الصفحة 6
الصفحة 6
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Inflammation and cancer : Methods and protocols

Discusses the latest findings on the development and characterization of representative research models for chronic immune-based diseases and inflammation-associated cancers.And covers biochemical, molecular, and cellular biological techniques that are commonly used to dissect the molecular mechanisms and cellular processes that drive the pathogenesis of certain disease states.

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Infections à papillomavirus : État des connaissances, pratiques et prévention vaccinale = Human papillomavirus infections : Current knowledge, practices and vaccination prevention

The impact of papillomavirus (HPV) infection is considerable. More than one in two women has been exposed to HPV in her lifetime and around 10% will develop a chronic infection. Of these, 20% will develop cervical cancer in the absence or failure of screening. In France, high-risk HPV infection causes 80,000 precancerous lesions, 3,400 cervical cancers and the death of 1,000 women every year. Smear screening performed at a regular rate and according to quality standards has resulted in a significant decrease in incidence and mortality over the past 20 years. However, despite this considerable success, the so-called preventable disease has not been eradicated; testing is a complex process that only benefits part of the population while those who benefit endure its weaknesses. Optimization of screening and treatment is now made possible by the use of innovative techniques including the smear in liquid suspension, the HPV test, and soon viral genotyping and molecular markers guaranteeing maximum protection. Because cervical cancer is the result of chronic HPV infection, we already have the extraordinary chance to prevent it with a prophylactic vaccine. This progress will have a major impact on our practices as it happens in a poorly prepared medico-sociological environment. This resolutely practical and educational book provides an overview of knowledge and perspectives on HPV infection and its associated pathologies while deciphering the new challenges and practices in the vaccine era.

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In Vivo Models of Inflammation ; Vol. II

In Vivo Models of Inflammation (Vol. 2) provides biomedical researchers in both the pharmaceutical industry and academia with a description of the state-of-the-art animal model systems used to emulate diseases with components of inflammation.

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In Vivo Models of Inflammation ; Vol. I

In Vivo Models of Inflammation (Vol. 1) provides biomedical researchers in both the pharmaceutical industry and academia with a description of the state-of-the-art animal model systems used to emulate diseases with components of inflammation.

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In Vivo Imaging of Cancer Therapy

In Vivo Imaging of Cancer Therapy addresses a variety of cutting-edge imaging techniques, including their use for best practice, and provides examples of results found in both pre-clinical and clinical studies. This comprehensive text covers the entire spectrum of in vivo imaging for oncology, including current approaches to detailed anatomic measurements, MR and optical spectroscopy, and molecular imaging techniques requiring exogenously administered imaging agents. The challenges and approaches to quantification are also outlined. The authors describe technologies and methods that are currently clinically available, and many that are still in a developmental stage or useful only in animal studies.

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Improving outcomes in oral cancer : A clinical and translational update

Brings together experts in the field of maxillofacial and head and neck oncology to provide a comprehensive clinical and translational update on oral cancer that focuses especially on prognosis. Readers will find up-to-date information on disease staging and the pathological, genetic, and surgical factors that affect patient outcomes.

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Improving Oral Health for the Elderly : An Interdisciplinary Approach

Improving Oral Health for the Elderly: An Interdisciplinary Approach examines in depth a crucial yet frequently overlooked indicator of seniors’ quality of life. By combining a lifespan approach to health with a biopsychosocial perspective on health disparities, this book places oral health in the larger context of physical and mental well-being.

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Immunosenescence

In this volume not only the mechanisms responsible for immune ageing in humans but consider what might be accomplished to redress the erosion of immune competence with age.

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Immune mediators in cancer : Methods and protocols

Provides a comprehensive collection of classic and cutting-edge methodologies as well as bioinformatics and genome-editing approaches that are used to quantify immune mediators and analyze their function and biological activity in cancer cells and tissues. Beginning with a section on the detection of immune mediators in samples, the volume continues with sections covering cytokine bioassays, the expression and regulation of immune mediators in cancer cells, and methods to navigate the enormous datasets created by modern DNA and RNA sequencing and proteomic technology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Immobilisation of DNA on Chips II

DNA chips are gaining increasing importance in different fields ranging from medicine to analytical chemistry with applications in the latter in food safety and food quality issues as well as in environmental protection. In the medical field, DNA chips are frequently used in arrays for gene expression studies to identify diseased cells due to over- or under-expression of certain genes, to follow the response of drug treatments, or to grade cancers), for genotyping of individuals, for the detection of single nucleotide polymorphisms, point mutations, and short tandem reports, or moreover for genome and transcriptome analyses in the quasi post-genomic sequencing era. Furthermore, due to some unique properties of DNA molecules, self-assembled layers of DNA are promising candidates in the field of molecular electronics.the main focus of these two volumes is on the immobilization chemistry, considering the various aspects of the immobilization process itself, since different types of nucleic acids, support materials, surface activation chemistries and patterning tools are of key concern.

