Human Challenge Studies in Endemic Settings : Ethical and Regulatory Issues
This book provides an extensive review of ethical and regulatory issues related to human infection challenge studies, with a particular focus on the expansion of this type of research into endemic settings and/or low- and middle-income countries (LMICs). Human challenge studies (HCS) involve the intentional infection of research participants, and this type of research is rapidly increasing in frequency worldwide
Human battle against obesity
Obesity is one of the most common preventable diseases and it is a medical condition in which excess fat has accumulated in the body, mostly in the subcutaneous tissues. Clinical obesity is considered to be present when a person has a body mass index of 30 or over. Obesity results from a chronic positive energy balance regulated by a complex interaction between endocrine tissues and the central nervous system, This activity reviews the pathophysiology of obesity, inflammatory markers secreted by excessive fat deposition in adipose tissue, and their effects on chronic diseases such as hypertension, diabetes, and dyslipidemia.
Human Aspects of Information Security and Assurance ; 14th IFIP WG 11.12 International Symposium, HAISA 2020, Mytilene, Lesbos, Greece, July 8–10, 2020, Proceedings
This book constitutes the proceedings of the 14th IFIP WG 11.12 International Symposium on Human Aspects of Information Security and Assurance, HAISA 2020, held in Mytilene, Lesbos, Greece, in July 2020.* The 27 full papers presented in this volume were carefully reviewed and selected from 43 submissions. They are organized in the following topical sections: privacy and COVID-19; awareness and training; social engineering; security behavior; education; end-user security; usable security; security policy; and attitudes and perceptions.
Human antibody therapeutics for viral disease
The articles in this volume are definitive and comprehensive reviews written by experts who have sought to define the principles of viral neutralization by human antibodies. They explore and anticipate the obstacles and opportunities that will be encountered as the power of human antibodies is harnessed to address the vast, un-met need for effective anti-viral therapeutics.
Human and Animal Relationships
Pathogenic fungi are widely distributed and can infect many organisms, particularly humans, but also other vertebrates and insects. Due to a growing number of fungal infections, there is an increasing need to understand the interaction of pathogenic fungi with their hosts. This second completely updated and revised edition of Volume VI of The Mycota consists of state of the art reviews written by experts in the field, covering three major areas of this rapidly developing field. In the first part the current understanding of pathogenic fungi and the physiological reactions relevant for the pathogen - host interaction are elucidated. The second part describes novel technologies for the identification of proteins, virulence factors and mechanisms central to the host - pathogen interaction. The third part deals with the characterization of the host response towards pathogenic fungi and addresses timely clinical aspects.
Hughes Syndrome : Antiphospholipid Syndrome
The second edition of Hughes Syndrome: Antiphospholipid Syndrome addresses the complete range of conditions produced by this common disorder which is also known as APS or "sticky blood" syndrome. APS is one of the main causes of strokes (40%), leg deep vein thrombosis, and recurrent miscarriages in women.
How to Organize Yourself : Simple Ways to Take Control, Save Time and Work More Efficiently
How to Organize Yourself will help you to dramatically improve the way you work. With great tips on how to determine your goals, prioritize your tasks and manage your time, it also includes practical advice on how to: focus on the things that produce results; overcome distractions; build positive work habits; avoid information overload and make effective use of technology.
How to Manage Projects : Essential Project Management Skills to Deliver On-time, On-budget Results
Provides a complete, jargon-free introduction to the principles and practices of project management, along with practical tools and checklists to use in real life / Is part of the bestselling Creating Success series, which has sold over 1.5 million copies and contains practical advice on essential and value-adding work skills to help you develop your career / Features practical, exercises, templates tools and checklists to use in real life
How to Improve the Results of Peripheral Nerve Surgery
All over the world research is going on to improve the outcome of the treatment of peripheral nerve lesions. Questions over questions arise. Is the autologeous nerve grafting still the golden standard in bridging defects? Have alternative techniques to overcome defects reached a level to replace autografting? To which length are they effective? What is the role of allografting? Are there still indications for vascularized nerve grafts? What can be expected from end to side coaptation? Does it exist at all? Under what conditions useful recoveries can be achieved? Are there new developments in physical medicine and physiotherapy? Can the quality of recovery be influenced by surgery on muscles to provide a better equilibrium of forces? To what extent cerebral plasticity may be exploited to improve functional results? The contributions in this book give answers to all of these questions.
How to Code .NET : Tips and Tricks for Coding .NET 1.1 and .NET 2.0 Applications Effectively
How to Code .NET: Tips and Tricks for Coding .NET 1.1 and .NET 2.0 Applications Effectively provides solutions to certain problems. That is, specific problems. This book provides detailed, authoritative explanations of good .NET coding techniques.
How to Build Your Brand : Implementing a Proven and Effective Process
Develop "big picture" insight that inspires big brand ideas Use imagery to understand the fundamental human values that give our life meaning as well as learn about the feelings that reveal our hopes and dreams. Develop highly motivating brand concepts that link to our values and aspirations. Create the tactical roadmap to implement the concepts.
