الصفحة 55
الصفحة 55
High Density Lipoproteins : From Biological Understanding to Clinical Exploitation
In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation.
High Confidence Software Reuse in Large Systems ; 10th International Conference on Software Reuse, ICSR 2008, Beijing, China, May 25-29, 2008 Proceedings
This book constitutes the refereed proceedings of the 10th International Conference on Software Reuse, ICSR 2008, held in Beijing, China, in May 2008.The 40 revised full papers presented together with 5 workshop summaries and 5 tutorials were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on architecture and reuse approaches, high confidence and reuse, component selection and reuse repository, product line, domain models and analysis, service oriented environment, components and services, reuse approaches and frameworks, as well as reuse approaches and methods.
High Availability and Disaster Recovery : Concepts, Design, Implementation
Companies and other organizations depend more than ever on the availability of their Information Technology, and most mission critical business processes are IT-based processes. Business continuity is the ability to do business under any circumstances and is an essential requirement modern companies are facing. High availability and disaster recovery are contributions of the IT to fulfill this requirement. And companies will be confronted with such demands to an even greater extent in the future, since their credit ratings will be lower without such precautions. Both, high availability and disaster recovery, are realized by redundant systems. Redundancy can and should be implemented on different abstraction levels: from the hardware, the operating system and middleware components up to the backup computing center in case of a disaster. This book presents requirements, concepts, and realizations of redundant systems on all abstraction levels, and all given examples refer to UNIX and Linux systems.
Hierarchy in Natural and Social Sciences
This book reviews ancient and modern representations and explanations of hierarchies, and compares their relevance in a variety of fields, such as language, societies, cities, and living species. It throws light on concepts and models such as scaling laws, fractals and self-organisation that are fundamental in the dynamics and morphology of complex systems.This book addresses a wide audience of biologists and social scientists, as well as managers and executives in a variety of institutions.
Hiérarchie de modèles en optique quantique: De Maxwell-Bloch à Schrödinger non-linéaire
The book under review appears to be relevant in this respect since it cross-fertilizes such a fundamental field of research in physics in two important ways.
Hierarchical Bayesian Optimization Algorithm : Toward a New Generation of Evolutionary Algorithms
This book provides a framework for the design of competent optimization techniques by combining advanced evolutionary algorithms with state-of-the-art machine learning techniques. The book focuses on two algorithms that replace traditional variation operators of evolutionary algorithms by learning and sampling Bayesian networks: the Bayesian optimization algorithm (BOA) and the hierarchical BOA (hBOA). BOA and hBOA are theoretically and empirically shown to provide robust and scalable solution for broad classes of nearly decomposable and hierarchical problems. A theoretical model is developed that estimates the scalability and adequate parameter settings for BOA and hBOA. The performance of BOA and hBOA is analyzed on a number of artificial problems of bounded difficulty designed to test BOA and hBOA on the boundary of their design envelope.
Hidden Markov Models in Finance
A number of methodologies have been employed to provide decision making solutions to a whole assortment of financial problems in today's globalized markets. Hidden Markov Models in Finance by Mamon and Elliott will be the first systematic application of these methods to some special kinds of financial problems; namely, pricing options and variance swaps, valuation of life insurance policies, interest rate theory, credit risk modeling, risk management, analysis of future demand and inventory level, testing foreign exchange rate hypothesis, and early warning systems for currency crises.
Heterogeneous Objects Modelling and Applications : Collection of Papers on Foundations and Practice
Heterogeneous object modelling is a new and quickly developing research area. This book is one of the first attempts to systematically cover the most relevant themes and problems of this new and challenging subject area. It is a collection of invited papers and papers co-authored by the editors. Each chapter presents either new research results or a survey on the following topics:Formal models and abstractions of heterogeneous objects including geometric, topological, discrete and continuous models, operations forming special algebras and conversions between different model types.
Heterogeneous Enantioselective Hydrogenation : Theory and Practice
The book looks at the first relatively ineffective catalysts right through to modern highly effective enantioselective catalytic systems, comparable in their efficiency to chiral metal complexes and enzymatic systems. The book begins with a summary of the first work on heterogeneous metal catalysts, which showed only the principal possibilities of enantioselective reactions. The book then elaborates on metal catalysts which have enantioselectivities close to 100%. Finally, the book describes the practical utilization of chiral catalytic systems in processes of hydrogenation. The a - and b -hydroxy carboxylic acid esters produced are precursors for manufacturing many synthones used for medicines as well as for monomers used for biodegradable polyesters, both of which have important practical applications. The book summarizes more than 800 scientific papers in the field of enantioselective catalytic hydrogenation reactions, mainly those using heterogeneous metal catalysts. It provides detailed explanations of special techniques for the preparation of effective dissymmetric catalysts which provide highly efficient catalytic systems.
Heterogeneity, high performance computing, self-organization and the cloud
Addresses the most recent developments in cloud computing such as HPC in the Cloud, heterogeneous cloud, self-organising and self-management, and discusses the business implications of cloud computing adoption. Establishing the need for a new architecture for cloud computing, it discusses a novel cloud management and delivery architecture based on the principles of self-organisation and self-management. This focus shifts the deployment and optimisation effort from the consumer to the software stack running on the cloud infrastructure. It also outlines validation challenges and introduces a novel generalised extensible simulation framework to illustrate the effectiveness, performance and scalability of self-organising and self-managing delivery models on hyperscale cloud infrastructures. It concludes with a number of potential use cases for self-organising, self-managing clouds and the impact on those businesses.
Heterogeneity in statistical genetics : How to assess, address, and account for mixtures in association studies
Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.
