الصفحة 57
الصفحة 57
A Study about Prevalence of Thalassemia Complications in Syrian Patients
Inherited haemoglobin disorders, including thalassemia and sickle-cell disease, are the most common monogenic diseases worldwide. Several clinical forms of α-thalassemia and β-thalassemia, including the co-inheritance of β-thalassemia with haemoglobin E resulting in haemoglobin E/β-thalassemia, have been described. The disease hallmarks include imbalance in the α/β-globin chain ratio, ineffective erythropoiesis, chronic hemolytic anemia, compensatory hemopoietin expansion, hypercoagulability, and increased intestinal iron absorption. The complications of iron overload, arising from transfusions that represent the basis of disease management in most patients with severe thalassemia. The mature Hb molecule is a tetramer composed of 2 a-globin and 2 b-globin polypeptides, which assemble, along with a heme prosthetic group, to form the complete molecule.
A Stakeholder Rationale for Risk Management : Implications for Corporate Finance Decisions
Ordinarily, only the interests of shareholders, debtholders, and corporate management are taken into account when analyzing corporate financial decisions while the interests of non-financial stakeholders are often neglected. Gregor Gossy develops a so-called stakeholder rationale for risk management arguing that firms which are more dependent on implicit claims from their non-financial stakeholders, such as customers, suppliers, and employees, prefer conservative financial policies. In order to perform panel data analyses of the determinants of corporate financial decisions, the author uses data from Austrian and German industrial companies. He shows that variables for a firm’s most important non-financial stakeholders explain the firm’s capital structure and cash holding decisions. His findings suggest that a firm’s choice of accounting standards have a moderating effect on the determinants of corporate finance decisions.
A Software-Defined GPS and Galileo Receiver : A Single-Frequency Approach
Satellite navigation receivers are used to receive, process, and decode space-based navigation signals, such as those provided by the GPS constellation of satellites. There is an increasing need for a unified open platform that will enable enhanced receiver development and design, as well as cost-effective testing procedures for various applications. This book provide hands-on exploration of new technologies in this rapidly growing field. One of the unique features of the work is the interactive approach used, giving readers the ability to construct their own Global Navigation Satellite Systems (GNSS) receivers. To construct such a reconfigurable receiver with a wide range of applications, the authors discuss receiver architecture based on software-defined radio (SDR) techniques. The presentation unfolds in a systematic, user-friendly style and goes from the basics to cutting-edge research.
A Risk-Benefit Perspective on Early Customer Integration
Customer integration in the early innovation phase has been considered the method of choice in theory and practice. Growing experience with the concept has shown unexpected side effects that may even outweigh its recognized advantages. Therefore, management needs to be able to assess in advance whether the involvement of customers will add overall value to each particular innovation project. To support but not to replace the final managerial decision, a mathematical formula is developed. It can be applied to all kinds of process structures, takes into account the risks and benefits contingent on a company's situation as well as risk-reducing and benefit-increasing measures and translates them into numerical values. The resulting figure indicates the prospective value of customer integration in a specific project.
A practical guide on behaviour change support for self-managing chronic disease
Developed under the auspices of the Train4Health project, funded by the Erasmus+ program of the European Union, the book contains six chapters written by international contributors from different disciplines. Chapter one introduces the competencies necessary for delivering effective behavior change support, based on an established program of work, and related learning outcomes. The four following chapters describe how these competencies can be acquired, focusing on concepts and theories, assessing self-management behaviors, implementing change strategies and person-centered communication, using a practical approach.
A Platform-Centric Approach to System-on-Chip (SOC) Design
The book proposes a new methodology for realizing platform-centric design of complex systems, and presents a detailed plan for its implementation. The proposed plan allows component vendors, system integrators and product developers to collaborate effectively and efficiently to create complex products within budget and schedule constraints.
A Pan-Chromatic View of Clusters of Galaxies and the Large-Scale Structure
The reviews presented in this volume cover a wide-range of cluster of galaxies topics like the physics of the ICM gas, the internal cluster dynamics, the detection of clusters using different observational techniques, the great advances in analytical or numerical modeling of clusters, weak and strong lensing effects, the large scale structure as traced by clusters, the cosmological significance of clusters as well as the formation and evolution of clusters within the new cosmological paradigm.
A new deal for an effective European research policy : The design and impacts of the 7th Framework programme
It underlines an important truth: that science has always advanced most rapidly when it is a collective endeavour, with a strong circulation of knowledge.This book will show how the new Framework Programme was put together and explain why it took the shape it did. It will also set out its potential impacts and the conditions necessary for it to be a success.
A History of Interior Design ; 5th Ed
Interior design describes the process by which an interior space is made into an effective setting for whatever range of human activities are to take place there. Much like the history of art, the history of interior design encompasses numerous styles, movements, and the influence of international, political, and social developments. A basic understanding of this history is important to students taking survey courses, professional designers looking to the past for inspiration, and for those interested in antiques, furniture design, and the general evolution of the spaces where we work and live
A History of Atmospheric CO2 and Its Effects on Plants, Animals, and Ecosystems
The authors address the future role of atmospheric CO2 and its likely effects on ecosystems. This book incorporates the advances of various earth science, environmental, and ecological fields into an overall account of global change and the changing dynamics of life on Earth.
A Dictionary of World History
This wide-ranging dictionary contains a wealth of information on all aspects of history, from prehistory right up to the present day. Accessible, clear, and concise entries include biographies of key figures in world history (living and dead), separate entries for every country in the world (summarising key historical events), and in-depth entries on religious and political movements, international organizations, and major conflicts and events and their after-effects.
