الصفحة 64
الصفحة 64
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Heterogeneous Enantioselective Hydrogenation : Theory and Practice

The book looks at the first relatively ineffective catalysts right through to modern highly effective enantioselective catalytic systems, comparable in their efficiency to chiral metal complexes and enzymatic systems. The book begins with a summary of the first work on heterogeneous metal catalysts, which showed only the principal possibilities of enantioselective reactions. The book then elaborates on metal catalysts which have enantioselectivities close to 100%. Finally, the book describes the practical utilization of chiral catalytic systems in processes of hydrogenation. The a - and b -hydroxy carboxylic acid esters produced are precursors for manufacturing many synthones used for medicines as well as for monomers used for biodegradable polyesters, both of which have important practical applications. The book summarizes more than 800 scientific papers in the field of enantioselective catalytic hydrogenation reactions, mainly those using heterogeneous metal catalysts. It provides detailed explanations of special techniques for the preparation of effective dissymmetric catalysts which provide highly efficient catalytic systems.

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Hermann Cohens Critical Idealism

Publications on Cohen in the English language are small in number and this volume aims to fill the gap. It offers an analysis of Cohen’s System of Philosophy - the three-volume classic on logic, ethics, and aesthetics - and his writings on Judaism and religion. The book highlights Cohen’s contributions in these fields, including his discussions with Maimonides, Leibniz, Kant, and Hegel. It demonstrates the congeniality of Cohen’s critical idealism as expounded in the System and his writings on Judaism, and offers an overview of contemporary Cohen research.

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Herbs for stress & anxiety : How to make and use herbal remedies to strengthen the nervous system

Treat stress, anxiety, depression, and more with simple herbal remedies that calm your mind, build a healthy nervous system, and promote lasting peace. In this informative guide, renowned herbalist Rosemary Gladstar profiles 21 herbs proven to be effective at soothing common ailments like insomnia, panic attacks, skin conditions, and migraines. With simple directions for making herbal mixtures that can be used in delicious teas, tinctures, and capsules, Gladstar shows you how to harness the power of nature to achieve a more relaxed and fulfilling life.

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Herbal pharmacopeia : Nanotechnology and advancing drug

Explores the intersection between traditional herbal medicine and cutting-edge nanotechnology. The chapters introduce modern techniques used in herbal extraction and analysis. The principles of drug discovery from plants are discussed, with a focus on the identification and development of bioactive compounds that have therapeutic potential. It discusses the pharmacological properties, biotechnological approaches in drug development, and challenges in the formulation and standardization of herbal medicines. Emerging trends and applications of nanotechnology in herbal pharmacotherapy, such as nanoparticle synthesis, enhanced bioavailability using nanocarriers, safety assessments, novel and targeted delivery systems, and regulatory considerations, are thoroughly discussed. Additionally, it includes a comparative analysis of traditional and nano-formulated approaches and their implementation in clinical settings. Towards the end, the book reviews the regulatory considerations for herbal products and future perspectives in herbal pharmacopeia. This book is intended for researchers, clinicians, and professionals in herbal medicine, pharmacology, and nanotechnology.

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Herbal medicine in India : Indigenous knowledge, practice, innovation and its value

Covers Indian herbal medicines, health products, pharmaceuticals, nutraceuticals, and cosmetics. Highlights the status quo and future prospects of traditional medicine in India / Provides information on drug discovery, ethnobotany, isolation of phytochemicals, importance of herbal nutraceuticals, etc. / Covers innovation, validation and IPR issues related to Indian traditional medicine

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Herbal immunity boosters against COVID-19

Provides an introduction to COVID-19 and herbal medications that boost the human immune system against SARS-CoV-2. The topics are covered in 7 chapters starting with an introduction to the disease, followed by notes on nutraceuticals and common herbal medicines that have therapeutic potential by enhancing the patient’s immune response. Special topics such as COVID-19 risk factors and Indian traditional medicines are also included to supplement the contents. The editors have taken advantage of the vast body of knowledge accumulated since the start of the COVID-19 pandemic in 2019.

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Herbal bioactive-based drug delivery systems ; 1st ed.

Provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments.

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Hepatitis C virus-host interactions and therapeutics : Current insights and future perspectives

The burden of hepatitis C virus (HCV) infection on the public health care system continues to remain significant despite the remarkable progress made in HCV therapeutics in the recent past. There are now almost a dozen oral interferon-free direct-acting antivirals available for the treatment of hepatitis C virus infection. Despite advances in the treatment of HCV, therapeutic gaps remain that are yet to be fully explored. Researchers and scientists still strive to understand virus-host interactions to map the disease’s progression along with extrahepatic manifestations and virus invasion strategies impacting the host’s immune system. This book briefly discusses the biology of HCV infection, virus-host interactions, molecular epidemiology of the infection, and the full spectrum of immune responses to hepatitis C. It also provides in-depth information about HCV, clinical diagnostics, and therapeutic knowledge to all stakeholders involved in HCV screening, diagnosis, treatment, and management.

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Hemodynamical Flows : Modeling, Analysis and Simulation

This book surveys research results on the physical and mathematical modeling, as well as the numerical simulation of complex fluid and structural mechanical processes occurring in the human blood circulation system. Topics treated include continuum mechanical description; choice of suitable liquid and wall models; mathematical analysis of coupled models; numerical methods for flow simulation; parameter identification and model calibration; fluid-solid interaction; mathematical analysis of piping systems; particle transport in channels and pipes; artificial boundary conditions, and many more.

