الصفحة 6
الصفحة 6
Imaging nelle urgenze vascolari - Body : Casi clinici = Imaging in vascular emergencies - Body : Clinical cases
Vascular urgency is true urgency. Given the variability of clinical presentations, the radiologist is increasingly called into question for diagnostic-differential problems and he is entrusted with the nosological framework and the therapeutic choices of doubtful cases. The purpose of the book is to provide, through the presentation of a large number of cases, an easy, fast and stimulating means through which the reader can confront.
Ileo meccanico dell’intestino tenue : Aspetti TC e correlazioni eco-radiografiche = Mechanical ileus of the small intestine : CT aspects and echo-radiographic correlations
Mechanical occlusion of the small intestine is a frequently encountered clinical problem, whose clinical-instrumental management is made difficult by the complexity of the mechanisms responsible for the occlusive picture. The role of the radiologist is to promptly guide the therapeutic process on the basis of a correct interpretation of the iconographic pictures. The purpose of this volume - the only one of its kind - is to relate the pathophysiology of occlusion to imaging. The rich iconography, which ranges from clinical onset to resolution, emphasizes the role of multidetector computed tomography with intravenous contrast, which is the current gold standard. However, the correlations with the echo-radiographic methods are not forgotten, which retain an effective diagnostic role, with a low biological and economic cost. The mechanical ileus of the small intestine is a striking example in support of the dream of many professionals: that, that is, to have a figure of a fine abdominal emergency radiologist, an expert in organ and disease and not only in the machine, as often unfortunately it happens.
Il metodo clinico rivisitato : Lezioni e seminari di clinica medica = The Clinical Method Revisited : Clinical Medical Lectures and Seminars
This volume, dedicated to medical students who live the exciting moment of initiation into the medical profession, is structured in eleven didactic modules, which are developed according to the typical sequence of problem solving revised in the light of the EBM method (presentation of problem, formulation and testing of hypotheses, formulation of clinical and background questions, comparison with international literature, answer to questions, application to the clinical case and possible formulation of recommendations for practice, case management). Linked to them are eight in-depth analyzes structured as compendia of evidence (Evidence compendia, in the style of Clinical Evidence), in which a series of background questions relating to complex pathologies, of high prevalence and of considerable interest for the hospital internist and of the territory. Although fundamentally designed for teaching, the book can also be a useful tool for all those who practice medicine by placing the man with his disease at the center of the diagnostic-therapeutic procedure.
Ibuprofen : Pharmacology, Therapeutics and Side Effects
Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions. Over the past 40 years, ibuprofen has been proven to be as safe or even safer and also as effective as the established non-steroidal anti-inflammatory drugs (NSAIDs) and the coxibs. This well-written book reviews the pharmacology, clinical uses and the various adverse effects of Ibuprofen, the disposition and unique modes of action in relation to clinical effects of the drug as well as various formulations. The use of combinations with other drugs (e.g. paracetamol, codeine, caffeine) are critically assessed and the impact of natural products and Chinese Medicines on the safety of ibuprofen.
Ibuprofen : Discovery, development and therapeutics
Ibuprofen has become one of the foremost pain-relieving medications world-wide with its proven safety and efficacy in a wide variety of painful and inflammatory conditions. It has also been widely investigated for application in a variety of painful and non-pain inflammatory states including cancer and neurodegenerative conditions, reflecting the unique and novel properties of the drug that would never have been foreseen from knowledge of the properties when it was initially discovered.
Ibuprofen : Clinical Pharmacology, Medical Uses and Adverse Effects
Presents topical research in the study of the clinical pharmacology, medical uses, and adverse effects of ibuprofen. Topics discussed include the occurrence, ecotoxicity and water remediation technologies of ibuprofen in the aquatic environment; associated adverse drug reaction in ibuprofen use; hybrid multifunctional ibuprofen drugs; a pharmaceutical nanotechnology approach to ibuprofen delivery; vibrational dynamics and chiral properties of racemate and pure enantiomers of ibuprofen complexed in cyclodextrins; therapeutic effects of ibuprofen on transgenic mice models of neurodegenerative diseases; and the use of ibuprofen for pain relief in gynecology.
