect of patient care often continues to be overlooked.

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Anorexia nervosa and mood-enhancing foods

Anorexia nervosa (AN) is a serious mental illness characterized by failure to maintain normal weight and by overvalued ideas about the importance of body shape and weight. This study aims to discuss Anorexia nervosa and understand the pathophysiology to successfully fight this enigmatic illness and present the goal of the treatment for individuals with AN. The bi-directional influences between emotion and food consumption are discussed. Finally, we have searched in Future Directions and Treatment development of AN.

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Animals and the shaping of modern medicine : One health and its histories

This book breaks new ground by situating animals and their diseases at the very heart of modern medicine. In demonstrating their historical significance as subjects and shapers of medicine, it offers important insights into past animal lives, and reveals that what we think of as ‘human’ medicine was in fact deeply zoological.Each chapter analyses an important episode in which animals changed and were changed by medicine. Ranging across the animal inhabitants of Britain’s zoos, sick sheep on Scottish farms, unproductive livestock in developing countries, and the tapeworms of California and Beirut, they illuminate the multi-species dimensions of modern medicine and its rich historical connections with biology, zoology, agriculture and veterinary medicine. The modern movement for One Health – whose history is also analyzed – is therefore revealed as just the latest attempt to improve health by working across species and disciplines.

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Animal Models of T Cell-Mediated Skin Diseases

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases". Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.

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Anesthesia Considerations for the Oral and Maxillofacial Surgeon

Strengthens the margin of safety of office-based anesthesia administration by helping practitioners determine whether the patients they treat are good candidates for office-based anesthesia. This book is organized into three sections. The first section provides a review of the principles of anesthesia, including the pharmacology of anesthetic agents, local anesthesia, patient monitoring, preoperative evaluation, the airway, and management of emergencies and complications. The major organ systems of the body are reviewed in section two, and the most common comorbid conditions that affect these systems are described in terms of their pathophysiology, diagnosis, management, and anesthesia-related considerations. Section three reviews patient groups that warrant special consideration in the administration of office-based anesthesia, such as geriatric, pediatric, pregnant, and obese patients. Spiral-bound and featuring tabs for quick and easy reference, this important book belongs on the shelf of every clinician who provides anesthesia in the office setting.

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Anemia in the Elderly

Anemia is found in approximately 80% of elderly patients, most often caused by chronic disease and iron deficiency. Hemopoiesis is a crossroad for many aging-related events.Why do older patients become anemic When should a diagnostic work up of anemia be initiated in the older person? What are the clinical consequences of anemia? Can the treatment of anemia delay aging? Have erythropoietic growth factors played a role in age-related anemia? Who should receive an erythropoietin stimulating agent?When should the suspicion for Myelodysplastic Syndrome be ruled out and what are the clues?This book addresses these and many other important questions with a review of the most recent findings.

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Andrology for the Clinician

Andrology for the Clinician consists of two parts: In Part One, the busy clinician can easily find the problem-orientated information he or she needs on such issues as * Male factor fertility problems * Male contraception * Male genital tract infection and tumours Part Two contains in-depth subject-orientated information and adds important scientific background information to the recommendations received in Part One. Several leading experts have contributed to this work, which has been extensively subedited by world-renowned editors to ensure a well-structured didactic design and homogeneous content.

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Androgen Excess Disorders in Women

The field of androgen excess disorders has advanced substantially since the original publication of this book. The Androgen Excess Society (AES) was founded to bring together investigators in the field. A better understanding of the screening, progression, and molecular genetics of nonclassic adrenal hyperplasia (NCAH) has improved the clinical care and diagnostic accuracy of these patients. New criteria for the diagnosis of the polycystic ovary syndrome (PCOS) were proposed in Rotterdam, criteria that have resulted in controversy and, hopefully, initiation of new studies. The association of insulin resistance with PCOS has been strengthened, and the role of metformin in tre- ing the infertility of the PCOS has been validated. Risks for diabetes and, more cont- versially, cardiovascular disease in women with PCOS have received substantial investigation. Our understanding of the epidemiology and economic impact of these disorders has expanded, emphasizing their critical importance.

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Anatomy of the forehead, face, and neck: a dissection manual

Provides a detailed step-by-step approach to the dissection of the forehead, face, and neck, in a structural, layered approach. This dissection manual follows an atlas format, with color photographs from past professional lectures and classroom courses, as well as line drawings, enhancing descriptions. Clinical correlations are also interjected throughout to highlight the importance of individual anatomic structures. Chapters describe the preparation and storage of specimens and the dissection of the forehead and eyebrows, the midface, nose, ear, and lower face, and the neck.

