الصفحة 7
الصفحة 7
Calixarenes in the Nanoworld
Calixarenes have been widely exploited in all areas of supramolecular chemistry over the past three decades and many recent developments have concerned their applications in the production of chemical entities with the dimensions of nanometres, as in "nanochemistry".Calixarenes in the Nanoworld Relates calixarenes to nanochemistry – key information for industries engaged in the production of high-tech materials. Provides a timely review of both what is known and the exciting prospects provided by calixarenes, Contains several review articles which define the importance of calixarenes as reagents in nanochemistry.
Brilliant light in life and material sciences
This book aim to create a synchrotron radiation facility, CANDLE, as an international laboratory for advanced research in life and material sciences. About 50 researchers from NATO, partner countries and Armenia gathered at Yerevan to discuss modern trends in developments of advanced light sources with high spectral brilliance and applications in basic and applied research in a wide range of fields. Research with high brilliant photon beams are used, for example for practical applications in pharmacy, electronics and nanotechnology. Such practical relevance promoted the design and construction of now more than 50 such facilities worldwide. Overview and specialized talks on the status and highlights of newly constructed light sources (ALBA, SPEAR3, European XFEL Facility, Siberian Synchrotron Radiation Center, CANDLE), on instrumentation and development of experimental techniques, and frontier research in life and material sciences using synchrotron radiation have been presented.
Biophysical characterization of functional peptides
Presents reproducible and step-by-step procedures for the peptide synthesis, their characterization and applications. The volume includes an introductory section on in silico modelling of new peptide molecules, Molecular Dynamics Simulations, Docking, Electrostatic fingerprinting of peptides, and other modelling tools for peptide designing and optimization. Further, it covers protocols for the solid phase peptide synthesis, chromatographic and mass spectrometric characterization of peptides. Importantly, it covers methods for biophysical characterizations of peptides for their potential applications as drug delivery vehicles, peptide nano-assembly, bionanocatalysis, protein aggregation diseases, and peptide-based anti-bacterial.
Bionanotechnology : Proteins to Nanodevices
Bionanotechnology is the key integrative technology of the 21st century and aims to use the knowledge, gathered from the natural construction of cellular systems, for the advancement of science and engineering. Investigating the topology and communication processes of cell parts can lead to invention of novel biological devices with exciting applications. Though microscale to nanoscale research offers an excellent space for the development of futuristic technologies, a number of challenges must be overcome. Due to paucity of a dedicated literature on the protein based nanodevices we bring you this monograph that combines collective research works of scientists probing into this fascinating universe of bionanotechnology. The monograph has been written with an aim of surveying engineering design principles of biomolecular nanodevices, prototype nanodevices based on redox proteins, bacteriorhodopsins and natural fibers, and touching upon the future developments in the field.
BioNanoFluidic MEMS
BioNanoFluidic MEMS explains nanofabrication and nanomaterials synthesis suitable for the development of biosensors. The fundamentals initiate an awareness for engineers and scientists who would like to develop and implement novel biosensors for various applications. In addition, the material covered includes: BioNanoFluidic MEMS connection between the interdisciplinary nature of BioNanoFluidics and MEMS BioNanoFluidics and sensor technology including Micro-Mechanical Sensors and Chemical Sensor Technologies ands-on steps for implementation of biosensor fabrication including a discussion of the clean room lithography process and etching, microsensor systems lamination, PDMS moulding, parylene deposition, and others Interconnection between the interdisciplinary nature of BioNanoFluidics and MEMS BioNanoFluidics and sensor technology including Micro-Mechanical Sensors and Chemical Sensor Technologies
BioMEMS and biomedical nanotechnology ; Vol. IV : Biomolecular Sensing, Processing and Analysis
This volume contains 18 chapters focused on ‘Biomolecular Sensing, Processing and Analysis’, written by experts in the field of BioMEMS and biomedical nanotechnology. The chapters are groups into three broad categories of Sensors and Materials, Processing and Integrated Systems, and Microfluidics.Prof. Taun Vo-Dinh from Oakridge National Labs begins the Sensors and Materials section by providing a review of biosensors and biochips. This review is followed by an example of mechanical cantilever sensor work described by Prof. Arun Majumdar’s group at UC Berkeley and Prof. Tom Thundat at Oakridge National Laboratory.