A Clinician's guide to systemic effects of periodontal diseases
Serves as an ideal, easy-to-use reference for the practicing health professional. It summarizes the latest research on the systemic effects of periodontal diseases, discusses how the results of this research will impact on clinical practice, and aims to help the clinician to answer questions that may be posed by patients, medical colleagues, and the media.
A buyers and users guide to astronomical telescopes & binoculars
Provides an extensive overview of astronomical binoculars and telescopes. It includes detailed up-to-date information on sources, selection and use of virtually every major type, brand, and model of such instruments on today’s market. A Buyer’s & User’s Guide to Astronomical Telescopes and Binoculars is written for amateur astronomers and would-be amateur astronomers. Anyone planning to purchase binoculars or telescopes for astronomy – whether as a first instrument or as an upgrade to the next level – will find this book a treasure-trove of information and advice. But that is just the first part of the book. The second part is crammed with hints and tips on using astronomical telescopes or binoculars – in effect, how to get the best possible results from your purchase.
70 Years of Levothyroxine
Presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy. It also describes the influence of levothyroxine on heart, bone and in cancer. When it was first synthesized in 1949, levothyroxine represented a significant advance in the treatment of hypothyroidism, providing a safe and effective treatment option for millions of hypothyroid patients around the globe. This synthetic form of thyroxine is now one of the most prescribed drugs in the world. Levothyroxine was first introduced by Merck KGaA,Darmstadt, Germany, in 1972, and since then the company has remained actively engaged in research on this mainstay of hypothyroidism treatment.
501 Math Word Problems
Contains only word problems - the kinds you encounter at school and on high stakes tests. Gaining familiarity with this specific question type is a proven technique for increasing test scores. The Skill Builder in Focus method provides the targeted practice on these questions necessary to attain higher scores. Questions are divided into six chapters: algebra, geometry, fractions, percents, decimals, and miscellaneous math. Within each chapter, questions move from easy to advanced, giving test-takers the opportunity to gain confidence in each math area. Each chapter contains questions, answers, and detailed explanations to reinforce learning and understanding. Diagrams and useful terminology help clarify math rules for effective studying and retention.
3rd Kuala Lumpur International Conference on Biomedical Engineering 2006 ; Biomed 2006, 11-14 December 2006, Kuala Lumpur, Malaysia
The Kuala Lumpur International Conference on Biomedical Engineering (Biomed 2006) was held from 11 to 14 December 2006 at the Palace of the Golden Horses, Kuala Lumpur, Malaysia. This international conference was jointly organised by the Department of Biomedical Engineering, University of Malaya, Malaysia; Department of Biomedical Engineering, Inje University, Korea; and Malaysian Society of Medical and Biological Engineering. The papers presented at Biomed 2006 cover the following areas: artificial intelligence, biological effects of non-ionising electromagnetic fields, biomaterials, biomechanics, biomedical sensors, biomedical signal analysis, biotechnology, clinical engineering, human performance engineering, imaging, medical informatics, medical instruments and devices, physiological modelling, simulation, and control, prostheses and artificial organs, regulations and organisations, rehabilitation engineering, telemedicine, tissue engineering, and virtual reality in medicine.
3D printing of pharmaceutical and drug delivery devices progress from bench to bedside
Discover the latest, fast-developing technology to help move towards more cost-effective, small-batch, decentralized manufacturing of personalized systems . 3D printing has revolutionized manufacturing. Its precision and flexibility have enabled the large-scale production of materials and devices too complex for conventional industrial manufacturing. This has been particularly revolutionary in the field of pharmaceutical production, where 3D printing is being integrated into the manufacture of both drugs and drug delivery devices. It has never been more important for industry professionals to understand this form of production.
35th Hemophilia Symposium Hamburg 2004 ; epidemiology ; risk of infections and inhibitors in hemophilia ; chronic lic synovitis and long-term results of orthopedic treatment ; laboratory diagnostics : coagulation factors ; inhibitors, monitoring ; pediatric hemostaseology ; Free Lectures
Motion analysis as introduced 2 years ago on a national basis effectively identifies individual functional disorders and provides a means for describing them on the basis of a score. Individual therapy planning is possible. More treatment tends to produce better function scores and thus helps to lower the strain on the joint.
150 Best Terrace and Balcony Ideas
The ultimate resource for innovative terrace, roof garden, patio, and balcony design ideas for outdoor spaces of all shapes and sizes. Featured inside this lavish guidebook are 150 never-before-shared tips and techniques provided by internationally renowned architects and designers, along with full-color photographs and diagrams of sixty-five uniquely beautiful projects from around the world. The design ideas reveal how to create exterior spaces that are clean, modern, and comfortable, as well as how to use cutting-edge materials that are practical, cost-effective, and environmentally friendly. Best of all, the design ideas featured inside are easy to follow and can be tailored to the unique tastes and needs of individual homeowners.
150 Best New Bathroom Ideas
Showcasing an extensive collection of designs and style, captured in stunning full-color photos, 150 Best New Bathroom Ideas provides an in-depth review of outstanding bathroom designs from internationally renowned architects and designers. Here are the most attractive, functional, and cost-effective bathroom concepts from around the world. Practical yet beautiful and stylish, 150 Best New Bathroom Ideas includes innovative ideas for lighting, floor, wall, and window treatments, and for showers, toilets, sinks, and bathtubs. An essential design and decorating reference, 150 Best New Bathroom Ideas covers the diversity of current trends and is an inspirational source for homeowners, designers, interior decorators, and architects.