How to Build a Modern Tontine : Algorithms, Scripts and Tips
This book introduces the modern tontine and its applications in retirement and decumulation. Personal financial management in the later stages of life presents unique challenges, and renowned retirement planning expert Dr. Milevsky proposes the modern tontine as a solution. With the goal of guiding professionals and retirees in more efficient decumulation, the book demonstrates how to build a modern tontine. It is technically oriented, employing a cookbook format, featuring R code, and examining retirement planning through a statistical lens.
How to be an Even Better Manager : A Complete A-Z of Proven Techniques and Essential Skills
For current and aspiring managers alike, this bestselling handbook from expert author Michael Armstrong provides a whistle-stop tour of the skills and techniques you need to succeed. With a focus on practical application, you will be guided through four crucial areas of management: Managing people / Management activities and processes / Management personal skills / Business and financial skills
How structures work : Design and behaviour from bridges to buildings ; 2nd ed.
How the building behaves when subjected to various forces – the weight of the materials used to build it, the weight of the occupants or the traffic it carries, the force of the wind etc – is fundamental to its stability. The alliance between architecture and structural engineering is therefore critical to the successful design and completion of the buildings and infrastructure that surrounds us. Yet structure is often cloaked in mathematics which many architects and surveyors find difficult to understand.
How does the Galaxy Work? : A Galactic Tertulia with Don Cox and Ron Reynolds
Presents a multi-disciplinary approach to the physical mechanisms which structure the shape, evolution and fate of the Galaxy. It contains 4 panel sessions (the recording transcripts of the galactic 'tertulias'), an introductory historical overview on the Galaxy research, 17 reviews, and the proceedings of more than 50 oral and poster contributions. This book is not a new edition of a previous volume but it is in some way related to the book "The Formation of the Milky Way" (1995; Cambridge University Press), which contains the proceedings of the first IAA-IAC-University of Pisa meeting, held in Granada ten years ago, on the formation of the Milky Way, (see Shore's introduction). Where many other books focus their attention on singular galactic components or specific driving forces, this title provides a wide overview on the gaseous and stellar components and on the physical mechanisms which maintain the dynamical equilibrium of such a complex system as the Galaxy. The book, intended for graduate students and researchers, provides a valuable overview on the different physical mechanisms which drive the galactic gas-stars feedback.
How Data Quality Affects our Understanding of the Earnings Distribution
This book demonstrates how data quality issues affect all surveys and proposes methods that can be utilised to deal with the observable components of survey error in a statistically sound manner. This book begins by profiling the post-Apartheid period in South Africa's history when the sampling frame and survey methodology for household surveys was undergoing periodic changes due to the changing geopolitical landscape in the country. This book profiles how different components of error had disproportionate magnitudes in different survey years, including coverage error, sampling error, nonresponse error, measurement error, processing error and adjustment error.
How and what marketing algorithms think
Argues that the apparent omnipotence of algorithms today is not what it seems, particularly, in marketing, where they actually offer less than they could. Considering the reasons behind this, it also notes that Big Data has relaunched a kind of data glorification and automated procedures that, culturally, marketing has already recognized and overcome at least once.
Housing Market Dynamics in Africa
Utilizes new data to thoroughly analyze the main factors currently shaping the African housing market. Some of these factors include the supply and demand for housing finance, land tenure security issues, construction cost conundrum, infrastructure provision, and low-cost housing alternatives. Through detailed analysis, the authors investigate the political economy surrounding the continent’s housing market and the constraints that behind-the-scenes policy makers need to address in their attempts to provide affordable housing for the majority in need. With Africa’s urban population growing rapidly, this study highlights how broad demographic shifts and rapid urbanization are placing enormous pressure on the limited infrastructure in many cities and stretching the economic and social fabric of municipalities to their breaking point. But beyond providing a snapshot of the present conditions of the African housing market, the book offers recommendations and actionable measures for policy makers and other stakeholders on how best to provide affordable housing and alleviate Africa’s housing deficit.
Hot Topics in Infection and Immunity in Children II
Hot Topics in Infection and Immunity II provides a current view from leading experts concerning the hottest topics of concern to clinicians caring for children with infections. The book brings together a collection of manuscripts from a faculty of authors of international standing who contributed to a course in Paediatric Infection and Immunity in Oxford, UK in June 2004.
Hot house : Global climate change and the human condition
Global warming is extremely complex because it deals with so many different characteristics of the Earth and their complex interactions. It is addressed by almost all sciences including many aspects of geosciences, atmospheric, the biological sciences, and even astronomy. It has recently become the concern of other diverse disciplines such as economics, agriculture, demographics and population statistics, medicine, engineering, and political science. This book attempts to address these complex interactions, integrate them, and derive meaningful conclusions and possible solutions.



