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Anatomy : Regional, Surgical, and Applied

Presents a concise, accessible guide to regional and clinically applied anatomy, which clearly demonstrates to students the level of knowledge required for medical and healthcare-related curricula / Uses high-quality clinical and intraoperative images integrated into the text to emphasizes important topics through bullet points / Features logically arranged sections, each devoted to a body region or system, which includes a self-test quiz, with the single best answer and spotter-style questions

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Analyzing computer system performance with Perl::PDQ

Analyzing computer system performance is often regarded by most system administrators, IT professionals and software engineers as a black art that is too time consuming to learn and apply. Finally, this book by acclaimed performance analyst Dr. Neil Gunther makes this subject understandable and applicable through programmatic examples. The means to this end is the open-source performance analyzer Pretty Damn Quick (PDQ) written in Perl As the epigraph in this book points out, Common sense is the pitfall of performance analysis. The performance analysis framework that replaces common sense is revealed in the first few chapters of Part I. The important queueing concepts embedded in PDQ are explained in a very simple style that does not require any knowledge of formal probability theory. Part II begins with a full specification of how to set up and use PDQ replete with examples written in Perl. Subsequent chapters present applications of PDQ to the performance analysis of multicomputer architectures, benchmark results, client/server scalability, and Web-based applications.

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Analytical Ultracentrifugation VIII

This book presents a comprehensive collection of 21 contributions from leading scientists in this field covering a broad spectrum of topics and presenting recent progress concerning instrumentation, data analysis and modeling, biological systems, particles, colloids, synthetic macromolecules, interacting systems. Due to the versatility of this fascinating and powerful technique, information and original publications are widespread and comprehensive collections are rare. Therefore, this volume presents a valuable source for biologists, chemists, materials scientists, and physicists interested in most recent information, results and development related to this important analytical method.

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Analytical Chemistry : Theoretical and Metrological Fundamentals

Fundamentals of Analytical Chemistry are usually presented as a sum of chemical and physical foundations, laws, axioms and equations for analytical methods and procedures. In contrast, this book delivers a practice-oriented, general guiding theory valid for all methods and techniques. Starting with a closer look to analytical signals and their dependencies, all the important figures of merit characterizing the power of analytical procedures and the reliability of analytical results are discussed and quantified, such as sensitivity, precision, accuracy and ruggedness. Elements of signal theory, information theory, statistics and fundamentals of calibration are also presented for this aim.

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Analysis, Control and Optimization of Complex Dynamic Systems

Analysis, Control and Optimization of Complex Dynamic Systems gathers in a single volume a spectrum of complex dynamic systems related papers written by experts in their fields, and strongly representative of current research trends. Complex systems present important challenges, in great part due to their sheer size which makes it difficult to grasp their dynamic behavior, optimize their operations, or study their reliability. Yet, we live in a world where, due to increasing inter-dependencies and networking of systems, complexity has become the norm. With this in mind, the volume comprises two parts. The first part is dedicated to a spectrum of complex problems of decision and control encountered in the area of production and inventory systems. The second part is dedicated to large scale or multi-agent system problems occurring in other areas of engineering such as telecommunication and electric power networks, as well as more generic context.

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Analysis of Structures by Matrix Methods

Deals with the analysis of engineering structures made of skeletal members and covers the type of structures that are commonly used in practice. It builds up on the subject matter dealing with matrix algebra, analysis of bar elements, special forms of members, stability and vibration of structures, and pin-connected, rigid-plane, and 3D frames. It treats the important step of formulating the overall stiffness matrix of a structure in a systematic and straightforward manner and uses simple mathematical approaches wherever possible.

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Analysis and Synthesis of Logics : How to Cut and Paste Reasoning Systems

Starting with simple examples showing the relevance of cutting and pasting logics, the monograph develops a mathematical theory of combining and decomposing logics, ranging from propositional and first-order based logics to higher-order based logics as well as to non-truth functional logics. The theory covers mechanisms for combining semantic structures and deductive systems either of the same or different nature (for instance, two Hilbert calculi or a Hilbert calculus and a tableau calculus). The important issue of preservation of properties is extensively addressed. For instance, sufficient conditions are provided for a combined logic to be sound and complete when the original component logics are known to be sound and complete.

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Analysis and Simulation of Contact Problems

Contact mechanics was and is an important branch in mechanics which covers a broad field of theoretical, numerical and experimental investigations. In this carefully edited book the reader will obtain a state-of-the-art overview on formulation, mathematical analysis and numerical solution procedures of contact problems. The contributions collected in this volume summarize the lectures presented during the 4th Contact Mechanics International Symposium (CMIS) held in Hannover, Germany, 2005, by leading scientists in the area of contact mechanics.

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