الصفحة 6
الصفحة 6
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Cell Adhesion and Cytoskeletal Molecules in Metastasis

In this volume, the expression of specific adhesion molecules within human cancer tissues are highlighted. The expression signatures from published DNA microarray and immunohistochemistry studies are detailed. The concept that the alteration of specific adhesion molecules influence the cancer migration ability and cancer damage responses is detailed in this volume; both features are essential for the survival of an invading tumor cell. Defining the minimal adhesion receptors preserved on cancer cells during tumor progression will define the metastatic adhesion signature. Understanding the metastatic adhesion signature will reveal vulnerabilities that could be exploited for the prevention and/or eradication of the invading cancer cell.

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Cancer in the Spine : Comprehensive Care

In Cancer in the Spine: Comprehensive Care, distinguished physicians and researchers from prestigious cancer centers around the world critically examine current trends and innovations in spinal cancer management. Detailing both the fundamental principles of diagnosis and treatment planning, and the cutting-edge techniques of tumor treatment, these experts bring together in one volume a guide to coordinated management of all aspects of cancer in the spine.

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Cancer and Pregnancy

This book is written by experts with clinical expertise on diagnosis, treatment, and follow-up of women with cancer during pregnancy. It provides a comprehensive review of data and an overview of psychological, ethical, and social aspects.

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Broadband Opto-Electrical Receivers in Standard CMOS

Broadband Opto-Electrical Receivers in Standard CMOS starts from the basic fundamentals, necessary for the design of opto-electronic interface circuits. The book continues with an in-depth analysis of the photodiode, transimpedance amplifier (TIA) and limiting amplifier (LA). To thoroughly understand the light detection mechanisms in silicon, first a one-dimensional and second a two-dimensional model is developed. Analytical design equations are derived to guide the design of the amplifying circuits. For the TIA, the focus lies on the sensitivity-speed trade-off. For the LA, a high gain-bandwidth is pursued. Several practical design examples reveal the subtleties and challenges encountered during the design of high-performance analog circuits.

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Bridge Launching

It is devoted to bridges that are built by incremental launching methods, using prestressed composite materials. It integrates the static, aesthetic, and economic aspects of construction techniques for building these state-of-the-art structures. Bridge launching is a comprehensive handbook, offering explanations of both the theoretical and technological aspects of the construction process. Both beam bridges and arch bridges are thoroughly analysed,and special theories aimed at optimising static aspects, as well as local phenomena, are developed.

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Breast cancer genetics, immunology, and immunotherapy : An interdisciplinary approach

Publishes comprehensive volumes on immune and genetic mechanisms of breast cancer diagnosis and prognosis. The role of molecular genetics, interleukins, chemokine receptor, and tumor-infiltrated lymphocytes-TILS in breast cancer are explained. Targeting myeloid determinants, SiRNA loaded in drug delivery nanosystems, nucleic acid and drug dual agent nanoplatforms, and oncolytic virotherapy are also discussed in the treatment of breast cancer, particularly in multidrug resistant and metastatic breast cancer.

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Biophysical characterization of functional peptides

Presents reproducible and step-by-step procedures for the peptide synthesis, their characterization and applications. The volume includes an introductory section on in silico modelling of new peptide molecules, Molecular Dynamics Simulations, Docking, Electrostatic fingerprinting of peptides, and other modelling tools for peptide designing and optimization. Further, it covers protocols for the solid phase peptide synthesis, chromatographic and mass spectrometric characterization of peptides. Importantly, it covers methods for biophysical characterizations of peptides for their potential applications as drug delivery vehicles, peptide nano-assembly, bionanocatalysis, protein aggregation diseases, and peptide-based anti-bacterial.

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BioMEMS

Here, a new discipline evolved which focuses on microsystems for living systems called "BIOMEMS". In this review at a glance the exciting field of bio-microsystems, from their beginnings to indicators of future successes are presented. It will also show that a broad penetration of micro and nano technologies into biology and medicine will be mandatory for future scientific and new product development progress in life science.

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Bernoulli potential in superconductors : How the electrostatic field helps to understand superconductivity

The motion of electrons in superconductors seems to defy our imagination based on daily experience with Newtonian mechanics. This book shows that the classical concepts, such as the balance of forces acting on electrons, are useful for understanding superconductivity. The electrostatic field plays a natural part in this balance as it mediates forces between electrons at long distances. Due to its classical interpretation, the theory presented in this book is suitable for introductory courses.

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Basic theoretical physics : A concise overview

This concise treatment embraces, in four parts, all the main aspects of theoretical physics (I . Mechanics and Basic Relativity, II. Electrodynamics and Aspects of Optics, III. Non-relativistic Quantum Mechanics, IV. Thermodynamics and Statistical Physics). It summarizes the material that every graduate student, physicist working in industry, or physics teacher should master during his or her degree course. It thus serves both as an excellent revision and preparation tool, and as a convenient reference source, covering the whole of theoretical physics. It may also be successfully employed to deepen its readers' insight and add new dimensions to their understanding of these fundamental concepts. Recent topics such as holography and quantum cryptography are included, thus making this a unique contribution to the learning material for theoretical physics.

