Methods of Celestial Mechanics ; Vol. II : Application to Planetary System, Geodynamics and Satellite Geodesy
G. Beutler's Methods of Celestial Mechanics is a coherent textbook for students as well as an excellent reference for practitioners. Volume II is devoted to the applications and to the presentation of the program system CelestialMechanics. Three major areas of applications are covered: (1) Orbital and rotational motion of extended celestial bodies. The properties of the Earth-Moon system are developed from the simplest case (rigid bodies) to more general cases, including the rotation of an elastic Earth, the rotation of an Earth partly covered by oceans and surrounded by an atmosphere, and the rotation of an Earth composed of a liquid core and a rigid shell (Poincaré model). (2) Artificial Earth Satellites. The oblateness perturbation acting on a satellite and the exploitation of its properties in practice is discussed using simulation methods (CelestialMechanics) and (simplified) first order perturbation methods. The perturbations due to the higher-order terms of the Earth's gravitational potential and resonant perturbations are considered thereafter. Special attention is paid to satellites of the Global Navigation Satellite Systems and to geostationary satellites. The characteristics of and models for the two most important non-gravitational forces, atmospheric drag and radiation pressure, are presented as well as the most relevant forces acting on high- and low-orbiting satellites. (3) Evolution of the Planetary System. The outer planetary system consisting of the planets Jupiter to Pluto is studied over long time intervals using simulation methods and spectral analysis (CelestialMechanics). The properties of the inner systems, in particular of the Earth's orbit, are made visible by integrating the entire system over long time intervals relevant for climate change. The distribution of minor planets and their orbital properties, regular orbits, and chaotic orbits are easily generated and analyzed using CelestialMechanics. The volume concludes with the discussion of important mathematical tools of the program system and of the principles of spectral analysis.
Methodology of Uniform Contract Law : The UNIDROIT Principles in International Legal Doctrine and Practice
In this book, the author examines uniform contract law comprehensively in all relevant areas of legal doctrine and practice and considers the barriers which exist toward it in modern nation states, namely in the German and English legal systems. She suggests ways in which these barriers can be overcome and develops an autonomous methodology of interpretation of transnational contract principles. The author wants to encourage the use of existing uniform transnational law rules, such as the UNIDROIT Principles of International Commercial Contracts, which are analysed here as an example.
Metathesis Polymerization
Clearly illustrated and demonstrated by the entire series of Advances in Polymer Science., the area of polymer science is a rapidly developing and growing field, strongly influencing other areas of chemistry. Among other polymerization techniques, those based on metathesis polymerization have experienced significant progress. With a rapidly developing armory of initiators on hand, one is now capable of polymerizing various types of functional monomers by metathesis-based techniques.The latest developments in all these areas of metathesis-based polymerizations are summarized in this book. It is designed to attract equally students and advanced scientists working in the areas of polymer science, physical, and organometallic chemistry by providing both extensive background information and up-to-date interdisciplinary knowledge. Special consideration has been given to the literature sections in order to facilitate further reading.
Metalearning : Applications to Automated Machine Learning and Data Mining
This book as one of the fastest-growing areas of research in machine learning, metalearning studies principled methods to obtain efficient models and solutions by adapting machine learning and data mining processes. This adaptation usually exploits information from past experience on other tasks and the adaptive processes can involve machine learning approaches. As a related area to metalearning and a hot topic currently, automated machine learning (AutoML) is concerned with automating the machine learning processes. Metalearning and AutoML can help AI learn to control the application of different learning methods and acquire new solutions faster without unnecessary interventions from the user.
Metal-Catalysed Reactions of Hydrocarbons
This unique book, drawing on the author’s lifetime experience, critically evaluates the extensive literature on the field of Metal-Catalysed Reactions of Hydrocarbons. Emphasis is placed on reaction mechanisms involving hydrogenation, hydrogenolysis, skeletal and positional isomerisation, and exchange reactions. The motivation for fundamental research in heterogeneous catalysis is to identify the physicochemical characteristics of active centres for the reaction being studied, to learn how these may be modified or manipulated to improve the desired behavior of the catalyst, and to recognize and control those aspects of the catalyst's structure that limit its overall performance. By restricting the subject of the book to hydrocarbons, Bond has progressively developed the subject matter to include areas of importance both to researchers and to those working in the industry.