BioMEMS and biomedical nanotechnology ; Vol. III : Therapeutic Micro/Nanotechnology
The human body is composed of structures organized in a hierarchical fashion: from biomolecules assembled into polymers, to multimeric assemblies such as cellular or-ganelles, to individual cells, to tissues, to organ systems working together in health and disease- each dominated by a characteristic length scale. Decades of science and engineer-ing are now converging to provide tools that enable the orderly manipulation of biological systems at previously inaccessible, though critically important, length scales (<100 mi-crons). Thus, the approaches described in this volume provide a snapshot of how micro-and nanotechnologies can enable the investigation, prevention, and treatment of human disease.The volume is divided into three parts. The first part, Cell-based therapeutics; cov- ers the merger of cells with micro- and anosystems for applications in regenerative medicine spanning the development of novel nanobiomaterials.
BioMEMS and biomedical nanotechnology ; Vol. II : Micro/Nano Technologies for Genomics and Proteomics
Numerous miniaturized DNA microarray, DNA chip, Lab on a Chip and biosensor devices have been developed and commercialized. Such devices are improving the way many impor-tant genomic and proteomic analyses are performed in both research and clinical diagnostic laboratories. The development of these technologies was enabled by a synergistic combina-tion of disciplines that include microfabrication, microfluidics, MEMS, organic chemistry and molecular biology. Some of these new devices and technologies utilize sophisticated mi-crofabrication processes developed by the semiconductor industry.
BioMEMS and Biomedical Nanotechnology : Vol. I: Biological and Biomedical Nanotechnology
Abe Lee has been working on micro/ and nanotechnology for biomedical and biotech applications since 1992. His recent research focuses on the development of integrated micro and nano fluidic chip processors for the following applications: point-of-care diagnostics, "smart" nanomedicine for early detection and treatment, stem cell biology and therapeutics, the synthesis of novel and pure materials, and biosensors to detect environmental and terrorism threats. Jim Lee's research interest includes BioMEMS/NEMS, and polymer micro/nanotechnology. In the last 4 years, he has over 20 refereed journal publications, 2 book chapters, and 5 patents in these areas. He is now leading an NSF Nanoscale Science and Engineering Center for Affordable Nanoengineering of Polymer Biomedical Devices at OSU.
Biomedical applications and toxicity of nanomaterials
Covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
Biomaterials and bionanotechnology ; 1st ed.
Examines the current state of the field within pharmaceutical sciences and concisely explains the history of biomaterials including key developments. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biomaterials and bionanotechnology within drug discovery and drug development. Each chapter delves into a particular aspect of this fast-moving field to cover the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable dosage form, with particular focus on biomaterials and bionanomaterials. This book provides a comprehensive examination suitable for researchers working in the pharmaceutical, cosmetics, biotechnology, food and related industries as well as advanced students in these fields.
Bio-Applications of Nanoparticles
In this edited book, we highlight the central players in the Bionanotechnology field, which are the nanostructures and biomolecules. The book starts by describing how nanostructures are synthesized and by describing the wide variety of nanostructures available for biological research and applications. Also shown are the techniques used to synthesize a wide variety of biological molecules. Next, there is a focus on the assembly of nanostructures with biological molecules, which could lead to the design of multi-functional nanosystems. In the following chapters, examples of the unique properties of nanostructures are provided along with the current applications of these nanostructures in biology and medicine. Some applications include the use of gold nanoparticles in diagnostic applications, quantum dots and silica nanoparticles for imaging, and liposomes for drug delivery. In the final chapters of the book, the toxicity of nanostructures are described. This book provides broad examples of current developments in Bionanotechnology research and would be an excellent introduction to the field.
Automated nanohandling by microrobots
Automated Nanohandling by Microrobots introduces an actuation principle for such microrobots and presents a new robot design. Different aspects of this research field regarding the hardware and software implementation of the system components, including the sensory feedback for automated nanohandling, are discussed in detail. Extensive applications of the microrobot station for nanohandling, nano-characterization and nanostructuring are provided, together with the experimental results.
