Entry Inhibitors in HIV Therapy
The introductory chapters of this book present an overview of entry inhibitors, review current knowledge of how Env mediates entry, and discuss the challenge of genetic diversity in this region of the viral genome. Subsequent chapters feature current information on individual classes of entry inhibitors that target each step of the virus entry pathway, from attachment to membrane fusion. There is an emphasis on the complex determinants of entry inhibitor susceptibility, resistance mechanisms, the need for clinical phenotyping, and how these issues create new challenges for antiretroviral therapy. Encouraging pre-clinical studies of entry inhibitors as microbicidesare also discussed. The final chapters highlight the current status of entry inhibitors in clinical studies, the major milestone achieved with FDA approval of enfuvirtide, and review drug development, past and present.
Entrepreneurship and innovation : Theory, practice and context, 4th
Provides an overview of the theory, Practice and context of entrepreneurship and innovation at both the industry and firm level. It provides a foundation of ideas and understandings designed to shape the reader’s thinking and behaviour to better appreciate the role of innovation and entrepreneurship in modern economies, And to recognise their own abilities in this regard. The book provides the reader with an overview of these elements and how they combine to create new value in the market.
Embedded Software and Systems ; 3rd International Conference, ICESS 2007, Daegu, Korea, May 14-16, 2007, Proceedings
This book introduces sections on embedded architecture, embedded hardware, embedded software, HW-SW co-design and SoC, multimedia and HCI, pervasive/ubiquitous computing and sensor network, power-aware computing, real-time systems, security and dependability, and wireless communication.
Eigenvalues, Inequalities, and Ergodic Theory
A problem of broad interest – the estimation of the spectral gap for matrices or differential operators (Markov chains or diffusions) – is covered in this book. The area has a wide range of applications, and provides a tool to describe the phase transitions and the effectiveness of random algorithms. In particular, the book studies a subset of the general problem, taking some approaches that have, up till now, only appeared largely in the Chinese literature.Eigenvalues, Inequalities and Ergodic Theory serves as an introduction to this developing field, and provides an overview of the methods used, in an accessible and concise manner.
Effect of Clove essential oil and Rosemary aqueous extract for future promising triple acting gel
In this study, antimicrobial properties of rosemary essential oil (Rosmarinus officinalis-REO), rosemary aqueous extract, clove essential oil (Syzygium aromaticum-CEO) and their mixtures (REO/CEO) at 10% and 20% concentration for each one have been evaluated. The agar well diffusion method has been used for screening the antimicrobial activity against Staphylococcus aureus, Staphylococcus albus, Streptococcus, Enterococcus Salmonella, Escherichia coli, Acinetobacter, Pseudomonas aeruginosa, Candida albicans In Staph. Aureus, Salmonella, E.coli, Acinetobacter and p.aeruginosa...
Diversity and Evolution of Butterfly Wing Patterns : An Integrative Approach
is book facilitates an integrative understanding of the development, genetics and evolution of butterfly wing patterns. To develop a deep and realistic understanding of the diversity and evolution of butterfly wing patterns, it is essential and necessary to approach the problem from various kinds of key research fields such as “evo-devo,” “eco-devo,” ”developmental genetics,” “ecology and adaptation,” “food plants,” and “theoretical modeling.”
Distributed computing in sensor systems Vol. 4026 ; 2nd IEEE International Conference, DCOSS 2006, San Francisco, CA, USA, June 18-20, 2006, Proceedings
The book constitutes the refereed proceedings of the Second International Conference on Distributed Computing in Sensor Systems, DCOSS 2006, held in San Francisco, California, USA in June 2006. The papers focus on distributed computing issues in large-scale networked sensor systems, including systematic design techniques and tools; they cover topics such as distributed algorithms and applications, programming support and middleware, data aggregation and dissemination, security, information fusion, lifetime maximization, and localization.
Digital Transformation in Norwegian Enterprises
Presents a number of case studies on digital transformation in Norway, one of the fore-runners in the digital progress index established by the European Commission in 2020. They explore the process of adoption, diffusion and value generation from digital technologies, and how the use of different digital solutions has enabled Norwegian enterprises to digitally transform their operations and business models.
Digital dental implantology : From treatment planning to guided surgery
Describes the fusion of CBCT and CAD/CAM technologies for the purpose of surgical dental treatments and explains the advantages and applications of this digital approach for implant placement procedures and other oral surgical protocols.
Digital cities III : Information technologies for social capital: Cross-cultural Perspectives ; 3rd international digital cities workshop, Amsterdam, The Netherlands, September 18-19, 2003, Revised Selected Papers
Digital cities constitutes a multidisciplinary field of research and development, where researchers, designers and developers of communityware interact and collaborate with social scientists studying the use and effects of these kinds of infrastructures and systems in their local application context. The field is rather young. After the diffusion of ICT in the world of organizations and companies, ICT entered everyday life. And this also influenced ICT research and development. The 1998 Workshop on Communityware and Social Interaction in Kyoto was an early meeting in which this emerging field was discussed.
Diffusion-Weighted MR Imaging of the Brain
Diffusion-weighted MR imaging is widely accepted as a means to identify stroke, thus enabling rapid and effective treatment. Over the past four years, these expert authors have presented over 30 exhibits and scientific reports on diffusion-weighted imaging at the RSNA and the American Society of Neuroradiology (ASNR), and more than 10 of these presentations have been recognized by specific awards. Diffusion-Weighted MR Imaging of the Brain’s chapters range from basic principles to interpretation of diffusion-weighted MR imaging and specific disease.