Metaheuristics : Progress in Complex Systems Optimization
The aim of METAHEURISTICS: Progress in Complex Systems Optimization is to provide several different kinds of information: a delineation of general metaheuristics methods, a number of state-of-the-art articles from a variety of well-known classical application areas as well as an outlook to modern computational methods in promising new areas. Therefore, this book may equally serve as a textbook in graduate courses for students, as a reference book for people interested in engineering or social sciences, and as a collection of new and promising avenues for researchers working in this field.
Metabolomics : The frontier of systems biology
Metabolism is the sum of the chemical reactions in cells that produce life-sustaining chemical energy and metabolites. In the post-genome era, metabolism has taken on new significance for biological scientists: metabolites are the chemical basis of phenotypes that are final expressions of genomic information. This book covers research on metabolomics, ranging from the development of specialized chemical analytical techniques to the construction of databases and methods for metabolic simulation. The authors have been directly involved in the development of all the subject areas, including capillary electrophoresis, liquid chromatography, mass spectrometry, metabolic databases, and metabolic simulation. Breakthrough achievements and the future of metabolome studies are described, making this book a valuable source for researchers in metabolomics in diverse fields, such as plant, animal, cellular, microbial, pharmaceutical, medical, and genetic sciences.
Metabolome Analyses : Strategies for Systems Biology
Metabolome Analyses is intended as a follow-up to Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis (Kluwer, 2003). That text offered guidelines to currently available technology, bioinformatics and databases. Evidence was presented showing metabolic profiling as a valuable addition to genomics and proteomics strategies devoted to drug discovery and development. This book focuses on how metabolic profiling is being more comprehensively integrated with the other "omics" technologies. It provides more practical applications of such "panomics" or "Systems Biology" approaches. The expanding use of mass spectrometry as a measurement technology in metabolic profiling is addressed through demonstrated applications. The integration of metabolic profiling and proteomics is probably most developed for plant-based studies, which was not addressed in Volume 1. Other areas related to metabolic profiling continue to show significant development. These include database strategies and an increased acceptance by the pharmaceutical industry of metabolic profiling. Also covered is the use of in silico metabolic networks. Again the focus is primarily on the pharmaceutical industry but the importance of metabolic profiling to studies on human nutrition (a burgeoning area) is discussed.
Messenger RNA therapeutics
Focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs. In the past 30 years, extensive research and technological development in many areas have contributed to the emergence of in vitro transcribed mRNA as a therapeutic that has now reached clinical testing. Formulations that protect the mRNA from nucleases and accelerate its cellular uptake, combined with improvements to the mRNA molecules themselves, have been critical advancements for mRNAs to become viable therapeutics. Though once regarded as a serious impediment, the transient nature of mRNA technology is now considered a major advantage in making mRNA therapies safe and, ultimately, a potential game changer in the field of medicine. This new book in the RNA Technologies series provides a state-of-the-art overview on the emerging field of mRNA therapeutics covering essential strategies for formulation, delivery, and application. It also reviews the promising role in cancer immunotherapy, respiratory diseases, and chronic HBV infection and discusses RNA vaccines in light of the current COVID-19 pandemic. mRNA-based approaches have great potential to revolutionize molecular biology, cell biology, biomedical research, and medicine.
Meshfree Methods for Partial Differential Equations III
Meshfree methods for the numerical solution of partial differential equations are becoming more and more mainstream in many areas of applications. Their flexiblity and wide applicability are attracting engineers, scientists, and mathematicians to this very dynamic research area. This volume represents the state of the art in meshfree methods. It consists of articles which address the different meshfree techniques, their mathematical properties and their application in applied mathematics, physics and engineering.
Mental Health, Social Mirror
The essays in this volume reassert the centrality of research in mental health to sociology. First, they articulate the contributions that mental health research has made and can make to resolving key theoretical and empirical debates in important areas of sociological study. Second, they draw from mainstream theories and concepts to reconsider the potential of sociology to provide answers to critical questions regarding the social origins of and social responses to mental illness. As reflected in the title, the sociological study of mental health provides a reflection of the central processes that characterize our society.
