الصفحة 7
الصفحة 7
Computer Aided Pharmaceutics and Drug Delivery : An Application Guide for Students and Researchers of Pharmaceutical Sciences
Examines the role of computer-assisted techniques for discovering, designing, optimizing and manufacturing new, effective, and safe pharmaceutical formulations and drug delivery systems. The book discusses computational approaches, statistical modeling and molecular modeling for the development and safe delivery of drugs in humans. The application of concepts of QbD (Quality by Design), DoE (Design of Experiments), artificial intelligence and in silico pharmacokinetic assessment/simulation have been made a lot easier with the help of commercial software and expert systems. This title provides in-depth knowledge of such useful software with illustrations from the latest researches. The book also fills in the gap between pharmaceutics and molecular modeling at micro, meso and maro scale by covering topics such as advancements in computer-aided Drug Design (CADD), drug-polymer interactions in drug delivery systems, molecular modeling of nanoparticles and pharmaceutics/bioinformatics.
Computational Multiscale Modeling of Fluids and Solids : Theory and Applications
The book includes the micro-scale, the meso-scale and the macro-scale. The chapters follow this classification. The book will explain in detail many tricks of the trade of some of the most important methods and techniques that are used to simulate materials on the perspective levels of spatial and temporal resolution. Case studies are occasionally included to further illustrate some methods or theoretical considerations. Example applications for all techniques are provided, some of which are from the author’s own contributions to some of the research areas. Methods are explained, if possible, on the basis of the original publications but also references to standard text books established in the various fields are mentioned.
Computational Mechanics of Composite Materials : Sensitivity, Randomness and Multiscale Behaviour
The Engineering Materials and Processes series focuses on all forms of materials and the processes used to synthesise and formulate them as they relate to the various engineering disciplines. The series deals with a diverse range of materials: ceramics; metals (ferrous and non-ferrous); semiconductors; composites, polymers biomimetics etc. Each monograph in the series will be written by a specialist and will demonstrate how enhancements in materials and the processes associated with them can improve performance in the field of engineering in which they are used.
Computational Materials Chemistry : Methods and Applications
As a result of the advancements in algorithms and the huge increase in speed of computers over the past decade, electronic structure calculations have evolved into a valuable tool for characterizing surface species and for elucidating the pathways for their formation and reactivity. It is also now possible to calculate, including electric field effects, STM images for surface structures. To date the calculation of such images has been dominated by density functional methods, primarily because the computational cost of - curate wave-function based calculations using either realistic cluster or slab models would be prohibitive. DFT calculations have proven especially valuable for elucidating chemical processes on silicon and other semiconductor surfaces. However, it is also clear that some of the systems to which DFT methods have been applied have large non-dynamical correlation effects, which may not be properly handled by the current generation of Kohn-Sham-based density functionals. For example, our CASSCF calculations on the Si(001)/acetylene system reveal that at some geometries there is extensive 86 configuration mixing. This, in turn, could signal problems for DFT cal- lations on these systems.
Computational Chemistry and Molecular Modeling : Principles and Applications
The gap between introductory level textbooks and highly specialized monographs is filled by this modern textbook. It provides in one comprehensive volume the in-depth theoretical background for molecular modeling and detailed descriptions of the applications in chemistry and related fields like drug design, molecular sciences, biomedical, polymer and materials engineering. Special chapters on basic mathematics and the use of respective software tools are included.
Colloids for Nano- and Biotechnology
This volume contains a selection of the papers presented at the 9th Conference on Colloid Chemistry. A colloid chemical approach to nano- and biotechnology was one of the main topics of the meeting held in Siófok, Hungary in October 2007. It was organized by the Hungarian Chemical Society in cooperation with leading Hungarian universities and the Hungarian Academy of Sciences. The contributions demonstrated the progress of the field and supported that "The world of neglected dimensions" should not be neglected at all in modern material sciences and technologies. This volume is intended for professionals dealing with fundamental research or development of industrial applications, who encounter colloids, nanostructures, and interfacial phenomena during their work.
Materials Syntheses : A Practical Guide
Materials syntheses are generally more complex than syntheses of inorganic or organic compounds, and specific characterization methods play a more important role. Materials synthesis protocols often suffer from unclarities, irreproducibility, lack in detail and lack in standards. The need to change this situation is the main motivation for this book. A number of detailed protocols has been collected, ranging from organic polymers to carbonaceous and ceramic materials, from gels to porous and layered materials and from powders and nanoparticles to films. Preparation methods include intercalation and flux methods, sol-gel processing, templating methods for porous materials, sonochemistry or spray pyrolysis.
Materials science for dentistry
A standard resource for undergraduate and postgraduate courses in dentistry. It provides fundamental coverage of the materials on which dentistry depends, covering the structure and chemistry that govern the behavior and performance of materials. Particular classes of materials include gypsum, polymers, acrylic, cements, waxes, ceramics and metals. Other chapters review surfaces, corrosion, mixing, casting, cutting and bonding, and mechanical testing. This updated edition, which includes substantial chapters on chemistry, has been extensively revised with new material on temporary restoration resins, hydraulic silicate cements and the practical aspects of wetting surfaces. Mindfully written to provide explanations for behavior, formulation, clinical and laboratory instructions and procedures, there is no comparable resource for researchers, students, teachers and practitioners in the field of dentistry.
