الصفحة 68
الصفحة 68
Pharmaceutical dosage forms and drug delivery : Revised and expanded
Completely revised and updated, this fourth edition elucidates the principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery - including emerging new biotechnology-based treatment modalities. The authors integrate aspects of physical pharmacy, chemistry, biology, and biopharmaceutics into drug delivery
Pharmaceutical cocrystals : Along the path to improved medicines
Active pharmaceutical ingredients (APIs) may exist in various solid forms, which can lead to differences in the intermolecular interactions, Differences in solid forms often lead to differences in thermodynamic parameters and physicochemical properties for example solubility {especially that a lot of drugs are in Class II and IV according to BCS (Biopharmaceutics Classification System) and these classes suffer from poor aqueous solubility and hence low bioavailability} ,dissolution rate, stability and mechanical properties of APIs and excipients. Hence, solid forms of APIs play a vital role in drug discovery and development.
Pharmaceutical chemistry: Drugs and their biological targets
Pharmaceutical chemistry (PC) represents a dynamic field of research that plays a pivotal role in the development of life-saving pharmaceuticals. PC is a precise science: One needs to rely on the accuracy of previous discoveries that have provided massive amount of precious information and databases as a solid foundation to move forward. PC is also an art where the artist uses a subtle mixture of knowledge, experimental learning, creativity, intuition, boldness, and serendipity to paint the right canvas. Nature often serves as a stimulus for pharmaceutical chemists. Many drugs are derived from natural compounds found in plants, fungi, or microorganisms. Chemists study these natural sources, seeking inspiration to design synthetic molecules that mimic the therapeutic properties of the originals while optimizing their characteristics. Francis Collins, geneticist and expert in the pharmaceutical industry, explains that the molecular cause of 4,000 diseases is no longer a secret to humanity, but there are only treatments available for 250 of them. Therefore, the world requires more professionals who can produce better medicines and solve more needs.
Pharmaceutical Analysis for Small Molecules
Designed to assist both recent graduates, as well as experienced chemists or scientists with limited regulatory, compendial or pharmaceutical analysis background, make that transition, Pharmaceutical Analysis for Small Molecules is a concise, yet comprehensive introduction to the drug development process and analysis of chemically synthesized, small molecule drugs. It features contributions by distinguished experts in the field, including editor and author, Dr. Behnam Davani, an analytical chemist with decades of technical management and teaching experience in compendial, regulatory, and industry.
Pertubation Compensator based Robust Tracking Control and State Estimation of Mechanical Systems
Investigates a practical way to achieve robust motion control and state estimation (Kalman filtering) of mechanical systems, which is a promising approach in terms of the perturbation compensator. The book presents novel approaches for design and analysis of perturbation observers as well as an extension to robust motion control and robust state estimation. The book is written in a self-contained manner including experimental results in each chapter clearly validating the developed theories.
Persuasive Technology ; 3rd International Conference, PERSUASIVE 2008, Oulu, Finland, June 4-6, 2008. Proceedings
Featuring full and short papers, posters and panels, Persuasive2008 highlighted new knowledge in the understanding and design of persuasive technology. The event brought together researchers, practitioners, and industry professionals - terested in this important new ?eld. Research themes of the conference included motivation altechnology, persuasivegames, smartenvironments, Web2.0, mobile persuasion, well-being and health behavior. In addition, attendees and part- ipants explored the theory and ethics of persuasive technology, social and - ganizational issues, business models for persuasive systems, and conceptual and theoretical approaches.
Persuasive Technology ; 2nd International Conference on Persuasive Technology, PERSUASIVE 2007, Palo Alto, CA, USA, April 26-27, 2007. Revised Selected Papers
Persuasive technology is the general class of technologies that purposefully apply psychological principles of persuasion – principles of credibility, trust, reciprocity, authority and the like – in interactive media, in the service of changing their users’ attitudes and behavior. Only one year ago, in 2006, the first international conference in this area, PERSUASIVE 2006 was hosted in Eindhoven.
Persuasive Technology ; 1st International Conference on Persuasive Technology for Human Well-Being, PERSUASIVE 2006, Eindhoven, The Netherlands, May 18-19, 2006, Proceedings
Persuasive technology is the general class of technology that has the explicit purpose of changing human attitudes and behaviours. Persuasive technologies apply principles of social psychology in influencing people; principles of credibility, trust, reciprocity, authority and the like. Social psychologists have spent a great deal of effort over many years in trying to understand how attitude and behaviour change comes about, focusing on the effectiveness of human persuaders, and the persuasive power of messages delivered through non-interactive mass-media, such as newspapers or television.
Perspectives on European Earthquake Engineering and Seismology ; Vol.2
The book’s nineteen state-of-the-art chapters were written by the most prominent researchers in Europe and address a comprehensive collection of topics on earthquake engineering, as well as interdisciplinary subjects such as engineering seismology and seismic risk assessment and management. Further topics include engineering seismology, geotechnical earthquake engineering, seismic performance of buildings, earthquake-resistant engineering structures, new techniques and technologies, and managing risk in seismic regions.
Perspectives on European Earthquake Engineering and Seismology ; Vol.1
Collects 5 keynote and 15 theme lectures presented at the 2nd European Conference on Earthquake Engineering and Seismology (2ECEES), held in Istanbul, Turkey, from August 24 to 29, 2014. The conference was organized by the Turkish Earthquake Foundation - Earthquake Engineering Committee and Prime Ministry, Disaster and Emergency Management Presidency under the auspices of the European Association for Earthquake Engineering (EAEE) and European Seismological Commission (ESC).
