الصفحة 6
الصفحة 6
Cytokines in the Genesis and Treatment of Cancer
Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. Divided into four sections, the volume’s first three parts focus on cytokines in the genesis of cancer. The final section describes the notable progress — both in animal models and humans — in demonstrating the use of cytokine or anticytokine therapies for the prevention and treatment of cancer. Cytokines in the Genesis and Treatment of Cancer brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer. Together, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field.
Cyclotomic Fields and Zeta Values
Cyclotomic fields have always occupied a central place in number theory, and the so called "main conjecture" on cyclotomic fields is arguably the deepest and most beautiful theorem known about them. It is also the simplest example of a vast array of subsequent, unproven "main conjectures'' in modern arithmetic geometry involving the arithmetic behaviour of motives over p-adic Lie extensions of number fields. These main conjectures are concerned with what one might loosely call the exact formulae of number theory which conjecturally link the special values of zeta and L-functions to purely arithmetic expressions.
Curcumin : clinical uses, health effects and potential complications
Curcumin is a natural product with polyphenolic structure. It is used in therapeutic remedies alone or in combination with other natural substances. Many researchers are investigating it because of its biological activities such as: anti-inflammatory, anti-cancer, anti-protozoal, anti-viral, anti-bacterial and has been found to be effective for treatment of Alzheimer, depression, headaches, fibromyalgia, leprosy, fever, menstrual problems, water retention, worms and kidney problems etc. It is an active ingredient in dietary spice, turmeric. It has reactive functional groups: a diketone moiety and two phenolic groups. Despite its unique biological activities, it suffers from some shortcomings which include: gastrointestinal problems, poor bioavailability due to its poor absorption, short half-life, poor solubility in aqueous solutions, rapid systemic elimination and antithrombotic activity which can interfere with blood clotting. The first chapter of this book reviews the different delivery systems used for incorporation of curcumin and its derivatives, release kinetics and up to date in vivo results. Chapter two discusses curcumin nano and microencapsulation and its implications on clinical uses.
Cornea and External Eye Disease : Corneal Allotransplantation, Allergic Disease and Trachoma
The 8 recurring volumes of the "Essentials in Ophthalmology" series cover the most recent developments in one of eight subspecialties in Ophthalmology.
Continuum Mechanics using Mathematica® : Fundamentals, Applications and Scientific Computing
This book's methodological approach familiarizes readers with the mathematical tools required to correctly define and solve problems in continuum mechanics. The book covers essential principles and fundamental applications, and provides a solid basis for a deeper study of more challenging and specialized problems related to elasticity, fluid mechanics, plasticity, materials with memory, piezoelectricity, ferroelectricity, magneto-fluid mechanics, and state changes.
Constructing Correct Software
Central to Formal Methods is the so-called Correctness Theorem which relates a specification to its correct Implementations. This theorem is the goal of traditional program testing and, more recently, of program verification (in which the theorem must be proved). Proofs are difficult, though even with the use of powerful theorem provers. This volume explains and illustrates an alternative method, which allows the construction of (necessarily correct) algorithms from a specification using algebraic transformations and refinement techniques which prevent the introduction of errors. Based on teaching material used extensively at Loughborough University, John Cooke introduces the basics, using simple examples and lots of detailed working (which can often be re-used). Constructing Correct Software will provide invaluable reading for students and practitioners of Computer Science and Software Engineering to whom correctness of software is of prime importance.
Concurrency Theory : Calculi an Automata for Modelling Untimed and Timed Concurrent Systems
Concurrency Theory is a synthesis of one of the major threads of theoretical computer science research focusing on languages and graphical notations for describing collections of simultaneously evolving components that interact through synchronous communication. The main specification notation focused on in this book is LOTOS. An extensive introduction to this particular process calculus is given, highlighting how the approach differs from competitor techniques, such as CCS and CSP.
Conceptual Modelling in Information Systems Engineering
Conceptual modeling has always been one of the cornerstones for information systems engineering as it describes the general knowledge of the system in the so-called conceptual schema.It contiant data modeling, goal-oriented modeling, agent-oriented modeling, and process-oriented modeling. Overall, the contributions reflect the most important developments and application areas of conceptual modeling in recent years, and they also pinpoint trends in conceptual modeling for the next decade.
Computer Aided Pharmaceutics and Drug Delivery : An Application Guide for Students and Researchers of Pharmaceutical Sciences
Examines the role of computer-assisted techniques for discovering, designing, optimizing and manufacturing new, effective, and safe pharmaceutical formulations and drug delivery systems. The book discusses computational approaches, statistical modeling and molecular modeling for the development and safe delivery of drugs in humans. The application of concepts of QbD (Quality by Design), DoE (Design of Experiments), artificial intelligence and in silico pharmacokinetic assessment/simulation have been made a lot easier with the help of commercial software and expert systems. This title provides in-depth knowledge of such useful software with illustrations from the latest researches. The book also fills in the gap between pharmaceutics and molecular modeling at micro, meso and maro scale by covering topics such as advancements in computer-aided Drug Design (CADD), drug-polymer interactions in drug delivery systems, molecular modeling of nanoparticles and pharmaceutics/bioinformatics.
Computational Textile
This edited book collects a number of representative applications of computational techniques in textile and garment industry. These applications cover the following issues: Textile quality assessment by image analysis, Modeling and simulation of textile structures, Computer aided garment design, Computerized textile management and textile Supply Chain, Textile quality subjective and objective evaluation; Computational thermal bioengineering of textiles and clothing; Computational biomechanical engineering of textiles and clothing.