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Imaging of Kidney Cancer

This is one of the first books to deal specifically with diagnostic imaging of the entire spectrum of kidney cancers. Both new and conventional imaging modalities are fully considered. In an introductory chapter, the histopathological classification of kidney cancers is presented and discussed. The following five chapters describe in great detail the abilities, advantages, and disadvantages of the various imaging modalities used in the diagnosis of kidney cancers and the assessment of disease extension. Subsequent chapters offer an exhaustive description of the radiological features of the different histological subtypes of kidney cancer, with radiological and histological illustrations and tables.

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Imaging Atlas of the Pelvic Floor and Anorectal Diseases

The goal of Imaging Atlas of the Pelvic Floor and Anorectal Diseases is to clearly and precisely present indications, techniques, limitations, sources of errors, and pitfalls of these imaging modalities.

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Image-Guided IMRT

Intensity-modulated radiation therapy (IMRT), one of the most important developments in radiation oncology in the past 25 years, involves technology to deliver radiation to tumors in the right location, quantity and time. Unavoidable irradiation of surrounding normal tissues is distributed so as to preserve their function. The achievements and future directions in the field are grouped in the three sections of the book, each suitable for supporting a teaching course.

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Image Analysis and Recognition ; 17th International Conference, ICIAR 2020, Póvoa de Varzim, Portugal, June 24–26, 2020, Proceedings, Part II

This two-volume set LNCS 12131 and LNCS 12132 constitutes the refereed proceedings of the 17th International Conference on Image Analysis and Recognition, ICIAR 2020, held in Póvoa de Varzim, Portugal, in June 2020. The 54 full papers presented together with 15 short papers were carefully reviewed and selected from 123 submissions. The papers are organized in the following topical sections: image processing and analysis; video analysis; computer vision; 3D computer vision; machine learning; medical image and analysis; analysis of histopathology images; diagnosis and screening of ophthalmic diseases; and grand challenge on automatic lung cancer patient management.

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Image Analysis and Recognition ; 17th International Conference, ICIAR 2020, Póvoa de Varzim, Portugal, June 24–26, 2020, Proceedings, Part I

This two-volume set LNCS 12131 and LNCS 12132 constitutes the refereed proceedings of the 17th International Conference on Image Analysis and Recognition, ICIAR 2020, held in Póvoa de Varzim, Portugal, in June 2020. The 54 full papers presented together with 15 short papers were carefully reviewed and selected from 123 submissions. The papers are organized in the following topical sections: image processing and analysis; video analysis; computer vision; 3D computer vision; machine learning; medical image and analysis; analysis of histopathology images; diagnosis and screening of ophthalmic diseases; and grand challenge on automatic lung cancer patient management.

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Il cancro e la ricerca del senso perduto = Cancer and the search for lost meaning

Cancer disease can be approached with the aim of killing diseased cells or with that of making them go backwards on the road that leads from a state of natural equilibrium to the disease. This book tells an original research by the author inspired by this biological vision of cancer, research that led to the production and use of anticancer products. Inevitably, the history of research slips into a vision of the world and of life that presents the features of a documented critique of the values and priorities that characterize the world in which we live. A profound and human book, which makes you think, which makes you hope.

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Ibuprofen : Discovery, development and therapeutics

Ibuprofen has become one of the foremost pain-relieving medications world-wide with its proven safety and efficacy in a wide variety of painful and inflammatory conditions. It has also been widely investigated for application in a variety of painful and non-pain inflammatory states including cancer and neurodegenerative conditions, reflecting the unique and novel properties of the drug that would never have been foreseen from knowledge of the properties when it was initially discovered.

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Hyperthermia In Cancer Treatment : A Primer

Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermia with radiation and chemotherapy and the biological and clinical effects of hyperthermia on cancerous and normal tissues. The volume’s 20 chapters are arranged in three principal parts: physical and methodological studies, biologic principles, and clinical studies.

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Hox Gene Expression

The study of Hox genes is crucial not only in exploring the enigma of homeosis but also in understanding normal development at the fundamental molecular level. "Hox Gene Expression" starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes- their evolution, structure, normal and abnormal function. Researchers and graduate students in Biology and Medicine will benefit from this integrated overview of Hox gene activities.

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Hormonal control of cell cycle

This volume reflects the proceedings of an International Workshop held in Paris in December 2006. The aim of the meeting was to undertake a high level of scholarly exchange between experts in cell biology, oncology and endocrinology interested in cell cycle control. The topics covered ranged from fundamental studies of DNA replication,chromosomal and nuclear function through growth factor control of endocrine tumor initiation and progression.

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