الصفحة 6
الصفحة 6
Estrogen Effects in Psychiatric Disorders
A number of studies, mostly focusing on estrogen replacement therapy in women, have reported beneficial actions of these hormones on various neurobiological and neuropathological parameters in health and disease. Recent research has focused on gender differences and there is increasing evidence that estrogens exert protective effects in schizophrenia. Hormonal fluctuations or lack of estrogen may increase the risk of depression among vulnerable women. Treatment of depression with estrogen may stabilize and restore disrupted homeostasis – as during post-partum, premenstrual, or perimenopausal conditions – and act as a psychomodulator to offset vulnerability to dysphoric mood when estrogen levels are significantly decreased, as in the case of postmenopausal women. Studies on the effect of estrogens on Alzheimer’s Disease are still rather controversial, they do, however, facilitate the hypothesis that estrogens may have a modifying effect on the onset and course of AD, at least in subgroups of patients.
Essentials of pharmacodynamics and drug action
Provides a comprehensive exploration of the dynamic field of pharmacology and its fundamental principles. It delves into the intricate interactions between drugs and the human body, focusing on pharmacokinetics, which explains the dynamics of drug actions in the body, and pharmacodynamics, which uncovers the mechanisms through which drugs exert their effects. The book also emphasizes the crucial aspects of therapeutics and gene-based therapy, shedding light on modern approaches to disease treatment.
Essentials of pharmaceutical analysis
Provides detailed information on the background, basic principles, and components of techniques used for the analysis of pharmaceuticals and biopharmaceuticals. Focusing on those analytical techniques that are most frequently used for pharmaceuticals, it classifies them into three major sections and 19 chapters, each of which discusses a respective technique in detail. Chiefly intended for graduate students in the pharmaceutical sciences, the book will familiarize them with the components, working principles and practical applications of these indispensable analytical techniques.
Essential Issues in SOC Design : Designing Complex Systems-on-Chip
SOC design is fast becoming the key area of focus that engineers and researchers from the Electronic Design Automation field are focusing on in their quest to further develop Integrated Circuit technology. The more systems and even networks that we can integrate on one piece of silicon, the faster, cheaper, more powerful and efficient the technology will become. Essential Issues in SOC Design contains valuable academic and industrial examples for those involved with the design of complex SOCs, all contributors are selected from a region of the world that is generally known to lead the "SOC-Revolution", namely Asia.
Equity Financing and Covenants in Venture Capital : An Augmented Contracting Approach to Optimal German Contract Design
Karoline Jung-Senssfelder presents the first augmented contracting analysis, focusing on the interaction of both, financial instruments and covenants, in the creation of incentives to the contracting parties. With a focus on the German market, she integrates the findings of her model-based theoretical and survey-based empirical analyses to derive value-adding implications for an incentive-compatible contract design in the German venture capital market.
Epigenetics in oncology
Covers the most recent advances in RNA/histone/DNA epigenetics in Oncology. RNA/histone/DNA epigenetics have been shown to play pivotal roles in cancer initiation, progression, maintenance and drug response/resistance, tumor microenvironment, cancer stem cell self-renewal, cancer metabolism, and tumor immune evasion. In particular, research in RNA cancer epigenetics has made impressive progress in the last few years. Individual chapters in Part I (focusing on RNA epigenetics) are devoted to RNA modifications in Cancer Metabolism and Microenvironment, Cancer Stem Cell Biology, Immune Surveillance, Solid Tumors and Tumor Immunity, and Hematopoietic Malignancies, as well as to RNA editing in Cancer. Chapters in Part II and III of the book focus on histone epigenetics and DNA epigenetics, respectively.
Environmental Governance of the Baltic Sea
This edited volume presents a comprehensive and coherent interdisciplinary analysis of challenges and possibilities for sustainable governance of the Baltic Sea ecosystem by combining knowledge and approaches from natural and social sciences. Focusing on the Ecosystem Approach to Management (EAM) and associated multi-level, multi-sector and multi-actor challenges, the book provides up-to-date descriptions and analyses of environmental governance structures and processes at the macro-regional Baltic Sea level.