Materials Handbook : A Concise Desktop Reference
The unique and practical Materials Handbook (second edition) provides quick and easy access to data on the physical and chemical properties of all classes of materials. The second edition has been much expanded to include whole new families of materials while many of the existing families are broadened and refined with new material and up-to-date information. Particular emphasis is placed on the properties of common industrial materials in each class.
Materials for Springs
“Materials for springs” is basically intended for engineers related to spring materials and technologies who graduated from metallurgical or mechanical engineering courses in technical high school, or in other higher engineering schools, as well as those who are related to the purchase or sales of spring materials. The first chapter introduces into the fundamental selection processes of spring materials including the information sources on materials database. It is followed by the basic mechanisms and theories of spring failures such as fatigue fracture, creep/stress relaxation and stress corrosion cracking of metallic materials.
Materials Chemistry
"Written to fill the need for a textbook that addresses inorganic-, organic-, and nano-based materials from a structure vs. property treatment, Materials Chemistry aims to provide a suitable breadth and depth coverage of the rapidly evolving materials field - in a concise format. This modern treatment offers innovative coverage and practical perspective throughout.
Marine bioactive molecules for biomedical and pharmacotherapeutic application
Explores cutting-edge research on the discovery and application of marine bioactive molecules for biomedical and pharmacotherapeutic purposes. The book begins by delving into the bioprospection of marine sponge microbiomes for bioactive metabolites using advanced metagenomics tools. It then explores metagenome mining approaches for the discovery of marine microbial natural products. The use of marine-derived fungi as a source of anticancer secondary metabolites is also discussed. The book then turns to the biomedical applications of marine-derived biomaterials, including marine biopolymers in tissue engineering and regenerative medicine. Marine-derived pharmaceuticals and polymeric nanostructures for cancer treatment are also examined.
Machining: Fundamentals and Recent Advances
Machining is one of the most important manufacturing processes. Parts manufactured by others processes often require further operations before the product is ready for application. Machining is the broad term used to describe the removal of material from a work-piece. Machining processes can be applied to work metallic and non-metallic materials such as polymers, wood, ceramics and composites.
Lymphocyte Signal Transduction
Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational modifications, lead to the activation of transcription factors that mediate cellular differentiation and growth, effector cell functions, and apoptotic cell death. Several investigators from various parts of the world convened at the 3rd Lymphocyte Signal Transduction Workshop in Crete, Greece from May 27 to June 1, 2005 to discuss their most recent findings in leukocyte signaling. This volume represents a collection of topics discussed during the conference.
Liquid Crystalline Functional Assemblies and Their Supramolecular Structures
This book presents critical reviews of the present position and future trends in modern chemical research concerned with chemical structure and bonding. It contains short and concise reports, each written by the world's renowned experts.
Light-Associated Reactions of Synthetic Polymers
This book presents a range of reactions and materials with some of the most exciting current and future applications. It includes a brief introduction to photochemistry; in-depth discussion of photosensitizers, photoinititiators, and the processes of light curing and crosslinking; listing of light responsive polymers and their uses; and a discussion of polymeric materials for use in non-linear optics.
Light Scattering from Polymer Solutions and Nanoparticle Dispersions
Light scattering is a very powerful method to characterize the structure of polymers and nanoparticles in solution. Recent technical developments have strongly enhanced the possible applications of this technique, overcoming previous limitations like sample turbidity or insufficient experimental time scales. However, despite their importance, these new developments have not yet been presented in a comprehensive form. In addition, and maybe even more important to the broad audience, there lacks a simple-to-read textbook for students and non-experts interested in the basic principles and fundamental techniques of light scattering. As part of the Springer Laboratory series, this book tries not only to provide such a simple-to-read and illustrative textbook about the seemingly very complicated topic of light scattering from polymers and nanoparticles in dilute solution, but also intends to cover some of the newest technical developments in experimental light scattering.
Layered Double Hydroxides
Both experimental and theoretical studies of nearly every aspect of the LDH structure are discussed, including the range of metal cations and interlayer anions, M 3+ /M 2+ ratios, LDH polytypes, arrangement of the "interlayer" anions and water molecules, molecular modeling and molecular dynamics simulations, and the long- and short-range order in both the layers and interlayer galleries. Of especial value is the treatment of the more detailed aspects of the LDH structure that are still unresolved.
IUTAM symposium on theoretical, computational and modelling aspects of inelastic media ; Proceedings of the IUTAM Symposium held at Cape Town, South Africa, January 14–18, 2008
Comprises papers based on some of the talks presented at the IUTAM Symposium of the same name, held in Cape Town, January 14-18, 2008. This volume treats cutting-edge issues in modelling, the behaviour of various classes of inelastic media, and associated algorithms for carrying out computational simulations. A key feature of the contributions are works directed at modelling behaviour at the meso and micro-scales, and at bridging the micro-macro scales.
IUTAM Symposium on Multiscale Modelling of Damage and Fracture Processes in Composite Materials ; Proceedings of the IUTAM Symposium held in Kazimierz Dolny, Poland, 23-27 May 2005
This volume constitutes the Proceedings of the IUTAM Symposium. The main aim of the Symposium was to discuss the basic principles of damage growth and fracture processes in different types of composites: ceramic, polymer and metal matrix composites, cement and bituminous composites and wood. Nowadays, it is widely recognized that important macroscopic properties like the macroscopic stiffness and strength, are governed by processes that occur at one to several scales below the level of observation starting from nanoscale.