I recettori dellangiotensina : Dalla biologia molecolare alla terapia con gli antagonisti recettoriali
Describes all the structural and functional characteristics of angiotensin receptors, with particular reference to their molecular and pharmacological properties. The therapeutic applications of AT1 receptor antagonists and the results obtained from large trials are also discussed, especially in arterial hypertension, heart failure, diabetic nephropathy and stroke.
Hypertension in the Elderly
Topics range from basic concepts, epidemiology and trials, and evaluation and management, to pharmacological treatment, special populations, and adherence, all presented with an emphasis on the optimal management of patients. The authors examine in detail the mechanisms of hypertension in the elderly, particularly age-related changes in vascular stiffness, and methodically review the lifestyle and outcomes trials that were conducted in older persons. The problems of clinical evaluation, secondary hypertension, and target organ damage are also fully addressed, and a practical approach is provided for correctly determining blood pressure, one of the most important tasks in evaluating an older patient. Extensive discussions of pharmacological therapy detail the role of individual drug classes, including diuretics and b-blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, calcium antagonists, a-1 blockers, and combination drug therapies. Additional chapters focus on special populations, such as African Americans, patients with diabetes, and patients with arthritis, as well as on the clinician's role in improving therapeutic adherence in older patients. Offers family practitioners and general internists an up-to-date, user-friendly reference on the diagnosis, treatment, and complications of hypertension in the elderly.
Hyperlipidemia Management for Primary Care : An Evidence-Based Approach
Hyperlipidemia Management for Primary Care: An Evidence-Based Approach is a comprehensive resource for primary care providers that offers information and treatment options that can be incorporated with ease into everyday clinical practice. This evidence-based text weighs the benefits of pharmacologic treatments, popular diets, therapeutic foods, herbs and vitamins as a means to manage hyperlipidemia.
Hydrogels : Design, Synthesis and Application in Drug Delivery and Regenerative Medicine
Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions.
Human Nucleotide Expansion Disorders
Human neurological and neuromuscular disorders caused by nucleotide expansion, first discovered in 1991, are the focus of growing interest of practicing physicians and of interested biomedical researchers. This volume represents a comprehensive and up-to-date description of many of the better-studied disorders. The expert authors discuss molecular, clinical and pathological aspects of the diseases as well as our current understanding of their underlying mechanisms. Of special interest are ideas and initial results of the different therapeutic strategies that can be employed to overcome some of the disorders. As a summary of the state-of-the-art research in this field, this book is of value to human geneticists, molecular biologists and biochemists as well as to practicing neurologists and pediatricians.
Human microbiome : Clinical implications and therapeutic interventions
The human microbiome refers to the complete microorganisms inhabiting the human body sites including skin, ear, nose, oral cavity, the genital, gastrointestinal and respiratory tracts, and body fluids such as breast milk, saliva, and urine. It is a significant and essential organ recognized for the body and has an established involvement in the host wellbeing, in terms of nutritional requirements and immunomodulation. Talks about how alteration and imbalance in the same can have clinical implications associated with a multitude of gastrointestinal, lifestyle-associated, and neurodegenerative disorders. How the proliferation of specific groups of bacteria and their metabolic activities, as a result of intestinal dysbiosis leads to the 'leaky gut' condition thereby influences brain activity via the bidirectional gut-brain axis. It also coves the importance of microbial seeding and how it can be influenced by the mode of delivery, nutrition, and medication. This book also provides various therapeutic interventions such as the establishment of stool banks and Faecal microbiota transplantation (FMT) that have recently proved promising in the treatment of ASD, Inflammatory Bowel Disease, and Ulcerative Colitis. This book provides a deeper understanding of the development of the human gut microbiome and the factors driving its dysbiosis. This book is a valuable read for health professionals, medical students, nutritionists, and scientific research communities who are eager to update themselves with recent trends in microbiome research. It will also aid gastroenterologists and nutritionists to make well-informed choices regarding therapeutic regimes.