Perspectives of Neural-Symbolic Integration
This carefully edited volume contains state-of-the-art contributions in neural-symbolic integration, covering `loose' coupling by means of structure kernels or recursive models as well as `strong' coupling of logic and neural networks. It brings together a representative selection of results presented by some of the top researchers in the field, covering theoretical foundations, algorithmic design, and state-of-the-art applications in robotics and bioinformatics.
Perspective sketching : Freehand and digital drawing techniques for artists & designers
This book offers a command of the basic principles of perspective that is essential to creating dynamic, plausible compositions. With a user-friendly approach, this step-by-step guide will help you master the basics like scale drawing, contour line drawing, linear perspective, tone and texture, and more. Freehand skills like intuitive perspective and concept sketching help you to deepen your technique. Artist and designer Jorge Paricio also includes lessons on working with 3-D modeling in SketchUp and painting in Photoshop and provides a full chapter in blending traditional hand skills with digital media.
Personalized oral health care : From concept design to clinical practice
Provides an overview of the oral health care environment as the transition is made to a system increasingly focusing on disease prevention, early intervention to minimize disease progression, and a personalized approach that meets each individual’s needs.
Personal Wireless Communications ; IFIP TC6 11th International Conference, PWC 2006, Albacete, Spain, September 20-22, 2006, Proceedings
This book constitutes the refereed proceedings of the IFIP-TC6 11th International Conference on Personal Wireless Communications, PWC 2006. The book presents 25 revised full papers and 13 revised short papers, carefully reviewed and selected from 100 submissions. The papers are organized in topical sections on mobile and wireless networking, QoS, ad-hoc, security, wireless LAN, cross-layer design, wireless sensor networks, physical layer, and mobile and wireless applications.
Permutation, Parametric, and Bootstrap Tests of Hypotheses
This text will equip both practitioners and theorists with the necessary background in testing hypothesis and decision theory to enable innumerable practical applications of statistics. Its intuitive and informal style makes it suitable as a text for both students and researchers. It can serve as the basis a one- or two-semester graduate course as well as a standard handbook of statistical procedures for the practitioners’ desk. The revised and expanded text of the 3rd edition includes many more real-world illustrations from biology, business, clinical trials, economics, geology, law, medicine, social science and engineering along with twice the number of exercises. Real-world problems of missing and censored data, multiple comparisons, nonresponders, after-the-fact covariates, and outliers are dealt with at length. New sections are added on sequential analysis and multivariate analysis plus a chapter on the exact analysis of multi-factor designs based on the recently developed theory of synchronous permutations.
Peri-implant soft tissue management : A clinical guide
Provides dentists who place dental implants with a thorough overview of how to deal with the various challenges that they are likely to face in delivering appropriate soft tissue management. Various modalities and techniques for handling soft tissue during the surgical and restorative phases are clearly described, with discussion of different flap designs and the implications of the patient’s medical condition.
Performance-based seismic design of concrete structures and infrastructures
Provides contributions on Earthquake Engineering and on Performance-Based design of concrete structures. This book includes topics such as advanced methods for the seismic assessment and vulnerability of structures, strength-based and deformation-based design, and Numerical Models for the Seismic Assessment of Concrete Structures.
Performance Modeling and Engineering
This book presents the latest advances in methodology and techniques of performance modeling and engineering, ranging from theoretical advances to system and architecture developments, from technology to economics, from academic innovations to engineering processes, from statistical analysis to system control, and from enterprise systems to computer networks. The collection promotes innovative research in these emerging topics, bridging the gap between theory and practice, and stimulating the use of these new developments.
Performance Evaluation and Planning Methods for the Next Generation Internet
GERAD :The Center was created in 1980 by a small group of professors and researchers of HEC Montreal, GERAD's activities achieved sufficient scope to justify its conversion in June 1988 into a Joint Research Centre of HEC Montreal, the Ecole Polytechnique de Montreal and McGill University. In 1996, the U- versite du Quebec a Montreal joined these three institutions. GERAD has fifty members (professors), more than twenty research associates and post doctoral students and more than two hundreds master and Ph.D. students. GERAD is a multi-university center and a vital forum for the devel- ment of operations research. Its mission is defined around the following four complementarily objectives: • The original and expert contribution to all research fields in GERAD's area of expertise; • The dissemination of research results in the best scientific outlets as well as in the society in general; • The training of graduate students and post doctoral researchers; • The contribution to the economic community by solving important problems and providing transferable tools.The wide range of topics covered in this book is a witness to the diversity of problems that have to be faced if we want to design the Next Generation IP Networks to meet their expected performance. This is a rich field where optimization techniques can provide significant gains
Peptide therapeutics : Fundamentals of design, development, and delivery
Explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues. It covers the design concept of peptide therapeutics from fundamental principles using structural biology and computational approaches. A fresh graduate or a scientist who works on small molecules can use this to follow the design and development of peptide therapeutics to use as understanding the basic concepts. Each chapter is written by experts from academia as well as industry. The book provides concepts of design, synthesis, delivery, as well as regulatory affairs and manufacturing of peptides in a systematic way with examples in each case. The book can be used as a reference for a pharmaceutical or biomedical scientist or graduate student who wants to pursue their career in peptide therapeutics. Some chapters will be written as a combination of basic principles and protocol so that scientists can adopt these methods to their research work. The examples provided can be used to perform peptide formulation considerations for the designed peptides.