Aulton's pharmaceutics : The design and manufacture of medicines
Offers a complete course in one book for students in all years of undergraduate pharmacy and pharmaceutical sciences degrees. Thoroughly revised, updated and extended by experts in their fields and edited by Professors Kevin Taylor and Michael Aulton, this new edition includes the science of formulation, pharmaceutical manufacturing and drug delivery. All aspects of pharmaceutics are covered in a clear and readily accessible way and extensively illustrated throughout, providing an essential companion to the entire pharmaceutics curriculum from day one until the end of the course. Fully updated throughout, with the addition of new chapters, to reflect advances in formulation and drug delivery science, pharmaceutical manufacturing and medicines regulation Designed and written for newcomers to the design and manufacture of dosage forms Relevant pharmaceutical science covered throughout Includes the science of formulation and drug delivery Reflects current practices and future applications of formulation and drug delivery science to small drug molecules, biotechnology products and nanomedicines Key points boxes throughout Over 400 online multiple choice questions
Atomic Force Microscopy, Scanning Nearfield Optical Microscopy and Nanoscratching : Application to Rough and Natural Surfaces
Making a clear distinction is made between nano- and micro-mechanical testing for physical reasons, this monograph describes the basics and applications of the supermicroscopies AFM and SNOM, and of the nanomechanical testing on rough and technical natural surfaces in the submicron range down to a lateral resolution of a few nm. New or improved instrumentation, new physical laws and unforeseen new applications in all branches of natural sciences (around physics, chemistry, mineralogy, materials science, biology and medicine) and nanotechnology are covered as well as the sources for pitfalls and errors.
Applied scanning probe methods IX : Characterization
The success of the Springer Series Applied Scanning Probe Methods I–VII and the rapidly expanding activities in scanning probe development and applications worldwide made it a natural step to collect further speci c results in the elds of development of scanning probe microscopy techniques (Vol. VIII), characterization (Vol. IX), and biomimetics and industrial applications (Vol. X). These three volumes complement the previous set of volumes under the subject topics and give insight into the recent work of leading specialists in their respective elds. Following the tradition of the series, the chapters are arranged around techniques, characterization and biomimetics and industrial applications. Volume VIII focuses on novel scanning probe techniques and the understanding of tip/sample interactions. Topics include near eld imaging, advanced AFM, s- cializedscanningprobemethodsinlifesciencesincludingnewselfsensingcantilever systems, combinations of AFM sensors and scanning electron and ion microscopes, calibration methods, frequency modulation AFM for application in liquids, Kelvin probe force microscopy, scanning capacitance microscopy, and the measurement of electrical transport properties at the nanometer scale.
Applications of nanotechnology in drug discovery and delivery
Presents complete coverage of the application of nanotechnology in the discovery of new drugs and efficient target delivery of drugs. The book highlights recent advances of nanotechnology applications in the biomedical sciences, starting with chapters that provide the basics of nanotechnology, nanoparticles and nanocarriers. Part II deals with the application of nanotechnology in drug discovery, with an emphasis on enhanced delivery of pharmaceutical products, with Part III discussing toxicological and safety issues arising from the use of nanomaterials
Advances of novel formulations in drug delivery
This is an endeavor to bring all the nanotechnology-based drug carriers under the umbrella of a single text. The drug carriers made up using natural as well as synthetic polymers are described in detail. The drug carriers include (though not limited to) particulates, vesicular, dendrimers, quantum dots, carbon nano tubes, nanocrystals, nanoemulsions, nanofibers
Advances in Fracture Research : Honour and plenary lectures presented at the 11th International Conference on Fracture (ICF11), held in Turin, Italy, on March 20-25, 2005
Biological materials are bottom-up designed systems formed from billions of years of natural evolution. In the long course of Darwinian competition for survival, nature has evolved a huge variety of hierarchical and multifunctional systems from nucleic acids, proteins, cells, tissues, organs, organisms, animal communities to ecological s- tems. Multilevel hierarchy a rule of nature. The complexities of biology provide an opportunity to study the basic principles of hierarchical and multifunctional s- tems design, a subject of potential interest not only to biomedical and life sciences, but also to nanosciences and nanotechnology. Systematic studies of how hierarchical structures in biology are related to their functions and properties can lead to better understanding of the effects of aging, diseases and drugs on tissues and organs, and may help developing a scienti?c basis for tissue engineering to improve the standard of living.
Advances in dental implantology using nanomaterials and allied technology applications
Discusses how nanotechnology has influenced the provision of implant treatment from surgery to prosthetic reconstruction and post treatment biological complications. It aims to present both the nanotechnology and allied research along with the clinical concepts of almost every different aspect of implantology in one volume.
