الصفحة 6
الصفحة 6
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Group interventions in schools : Promoting mental health for at-risk children and youth

Children who are labeled at-risk often suffer from severe deficiencies in cognitive, affective, and behavioral skills that, if unaddressed, may lead to limited prospects for future success and well-being. Tapping into the therapeutic potential of groups, this volume presents the theory and practice of cognitive-oriented group-centered counseling – combining intrinsic motivation, efficacy retraining, and targeted play therapy and social role-playing – that can be implemented to help children build core social skills and emotional regulation to complement their classroom instruction.

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Greening the Supply Chain

Since the Rio summit in 1992, the paradigm of corporate environmental responsibility has gradually and consistently extended beyond complying with increasingly stringent environmental regulation and taking up the proactive initiatives of a few world-class companies. Research indicates that the business and financial performance of companies may depend directly on socially and environmentally responsible business practices. Many world-class companies now realize that customers and other stakeholders do not distinguish between a company and its suppliers. As a result, greening the supply chain is an innovative idea which is fast gaining attention in the industry.

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Governance of Communication Networks : Connecting Societies and Markets with IT

The articles collected in this book shed light on several aspects that are crucial for the success of global communication networks: they range from an appropriate framework for regulation and suitable strategies of firms that act as international players, to the inclusion of customers in defining product and service strategies, and from problems of access to advanced technology and networks for all groups in society regardless of their social status or geographical location to the role of new technologies in facilitating universal communication.

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Governance of Arctic Shipping : Rethinking Risk, Human Impacts and Regulation

This is a result of the Dalhousie-led research project Safe Navigation and Environment Protection, supported by a grant from the Ocean Frontier Institute’s the Canada First Research Excellent Fund (CFREF).

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Good pharmacovigilance practice (GVP) : Focus on risk mangement plan (RMP)

Pharmacovigilance which is the science and activities relating to the detection, assessment, understanding and prevention of adverse drug reactions or any other possible drug related problems and Risk Management Strategies which provides a structured and coherent approach to identifying, assessing and managing risk and builds in a process for regularly updating and reviewing the assessment based on new developments or actions taken, conference provides the foundation for strong strategic planning and practical decision-making in pharmacovigilance programs. Stakeholders from medicines research, global regulation, and healthcare will join together to analyse the challenges for safety and pharmacovigilance efforts in this uncertain environment and examine effective strategies for addressing gaps and needs.

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Good laboratory practice for nonclinical studies

The GLP regulations have been enacted since 1978 and are currently under a proposed FDA amendment to revise terminology and accommodate other changes relating to advances in technology related to the industry. This book provides a unique opportunity to access interpretation of the 21CFR58 regulatory requirements from leading industry experts with a vast knowledge and expertise in their fields. The approach used takes the regulations, provides interpretations and references to examples and regulatory actions. Data integrity and the use of electronic systems in compliance with 21CFR11 Electronic Records: Electronic Signatures are also discussed.

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Good laboratory practice : The why and the how

The GLP regulations have developed from rules on how to exactly document the planning, conduct and reporting of toxicity studies to a quality system for the management of a multitude of study types, from the simple determination of a physical/chemical parameter to the most complex field studies or ecotoxicology studies. At the same time the term “Good Laboratory Practice” has become somewhat of a slogan with the aim to characterise any reliably conducted laboratory work.

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Golden gate cloning : Methods and protocols

Provides an overview of the latest protocols that cover the full range of in silico, in vitro, and in vivo approaches to help researchers plan, design, and perform Golden Gate cloning experiments. The chapters in this book cover topics such as Golden Gate cloning of standardized parts; modular DNA construct design for high-throughput Golden Gate Assembly; Golden Gate cloning of Synthetic CRISPR RNA spacer sequences; Golden Gate cloning in Actinobacteria; and YeastFab cloning of toxic genes and protein expression optimization in yeast.

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Global regulations of medicinal, pharmaceutical, and food products

Medicine regulation demands the application of sound medical, scientific, and technical knowledge and skills, and operates within a legal framework. Regulatory functions involve interactions with various stakeholders (e.g., manufacturers, traders, consumers, health professionals, researchers, and governments) whose economic, social, and political motives may differ, making implementation of regulation both politically and technically challenging. This book discusses regulatory landscape globally and the current global regulatory scenario of medicinal products and food products comprehensively.

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Global Product : Strategy, Product Lifecycle Management and the Billion Customer Question

In the early years of the 21st Century, as a result of many changes, it has become possible for the first time for tens of thousands of companies to offer manufactured products to customers across six continents. For many of these "global products", there are potentially more than a billion customers. In 2007, Wall Street hit new highs as the enormous opportunity for increased sales and profits became clear. However the new environment is not easy to manage and the risks are high. Meeting the various requirements of customers from a range of countries, choosing the most suitable locations for the different stages of development and manufacturing, deciding what can be global and what must be local, implementing suitable processes and systems, accommodating different national regulations, and efficiently dividing the workload between diverse sites are among the many challenges faced by providers of global products.

