الصفحة 55
الصفحة 55
70 Years of Levothyroxine
Presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy. It also describes the influence of levothyroxine on heart, bone and in cancer. When it was first synthesized in 1949, levothyroxine represented a significant advance in the treatment of hypothyroidism, providing a safe and effective treatment option for millions of hypothyroid patients around the globe. This synthetic form of thyroxine is now one of the most prescribed drugs in the world. Levothyroxine was first introduced by Merck KGaA,Darmstadt, Germany, in 1972, and since then the company has remained actively engaged in research on this mainstay of hypothyroidism treatment.
50 Years of EU Economic Dynamics : Integration, Financial Markets and Innovations
On the occasion of the 50th anniversary of the European Union experts present their analyses of historical developments and new economic challenges for the EU. After a reflection on historical dynamics, the contributors point out the dramatic economic shifts between Europe, Asia and the US. Representatives from major central banks (including the ECB), other leading banks, and academia analyze the dynamics of the Eurozone and financial market integration in the context of globalization and economic growth. Furthermore, the authors discuss the challenges of information and communication technologies by means of various country analyses. Moreover, the Schumpeterian prospects for Europe and the Lisbon Agenda, the long-term challenges of EU pension reforms, emission trading systems in the EU, and options for a new EU constitution are highlighted. At the bottom line of this EU analysis are major implications for investors, managers, policy-makers and the public at large in both the EU and the global economy.
3D imaging in endodontics : A new era in diagnosis and treatment
Full understanding of the role of cone beam computed tomography (CBCT) in helping to solve many of the most challenging problems in endodontics. It will shorten the learning curve in application of this exciting imaging technology in a variety of contexts: difficult diagnostic cases, treatment planning, evaluation of internal tooth anatomy prior to root canal therapy, nonsurgical and surgical treatments, early detection and treatment of resorptive defects, and outcomes assessment. The ability to obtain an accurate 3D representation of a tooth and the surrounding structures by means of noninvasive CBCT imaging is changing the approach to clinical decision making in endodontics. Clinicians long accustomed to working in very small, three-dimensional spaces are no longer constrained by the limitations of two-dimensional imaging. The challenges of mastering the new technology can, however, be daunting. The detailed guidance contained in this book will help endodontists to take full advantage of the important benefits offered by CBCT.
3-D Computer vision : Principles, algorithms and applications
Offers advanced content on computer vision (basic content can be found in its prerequisite textbook, “2D Computer Vision: Principles, Algorithms and Applications”), including the basic principles, typical methods and practical techniques. It is intended for graduate courses on related topics, e.g. Computer Vision, 3-D Computer Vision, Graphics, Artificial Intelligence, etc. The book is mainly based on my lecture notes for several undergraduate and graduate classes I have offered over the past several years, while a number of topics stem from my research publications co-authored with my students. This book takes into account the needs of learners with various professional backgrounds, as well as those of self-learners. Furthermore, it can be used as a reference guide for practitioners and professionals in related fields.
3D cell culture : Methods and protocols
Expands on the previous edition with discussions about the latest organoid models developed for many more organs; new hydrogels and devices for 3D culture; and the organoid systems that have been improved by incorporating more components of tissue microenvironments in the in vitro culture. The chapters in this book are organized into five parts and cover topics such as biofabrication, organoids, microfluidic systems, bioprinting, and image analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
.NET 2.0 Interoperability Recipes : A Problem-Solution Approach
.NET represents a new and improved way of developing software for the Windows platform. Given the chance, you'd probably rewrite all of your existing code in the newer managed code environment that .NET provides. But it is difficult or impossible to throw out all existing legacy code and start over when a new technology arrives. Instead, you need to find a way to move forward with new .NET development while reusing existing pieces of tested, working code. You need a way to interoperate with the existing code until you have a chance to finally rewrite all of it in .NET.