Diffusion in solids : Fundamentals, methods, materials, diffusion-controlled processes
This book first gives an account of the central aspects of diffusion in solids, for which the necessary background is a course in solid state physics. It then provides easy access to important information about diffuson in metals, alloys, semiconductors, ion-conducting materials, glasses and nanomaterials.
Diffusion in Condensed Matter : Methods, Materials, Models
Diffusion as the process of particle transport due to stochastic movement is a phenomenon of crucial relevance for a large variety of processes and materials. This comprehensive, handbook-style survey of diffusion in condensed matter gives detailed insight into diffusion as the process of particle transport due to stochastic movement. Leading experts in the field describe in 23 chapters the different aspects of diffusion, covering microscopic and macroscopic experimental techniques and exemplary results for various classes of solids, liquids and interfaces as well as several theoretical concepts and models. Students and scientists in physics, chemistry, materials science, and biology will benefit from this detailed compilation.
Difficoltà in matematica : Osservare, interpretare, intervenire = Difficulty in mathematics : Observe, interpret, intervene
In a school context, difficulties in mathematics are an important phenomenon both for its diffusion and for the consequences it has at various levels: from the personal distress experienced by many students, to the negative attitude that large sections of the population build towards our discipline, up to the drop in enrollment in scientific degree courses. Faced with these difficulties, which often manifest themselves in behaviors such as giving up trying or responding at random, the didactic action aimed at recovery is generally a local action, which arises from the identification of errors and then intervenes on knowledge deemed necessary to respond correctly. But this type of intervention generally proves to be unsuccessful, and the teacher - together with the pupil - develops a sense of helplessness and frustration.
Designing Ubiquitous Information Environments : Socio-Technical Issues and Challenges; IFIP TC8 WG 8.2 International Working Conference, August 1-3, 2005, Cleveland, Ohio, U.S.A.
The book brings in diverse perspectives on ubiquitous information environments, from computer-supported collaborative work, institutional perspective, diffusion of innovation, management, sociology, individual cognition, and software engineering. It also covers a variety of technologies that make up ubiquitous information environments including RFID, wireless grid, GPS, mobile phones, and wireless local area network. The papers cover many contexts of ubiquitous computing including personal use, library, automobile, healthcare, police, professional knowledge work, remote diagnostics of machines, and marketing, attesting to the wide range of potential of ubiquitous information environments.
Design Patterns for eScience
There is much additional software including many versions of the case study as it gets built up and progressively refactored using design patterns. There will be a home web-site for this book which will contain up-to-date information about the software and other aspects of the case study.
Defects in High-k Gate Dielectric Stacks : Nano-Electronic Semiconductor Devices
One of the key obstacles to high-k integration into Si nano-technology are the electronic defects in high-k materials. It has been established that defects do exist in high-k dielectrics and they play an important role in device operation. However, very little is known about the nature of the defects or about possible techniques to eliminate, or at least minimize them. Given the absence of a feasible alternative in the near future, well-focused scientific research and aggressive development programs on high-k gate dielectrics and related devices must continue for semiconductor electronics to remain a competitive income producing force in the global market.
Database and XMLTechnologies ; 5th International XML Database Symposium, XSym 2007, Vienna, Austria, September 23-24, 2007, Proceedings
This book discuss the use of and synergy between databases and XML. It provided theory and practice of XML data management and its applications. This volume also contains current research in XPath and XQuery processing, XML Updates, Temporal XML and Constraints.
Cosmic Ray Interactions, Propagation, and Acceleration in Space Plasmas
"The book consists of four Chapters. Chapter 1 shortly describes main properties of space plasmas and primary CR, different types of CR interactions with space plasmas components Chapter 2 considers the problem of CR propagation in space plasmas described by the kinetic equation and different types of diffusion approximations ,Chapter 3 is devoted to CR non-linear effects in space plasmas caused by CR pressure and CR kinetic stream instabilities with the generation of Alfvèn turbulence In Chapter 4 different processes of CR acceleration in space plasmas are considered: the development of the Fermi statistical mechanism, acceleration in the turbulent plasma, Alfven mechanism of magnetic pumping, induction mechanisms, acceleration during magnetic collapse and compression, cumulative acceleration mechanism near the zero lines of a magnetic field, acceleration in shear flows, shock-wave diffusion (regular) acceleration. The book ends with a list providing more than 1,300 full references, a discussion on future developments and unsolved problems, as well as Object and Author indexes. "
Coronaviruses : Methods and Protocols
Aims to describe a variety of techniques that reflects the wide range of research currently performed in the field of coronavirology, and begins with an overview of current understandings of coronavirus replication and pathogenesis to introduce specialists and non-specialists to the field. The rest of the book is divided into several sections of chapters beginning with those that describe identification, diagnosis, and study of the evolution of coronaviruses. The next few chapters discuss the preparation of cells and organ cultures useful in propagating coronaviruses and titration techniques, as well as techniques for analyzing virus functions that require purification of the viruses. The next chapters describe two commonly used reverse genetics techniques for coronaviruses, and techniques detailing identification of cellular receptors, binding profiles of viral attachment proteins, and virus-cell fusion. The final chapters cover a broad spectrum of techniques to identify virus-host protein-protein interactions, confirm the functional role of these proteins in virus replication, study host cell responses through genome-wide or pathway-specific approaches, and visualize virus replication complexes. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.



