Heterocycles from Carbohydrate Precursors
This book is a volume in the series Topics in Heterocyclic Chemistry.Itc- ers the key methods used for designing synthetic approaches to heterocycles from carbohydrates and the value and scope of these methods. Carbohydrates are widely distributed in nature and constitute the largest part of renewable biomasses. Moreover, many carbohydrates and their derivatives are comm- cially available at relatively cheap prices. Consequently their utilization is highly encouraged and economically they are of great signifcance. Moreover, carbohydrates are highly functionalized compounds that can be readily deritized and/or cyclized to provide heterocyclic compounds. This book provides a modern account and an up-to-date description of the advancement in the synthesis of diverse heterocycles from carbohydrates. Carbohydrates can be considered as a source of chiral centers in addition to the variable modifcation thereof.
Hermeneutics and Hindu Thought : Toward a Fusion of Horizons
The emergence of Hinduism as a field of study in the Western academia coincides with the development of modern hermeneutics. Despite this coemergence, and the rich possibilities inherent in a dialectical encounter between the theories of modern and pre-modern hermeneutics and those of Hindu hermeneutical traditions, this potential has not been tapped within the boundaries of religious studies. This volume sets out to initiate such an interface.Some essays in this volume, such as those by Shrinivas Tilak, Sharada Sugirtharajah, and Purushottama Bilimoria examine the impact of Western hermeneutics on the Indian religious landscape.
Heritage building conservation : Sustainable and digital modelling
Covers: The technology used to digitally document heritage buildings, including LIDAR, photogrammetry, Heritage Building Information Modelling (HBIM), and Virtual Reality (VR) technologies Introducing a Maintainability Index of Heritage Buildings (MIHB) to support the decision-making and prioritization process for the maintenance of heritage buildings The adaptive reuse of heritage buildings Modelling embodied and operational energy performance Using Chatbot and Blockchain technology to support the management and preservation of heritage buildings Ultimately, this book presents a useful tool for use in heritage management and highlights how the reusability of heritage buildings is critical to the creation and survival of sustainable communities.
Herbal pharmacopeia : Nanotechnology and advancing drug
Explores the intersection between traditional herbal medicine and cutting-edge nanotechnology. The chapters introduce modern techniques used in herbal extraction and analysis. The principles of drug discovery from plants are discussed, with a focus on the identification and development of bioactive compounds that have therapeutic potential. It discusses the pharmacological properties, biotechnological approaches in drug development, and challenges in the formulation and standardization of herbal medicines. Emerging trends and applications of nanotechnology in herbal pharmacotherapy, such as nanoparticle synthesis, enhanced bioavailability using nanocarriers, safety assessments, novel and targeted delivery systems, and regulatory considerations, are thoroughly discussed. Additionally, it includes a comparative analysis of traditional and nano-formulated approaches and their implementation in clinical settings. Towards the end, the book reviews the regulatory considerations for herbal products and future perspectives in herbal pharmacopeia. This book is intended for researchers, clinicians, and professionals in herbal medicine, pharmacology, and nanotechnology.
Herbal medicine in India : Indigenous knowledge, practice, innovation and its value
Covers Indian herbal medicines, health products, pharmaceuticals, nutraceuticals, and cosmetics. Highlights the status quo and future prospects of traditional medicine in India / Provides information on drug discovery, ethnobotany, isolation of phytochemicals, importance of herbal nutraceuticals, etc. / Covers innovation, validation and IPR issues related to Indian traditional medicine
Hemodynamical Flows : Modeling, Analysis and Simulation
This book surveys research results on the physical and mathematical modeling, as well as the numerical simulation of complex fluid and structural mechanical processes occurring in the human blood circulation system. Topics treated include continuum mechanical description; choice of suitable liquid and wall models; mathematical analysis of coupled models; numerical methods for flow simulation; parameter identification and model calibration; fluid-solid interaction; mathematical analysis of piping systems; particle transport in channels and pipes; artificial boundary conditions, and many more.
Hedonic Methods in Housing Markets : Pricing Environmental Amenities and Segregation
Cities are growing worldwide and their sprawl is increasingly challenged for its pressure on open spaces and environmental quality. Economic arguments can help to decide about the trade-off between preserving environmental quality and developing housing and business surfaces, provided the benefits of environmental quality are adequately quantified. To this end, this book focuses on the use and advancement of the "hedonic approach", an economic valuation technique that analyses and quantifies the sources of rent and property price differentials. Starting from theoretical foundations, the hedonic approach is applied to the valuation of natural land use preservation and noise abatement measures, as well as to residential segregation and discrimination, extending the analysis to the role of the buyers' and sellers' identity on housing market prices and to the issue of environmental justice.
Hedgehog-Gli Signaling in Human Disease
Hedgehog-GLI Signaling in Human Disease represents the first compilation of up-to-date reviews by top-level scientists in this important field of research. The chapters cover a wide spectrum of related interests, from the molecular bases of morphogen function, to human genetics to cancer research. The aim of the book is to disseminate information on this exciting field, to allow students, scientists and the public in general to gain access current information from research leaders and to provide a book that encompasses different aspects of research showing the fusion of basic research in model systems and medicine. This is a timely primer on how a system of cell communication, Hedgehog-GLI signaling, plays a critical role in human disease and thus provides the background for the development of novel and rational therapies.
Heavy-Tail Phenomena : Probabilistic and Statistical Modeling
This comprehensive text gives an interesting and useful blend of the mathematical, probabilistic and statistical tools used in heavy-tail analysis. Heavy tails are characteristic of phenomena where there is a significant probability of a single huge value impacting system behavior. Record-breaking insurance losses, financial returns, sizes of files stored on a server, transmission rates of files are all examples of heavy-tailed phenomena.
