الصفحة 6
الصفحة 6
Acute Myelogenous Leukemia
The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. Bringing together new concepts and findings in the basic and clinical science of AML, the book emphasizes the molecular basis for new therapies that stand to have the greatest potential impact on the clinical face of these diseases. The text provides insights into selected novel strategies currently and prospectively being developed, including interruption of specific signal transduction pathways, modulation of gene expression, attempts to reinstate differentiation, and immunomodulation.
A theoretical and clinical study about multiple sclerosis
Multiple sclerosis is a one of those diseases such as Alzheimer in which no cure excites yet, any type of degradation in the neurological system is hard to restore, and more difficult in such a disease that it has a wide range of symptoms from the eye injury till some difficulty in walking to many other symptoms in which we will highlight in our project to increase public health awareness to consider such a relatively unknown disease in differential diagnosis...
A Study about Prevalence of Thalassemia Complications in Syrian Patients
Inherited haemoglobin disorders, including thalassemia and sickle-cell disease, are the most common monogenic diseases worldwide. Several clinical forms of α-thalassemia and β-thalassemia, including the co-inheritance of β-thalassemia with haemoglobin E resulting in haemoglobin E/β-thalassemia, have been described. The disease hallmarks include imbalance in the α/β-globin chain ratio, ineffective erythropoiesis, chronic hemolytic anemia, compensatory hemopoietin expansion, hypercoagulability, and increased intestinal iron absorption. The complications of iron overload, arising from transfusions that represent the basis of disease management in most patients with severe thalassemia. The mature Hb molecule is a tetramer composed of 2 a-globin and 2 b-globin polypeptides, which assemble, along with a heme prosthetic group, to form the complete molecule.