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Basic Electromagnetism and Materials

This textbook can be used to teach electromagnetism to a wide range of undergraduate science majors in physics, electrical engineering or materials science. However, by making lesser demands on mathematical knowledge than competing texts, and by emphasizing electromagnetic properties of materials and their applications, this textbook is uniquely suited to students of materials science. Many competing texts focus on the study of propagation waves either in the microwave or optical domain, whereas Basic Electromagnetism and Materials covers the entire electromagnetic domain and the physical response of materials to these waves.

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Atlas of clinical hematology

The volume covers all the microscopic methods in hematology that form the basis of diagnosis as well as the results of modern immunologic, cytogenetic and molecular-genetic investigation. Special emphasis is placed on the cytogenetic and molecular-genetic characterization of biological entities that might form the basis for innovative therapies.

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Architecting Systems with Trustworthy Components ; International Seminar, Dagstuhl Castle, Germany, December 12-17, 2004. Revised Selected Papers

This book constitutes the thoroughly refereed post-proceedings of the International Dagstuhl-Seminar on Architecting Systems with Trustworthy Components, held in Dagstuhl Castle, Germany, in December 2004. The 10 revised full papers presented together with 5 invited papers contributed by outstanding researchers were carefully selected and included in the book reflecting ongoing impovement from the seminar. Core problems addressed by the seminar are measurement and normalization of non-functional properties, modular reasoning over non-functional properties, capture of component requirements in interfaces and protocols, interference and synergy of top-down and bottom-up aspects, duality of componentization and architecture, system properties, and opportunities for correctness by construction/static checking.

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Applied scanning probe methodsVII : Biomimetics and industrial applications

The present volumes cover three main areas: novel probes and techniques (Vol. V), charactarization (Vol. VI), and biomimetics and industrial applications (Vol. VII). Volume V includes an overview of probe and sensor technologies including integrated cantilever concepts, electrostatic microscanners, low-noise methods and improved dynamic force microscopy techniques, high-resonance dynamic force - croscopy and the torsional resonance method, modelling of tip cantilever systems, scanning probe methods, approaches for elasticity and adhesion measurements on the nanometer scale as well as optical applications of scanning probe techniques based on near?eld Raman spectroscopy and imaging.

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Applied scanning probe methods IV : Industrial applications

The sc- ning probes emerged as a new - strument for imaging with a p- cision suf?cient to delineate single atoms. At first there were two – the Scanning Tunneling Microscope, or STM, and the Atomic Force Mic- scope, or AFM. The STM relies on electrons tunneling between tip and sample whereas the AFM depends on the force acting on the tip when it was placed near the sample. These were quickly followed by the M- netic Force Microscope, MFM, and the Electrostatic Force Microscope, EFM. The MFM will image a single magnetic bit with features as small as 10nm. With the EFM one can monitor the charge of a single electron.

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Applied scanning probe methods III : Characterization

The sc- ning probes emerged as a new - strument for imaging with a p- cision suf?cient to delineate single atoms. At first there were two – the Scanning Tunneling Microscope, or STM, and the Atomic Force Mic- scope, or AFM. The STM relies on electrons tunneling between tip and sample whereas the AFM depends on the force acting on the tip when it was placed near the sample. These were quickly followed by the M- netic Force Microscope, MFM, and the Electrostatic Force Microscope, EFM. The MFM will image a single magnetic bit with features as small as 10nm. With the EFM one can monitor the charge of a single electron.

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Applied scanning probe methods II : Scanning probe microscopy techniques

The sc- ning probes emerged as a new - strument for imaging with a p- cision suf?cient to delineate single atoms. At first there were two – the Scanning Tunneling Microscope, or STM, and the Atomic Force Mic- scope, or AFM. The STM relies on electrons tunneling between tip and sample whereas the AFM depends on the force acting on the tip when it was placed near the sample. These were quickly followed by the M- netic Force Microscope, MFM, and the Electrostatic Force Microscope, EFM. The MFM will image a single magnetic bit with features as small as 10nm. With the EFM one can monitor the charge of a single electron.

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Applied Charged Particle Optics

Authored by a pioneer of the field, this overview of charged particle optics provides a solid introduction to the field for all physicists wishing to design their own apparatus or better understand the instruments with which they work. Applied Charged Particle Optics begins by introducing electrostatic lenses and fields used for acceleration, focussing and deflection of ions or electrons. Subsequent chapters give detailed descriptions of electrostatic deflection elements, uniform and non-uniform magnetic sector fields, image aberrations, and, finally, fringe field confinement. A chapter on applications is added.

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Analog integrated circuits for communication : principles, simulation and design

This book covers the analysis and design of nonlinear analog integrated circuits that form the basis of present-day communication systems. Both bipolar and MOS transistor circuits are analyzed and several numerical examples are used to illustrate the analysis and design techniques developed in this book.

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Analog Design Essentials

The book starts with elementary stages in building up operational amplifiers. The synthesis of opamps is covered in great detail, such that lowest power consumption is always guaranteed. Many examples are included, operating at low supply voltages. Chapters on noise, distortion, filters, ADC/DACs and oscillators follow. These are all based on the extensive amount of teaching that the author has carried out both at universities and companies world-wide. All chapters have been drawn up specifically for self-study. They aim, however, at different levels of understanding. All start with elementary material. Most chapters also contain advanced material, especially from Chapter 9 onwards.

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