الصفحة 52
الصفحة 52
Drawing architecture and the Urban
Provides an instrumental approach to drawing, especially computer-generated drawings; it outlines how drawings should be used to convey clear and analytical information in the process of design, as well as the communication and discussion of a project. In depth examples are provided how to communicate effectively. The final section demonstrates how to transform case-studies, directly connecting an analytical approach with the design process.
Double-stranded RNA : Methods and protocols
Examines classical and cutting-edge methods involving double-stranded RNA (dsRNA), specifically regarding isolation, visualization, characterization, production, and application. Many protocols, such as co-immunoprecipitation-based isolation of double-stranded RNA-associated protein complexes, identification of mycoviruses by dsRNA extraction, application of dsRNA for fungi disease management (Sclerotinia sclerotiorum and Botrytis cin), and production of double-stranded RNA in plants by plant viral vectors for gene silencing, can also be easily adapted for identification of viruses from other organisms, control of other pathogens, and fundamental research. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips for troubleshooting and avoiding known pitfalls.
DNA Methylation, Epigenetics and Metastasis
Provides an outline of the epigenetic mechanisms involved in cancer progression and the generation of metastasis. This book describes the tumor suppressor genes undergoing transcriptional silencing by CpG island promoter hypermethylation in the different tumor types of the human anatomy and their association with tumoral behaviour
DNA Methylation and Cancer Therapy
DNA methylation pat terns emerged as the only component of the chemical structure of DNA that exhibited tissue and cell specificity. This data seemingly provided an attrac tively simple explanation for the longstanding dilemma of how could one identical genome manifest itself in so many different forms in multicellular organisms? The DNA methylation pattern has thus become the only known factor to confer upon DNA a unique cellular identity.
DNA Methylation : Basic Mechanisms
The structural and functional importance of the correct patterns of DNA methylation in all parts of a mammalian genome is not well understood. The stability, inheritability, and developmental flexibility of these patterns point to a major role that these patterns appear to play in determining structure and function of the genome.
DNA Conformation and Transcription
the first book that compiles the fruits of the studies that have been performed to date to solve the riddle ‘written’ in DNA conformation ("conformation code"). This book provides a comprehensive overview of the field by covering history of the field, up-to-date topics, clarifications of present day research, and future perspective of what is still to be discovered. Thus, it serves as an invaluable source of information on the "conformation code".
Diverse Roles of Integrin Receptors in Articular Cartilage
Recent studies from the authors' laboratory and from other leading groups have shown that ß1-integrins are essential for cell signalling and communication in chondrocytes. Furthermore, ß1-integrins function as mechanoreceptors in the chondrocyte mechanotransduction pathway. Their expression is therefore essential for maintaining the chondrocyte phenotype, preventing chondrocyte apoptosis and regulating chondrocyte-specific gene expression. This book volume summarizes the work that the authors have done on ß1-integrins over the last 18 years and focuses on the expression and regulation of these proteins in chondrocytes and their role in the context of the unique function of chondrocytes within articular cartilage.
Distribution and phenotype of proliferating cells in the Forebrain of adult macaque monkeys after transient global cerebral ischemia
The authors' results show that ischemia differentially activates endogenous neural precursors residing in diverse locations of the adult primate central nervous system. A limited endogenous potential for postischemic neuronal repair exists in neocortex and striatum, but not in the hippocampus proper of the adult macaque monkey brain. The presence of putative parenchymal progenitors and of sustained progenitors in germinative centers opens novel possibilities for precursor cell recruitment.
Distributed Ledgers : Design and Regulation of Financial Infrastructure and Payment Systems
In this book, Robert Townsend steps back from the hype and controversy surrounding DLT (and the related, but not synonymous, innovations of blockchain and Bitcoin) to offer an economic analysis of what distributed ledgers can do and a blueprint for the optimal design and regulation of financial systems. He analyzes four crucial components of distributed ledgers—ledgers as accounts, e-messages and e-value transfers, cryptography, and contracts—assessing each in terms of both economics and computer science, and forges some middle ground. Relatedly, Townsend highlights hybrid systems in which some of these components allow useful innovation while legacy or alternative pieces deal with the problem of scale.
Distributed and Parallel Systems : Cluster and Grid Computing
DAPSY (Austrian-Hungarian Workshop on Distributed and Parallel Systems) is an international conference series with biannual events dedicated to all aspects of distributed and parallel computing. DAPSY started under a different name in 1992 (Sopron, Hungary) as regional meeting of Austrian and Hungarian researchers focusing on transputer-related parallel computing; a hot research topic of that time. A second workshop followed in 1994 (Budapest, Hungary). As transputers became history, the scope of the workshop widened to include parallel and distributed systems in general and the 1st DAPSYS in 1996 (Miskolc, Hungary) reflected the results of these changes.
Dissonant Heritages and Memories in Contemporary Europe
This book discusses political, economic, social, and humanitarian challenges that influence both how people deal with their past and how they build their identities in contemporary Europe. Ongoing debates on migration, on local, national, inter- and transnational levels, prove that it is a divisive issue with regards to understanding European integration and identity. At the same time, the European Union increasingly invests in projects related to European heritage, museums, and cultural memory networks, while having to take dissonant heritages into account. These processes in their combination offer an interesting dynamic and form the complex puzzle that poses challenging questions for anyone involved in academic research, heritage practices, and policy debates. With this puzzle at its core, this book explicitly focuses on slippery and transforming notions of Europe and critically discusses ongoing and transforming power structures of heritage and memory in today’s Europe.