Computational genetics and genomics : Tools for understanding disease
The authors introduce a new computational approach that makes it possible to identify the genetic basis for differences in physiological or pathological responses among inbred mouse strains, thus facilitating more rapid genetic discovery
Commercial and apartment building
Residential Commercial Building Project. Built in Morata City, Damascus, Syria. This Project consists of a building made up of: One Basement, One Parking Lot, Five Commercial Floors, Seven Apartments, A Hall Made for Sports.
Color Doppler US of the Penis
This book provides a comprehensive reference and practical guide on the application of US to penile diseases and conditions. The topics covered include erectile dysfunction, Peyronie’s disease, priapism, trauma, tumors, the postoperative penis, inflammation, and fibrosis.
Mathematical Foundation of Geodesy : Selected Papers of Torben Krarup
This volume contains selected papers by Torben Krarup, one of the most important geodesists of the 20th century. His writings are mathematically well founded and scientifically relevant. In this impressive collection of papers he demonstrates his rare innovative ability to present significant topics and concepts. Modern students of geodesy can learn a lot from his selection of mathematical tools for solving actual problems. The collection contains the famous booklet "A Contribution to the Mathematical Foundation of Physical Geodesy" from 1969, the unpublished "Molodenskij letters" from 1973, the final version of "Integrated Geodesy" from 1978, "Foundation of a Theory of Elasticity for Geodetic Networks" from 1974, as well as numerous trend setting papers on the theory of adjustment.
Matematica generale con il calcolatore
By introducing mathematical objects, it teaches students how to use a computer to perform numerical and symbolic calculations, define a function and calculate its values, plot and explore graphs, and execute simple algorithms. The course is rich in examples, applications, and models, drawn from economics, physics, biology, statistics, and mathematics itself. The analysis of these models constitutes, in a certain sense, the true purpose of the mathematical theory covered. Automatic calculation tools (mathematics software, spreadsheets) are used extensively to explore and illustrate concepts and properties. Mathcad® software, in particular, was used, both as a calculation tool and as a simple yet powerful programming language. Considerable space is devoted to approximation, emphasizing the distinction between numerical and symbolic calculation; to algorithms as a synthesis of the syntactic and semantic aspects of mathematical objects; and to computer simulation, interpreted as a "physical" experiment and a source of conjecture. The ability to use a calculator marks a sort of "democratization" of mathematics: even complex results, which have always required a broad background of knowledge and laborious calculations, are now quickly accessible to anyone who understands the meaning of mathematical objects and knows how to use the syntax.
Matematica e cultura 2005 = Mathematics and culture 2005
E si parla di arte; oltre che di Pizzinato, di Pollock, grazie alla collaborazione della Guggenheim Collection di Venezia.E si parla di architettura, dalla topologia ai progetti di Ghery e di Renzo Piano.E di modelli matematici per la lotta contro il cancro, contro l’AIDS.Di come la matematica può aiutare a prevenire e intervenire. E si parla di matematica della guerra e di come la matematica possa aiutare a proteggere l’ambiente. Nel gennaio 2005, scrivendo queste parole, diventa di grande e drammatica attualità l’utilizzo dei modelli matematici per la meteorologia. Prevedere per salvare.
Mass Vaccination : Global Aspects - Progress and Obstacles
Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.
Manifestations dermatologiques des maladies du système hématopoïétique et oncologie dermatologique : Dermatologie et médecine ; Vol.3 = Dermatological manifestations of diseases of the hematopoietic system anddermatological oncology : Dermatology and medicine ; Vol.3
Provides an update on all the disorders of the hematopoietic system with dermatological expression or with a cutaneous origin. Myeloproliferative and myelodysplastic syndromes, leukemias, lymphomas and cutaneous histiocytoses are thus widely described in the light of the latest clinical (classification, new entities) and therapeutic advances.
Manifestations dermatologiques des connectivites vascularites et affections systémiques apparentées : Dermatologie et médecine = Dermatological manifestations of connectivitis, vasculitis and related systemic conditions: Dermatology and medicine
Deals with all the skin and mucous membrane manifestations observed during the various so-called systemic, common or rare diseases. Each chapter covers in an exhaustive and original way the clinical, anatomopathological and therapeutic knowledge essential to the practice of dermatology and internal medicine. The work is abundantly illustrated with color clinical iconography, carefully selected for its clinical representativeness. The didactic anatomopathological figures have been enriched with explanatory diagrams facilitating their reading by the practitioner unfamiliar with dermatological histology. Produced by a group of leading authors in their field, this book is intended for dermatologists, rheumatologists and internists as well as all professionals concerned with systemic diseases and internal medicine.
Managing Closed-Loop Supply Chains
Introduction Closing supply chains refers to taking care of items once they are no longer desired or can no longer be used by their user. Smart management of closed-loop supply chains means profitable recovery of value from these items (products, functional components, materials or packaging). The company closing the supply chain may be the original equipment manuf- turer (OEM), a distribution partner or a third party not involved in the f- ward distribution. In recent years, the management of closed-loop supply chains has gained importance because of increased legislation on producer respon- bility, requiring companies to take back products from customers and to organize for proper recovery and disposal. This legislation is partially due to increased awareness of environmental issues. However, smart com- nies have also understood that returned products often contain lots of value to be recovered. They manage closed-loop supply chains simply because it is a profitable business proposition.