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Global perspectives on AI, ethics, and business economics : Charting the future

Offers an in-depth exploration of the complex and rapidly evolving world of artificial intelligence (AI), focusing on its ethical, economic, and business dimensions. it provides a comprehensive analysis that intertwines historical context, philosophical ethics, global economic impacts, regulatory landscapes, workforce dynamics, corporate governance, consumer behavior, data ethics, and the use of AI for the good of society. after reviewing the evolution of AI, it offers insights into its historical milestones and the trajectory it may take in the future. this sets the stage for a broader discussion on how AI is not just a technological phenomenon but also a catalyst for ethical, economic, and societal transformation. the book emphasizes the importance of understanding AI’s historical development in order to gauge its potential impacts on our future.

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Glass in Building : Principles, Applications, Examples

Offers a clear, compact, and illustrated overview of the material-appropriate use of this varied and versatile material in building construction and provides information that goes far beyond the basics on designing with glass and producing and using specialized glass products, as well as on the building and planning regulations that must be taken into account when constructing with glass. A selection of exemplary realized projects rounds out the theoretical section.

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Giving Death a Helping Hand : Physician-Assisted Suicide and Public Policy. An International Perspective

The volume focuses on public policy issues related to physician-assisted suicide. It offers a detailed analysis of the current legal standing and practice of physician-assisted suicide in various countries and discusses the ethical principles underlying its legal and professional regulation.

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GI Microbiota and Regulation of the Immune System

This book opens with two general reference chapters, which provide an over-view of current knowledge of gastrointestinal immunology and the commensal microbiology of the gut. Next are two chapters dedicated to current methodologies used to investigate the icrobiota and host: molecular analysis of microbial diver-sity and gnotobiotic research. Both positive and negative interactions between the microbiota and the immune system can take place in the gut, with chapters dedicated to probiotics and intestinal diseases associated with unhealthy rnicrobiota.

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Genome Mapping and Genomics in Arthropods

Mapping of animal genomes has generated huge databases and several new concepts and strategies, which are useful to elucidate origin, evolution and phylogeny. Genetic and physical maps of genomes further provide precise details on chromosomal location, function, expression and regulation of academically and economically important genes. The series "Genome Mapping and Genomics in Animals" provides comprehensive and up-to-date reviews on genomic research on a large variety of selected animal systems, contributed by leading scientists from around the world.Insects and other arthropods, the largest group of animals in number of species, have global impact on agriculture, industry, human health and environment. They are of particular economic importance for food production as pollinators, for natural products like silk and also as pests and parasites. Arthropods covered in this volume include honeybee, bumblebee, the parasitic Jewel Wasp, silkworm, pea aphid, mosquito, Hessian fly and tick.

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Genome instability in cancer development

Research over the past decades has firmly established the genetic basis of cancer. In particular, studies on animal tumour viruses and chromosome rearrangements in human tumours have concurred to identify so-called ‘proto-oncogenes’ and ‘tumour suppressor genes’, whose deregulation promotes carcinogenesis. These important findings not only explain the occurrence of certain hereditary tumours, but they also set the stage for the development of anti-cancer drugs that specifically target activated oncogenes.

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Genome Exploitation : Data Mining the Genome

Data Mining the Genomes, is the 23rd volume of the Stadler Symposia series published by Springer, which have served over many years as a comprehensive collection of current trends and emerging hot topics in the field of genetics. Data Mining the Genomes summarizes the progress in bioinformatics and computational biology in data mining the vast amount of exciting information emerging from studies of plant and animal genomes, with authoritative analytical reviews specialized enough to be attractive to professional researchers, yet also appealing to the wider audience of scientists in related disciplines.

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Genetics and regulation of nitrogen fixation in free-Living bacteria

This book is the second volume of a seven-volume series, which covers all fields of research related to nitrogen fixation - from basic studies through applied aspects to environmental impacts. Volume II provides a comprehensive and detailed source of information concerning the genetics and regulation of biological nitrogen fixation in free-living prokaryotes.

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Gene Expression and Regulation

This book offers a comprehensive look into the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field. Presented in the following five sections, this book covers a full spectrum of topics: The History; The Machinery; The Regulators; The Genome; and Special Topics. The Machinery section covers the transcriptional apparatus and general transcription factors. The Regulators section examines selected gene-specific transcription factors important to regulating gene expression. The Genome section covers issues relevant to the behavior of the genome in relation to gene regulation. The Special Topics section discusses several selected topics ranging from bacterial and plant gene expression to DNA topology and interference RNA. The book’s focus is on scientific concepts and issues, rather than specific organisms or experimental approaches.

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GDPR and biobanking : Individual rights, Public interest and research regulation across Europe

This book focuses on the discrepancies in biobank research regulations that are among the most significant hurdles to effective research collaboration.

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