الصفحة 55
الصفحة 55
Advances in pharmacokinetics and pharmacodynamics
Provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.
Advances in Meshfree Techniques
In recent years meshless/meshfree methods have gained a considerable attention in engineering and applied mathematics. The variety of problems that are now being addressed by these techniques continues to expand and the quality of the results obtained demonstrates the effectiveness of many of the methods currently available. The book presents a significant sample of the state of the art in the field with methods that have reached a certain level of maturity while also addressing many open issues.The book collects extended original contributions presented at the first ECCOMAS Conference on Meshless Methods held in 2005 in Lisbon. The list of contributors reveals a mix of highly distinguished authors as well as quite young but very active and promising researchers, thus giving the reader an interesting and updated view of different mesh reduction methods and its range of applications. The material presented is appropriate for researchers, engineers, physicists, applied mathematicians and graduate students interested in this active research area.
Advances in Mechanics of Materials for Environmental and Civil Engineering
Deals with both mathematical modeling and experimental studies related to systems relevant for various civil engineering fields. The book addresses several key topics, including artificial intelligence applied to the control and monitoring of construction site personnel, finite element models for endplate beam-to-column connections under various load conditions, random functionally graded micropolar beams, and many others. The book explores the design and study of microstructures aimed at increasing the toughness and durability of novel materials in building and construction, based also on the re-utilization of residues and wastes of metallurgical industry produces.
Advances in mathematical economics ; Vol. 9
A lot of economic problems can formulated as constrained optimizations and equilibration of their solutions. Various mathematical theories have been supplying economists with indispensable machineries for these problems arising in economic theory. Conversely, mathematicians have been stimulated by various mathematical difficulties raised by economic theories. The series is designed to bring together those mathematicians who were seriously interested in getting new challenging stimuli from economic theories with those economists who are seeking for effective mathematical tools for their researchers.
Advances in mathematical economics ; Vol. 8
The series is designed to bring together those mathematicians who were seriously interested in getting new challenging stimuli from economic theories with those economists who are seeking for effective mathematical tools for their researchers.
Advances in mathematical economics ; Vol. 11
A lot of economic problems can formulated as constrained optimizations and equilibration of their solutions. Various mathematical theories have been supplying economists with indispensable machineries for these problems arising in economic theory. Conversely, mathematicians have been stimulated by various mathematical difficulties raised by economic theories. The series is designed to bring together those mathematicians who were seriously interested in getting new challenging stimuli from economic theories with those economists who are seeking for effective mathematical tools for their researchers.
Advances in mathematical economics ; Vol. 10
The series is designed to bring together those mathematicians who were seriously interested in getting new challenging stimuli from economic theories with those economists who are seeking for effective mathematical tools for their researchers.
Advances in Land Remote Sensing : System, Modeling, Inversion and Application
It systematically summarizes the past achievements and identifies the frontier issues as the research agenda for the near future. It covers all aspects of land remote sensing, from sensor systems, physical modeling, inversion algorithms, to various applications. The papers on remote sensing system evaluate the capabilities of different sensor systems for estimating key land surface variables and how they can best be improved and integrated effectively in the future.
Advances in Intelligent Web Mastering ; Proceedings of the 5th Atlantic Web Intelligence Conference – WIC’2007, Fontainebleau, France, June 25 – 27, 2007
Mastering and effective exploration of the web environment needs new ideas, adaptation of known methods as well as application of sophisticated and robust technical implementations. Among new research directions present in relation to Web applications, a remarkable place is occupied by intelligent methods defining the topic of soft computing. This edited book includes reports from the front of diverse fields of the Web: application of artificial intelligence, design, information retrieval and interpretation, user profiling, security, engineering, etc. The material has been presented at the 5th Atlantic Web Intelligence Conference – AWIC’2007 held in Fontainbleau (France) and organized by Esigetel, Technical University of Lodz, and Polish Academy of Sciences.
Advances in Fracture Research : Honour and plenary lectures presented at the 11th International Conference on Fracture (ICF11), held in Turin, Italy, on March 20-25, 2005
Biological materials are bottom-up designed systems formed from billions of years of natural evolution. In the long course of Darwinian competition for survival, nature has evolved a huge variety of hierarchical and multifunctional systems from nucleic acids, proteins, cells, tissues, organs, organisms, animal communities to ecological s- tems. Multilevel hierarchy a rule of nature. The complexities of biology provide an opportunity to study the basic principles of hierarchical and multifunctional s- tems design, a subject of potential interest not only to biomedical and life sciences, but also to nanosciences and nanotechnology. Systematic studies of how hierarchical structures in biology are related to their functions and properties can lead to better understanding of the effects of aging, diseases and drugs on tissues and organs, and may help developing a scienti?c basis for tissue engineering to improve the standard of living.
Advances in Evolutionary Algorithms : Theory, Design and Practice
The goal of this book is to provide effective optimization algorithms for solving a broad class of problems quickly, accurately, and reliably by employing evolutionary mechanisms. In this regard, five significant issues have been investigated: Bridging the gap between theory and practice of GEAs, thereby providing practical design guidelines. Demonstrating the practical use of the suggested road map. Offering a useful tool to significantly enhance the exploratory power in time-constrained and memory-limited applications. Providing a class of promising procedures that are capable of scalably solving hard problems in the continuous domain. Opening an important track for multiobjective GEA research that relies on decomposition principle.
