الصفحة 6
الصفحة 6
Memory B-cells : Methods and protocols
Details in methods to assess memory B cell formation and function in mice and humans. Chapters guide readers through tetramer-based methods to assess antigen-specific memory B cell dynamics in humans and mice in different vaccine, next-generation deep-sequencing, single-cell techniques to assess epigenomic, VDJ landscapes, lymph node aspirates from humans, advanced imaging, murine models to determine memory B cells formation, and bioinformatic techniques and in silico modelling of memory b cell formation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Mediterranean Island Landscapes : Natural and Cultural Approaches
Mediterranean islands exhibit many similarities in their biotic ecological, physical and environmental characteristics. There are also many differences in terms of their human colonization and current anthropogenic pressures. This book addresses in three sections these characteristics and examines the major environmental changes that the islands experienced during the Quaternary period. The first section provides details on natural and cultural factors which have shaped island landscapes. It describes the environmental and cultural changes of the Holocene and their effects on biota, as well as on the current human pressures that are now threats to the sustainability of the island communities. The second section focuses on the landscapes of the largest islands namely Sicily, Sardinia, Corsica, Cyprus, Crete, Malta and the Balearics. Each island chapter includes a special topic reflecting a particular characteristic of the island. Part three presents strategies for action towards sustainability in Mediterranean islands and concludes with a comparison between the largest islands.
Medicinal plants : From farm to pharmacy
Discuss current research on medicinal plants that connects traditionally accumulated botanical wisdom with current bioprospecting trends and (pre-clinical studies Provide an account of recent research activities on select medicinal plants from various phytogeographical regions all over the world Cater to the interest of a wide range of readers including lay enthusiasts, traditional practitioners as well as research and clinical professionals
Medicina fisica e riabilitativa nei disturbi di equilibrio = Physical and rehabilitative medicine in balance disorders
Balance disorders are very common in the population: particularly frequent over the age of 40, are the first motivation for a medical examination after the age of 65 and frequently tend to become chronic. Balance disorders are symptoms of system dysfunction vestibular, complex sensory-psycho-motor system, whose task is that to control the activity of the antigravity muscles to maintain the erect station, of the oculomotor ones to allow the stabilization of the visual field during movement, and the neurovegetative functions they have relationship with standing and movement. Whether the vestibular system provides the information necessary for the check-up of the erect position, the rachis realizes it through a "stability dynamic ", allowed by its structural characteristics proprioception the spine is also a fundamental sensor for controlling balance ; therefore the techniques of physical and rehabilitative medicine and of manual medicine represent a powerful tool for curing ailments equilibrium. This volume comes from the comparison between a physiatrist and an audiologist, who for 15 years have integrated their clinical experience and therefore proposes a new one inter-specialist approach to the diagnostic and therapeutic problems of patients with balance disorders.
Medical Pharmacology and Therapeutics
Provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA. This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class. Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines.
Medical image synthesis : Methods and clinical applications
Image synthesis across and within medical imaging modalities is an active area of research with broad applications in radiology and radiation oncology. This book covers the principles and methods of medical image synthesis, along with state-of-the-art research. First, various traditional non-learning-based, traditional machine-learning-based, and recent deep-learning-based medical image synthesis methods are reviewed. Second, specific applications of different inter- and intra-modality image synthesis tasks and of synthetic image-aided segmentation and registration are introduced and summarized, listing and highlighting the proposed methods, study designs, and reported performances with the related clinical applications of representative studies. Third, the clinical usages of medical image synthesis, such as treatment planning and image-guided adaptive radiotherapy, are discussed. Last, the limitations and current challenges of various medical synthesis applications are explored, along with future trends and potential solutions to solve these difficulties.
Medical biotechnology, biopharmaceutics, forensic : science and bioinformatics
Covers a range of topics on exploiting Nigeria’s mega biodiversity for food security and health; DNA forensic science and its applications; medical biotechnology and biopharmaceutics; medicinal and underutilized plants; impact and mitigation of antibiotic resistance; bioinformatics applications; medical insect biotechnology; etc. The book will be useful reference material for the scientists and researchers working in the fields of nutraceuticals, molecular diagnostics and DNA forensics, biopharmaceuticals and medical biotechnology, nanotechnology, antimicrobials from indigenous plant species, bioinformatics, etc.