Entrepreneurial Strategy : Starting, Managing, and Scaling New Ventures
This book focuses on explaining differences amongst organizations regarding various attributes, forms, and outcomes. By focusing on the “how” of new venture creation and management to produce well-established organizations, the authors aim to increase our understanding of the antecedents of most management research assumptions. New ventures are the source of most newly created jobs generated in an economy, new industries and markets, innovative products and services, and new solutions to economic, social, and environmental problems. However, most management research assumes a well-established organization as the starting point of their theorizing.
Entrepreneurial responses to chronic adversity : The bright, the dark, and the in between
Extends recent work on entrepreneurship in response to adverse events to explore entrepreneurial responses by people who face chronic adversity more deeply. Instead of focusing on the sort of responses intended to destroy the institutions that create and sustain chronic adversity, the authors are interested in how individuals use entrepreneurial action to find a way within these adverse constraints to improve their lives. They explore the positive outcomes arising from these entrepreneurial actions for the entrepreneurial actor and their family members as well as the negative consequences of these entrepreneurial responses to chronic adversity — outcomes that diminish others’ well-being.
Enhancing urban environment by environmental upgrading and restoration ; Proceedings of the NATO Advanced Research Workshop on enhancing urban environment : environmental upgrading of municipal pollution control facilities and restoration of urban waters, Rome, Italy from 6 - 9 November 2003.
As urban areas keep growing, water infrastructure ages, and the requirements on environmental protection become more rigorous, there is a continual need for upgrading water pollution control facilities and restoring degraded urban waters. Such issues are addressed in this book by focusing on five major topics: (a) Upgrading stormwater management facilities, (b) Retrofitting / upgrading combined sewer overflow (CSO) facilities, (c) Optimising/upgrading sewage treatment plant performance, (d) Urban stream restoration, and (e) Challenges in restoring urban environment. Each chapter contains some overview papers followed by research or case study papers. Besides presentations of new approaches and accomplishments in the field of upgrading and restoration, several papers provide analysis of vast needs in this field in several countries of Central and Eastern Europe, which either recently joined the European Union (EU) or are preparing for accession, and need to comply with the existing EU directives dealing with environmental protection. As such, this book will be of primary interest to researchers and university lecturers dealing with environmental upgrading and restoration, environmental planners from all levels of government, municipal engineers and politicians, and finally the private industry representatives (consultants, private utilities and environmental technology suppliers) searching for new business opportunities among the new or aspiring members of EU.
Engineering Statics
Focusing on practical applications knowledge, with numerous real-world examples, practice problems, and case studies throughout. It covers theory concisely and uses plain language and coverage that can be completed in a one-semester course. It also covers the related concepts required to take the Fundamentals of Engineering (FE) exam.
Energy Demand Challenges in Europe : Implications for policy, planning and practice
This book examines the role of citizens in sustainable energy transitions across Europe. It explores energy problem framing, policy approaches and practical responses to the challenge of securing clean, affordable and sustainable energy for all citizens, focusing on households as the main unit of analysis. The book revolves around ten contributions that each summarise national trends, socio-material characteristics, and policy responses to contemporary energy issues affecting householders in different countries, and provides good practice examples for designing and implementing sustainable energy initiatives. Prominent concerns include reducing carbon emissions, energy poverty, sustainable consumption, governance, practices, innovations and sustainable lifestyles.
Endourooncology : New Horizons in Endourology
Recent research and clinical work have demonstrated that the rapid urologic innovation in minimally invasive treatment is creating exciting new horizons in endourology. This sixth volume in the series Recent Advances in Endourology brings that knowledge to a wider audience, focusing on the new concept of endourooncology, which is the merging of endourology and oncology. In the surgical treatment of urologic malignancies, bipolarization - that is, radical extended resection or organ-sparing surgery - is making remarkable advances. Further developments in sophisticated reconstructive surgery using robotic systems and image-guided ablation technology will allow surgeons to formulate minimally invasive, tailor-made procedures for each patient with urologic cancer. In this book, the current status and future prospects of these new technologies are reviewed, illuminating their roles in the future of endourooncology.