Dissipative Solitons : From Optics to Biology and Medicine
The dissipative soliton concept is a fundamental extension of the concept of solitons in conservative and integrable systems. It includes ideas from three major sources, namely standard soliton theory developed since the 1960s, nonlinear dynamics theory, and Prigogine's ideas of systems far from equilibrium. These three sources also correspond to the three component parts of this novel paradigm. This book explains the above principles in detail and gives the reader various examples from optics, biology and medicine. These include laser systems, optical transmission lines, cortical networks, models of muscle contraction, localized vegetation structures and waves in brain tissues.
Dissipative Solitons
This volume is devoted to the exciting topic of dissipative solitons, i.e. pulses or spatially localised waves in systems exhibiting gain and loss. Examples are laser systems, nonlinear resonators and optical transmission lines. The physical principles and mathematical concepts are explained in a clear and concise way, suitable for students and young researchers. The similarities and differences in the notion of a soliton between dissipative systems and Hamiltonian and integrable systems are discussed, and many examples are given. The contributions are written by the world's leading experts in the field, making it a unique exposition of this emerging topic.
Disseminative Capabilities : A Case Study of Collaborative Product Development in the Automotive Industry
Nowadays, cooperating in Product Development seems to be a dominant strategy to lower costs and risks, to fully utilize capacities, and to gain access to lacking knowledge assets. Oppat analyzes cooperations in Product Development with a special focus on the automotive industry. He seeks answers to the question of how knowledge transfer between involved partners takes place. Although knowledge transfer and its success levers (e.g. absorptive capacity) are well-researched phenomena, equivalent investigations of the sender and her capabilities (DiC - Disseminative Capabilities) impacting inter-organizational transfer success are lacking. The in-depth case studies conducted concentrate on joint car development projects between Magna Steyr, an Austrian-based company, and German-based BMW, Mercedes Benz, and Audi. The research results clearly indicate that DiC have an impact on the knowledge transfer process and can explain why the analyzed projects differ in terms of transfer success. Based on the research findings, this work provides managerial implications for all eight dimensions of DiC and, by deploying insights from the empirical investigations, outlines ways to develop them successfully.
Disruptive trends in automation technology
The industrial sector is being transformed by the convergence of information technology and operational technology. The latter is another name for automation technology and covers established systems such as supervisory control and data acquisition (SCADA), programmable logic controllers (PLC), fieldbuses, and automation and control systems. As this technology is connected to the Internet and 5G networks, some monitoring, control, and analytic functionalities are deployed to the edge or cloud, and researchers are challenged to ensure the security, dependability, real-time performance, and maintainability of the resulting systems. The big data that is accessible from these systems create opportunities for artificial intelligence applications that can further disrupt the established practices in the automation domain.
Disorders of the Oral Cavity
The oral cavity is the part of the mouth behind the teeth and the gums surrounded by the soft palate, which is the movable layer hanging from the back of the hard palate and ending in the nasal cavity and under the tongue and the mucous membrane connecting it with the inner part of the jaw. It forms the first part of the digestive system. It is considered the entrance of food and drink into the digestive system and an entrance to the air into the respiratory system and it contains the teeth through which the chewing process begins, and on the tongue, which plays a fundamental role in the process of taste and swallowing and is also used by humans in speech to communicate with others, and animals use it to make sounds.
Disordered Materials : An Introduction
This self-contained text introduces the physics of structurally disordered condensed systems at the level of advanced undergraduate and graduate students. Among the topics are the geometry and symmetries of the structural units used as building blocks of extended structures, the various kinds of disorder, the phenomenology and the main theories of the glass transition, the structure of amorphous systems and the techniques to investigate it, the evolution of system's structure with its size (clusters) and the presence of orientational order in the absence of translational order (quasicrystals). In the second edition, the treatment of the mode coupling theory of the glass transition has been enlarged and connects now to a new section on collective excitations in disordered systems. Special attention has been devoted to nanometer-sized disordered systems, with emphasis on cluster-assembled materials. Questions of what governs the occurrence and stability of quasicrystals, the features of the amorphous to quasicrystal transformation and its reverse transition are discussed. The conditions leading to nano-quasicrystalline phases of technological interest are examined. Throughout the text relevant recent experimental and theoretical results are discussed so as to give readers insight into the currently most vibrant research topics.
Diseases of the Pancreas : Current Surgical Therapy
"Diseases of the Pancreas" is based on the latest comprehensive data about molecular mechanism of acute pancreatitis, chronic pancreatitis and pancreatic cancer. The diagnostic techniques including histology, radiology, sonography etc.
Discrete Geometry, Combinatorics and Graph Theory ; 7th China-Japan Conference, CJCDGCGT 2005, Tianjin, China, November 18-20, 2005, and Xi'an, China, November 22-24, 2005, Revised Selected Papers
Theis book includes discrete algorithmic geometry, combinatorics and graph theory
Discovering Biomolecular Mechanisms with Computational Biology
In this anthology, leading researchers present critical reviews of methods and high-impact applications in computational biology that lead to results that also non-bioinformaticians must know to design efficient experimental research plans. Discovering Biomolecular Mechanisms with Computational Biology also summarizes non-trivial theoretical predictions for regulatory and metabolic networks that have received experimental confirmation. Discovering Biomolecular Mechanisms with Computational Biology is essential reading for life science researchers and higher-level students that work on biomolecular mechanisms and wish to understand the impact of computational biology for their success.