Mechanisms of Angiogenesis
Is it advisable to go back from bedside to the bench? During the last decade, few topics encountered such a broad interest in bio- gy and medicine as angiogenesis. The amazing ability of the body to restore blood flow by induction of blood vessel growth as part of an adaptive process has alarmed physicians dealing with diseases in which angiogenesis is either exaggerated (as in tumors) or too slow (as in ischemic diseases of heart and brain). Not surprisingly, pro- and antiangiogenic strategies have found their way into clinical trials. For instance, for the USA, the NIH website in early 2004 displayed 38 clinical studies involving either pro- or antiangiogenic th- apies. Given the expected overwhelming wealth of clinical data, the question may be asked whether further exploration of biological mechanisms is required or whether results from the bedside are instructive enough to proceed. This question depends also on the progress of pro- and antiangiogenic clinical trials. In the following, I give a short overview about some of the progress that has been made in this field. Since Judah Folkman proposed antiangiogenic tumor therapy thirty years ago, it has become increasingly evident that agents which interfere with blood vessel formation also block tumor progression. Accordingly, antiangiogenic therapy has gained much attention as a potential adjunct to conventional c- cer therapy.
Meat Biotechnology
The main goal of this book is to provide the reader with the recent developments in biotechnology and their applications in the meat processing chain. To achieve this goal, the book is divided into four parts. The first part deals with the use of modern biotechnology applied to farm animals. The second part focuses on the recent biotechnological developments in starter cultures for better meat fermentation. The third part discusses current approaches to improve the quality and nutritional properties of meats. The final part presents the latest advances in protection against foodborne pathogens, and other recent trends in the field. Written by distinguished international contributors, this book brings together the advances in such varied and different biotechnological topics
Meaning-Making for Living : The Emergence of the Presentational Self in Children’s Everyday Dialogues
This Brief analyzes the dynamics in which children’s selves emerge through their everyday activities of meaning construction, both in their relationships with family and within school education. It begins with a discussion of new psychological inquiries into children's selves and builds upon the innovative theoretical notion of the Presentational Self, developed by the author over the last decade. The book illustrates how the observation of children’s meaning construction in their everyday lives becomes a starting point for theoretical and empirical inquiries into child development and gives a framework that promotes new inquiries in this area. The book describes the Presentational Self Theory as a sense of how the notion of the Self is being worked upon in everyday life encounters. Chapters feature in-depth analyses of exchanges between adults and children in the Japanese cultural context.
MDATA : A New Knowledge Representation Model: Theory, Methods and Applications
This book introduces a new knowledge representation model called MDATA (Multi-dimensional Data Association and inTelligent Analysis). By modifying the representation of entities and relations in knowledge graphs, dynamic knowledge can be efficiently described with temporal and spatial characteristics. The MDATA model can be regarded as a high-level temporal and spatial knowledge graph model, which has strong capabilities for knowledge representation. This book introduces some key technologies in the MDATA model, such as entity recognition, relation extraction, entity alignment, and knowledge reasoning with spatiotemporal factors. The MDATA model can be applied in many critical applications and this book introduces some typical examples, such as network attack detection, social network analysis, and epidemic assessment.
Mathematics of Financial Markets
This book presents the mathematics that underpins pricing models for derivative securities, such as options, futures and swaps, in modern financial markets. The idealized continuous-time models built upon the famous Black-Scholes theory require sophisticated mathematical tools drawn from modern stochastic calculus. However, many of the underlying ideas can be explained more simply within a discrete-time framework. This is developed extensively in this substantially revised second edition to motivate the technically more demanding continuous-time theory, which includes a detailed analysis of the Black-Scholes model and its generalizations, American put options, term structure models and consumption-investment problems. The mathematics of martingales and stochastic calculus is developed where it is needed.
Iron Nutrition in Plants and Rhizospheric Microorganisms
This book uses an interdisciplinary approach to provide a comprehensive review on the status of iron nutrition in plants. International scientists discuss research on acquisition of iron by strategy I and strategy II plants. These reviews summarize a variety of plant species and include both laboratory and field observations. Topics covered in this book include: plants as a source of iron for animals and humans, iron translocation in the plants, iron-stimulated activities that influence crop yield and fruit tree productivity, iron uptake by plants as influenced by microorganisms (i.e. free living soil microorganisms, symbiotic nitrogen-fixing and pathogenic bacteria), the role of plant hormones in iron transport, iron-metal competition in phytoremediation, root zone activities involving interactions between minerals and organic matter, the role of microbial siderophores in rhizospheric iron cycling, iron storage as phytoferritin, proteomic and metabolic studies associated with iron stress response, methods for studying iron metabolism including stable isotopes, and the correction of iron deficiency through the use of synthetic or natural chelates.