Advances in Electromagnetic Fields in Living Systems ; Vol.4
Advances in Electromagnetic Fields in Living Systems , Volume 4 begins with fetal magnetocardiography (fMCG), a noninvasive method of detecting components of the magnetic field produced by the electrical activity of the fetal heart. FMCG is experiencing steady growth, and is expected to gain influence in diagnosing certain congenital fetal heart defects while at the same time providing optimal care for patients. FMCG provides a distinct signal, free of maternal cardiac interference, which can be detected throughout the last half of pregnancy.
Advances in Automatic Differentiation
Covers advances in automatic differentiation theory and practice. Computer scientists and mathematicians will learn about recent developments in automatic differentiation theory as well as mechanisms for the construction of robust and powerful automatic differentiation tools. Computational scientists and engineers will benefit from the discussion of various applications, which provide insight into effective strategies for using automatic differentiation for inverse problems and design optimization.
Advanced Web and Network Technologies, and Applications ; APWeb 2006 International Workshops : XRA, IWSN, MEGA, and ICSE, Harbin, China, January 16-18, 2006, Proceedings
The QOS evaluating model for computational grid nodes put forward can help greatly improving the self-adaptability of resource management and accelerating the appli- tion and development of Computational Grid. Now this model has been applied in NPU Campus Computational Grid. And the good effect brought by it has effectively proved its function. References 1. Foster, I. and C. Kesselman, eds. The Grid: Blueprint for a New Computing Infrastructure. Morgan Kaufmann, 1999. 2. Liu Liang, Zhou Xing-she, and Gu Jian-hua: A Multi-Agent System for Grid Computing. The Second International Conference on Active Media Technology, 2003 3. Yao Wang, Julita Vassileva: Trust and Reputation Model in Peer-to-Peer Networks. Farag Azzedin and Muthucumaru Maheswaran: Integrating Trust into Grid Resource M- agement Systems.
Advanced Planning in Fresh Food Industries: Integrating Shelf Life into Production Planning
Production planning in fresh food industries is a challenging task. Although modern Advanced Planning and Scheduling (APS) systems could provide significant support, APS implementation numbers in these industries remain low. Therefore, based on an in-depth analysis of three sample fresh food industries (dairy, fresh and processed meat), the author evaluates what APS systems should offer in order to effectively support production planning and how the leading systems currently handle the most distinguishing characteristic of fresh food industries, the short product shelf life. Starting from the identified weaknesses, customized software solutions for each of the sample industries are proposed that allow to optimize the production of fresh foods with respect to shelf life.
Advanced Peripheral Nerve Surgery and Minimal Invasive Spinal Surgery
A summary of the most recent and effective techniques for treating difficult functional problems and painful situations using minimally invasive spinal surgery techniques. Including an up-to-date review of the physiopathology of the diseases.
Advanced Issue Resolution in Safety Pharmacology
Advanced Issue Resolution in Safety Pharmacology not only discusses unique issues that may emerge during the development of new medicines, but also provides detailed insights on how to resolve them. The book employs a valuable strategy that integrates preclinical findings with the clinical resolution of those findings. In addition, it introduces key interdisciplinary topics in an accessible and systematic format. Edited and written by leaders in the field of safety pharmacology, this book considerably advances the discussion on issue resolution topics, thus raising them to the next level of importance by providing scientists with an indispensable resource on solving safety issues.
AdvancED Flex 3
Divided into three parts. The first part discusses the architectural and design aspects of Flex 3 application development. It explains the internals of a Flex 3 application and advocates a few best practices to fine-tune your application to ensure maximum performance. It includes tutorials on creating custom components, data binding, and creating AIR-powered desktop applications. The second part concentrates on effectively integrating Flex 3 with server- and client-side technologies. Techniques for integration with Java and PHP are covered in detail, and content covering interaction with client-side technologies is also included. After reading the chapter on JavaScript integration, you will be ready to create applications that can use Ajax and Flex 3 together. The third and final part of the book is a unique and eclectic mix of some advanced topics like mash-ups, collaborative applications, 3D rendering, highly interactive visualization, and audio and video streaming.
AdvancED Flash Interface Design
Flash allows users to create some amazing interactive interfaces to interact with rich Internet applications, e-learning systems, and simple web sites. In this book, two of the most talented Flash designers in the world will show you how to use them effectively to create breathtaking visuals for your Flash web sites. You'll also learn how to take advantage of Flash's powerful built-in vector-based drawing tools.
Advanced Experimental Methods For Noise Research in Nanoscale Electronic Devices
The approach described is to create methods for experimental observations of noise sources, their localization and their frequency spectrum, voltage-current and thermal dependences. Our current knowledge of measurement methods for mesoscopic devices is summarized to identify directions for future research, related to downscaling effects. The directions for future research into fluctuation phenomena in quantum dot and quantum wire devices are specified. Nanoscale electronic devices will be the basic components for electronics of the 21st century. From this point of view the signal-to-noise ratio is a very important parameter for the device application. Since the noise is also a quality and reliability indicator, experimental methods will have a wide application in the future.
