الصفحة 7
الصفحة 7
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Benchmarking, Temporal Distribution, and Reconciliation Methods for Time Series

This book discusses the statistical methods most often applied for such adjustments, ranging from ad hoc procedures to regression-based models. The latter are emphasized, because of their clarity, ease of application, and superior results. Each topic is illustrated with many real case examples. In order to facilitate understanding of their properties and limitations of the methods discussed, a real data example, the Canada Total Retail Trade Series, is followed throughout the book.This book brings together the scattered literature on these topics and presents them using a consistent notation and a unifying view.

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Bank capital and risk-taking : The impact of capital regulation, charter value, and the business cycle

The aim of this study is to contribute to this understanding by answering the following questions: How do banks adjust capital and risk after an increase in capital requirements? How do banks adjust their regulatory capital buffer over the business cycle? And what is the impact of banks' charter value on the regulatory capital buffer?

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Bacterial signal transduction : Networks and drug targets

Interactions among different TCSs enable one system to respond to multiple signals, which is important for bacteria to minutely adjust themselves to complex environmental changes. Such interactions are found or predicted in various bacteria in this book. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been brought to light. Reports on these develop› ments have been put together in this book, Bacterial Signal Transduction: Networks andDrug Targets. This book Offers an incentive for graduate students, academic scientists, and researchers in the pharmaceutical industry to further elucidate the TCS networks and apply them in the search for novel drugs.

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Assessment of climate change over the Indian Region : A report of the Ministry of Earth Sciences (MoES), Government of India

Discusses the impact of human-induced global climate change on the Indian subcontinent and regional monsoon, the adjoining Indian Ocean and the Himalayas. It also examines the regional climate change projections based on the climate models used by the IPCC Fifth Assessment Report (AR5) and national climate change modeling studies using the IITM Earth System Model (ESM) and CORDEX South Asia datasets

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Arguing Fundamental Rights

The book is unique in combining a challenging interpretation of one the foremost European conceptions of fundamental rights with the discussion of the pragmatics of constitutional adjudication.

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Architecture and modelbuilding : Concepts, methods, materials

Provides in-depth information Numerous practical tips, clear explanations, concrete examples Aims and Scope Architectural models are used at various stages of a project. As working models they support the design process: they are made up from time to time using simple materials, such as cardboard, without any attempt at accuracy, and continue to be adjusted and added to as the ideas and the design progress. The point here is to swiftly check a design idea, to allow it to be continued or dismissed. Presentational models are more involved; at this stage the design has been completed and the purpose of the model is to convey the ideas to the potential user in a clear and easy-to-understand way.

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Applied High-Speed Plate Penetration Dynamics

High-speed impact dynamics is of interest in the fundamental sciences, e.g., astrophysics and space sciences, and has a number of important applications in military technologies, homeland security and engineering.

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Analyzing T cell responses : How to analyze cellular immune responses against tumor associated antigens

Active specific immunotherapy is a promising but investigational modality in the management of cancer patients. Currently, several different cancer vaccine formulations such as peptides, proteins, antigen-pulsed dendritic cells, whole tumor cells, etc. in combination with various adjuvants and carriers are being evaluated in clinical trials (1-3). To determine the optimal cancer

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Algorithms in Bioinformatics : Theory and Implementation

Explores a comprehensive and insightful treatment of the practical application of bioinformatic algorithms in a variety of fields. Delivers a fulsome treatment of some of the main algorithms used to explain biological functions and relationships. It introduces readers to the art of algorithms in a practical manner which is linked with biological theory and interpretation. The book covers many key areas of bioinformatics, including global and local sequence alignment, forced alignment, detection of motifs, Sequence logos, Markov chains or information entropy. Other novel approaches are also described, such as Self-Sequence alignment, Objective Digital Stains (ODSs) or Spectral Forecast and the Discrete Probability Detector (DPD) algorithm. Readers will also benefit from the inclusion of: A detailed presentation of new methods, such as Self-sequence alignment, Objective Digital Stains and Spectral Forecast ; A treatment of sequence alignment, including local sequence alignment, global sequence alignment and forced sequence alignment with full implementations ; Discussions of position-specific weight matrices, including the count, weight, relative frequencies, and log-likelihoods matrices ; A detailed presentation of the methods related to Markov Chains as well as a description of their implementation in Bioinformatics and adjacent fields ; An examination of information and entropy, including sequence logos and explanations related to their meaning ; A chapter on philosophical transactions that allows the reader a broader view of the prediction process ; Extensive worked examples with detailed case studies that point out the meaning of different results

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Algorithms and data structures for massive datasets

Learn: Probabilistic sketching data structures for practical problems Choosing the right database engine for your application Evaluating and designing efficient on-disk data structures and algorithms Understanding the algorithmic trade-offs involved in massive-scale systems Deriving basic statistics from streaming data Correctly sampling streaming data Computing percentiles with limited space resources Algorithms and Data Structures for Massive Datasets reveals a toolbox of new methods that are perfect for handling modern big data applications. You'll explore the novel data structures and algorithms that underpin Google, Facebook, and other enterprise applications that work with truly massive amounts of data. These effective techniques can be applied to any discipline, from finance to text analysis. Graphics, illustrations, and hands-on industry examples make complex ideas practical to implement in your projects--and there's no mathematical proofs to puzzle over. Work through this one-of-a-kind guide, and you'll find the sweet spot of saving space without sacrificing your data's accuracy. About the Technology Standard algorithms and data structures may become slow--or fail altogether--when applied to large distributed datasets. Choosing algorithms designed for big data saves time, increases accuracy, and reduces processing cost.