IoT-enabled Smart Healthcare Systems, Services and Applications
In IoT-Enabled Smart Healthcare Systems, Services and Applications, an accomplished team of researchers delivers an insightful and comprehensive exploration of the roles played by cutting-edge technologies in modern healthcare delivery. The distinguished editors have included resources from a diverse array of learned experts in the field that combine to create a broad examination of a rapidly developing field.
IOT glass tempering controller
The Internet of things (IoT) subject speaks to a thought for the electronic-mechanical arrangement of devices to detect and gather data from the encompassing environmental factors and a short time later share that data over the Internet where it will, in general, be arranged and utilized for various purposes. This project will show the use of Iot in the process of Harding glass to accomplish a well-tempered glass and solving the problem of arching glass which is caused because of the difference of the temperature in the upper and lower heat, Iot will help in monitoring and controlling the temperature through blynk program.
IOT control and surveillance system
An automated system is a combination of both software and hardware which is designed and programmed to work automatically without the need of any human operator to provide inputs and instructions for each operation. The Internet of Things (IoT) is a network of connected things. These ‘things’ (devices) communicate with each other using machine to machine communication (M2M). Information is traversed between devices so that processes can be automated, without the need for human intervention. By reducing the number of people involved in a business process, several advantages arise, including improved accuracy and up-time. We will build an IoT automated system to control access of humans and vehicles to a warehouse based on biometrics and image recognition techniques.
IoT and AI Technologies for Sustainable Living : A Practical Handbook
Brings together all the latest methodologies, tools and techniques related to the Internet of Things and Artificial Intelligence in a single volume to build insight into their use in sustainable living. The areas of application include agriculture, smart farming, healthcare, bioinformatics, self-diagnosis systems, body sensor networks, multimedia mining, and multimedia in forensics and security. Provides a comprehensive discussion of modeling and implementation in water resource optimization, recognizing pest patterns, traffic scheduling, web mining, cyber security and cyber forensics. It will help develop an understanding of the need for AI and IoT to have a sustainable era of human living. The tools covered include genetic algorithms, cloud computing, water resource management, web mining, machine learning, block chaining, learning algorithms, sentimental analysis and Natural Language Processing (NLP).
Investigations Into the Phenomenology and the Ontology of the Work of Art : What are Artworks and How Do We Experience Them?
This book investigates the nature of aesthetic experience and aesthetic objects. Written by leading philosophers, psychologists, literary scholars and semioticians, the book addresses two intertwined issues. The first is related to the phenomenology of aesthetic experience: The understanding of how human beings respond to artworks, how we process linguistic or visual information, and what properties in artworks trigger aesthetic experiences. The examination of the properties of aesthetic experience reveals essential aspects of our perceptual, cognitive, and semiotic capacities. The second issue studied in this volume is related to the ontology of the work of art: Written or visual artworks are a specific type of objects, containing particular kinds of representation which elicit a particular kind of experience.
Inventive communication and computational technologies ; Proceedings of ICICCT 2020
This book gathers selected papers presented at the 4th International Conference on Inventive Communication and Computational Technologies (ICICCT 2020), held on 28–29 May 2020 at Gnanamani College of Technology, Tamil Nadu, India. The respective contributions highlight recent research efforts and advances in a new paradigm called ISMAC (IoT in Social, Mobile, Analytics and Cloud contexts). The topics covered include the Internet of Things, Social Networks, Mobile Communications, Big Data Analytics, Bio-inspired Computing and Cloud Computing. Given its scope, the book is chiefly intended for academics and practitioners working to resolve practical issues in this area.
Introduction to toxicology
Charts the evolution of the field of toxicology, from the use of natural toxins by ancient tribes through the developments established by Paracelsus, and progresses through to the current topics in the public interest. For centuries, the study of toxicology has fascinated students. The book begins with basic toxicological principles, including an historical summary, dose-response relationships (NEW chapter), exposure-response relationships (NEW chapter), disposition, and metabolism of xenobiotic toxic substances. Other important new chapters include target organ toxicity, toxicity of carcinogenic agents and new and updated concepts in toxicity testing, and antidotes and treatment of poisonings. In all, nine new or expanded chapters from the third edition are advanced. Current concerns about the effects of therapeutic drugs, carcinogens, industrial toxins, pesticides, and herbicides on human health, animal welfare, and the stability and maintenance of the ecosystem continue to highlight toxicology as an important and growing scientific discipline.