Endogenous Public Policy and Contests
This book studies endogenous policy determination focusing on the role of interest groups and their lobbying efforts in the determination of public policy. Applying strategic contest theory, it clarifies the fundamental parameters that determine the behavior of the government and the interest groups - the two contestants for the "prizes" associated with public policy.
Electromagnetic Technologies in Food Science
Electromagnetic Technologies in Food Science examines various methods employed in food applications that are based on the entire electromagnetic (EM) spectrum. Focusing on recent advances and challenges in food science and technology, this is an up-to-date volume that features vital contributions coming from an international panel of experts who have shared both fundamental and advanced knowledge of information on the dosimetry methods, and on potential applications of gamma irradiation, electron beams, X-rays, radio and microwaves, ultraviolet, visible, pulsed light, and more.
Electroactive Polymers for Robotic Application : Artificial Muscles and Sensors
Electroactive polymers (EAPs) respond to electrical stimulation with large deformations. They are dynamic actuators which have attracted attention from an interdisciplinary audience of engineers and scientists. An enabling EAP technology is emerging which attempts to imitate the properties of natural muscle and which, as a result, can perform a unique function in a variety of biologically-inspired robotics applications. Electroactive Polymers for Robotics Applications covers the fundamental properties, modelling and demonstration of EAPs in robotic applications, focusing particularly on artificial muscles and sensors. Ionic Polymer–Metal Composite Actuators and Dielectric Elastomers are discussed within the book with chapters on their properties and their uses in robotics applications.
e-Learning : Nuovi strumenti per insegnare, apprendere, comunicare online = New tools to teach, learn, communicate online
Offers an overview of the evolution of online training, focusing both on the possible transformations made by new technologies on teaching, and on the more purely technical aspect, through the analysis of online training systems. The aim is to bring teachers, students and anyone who intends to learn more about a topic that, in many ways, still remains unknown to most of those who work in the world of education, to e-learning. The aim is to provide the opportunity to get in touch with the countless opportunities that new technologies offer to transform, improve and make teaching and learning more accessible, with a look at the future prospects of a sector that presents itself in constant evolution.
Einsteins Enigma or Black Holes in My Bubble Bath
Einstein's Enigma or Black Holes in My Bubble Bath tells the story of gravitation theory from the early historic origins to the latest developments in astrophysics, focusing on Albert Einstein's theory of general relativity and black-hole physics. Through engaging conversations and napkin-scribbled diagrams come tumbling the rudiments of relativity, spacetime and much of modern physics, narrated with high didactic and literary talent, and each embedded in casual lessons given by a worldly astrophysicist to his friend Alfie, a freelance organiser of proposals. Join the intellectual fun and exalt in the frothy ideas while vicariously taking relaxing baths in this magical bathtub.
Efficient Approximation and Online Algorithms : Recent Progress on Classical Combinatorial Optimization Problems and New Applications
This book provides a good opportunity for computer science practitioners and researchers to get in sync with current state-of-the-art and future trends in the field of combinatorial optimization and online algorithms. Recent advances in this area are presented focusing on the design of efficient approximation and on-line algorithms. One central idea in the book is to use a linear program relaxation of the problem, randomization and rounding techniques.
Effective Resource Management in Manufacturing Systems : Optimization Algorithms for Production Planning
Effective Resource Management in Manufacturing Systems aims to provide robust methods for achieving effective resource allocation and to solve related problems that occur daily and often generate cost overruns, specifically focusing on problems like resource levelling, sizing of machines and production layouts, cost optimization in production planning and scheduling. This approach is based on providing quantitative methods, covering both mathematical programming and algorithms, leading to high quality solutions for the analysed problems. Details of extensive experimentation is provided for the proposed techniques to put them in a practical perspective, so that, on the one hand, the reader can reproduce them, and, on the other hand, it appears clear how they can be implemented in real scenarios.