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Algorithms and architectures for parallel processing ; 7th International Conference, ICA3PP 2007, Hangzhou, China, June 11-14, 2007, Proceedings

The improvements in computation and communication capabilities have enabled the creation of demanding applications in critical domains such as the environment, health, aerospace, and other areas of science and technology. Similarly, new classes of applications are enabled by the availability of heterogeneous large-scale distributed systems which are becoming available nowadays (based on technologies such as grid and peer-to-peer systems).Parallel computing systems exploit a large diversity of computer architectures, from supercomputers, shared-memory or distributed-memory multi processors, to local networks and clusters of p- sonal computers. With the recent emergence of multi core architectures, parallel computing is now set to achieve “mainstream” status. Approaches that have been advocated by parallel computing researchers in the past are now being utilized in a number of software libraries and hardware systems that are available for everyday use. Parallel computing ideas have also come to dominate areas such as multi user gaming (especially in the development of gaming engines based on “cell” arc- tectures).

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Algorithms – ESA 2007 ; 15th Annual European Symposium, Eilat, Israel, October 8-10, 2007, Proceedings

This book presented submissions in the engineering and applications track. The papers address all current subjects in algorithmics reaching from design and analysis issues of algorithms over to real-world applicat.

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AI in drug discovery

Constitutes the refereed proceedings of the First international workshop on ai in Drug Discovery, AIDD 2024, held as a part of the 33rd International Conference on Artificial Neural Networks, ICANN 2024, in Lugano, Switzerland, on September 19, 2024. These papers focus on various aspects of the rapidly evolving field of Artificial Intelligence (AI)-driven drug discovery in chemistry, including Big Data and advanced Machine Learning, eXplainable AI (XAI), Chemoinformatics, Use of deep learning to predict molecular properties, Modeling and prediction of chemical reaction data and Generative models.

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Advances in optical fiber communications

Given the increasing importance of a globally interconnected world, driven by modern digital services and the need for fast and reliable access to digital resources, communication networks are one of the key infrastructures in today’s society. In this scenario, fiber optics and optical devices play a leading role, as they allow for unprecedented growth in our capacity to cope with the ever-increasing traffic demand. Optical transmission solutions range from high-speed networks based on coherent detection and advanced modulation formats for long-haul-level communications, to networks still relying on traditional intensity modulation and direct detection receivers for short-reach communications, down to intra-data center scenarios.

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Advances in Mathematical Finance

This volume brings together a collection of chapters by some of the most distinguished researchers and practitioners in the fields of mathematical finance and financial engineering. Presenting state-of-the-art developments in theory and practice.

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Advances in databases and information systems ; 25th European Conference, ADBIS 2021, Tartu, Estonia, August 24–26, 2021, Proceedings

This book constitutes the proceedings of the 25th European Conference on Advances in Databases and Information Systems, ADBIS 2021, held in Tartu, Estonia, in August 2021. The 18 full papers presented together with 3 keynotes were carefully reviewed and selected from 70 submissions. The selected papers span a wide spectrum of topics in databases and related technologies, tackling challenging problems and presenting inventive and efficient solutions. They are organized in 5 sessions: patterns and events, social media and text mining, indexes, queries and constraints, high-dimensional data and data streams, and data integration.

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Advances in Breast Cancer Management, 2nd ed.

Advances in Breast Cancer Management, Second Edition will highlight many of the important advances that have transformed our understanding of the biology and therapeutics of breast cancer.

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Administrative law

Each book in this popular series offers a winning combination of text, examples, and explanations as it guides students to a more thorough understanding of the subject at hand for paralegal programs.

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A short guide to clinical pharmacokinetics

Consists of seven chapters that cover various aspects of pharmacokinetics and its clinical applications. The chapters are structured to provide clear objectives and keywords are bolded throughout the text to facilitate understanding. The topics covered include the significance of pharmacokinetics in clinical practice, factors affecting pharmacokinetic parameters, pharmacokinetic drug interactions, therapeutic drug monitoring, dosage adjustment in different population groups, the influence of hepatic diseases on pharmacokinetics and the impact of pharmacogenomics on pharmacokinetics and pharmacodynamics.

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A Practical Guide to Service Learning : Strategies for Positive Development in Schools

The ultimate goal for school psychologists, teachers, and other allied mental health and educational professionals is to ensure that all children are able to achieve academic success in the classroom. Still, a significant number of schoolchildren feel caught in an academic, social-emotional vortex that can be demoralizing, isolating, and disorienting. Some may be cognitively impaired. Others may simply be bored. Many are well-adjusted but overwhelmed with academic and extracurricular demands.

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