Medical Treatment of Intoxications and Decontamination of Chemical Agents in the Area of Terrorist Attack
This book includes reports which were presented at a NATO Advanced Research Workshop (ARW) entitled?Medical Treatment of Intoxications and Decontamination of Chemical Agent in the Area of Terrorist Attack?. The focus of this workshop was assessment of scientific concepts and practical means for management of chemical agent casualties in the area of terrorist attack with emphasis on improving the medical treatment and decontamination. These problems were analyzed from an interdisciplinary perspective. The primary objective of the ARW was to provide countries in which chemical-defense systems are currently under development with the experience and expertise of those that are more advanced and/or have already been exposed and responded to a chemical-terrorist attack. . The main areas covered were: 1. new approaches in pre-treatment and prophylaxis of nerve agent intoxication; 2. diagnosis of exposure to chemical agents ; 3. therapy of chemical agent intoxication; 4. development of personal decontamination; 5. decontamination of intoxication with chemical agents.
Medical Reprints: 3D ed.
3D printing or additive manufacturing is a novel method of manufacturing parts directly from a digital model by using layer by layer material build-up approaches. This discovery is predicted to have the greatest impact on the future industries. Additive manufacturing has numerous applications in different areas including healthcare. Applications encompass many medical fields such as dentistry, surgery, and medical devices as well as the pharmaceutical field. Due to transplant donor deficiencies, ‘bioprinting’ has been invented to print biocompatible organs. Adding ‘time’ as a 4th dimension, 4D printing uses ‘smart materials’ to initiate the ‘smart drugs’ era.
Medical Pharmacology and Therapeutics
Provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA. This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class. Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines.
Medical Informatics : Knowledge Management and Data Mining in Biomedicine
Knowledge Management and Data Mining in Biomedicine covers the basic foundations of the area while extending the foundational material to include the recent leading-edge research in the field. The newer concepts, techniques, and practices of biomedical knowledge management and data mining are introduced and examined in detail. It is the research and applications in these areas that are raising the technical horizons and expanding the utility of informatics to an increasing number of biomedical professionals and researchers. These concepts and techniques are illustrated with detailed case studies.
Medical Applications of Colloids
This volume collects chapters dealing with significant topics in colloids and surfaces relevant to medical applications. The book will be of interest to scientists and practitioners in areas as diverse as medical diagnostics, drug formulations, X-ray photoelectron spectroscopy of biomaterials, and particle transport in human airways.
Medial Representations : Mathematics, Algorithms and Applications
The last half century has seen the development of many biological or physical theories that have explicitly or implicitly involved medial descriptions of objects and other spatial entities in our world. Simultaneously mathematicians have studied the properties of these skeletal descriptions of shape, and, stimulated by the many areas where medial models are useful, computer scientists and engineers have developed numerous algorithms for computing and using these models. We bring this knowledge and experience together into this book in order to make medial technology more widely understood and used.
Mechanics of Biological Tissue
The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book highlights some important research directions that combine mechanical sciences with exciting new developments in biology. This collection of papers should be of interest to theoretical, computational and experimental researchers and doctoral students in the area of biomechanics and in related areas of engineering, biology and medicine.
Measuring Professional Competence for the Teaching of Mathematical Modelling : A Test Instrument
This book presents a structural model and an associated test instrument designed to provide a detailed analysis of professional competences for teaching mathematical modelling. The conceptualisation is based on the COACTIV model, which describes aspects, areas and facets of professional competences of teachers. The manual provides an overview of the essential teaching skills in application-related contexts and offers the tools needed to capture these aspects. It discusses the objectives and application areas of the instrument, as well as the development of the test. In addition, it describes the implementation and evaluates the quality and results of the structural equation analysis of the model.
Mayo clinic infectious disease case review : With board-style questions and answers
Addresses many of the current-day illnesses seen by primary care clinicians and infectious diseases specialists. A case presentation format is used for all 54 chapters, and this framework serves as a wonderful educational tool that mirrors, in many respects, the objectives of a “case conference” format. The dozens of authors from different areas of our specialty have ensured that a robust clinical examination of specific infection syndromes has been included. In addition, the Question and Answer section solidifies the educational benefits for all levels and types of clinicians who seek an understanding of disease diagnosis, management, and prevention. A well-recognized characteristic of infectious diseases specialists is our focus on epidemiology, and this trait has served us well in developing successful clinical careers.



