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Hematopoietic Stem Cell Transplantation

Stem Cell Transplantation for Hematologic and Other Disorders, Second Edition provides a glimpse into potential future applications of bone marrow derived stem cells in the field of cardiac repair.

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Hematologic Malignancies : Acute Leukemias

Several chapters in this volume describe current knowledge of acute leukemia biology and discuss new classification systems that have arisen consequent to emerging insights into pathogenesis. Treatment has also improved for particular types of acute leukemia.

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Hedgehog-Gli Signaling in Human Disease

Hedgehog-GLI Signaling in Human Disease represents the first compilation of up-to-date reviews by top-level scientists in this important field of research. The chapters cover a wide spectrum of related interests, from the molecular bases of morphogen function, to human genetics to cancer research. The aim of the book is to disseminate information on this exciting field, to allow students, scientists and the public in general to gain access current information from research leaders and to provide a book that encompasses different aspects of research showing the fusion of basic research in model systems and medicine. This is a timely primer on how a system of cell communication, Hedgehog-GLI signaling, plays a critical role in human disease and thus provides the background for the development of novel and rational therapies.

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Heavy-Tail Phenomena : Probabilistic and Statistical Modeling

This comprehensive text gives an interesting and useful blend of the mathematical, probabilistic and statistical tools used in heavy-tail analysis. Heavy tails are characteristic of phenomena where there is a significant probability of a single huge value impacting system behavior. Record-breaking insurance losses, financial returns, sizes of files stored on a server, transmission rates of files are all examples of heavy-tailed phenomena.

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Heating, cooling, lighting : Sustainable design methods for architects

Helps architects minimize mechanical systems and energy usage over the life of the building by siting, building design, and landscaping to maximize natural heating, cooling, and lighting. This new fourth edition includes new information on integrated design strategies and designing for the Tropics. Resources include helpful case studies, checklists, diagrams, and a companion website featuring additional cases, an image bank, and instructor materials. Designing buildings that require less energy to heat, cool, and light means allowing the natural energy of the sun and wind to reduce the burden on the mechanical and electrical systems. Basic design decisions regarding size, orientation, and form have a great impact on the sustainability, cost, and comfort of a building. Heating, Cooling, and Lighting provides detailed guidance for each phase of a design project.

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Heat Shock Proteins and the Brain : Implications for Neurodegenerative Diseases and Neuroprotection

Neurodegenerative disorders such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease and amyotrophic lateral sclerosis have been termed ‘protein misfolding disorders’ that are char- terized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a the- peutic strategy to counter conformational changes in neural proteins that trigger pathogenic cascades resulting in neurodegenerative diseases. Heat shock proteins are protein repair agents that provide a line of defense against misfolded, aggregati- prone proteins. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection reviews current progress on neural heat shock proteins (HSP) in relation to neurodegenerative diseases (Part I), neuroprotection (Part II), ext- cellular HSP (Part III) and aging and control of life span (Part IV).

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Heat shock proteins : Potent mediators of inflammation and immunity

Written by leaders in the field of heat shock protein immunobiology, the chapters systematically and in a step wise fashion takes the reader through the fascinating sequence of events by which heat shock proteins activate immune responses and provides answers as to its biological significance to the host.

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Heat and Mass Transfer

This comprehensive textbook provides readers with a firm foundation in the principles of heat and mass transfer and shows them how to solve problems by applying modern methods. The basic theory is developed systematically, and the solution methods to all important problems are covered in detail. The second edition incorporates state-of-the-art findings on heat and mass transfer correlations. Therefore, this book will be useful not only to upper- and graduate-level students, but also to practicing scientists and engineers. Many worked-out examples and numerous exercises with their solutions will facilitate learning and understanding, and an appendix includes data on key properties of important substances.

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Hearing and Sound Communication in Amphibians

Hearing and Sound Communication in Amphibians is a compendium of the latest research on acoustic communication in these highly vocal vertebrates. The chapters are written by experts currently investigating the physiology and behavior of amphibians both in the laboratory and in the field. This integrated approach guides each chapter and provides a neuroethologically-driven and evolutionary basis for our understanding of acoustic communication and its underlying mechanisms. The intended audience ranges from senior undergraduates to physiologists, zoologists, evolutionary biologists and communication specialists.

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Healthcare, Frugal Innovation, and Professional Voluntarism : A Cost-Benefit Analysis

This book investigates what international placements of healthcare employees in low resource settings add to the UK workforce and the efficacy of the its national health system. The authors present empirical data collected from a volunteer deployment project in Uganda focused on reducing maternal and new-born mortality and discuss the learning and experiential outcomes for UK health care professionals acting as long term volunteers in low resource settings. They also develop a model for structured placement that offers optimal learning and experiential outcomes and minimizes risk, while shedding new light on the role that international placements play as part of continuing professional development both in the UK and in other sending countries.

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Health research in developing countries : A collaboration between Burkina Faso and Germany

Health research in developing countries has many facets. On one side, malaria and AIDS as main causes of morbidity and mortality are a focus for clinical and epidemiological studies. On the other side, the need for improving the health care system in general cannot be overestimated. The book offers a survey of current and important topics of health research in developing countries. Special emphasis is placed to show that cooperation of different health research areas if of highest importance in future. In addition the CRSN (Burkina Faso) - University of Heidelberg collaboration is given as a model that allows high class research in remote areas of any developing country. An absolutely must for all who are working in clinical, epidemiological and health systems research for and in developing countries.

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