Human fungal diseases : Diagnostics, pathogenesis, drug resistance and therapeutics
Reviews the latest advancements in the fungal infections and their impact on human health. It presents epidemiology, diagnosis, pathogenesis, risk factors, virulence mechanisms, treatment, and strategies for the disease management and prevention of fungal infections. The book further reviews host-pathogen interactions, biofilm formation, and quorum sensing. It also covers the clinical manifestations, diagnostic approaches, and management strategies of opportunistic fungal infections, emerging fungal infections, and allergic fungal infections. It presents the latest advancements in diagnostic methods and therapeutic strategies, covering both conventional techniques and state-of-the-art approaches. Further, the book elucidates antifungal stewardship, nanotechnology, and omics technologies, providing insights into cutting-edge strategies for prevention, control, and management of multidrug-resistant fungi. This book is useful for researchers, students, and health professionals working in the fields of mycology, infectious diseases, immunology, dermatology, and pulmonology.
Human antibody therapeutics for viral disease
The articles in this volume are definitive and comprehensive reviews written by experts who have sought to define the principles of viral neutralization by human antibodies. They explore and anticipate the obstacles and opportunities that will be encountered as the power of human antibodies is harnessed to address the vast, un-met need for effective anti-viral therapeutics.
Hugo and Russell's pharmaceutical microbiology
Microbiology is one of the essential pharmaceutical sciences upon which the study and practice of pharmacy is built. It has a bearing on all aspects of the manufacture of medicines and sterile products, from their design and development to their delivery as quality products. Few interventions are more central to modern medicine than the treatment of infection, where antibiosis, vaccination and hygienic practices have essential roles to play. The COVID-19 pandemic, the appearance of new pathogens and the rise of antibiotic resistance have demonstrated most completely the need for pharmaceutical practitioners, researchers and industrial scientists to be fully conversant with this field. The 9th edition of Hugo and Russell’s Pharmaceutical Microbiology has been updated to meet this need. Having long served as the sole comprehensive textbook covering this subject, it has now been adapted to a critical new period in the advancement of medical and pharmaceutical research and development. Its experienced editors have incorporated contributions from subject experts and created a text which will serve the next generation of pharmacy students, pharmaceutical industry scientists and researchers.
Hormones, metabolism and the benefits of exercise
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Honey and olive oil in diabetic foot therapy
At the beginning of the 21st Century diabetic foot is Observed, although eminently preventable, represent one of the commonest causes of hospital inpatient in Western countries. Diabetic foot is a pathological condition that might affect the feet in patients with diabetes. Foot ulcers are defined as lesions involving a skin break with loss of epithelium: they can extend into the dermis and deeper layers sometimes involving bone and muscle...
Honey : Nutraceutical and therapeutic significance
Contains comprehensive information on honey with regard to its cosmeceutical, nutritional, and pharmacological significance. And providing enormous knowledge about the nutraceutical and the role of different therapeutic strategies across the globe. Each chapter has the latest references and citations so that readers may get the latest knowledge in the field.
High-Grade Gliomas : Diagnosis and Treatment
This is truly an exciting time in the field of neuro-oncology, particularly in the area of hi- grade gliomas. The management of patients with high-grade gliomas has historically been one of the most challenging and disheartening fields in medicine, where failure is the rule and longevity is the exception. The jaded often state that despite purported advances in surgical and radiotherapeutic techniques and a myriad of clinical trials of medical therapies, the s- vival statistics for glioblastoma have not changed in the last three decades. The nihilism associated with these tumors is such that some practitioners still advise against treatment or even biopsy, recommending palliative care with the diagnosis based only on history and an MRI scan. If the current state-of-the-art in the diagnosis and management of high-grade gliomas was truly so bleak, there would be no reason to compile and publish a monograph on the subject. The fact is that we have recently entered an era where real progress is being made in our understanding and treatment of high-grade gliomas that is directly benefiting some patients. We are slowly but surely chipping away at this problem. One approach has exploited correlations between particular molecular markers and therapeutic response.
High dilution effects : Physical and biochemical basis
this volume provides evidence in support of effects from control clinical studies, and in vitro tests without any organisms (Chapter II). An overview of the methods for preparing drugs at ultra high dilution is also provided as well as the basic principles of homeopathy, (Chapter I). Chapter III provides physical basis of high dilutions as evidence from the NMR, IR, UV and fluorescence spectra of those drugs.Chapter IV focuses on the mechanism of action of potentized drugs in the living system, discussing the structure of the cell, the plasma membrane, the integral proteins on the membrane, the interaction between these proteins and high dilutions and the manifestations of the therapeutic effects of high dilutions.
